Click here to switch to the map view.

The map label for this gene is pyrR

Identifier: 116492706

GI number: 116492706

Start: 942917

End: 943450

Strand: Direct

Name: pyrR

Synonym: PEPE_0942

Alternate gene names: 116492706

Gene position: 942917-943450 (Clockwise)

Preceding gene: 116492705

Following gene: 116492707

Centisome position: 51.46

GC content: 36.89

Gene sequence:

>534_bases
ATGGAAAAAGAAATTATGGATGCCATGGCAATGAAAAGGGCTTTAACAAGAATTACTTATGAAATTATCGAACGTAATAA
AGGGGTCGAAGACATCGTATTGATTGGTATAAAAACGCGTGGTGTTTTTATTGCTAAGCGAATTGCTGAACGTCTGAAAC
AACTTGAAAATTTTGACATTCCAGTTGGTGAATTGGATATAGCTGAATACCGTGATGATCAACGTAATTCAGCTGAACCA
CGTTCAACTAAAGCTAATTCTAGTCTTGCTAAACTTGATTTAAAGGATCGAAAAGTGATTTTGATTGATGATGTTCTCTA
TACTGGACGAACAATCCGCGCTGCTATGGACGCAATTATGGATATTAACCGTCCAGCTCAAATTAGTTTAGCGGTTCTTG
TCGATCGTGGACATCGGGAATTACCAATTCGTGCTGATTTTGTGGGTAAGAATATTCCAACAGCACAAAACGAGAAAATT
AACGTTTTTGTCCGCGAAATTGATGATGAAGACGTTGTTCTCTTAGAAAATTAA

Upstream 100 bases:

>100_bases
TATATACTTATAAAATAATGTTAGATTAAGGTTAGGAGTTCCAATTACTGATATAATTGAATTAGTGAGTTTTTGAAAGA
AGAAGGAGGACTTGGCGAGT

Downstream 100 bases:

>100_bases
CATGATTTAACTGTGGAGGTGGCTATTATGGCAGACCGATATTTAATATTAGAAGACGGTTCCGTTTTTAAGGGTAAAGC
ATTCGGATCGCGAGCAACCA

Product: pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MEKEIMDAMAMKRALTRITYEIIERNKGVEDIVLIGIKTRGVFIAKRIAERLKQLENFDIPVGELDIAEYRDDQRNSAEP
RSTKANSSLAKLDLKDRKVILIDDVLYTGRTIRAAMDAIMDINRPAQISLAVLVDRGHRELPIRADFVGKNIPTAQNEKI
NVFVREIDDEDVVLLEN

Sequences:

>Translated_177_residues
MEKEIMDAMAMKRALTRITYEIIERNKGVEDIVLIGIKTRGVFIAKRIAERLKQLENFDIPVGELDIAEYRDDQRNSAEP
RSTKANSSLAKLDLKDRKVILIDDVLYTGRTIRAAMDAIMDINRPAQISLAVLVDRGHRELPIRADFVGKNIPTAQNEKI
NVFVREIDDEDVVLLEN
>Mature_177_residues
MEKEIMDAMAMKRALTRITYEIIERNKGVEDIVLIGIKTRGVFIAKRIAERLKQLENFDIPVGELDIAEYRDDQRNSAEP
RSTKANSSLAKLDLKDRKVILIDDVLYTGRTIRAAMDAIMDINRPAQISLAVLVDRGHRELPIRADFVGKNIPTAQNEKI
NVFVREIDDEDVVLLEN

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_PEDPA (Q03FM3)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804441.1
- ProteinModelPortal:   Q03FM3
- SMR:   Q03FM3
- STRING:   Q03FM3
- GeneID:   4417754
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0942
- NMPDR:   fig|278197.10.peg.836
- eggNOG:   COG2065
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- BioCyc:   PPEN278197:PEPE_0942-MONOMER
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20175; Mature: 20175

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEIMDAMAMKRALTRITYEIIERNKGVEDIVLIGIKTRGVFIAKRIAERLKQLENFDI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCC
PVGELDIAEYRDDQRNSAEPRSTKANSSLAKLDLKDRKVILIDDVLYTGRTIRAAMDAIM
CCCCEEHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECHHHCCHHHHHHHHHHH
DINRPAQISLAVLVDRGHRELPIRADFVGKNIPTAQNEKINVFVREIDDEDVVLLEN
CCCCCCEEEEEEEEECCCCCCCEEHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEEC
>Mature Secondary Structure
MEKEIMDAMAMKRALTRITYEIIERNKGVEDIVLIGIKTRGVFIAKRIAERLKQLENFDI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCC
PVGELDIAEYRDDQRNSAEPRSTKANSSLAKLDLKDRKVILIDDVLYTGRTIRAAMDAIM
CCCCEEHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECHHHCCHHHHHHHHHHH
DINRPAQISLAVLVDRGHRELPIRADFVGKNIPTAQNEKINVFVREIDDEDVVLLEN
CCCCCCEEEEEEEEECCCCCCCEEHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA