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The map label for this gene is catR [H]

Identifier: 116492808

GI number: 116492808

Start: 1038292

End: 1039197

Strand: Direct

Name: catR [H]

Synonym: PEPE_1045

Alternate gene names: 116492808

Gene position: 1038292-1039197 (Clockwise)

Preceding gene: 116492807

Following gene: 116492810

Centisome position: 56.66

GC content: 31.35

Gene sequence:

>906_bases
ATGAATTTAACAACATTAGAATACTTCGTTCAAGTAGCAACAGAAGGAAGCCTAACTAAGGCTGCTGATAAACTTTTTAT
TTCTCAACCTACTTTAAGCCGTCACATGAAAAATTTGGAAGCTGAATTAAATACTCAACTATTTGTTCGTCAAAGTCATT
CTCTAAAACTCACCGAAAATGGGATTACTTTTTTAAAAGCTACGACAAAAGTAATCCAAGACGTAGATGCATTAAAACAT
TTCTTTGATCAACACCAAACAGCTAGCAATCCAACTCACTACCTTAATGTGGGCTATTTAGAAAATTTTCGTTTAGAAAA
AATGTATGCAGTCCTGGACCAAATTAGTCATGAGAATAATATTCAGTTCTCGCTCTTTCCAGACACCCCAACTAATTTAT
CCAAAGGTTTATCTTCTGGTAAATATGACTTGATTTACTCTTTAAGACCCTATACCACTGACAATGTATTGTTTAAAAGC
ACGGATTTTTTAGAAAATCATCTTCAGATTGCATTACCAATTAATCATCCTTTAGCCATGAAACCACAACTTTCGTTTTC
CGATTTAAAAAATGAAACTTTTATTTTATTAGATCGAGATAAATCACCAATTATTGTCGACAATGTGTTAAGTCAAGGAA
TCAAAAATGGCTACAATTTAAAAGCAAATTATTATGTTAAAAATTTAAGTCAGGGACTTTCAATGACAGCATTGGGAAAT
GGATTAGCCTTCCTATATTCTGCAATGAATGACGGCCAATTGGAAAAACAATACCGTATAAAAATTAAAGATTTAACCGA
TAATTTTGGTAATCAAAATATTGTGATCGCAATGAAACGTTCCGTAGATAATGCATTGATTGGATCTATTTTCGAAAAAA
TAATCGATACTAAAAAAAATAGATAA

Upstream 100 bases:

>100_bases
TACAATTACCTATCTTAAAAAAATAGAAAAGAATTTAGTTGCTTAACTAAAGGATTTGTAGTATTAATGACTATAAATCC
TTTTTTTGATTGGAGTCACA

Downstream 100 bases:

>100_bases
GCTAGTTAACTAGCTTATCTATTTTTGTATTTTCACAATAAAAAGTCATGCTCTAGCTCTAAAAGGTTTAGTTATTTATG
AAAACTCTTACTTCCTAAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: CatBC operon transcriptional activator [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNLTTLEYFVQVATEGSLTKAADKLFISQPTLSRHMKNLEAELNTQLFVRQSHSLKLTENGITFLKATTKVIQDVDALKH
FFDQHQTASNPTHYLNVGYLENFRLEKMYAVLDQISHENNIQFSLFPDTPTNLSKGLSSGKYDLIYSLRPYTTDNVLFKS
TDFLENHLQIALPINHPLAMKPQLSFSDLKNETFILLDRDKSPIIVDNVLSQGIKNGYNLKANYYVKNLSQGLSMTALGN
GLAFLYSAMNDGQLEKQYRIKIKDLTDNFGNQNIVIAMKRSVDNALIGSIFEKIIDTKKNR

Sequences:

>Translated_301_residues
MNLTTLEYFVQVATEGSLTKAADKLFISQPTLSRHMKNLEAELNTQLFVRQSHSLKLTENGITFLKATTKVIQDVDALKH
FFDQHQTASNPTHYLNVGYLENFRLEKMYAVLDQISHENNIQFSLFPDTPTNLSKGLSSGKYDLIYSLRPYTTDNVLFKS
TDFLENHLQIALPINHPLAMKPQLSFSDLKNETFILLDRDKSPIIVDNVLSQGIKNGYNLKANYYVKNLSQGLSMTALGN
GLAFLYSAMNDGQLEKQYRIKIKDLTDNFGNQNIVIAMKRSVDNALIGSIFEKIIDTKKNR
>Mature_301_residues
MNLTTLEYFVQVATEGSLTKAADKLFISQPTLSRHMKNLEAELNTQLFVRQSHSLKLTENGITFLKATTKVIQDVDALKH
FFDQHQTASNPTHYLNVGYLENFRLEKMYAVLDQISHENNIQFSLFPDTPTNLSKGLSSGKYDLIYSLRPYTTDNVLFKS
TDFLENHLQIALPINHPLAMKPQLSFSDLKNETFILLDRDKSPIIVDNVLSQGIKNGYNLKANYYVKNLSQGLSMTALGN
GLAFLYSAMNDGQLEKQYRIKIKDLTDNFGNQNIVIAMKRSVDNALIGSIFEKIIDTKKNR

Specific function: Positive regulator of the catBC operon that degrades catechol to acetyl-CoA. CatR binds in trans to the catR-catBC promoter-control region in the presence or absence of inducer but only activates the catBC operon in the presence of the inducer, cis-cis-mu

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=24.7967479674797, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367136, Length=284, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=194, Percent_Identity=25.2577319587629, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788887, Length=202, Percent_Identity=25.2475247524752, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787806, Length=147, Percent_Identity=29.2517006802721, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=210, Percent_Identity=26.1904761904762, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34181; Mature: 34181

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTTLEYFVQVATEGSLTKAADKLFISQPTLSRHMKNLEAELNTQLFVRQSHSLKLTEN
CCCHHHHHHHHHHCCCCHHHHHHHHEECCCHHHHHHHHHHHHCCCEEEEEECCCEEEECC
GITFLKATTKVIQDVDALKHFFDQHQTASNPTHYLNVGYLENFRLEKMYAVLDQISHENN
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
IQFSLFPDTPTNLSKGLSSGKYDLIYSLRPYTTDNVLFKSTDFLENHLQIALPINHPLAM
EEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCEEECCHHHHCCCEEEEEECCCCEEC
KPQLSFSDLKNETFILLDRDKSPIIVDNVLSQGIKNGYNLKANYYVKNLSQGLSMTALGN
CCCCCHHHCCCCEEEEEECCCCCEEHHHHHHHHHCCCCCEEEEEEHHHHHCCCEEEECCC
GLAFLYSAMNDGQLEKQYRIKIKDLTDNFGNQNIVIAMKRSVDNALIGSIFEKIIDTKKN
CHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
R
C
>Mature Secondary Structure
MNLTTLEYFVQVATEGSLTKAADKLFISQPTLSRHMKNLEAELNTQLFVRQSHSLKLTEN
CCCHHHHHHHHHHCCCCHHHHHHHHEECCCHHHHHHHHHHHHCCCEEEEEECCCEEEECC
GITFLKATTKVIQDVDALKHFFDQHQTASNPTHYLNVGYLENFRLEKMYAVLDQISHENN
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
IQFSLFPDTPTNLSKGLSSGKYDLIYSLRPYTTDNVLFKSTDFLENHLQIALPINHPLAM
EEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCEEECCHHHHCCCEEEEEECCCCEEC
KPQLSFSDLKNETFILLDRDKSPIIVDNVLSQGIKNGYNLKANYYVKNLSQGLSMTALGN
CCCCCHHHCCCCEEEEEECCCCCEEHHHHHHHHHCCCCCEEEEEEHHHHHCCCEEEECCC
GLAFLYSAMNDGQLEKQYRIKIKDLTDNFGNQNIVIAMKRSVDNALIGSIFEKIIDTKKN
CHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1688844 [H]