Click here to switch to the map view.

The map label for this gene is clpX

Identifier: 116492902

GI number: 116492902

Start: 1139801

End: 1141057

Strand: Reverse

Name: clpX

Synonym: PEPE_1141

Alternate gene names: 116492902

Gene position: 1141057-1139801 (Counterclockwise)

Preceding gene: 116492903

Following gene: 116492901

Centisome position: 62.27

GC content: 36.12

Gene sequence:

>1257_bases
TTGTTTGATGATCAACAAACGAATGAACCAGTTACTTGTTCTTTTTGTGGTAAGACCCAAGATCAAGTAAAGAAAATTAT
TGCTGGCCCAGATGTTTATATTTGTAACGAATGTGTTGATCTTTGCAAGGAAATCATTGATGAAGAGTTGGCTTCAGAAA
ACGCACCAACTGAAATCACGGATGTTCCAACTCCTGCAGAGATTGTAGATTATCTTAACCAATATGTTATTGGACAAGAA
GAAGCTAAAAAGACATTATCGGTTGCTGTATATAATCATTACAAACGAATCAATAAAATGGCTGAAACTAAAGCTGACGA
AGATGAACCAGAACTCCAGAAAAGTAATATTAGTTTAATTGGACCTACTGGTTCAGGAAAAACTTTCTTGGCTCAAAGTT
TGGCTAAAATTTTAAATGTACCTTTTGCGATTGCCGATGCAACCACATTGACGGAAGCAGGGTATGTTGGTGAAGATGTC
GAAAATATTCTACTTAAGTTATTGCAAAATGCGGACTACAATGTTGAAGCTGCAGAACGTGGAATAATTTATATTGATGA
AATTGATAAAATCGCTAAGAAAAGCGAAAATGTGTCAATTACTCGTGATGTTTCCGGTGAAGGTGTGCAACAAGCCCTTT
TAAAAATCCTAGAAGGAACAATTGCTAATGTTCCACCTCAAGGAGGAAGAAAACATCCACAACAAGAGTTTATCCAAATT
AATACGACGAACATCTTATTCATTGTTGGTGGTGCTTTCGATGGCATCGAGACAATTGTTAAAAATCGTTTAGGTGATAA
GACCATTGGTTTTGGTACAAATGCAAGTACCACTGTTGAAGAAGATAAGAGTTTAATGCAACAAGTTATTCCAGAAGATT
TGCTTAACTTTGGTTTAATCCCAGAATTTATTGGACGTTTACCAATTCTTTCAGCATTGGAAAAACTAACTGAGGAAGAT
CTTGTTCATATCTTAACAGAGCCTAAGAATGCGTTAGTTAAGCAATATAAGACGTTATTAGGTCTAGATGGCGTAGAACT
TAAATTTACACCACAGGCCTTGCATGCGATTGCTAACCAAGCTATTAGTCGTAATACTGGTGCTCGTGGATTAAGATCAA
TTATTGAAAATGTCATGCGAGATATCATGTTTGAAATTCCTTCTCGCAATGATGTTGCAAAAGTTACGGTAAATAAAAAG
ACTGTTATTGAAGGTGCGGAACCTGAAGTTGAGTTAATCGACGAACAAGCATCGTAG

Upstream 100 bases:

>100_bases
ATCGTTTTTGTTTATTAACCACTAAAGTTATAGAAATTGGCTTATAGTCGTTTATTTTGCTATGATGATAGTGGTAAAAA
TCATTTGAGAGGTGACAGAA

Downstream 100 bases:

>100_bases
TCTAAGTTTTAAGAATCAGGCTATAAGTTCCTTTAGTCTGGTTCTTTTTTTGTTGATCCATGTTATCATTAAAAGCAGAA
ATTGGAAGGTGGAGAAGTAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MFDDQQTNEPVTCSFCGKTQDQVKKIIAGPDVYICNECVDLCKEIIDEELASENAPTEITDVPTPAEIVDYLNQYVIGQE
EAKKTLSVAVYNHYKRINKMAETKADEDEPELQKSNISLIGPTGSGKTFLAQSLAKILNVPFAIADATTLTEAGYVGEDV
ENILLKLLQNADYNVEAAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQI
NTTNILFIVGGAFDGIETIVKNRLGDKTIGFGTNASTTVEEDKSLMQQVIPEDLLNFGLIPEFIGRLPILSALEKLTEED
LVHILTEPKNALVKQYKTLLGLDGVELKFTPQALHAIANQAISRNTGARGLRSIIENVMRDIMFEIPSRNDVAKVTVNKK
TVIEGAEPEVELIDEQAS

Sequences:

>Translated_418_residues
MFDDQQTNEPVTCSFCGKTQDQVKKIIAGPDVYICNECVDLCKEIIDEELASENAPTEITDVPTPAEIVDYLNQYVIGQE
EAKKTLSVAVYNHYKRINKMAETKADEDEPELQKSNISLIGPTGSGKTFLAQSLAKILNVPFAIADATTLTEAGYVGEDV
ENILLKLLQNADYNVEAAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQI
NTTNILFIVGGAFDGIETIVKNRLGDKTIGFGTNASTTVEEDKSLMQQVIPEDLLNFGLIPEFIGRLPILSALEKLTEED
LVHILTEPKNALVKQYKTLLGLDGVELKFTPQALHAIANQAISRNTGARGLRSIIENVMRDIMFEIPSRNDVAKVTVNKK
TVIEGAEPEVELIDEQAS
>Mature_418_residues
MFDDQQTNEPVTCSFCGKTQDQVKKIIAGPDVYICNECVDLCKEIIDEELASENAPTEITDVPTPAEIVDYLNQYVIGQE
EAKKTLSVAVYNHYKRINKMAETKADEDEPELQKSNISLIGPTGSGKTFLAQSLAKILNVPFAIADATTLTEAGYVGEDV
ENILLKLLQNADYNVEAAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQI
NTTNILFIVGGAFDGIETIVKNRLGDKTIGFGTNASTTVEEDKSLMQQVIPEDLLNFGLIPEFIGRLPILSALEKLTEED
LVHILTEPKNALVKQYKTLLGLDGVELKFTPQALHAIANQAISRNTGARGLRSIIENVMRDIMFEIPSRNDVAKVTVNKK
TVIEGAEPEVELIDEQAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=327, Percent_Identity=49.5412844036697, Blast_Score=312, Evalue=4e-85,
Organism=Escherichia coli, GI1786642, Length=397, Percent_Identity=60.2015113350126, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1790366, Length=212, Percent_Identity=34.4339622641509, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71982905, Length=319, Percent_Identity=44.5141065830721, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71982908, Length=319, Percent_Identity=44.5141065830721, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=38.2051282051282, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=41.1067193675889, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=441, Percent_Identity=39.4557823129252, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24648291, Length=315, Percent_Identity=47.9365079365079, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24648289, Length=315, Percent_Identity=47.9365079365079, Blast_Score=298, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PEDPA (Q03F27)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804637.1
- ProteinModelPortal:   Q03F27
- STRING:   Q03F27
- GeneID:   4417823
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1141
- NMPDR:   fig|278197.10.peg.1002
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q03F27
- ProtClustDB:   PRK05342
- BioCyc:   PPEN278197:PEPE_1141-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45898; Mature: 45898

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDDQQTNEPVTCSFCGKTQDQVKKIIAGPDVYICNECVDLCKEIIDEELASENAPTEIT
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
DVPTPAEIVDYLNQYVIGQEEAKKTLSVAVYNHYKRINKMAETKADEDEPELQKSNISLI
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEE
GPTGSGKTFLAQSLAKILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYNVEAAER
CCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHC
GIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQI
CEEEEHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEE
NTTNILFIVGGAFDGIETIVKNRLGDKTIGFGTNASTTVEEDKSLMQQVIPEDLLNFGLI
ECCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
PEFIGRLPILSALEKLTEEDLVHILTEPKNALVKQYKTLLGLDGVELKFTPQALHAIANQ
HHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
AISRNTGARGLRSIIENVMRDIMFEIPSRNDVAKVTVNKKTVIEGAEPEVELIDEQAS
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCCCHHHHCCCCC
>Mature Secondary Structure
MFDDQQTNEPVTCSFCGKTQDQVKKIIAGPDVYICNECVDLCKEIIDEELASENAPTEIT
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCC
DVPTPAEIVDYLNQYVIGQEEAKKTLSVAVYNHYKRINKMAETKADEDEPELQKSNISLI
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEE
GPTGSGKTFLAQSLAKILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYNVEAAER
CCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHC
GIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQI
CEEEEHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEE
NTTNILFIVGGAFDGIETIVKNRLGDKTIGFGTNASTTVEEDKSLMQQVIPEDLLNFGLI
ECCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCH
PEFIGRLPILSALEKLTEEDLVHILTEPKNALVKQYKTLLGLDGVELKFTPQALHAIANQ
HHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
AISRNTGARGLRSIIENVMRDIMFEIPSRNDVAKVTVNKKTVIEGAEPEVELIDEQAS
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA