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The map label for this gene is cdsA [H]

Identifier: 116492648

GI number: 116492648

Start: 880537

End: 881364

Strand: Direct

Name: cdsA [H]

Synonym: PEPE_0882

Alternate gene names: 116492648

Gene position: 880537-881364 (Clockwise)

Preceding gene: 116492647

Following gene: 116492649

Centisome position: 48.05

GC content: 37.8

Gene sequence:

>828_bases
GTGATCGACGTTTTGGTGCAATTAAAAAGTGAGGAATTAATTTTGAAGCAAAGAGTAATTACTGCCGTAGTAGCGTTAAT
AATTTTTATTCCAATTGTCTTTCTTGGAGGAACATTAATCGAGATTGCAGCCTTGGCCCTAGCCGTGGTGGCAATGAGTG
AAGTTTTAATTATGAAACGAATTTTGTTGGTAACTCCTGAAGCAATTATTAGTATCTTAGGAACGTTATTCTTGGTTGCC
CCTAAGTCATGGATGCACGACTTACCAAGCCAAATTAATACACCATTTGTTTCTTTGATTTTTGCCATTGCGTTGATGGT
GAGAGTTGTTTTCAGTAAAAATCGTTTCAATTTCGATGATGCTGGTGTATTAACATTGACAATGCTATACATTGGATTCG
GATTTAACATGTTTGTTCAAGCTCGAACGGTGGGCTTAGGAATGTTAATGTATCTGCTACTAACCGTCTGGAGTACAGAC
AGTGGAGCCTACTTAGTCGGAAGAAAGATTGGTAAGACTAAACTTGCTCCTCAAATTAGCCCCAATAAGACTTGGGAAGG
TTCCATTGGCGGAACCATAGTTGCAGTTATTGTTGGAATTATTTTCTCAGTAACGGGACTAATCCATTATGGAATTCTAG
CTACAATTTTAATGACGCTATTCCTTTCAATTGCAGGTCAGTTAGGAGACTTAGTAGAATCTTCTCTTAAACGTTATTAC
GGTGTTAAAGATTCTGGTCGCATCTTACCAGGTCATGGAGGAATCCTTGACCGTTTTGATAGTCTATTGCTAGTATTGCC
AATGGCATATTTATTAGGTTTACTATAA

Upstream 100 bases:

>100_bases
CTTTGGCAAATTGCATATAGTGAGTTAGTCTTTACTGACACACTTTGGCCAGATTTCGACGAAAAAATCTTTATTGAAAT
GATAAAAGAGTATCAAAAAC

Downstream 100 bases:

>100_bases
AATCTGCCAGTTAGGAGTTATTTATGATAACTACGATTATTACCTTTATTGTTGTATTTTTAATTTTAGTTGTTGTCCAT
GAGTATGGGCATTTTGTTGC

Product: CDP-diglyceride synthetase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MIDVLVQLKSEELILKQRVITAVVALIIFIPIVFLGGTLIEIAALALAVVAMSEVLIMKRILLVTPEAIISILGTLFLVA
PKSWMHDLPSQINTPFVSLIFAIALMVRVVFSKNRFNFDDAGVLTLTMLYIGFGFNMFVQARTVGLGMLMYLLLTVWSTD
SGAYLVGRKIGKTKLAPQISPNKTWEGSIGGTIVAVIVGIIFSVTGLIHYGILATILMTLFLSIAGQLGDLVESSLKRYY
GVKDSGRILPGHGGILDRFDSLLLVLPMAYLLGLL

Sequences:

>Translated_275_residues
MIDVLVQLKSEELILKQRVITAVVALIIFIPIVFLGGTLIEIAALALAVVAMSEVLIMKRILLVTPEAIISILGTLFLVA
PKSWMHDLPSQINTPFVSLIFAIALMVRVVFSKNRFNFDDAGVLTLTMLYIGFGFNMFVQARTVGLGMLMYLLLTVWSTD
SGAYLVGRKIGKTKLAPQISPNKTWEGSIGGTIVAVIVGIIFSVTGLIHYGILATILMTLFLSIAGQLGDLVESSLKRYY
GVKDSGRILPGHGGILDRFDSLLLVLPMAYLLGLL
>Mature_275_residues
MIDVLVQLKSEELILKQRVITAVVALIIFIPIVFLGGTLIEIAALALAVVAMSEVLIMKRILLVTPEAIISILGTLFLVA
PKSWMHDLPSQINTPFVSLIFAIALMVRVVFSKNRFNFDDAGVLTLTMLYIGFGFNMFVQARTVGLGMLMYLLLTVWSTD
SGAYLVGRKIGKTKLAPQISPNKTWEGSIGGTIVAVIVGIIFSVTGLIHYGILATILMTLFLSIAGQLGDLVESSLKRYY
GVKDSGRILPGHGGILDRFDSLLLVLPMAYLLGLL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=120, Percent_Identity=44.1666666666667, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787677, Length=113, Percent_Identity=44.2477876106195, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29868; Mature: 29868

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00589 PTS_HPR_SER ; PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA