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The map label for this gene is fabD [H]

Identifier: 116492623

GI number: 116492623

Start: 860726

End: 861658

Strand: Direct

Name: fabD [H]

Synonym: PEPE_0857

Alternate gene names: 116492623

Gene position: 860726-861658 (Clockwise)

Preceding gene: 116492622

Following gene: 116492624

Centisome position: 46.97

GC content: 38.48

Gene sequence:

>933_bases
ATGGTTAAAGCGGCTTATTTATTTAGCGGACAAGGACAACAATTTGAAGGGATGGGAATGGATCTGTATCAAACAGAACC
GGCCTACCGAGCATTAGTTGATGAAGCTAGTCAAATTTTAGGTCAAAATTTTGCTAAACAAGATGTTATTGATAATGAAG
AAAATTTACAATTATCAATTGTTATTTTGAGTTTAGGAATTGCACGAATTCTTAGCAGTGAAAAGATTGCACCGCAGAAG
TTCTTGGGGCTTAGCTTAGGTGAATATTCCGCTTTGATTGCCGCAAATGGTTTTTCAATTGATGAAGGTTTAAAAGTTCT
TGAAGATCGTTCAAAATACATGGCTGAAGCAGGGAAACTAAATCCAGGCCAAATGGTAGCAGTTTTAAATGCCAGTGATG
ATGTGATGAACGAGGCAATGCATGCTGCCCGAGAGTTTGGTAAGGTTTATCCAGCAAATTACAACACACCTAAGCAAACG
GTTTTCGGTGGCGATGCCGCTGGAATCAACAAGTTTAGTGCACTATTAAAAGCTGCTGGAGTTAAGCGGGTTGTTCCAAT
TAAGATGAGTGTGGCATCACACACACCATTTATGCAAATGGCTAGTGATAACTTGAAGACCCGTTTGGAAAATGTCACAG
TAGCTCAACCGAATGTGCCAGTAATTAGCAATACGATCAAGACTGAATTTACTAAAGCTAATATTAAACAAACCCTTGCA
GACCAGTTGGTAAACCCAACTTATTTCACGGATTGTTTAGCTGTAATTGAGGCAGATCCAATCGATTGTTTGGTAGAAAT
TGGTCCTGGCAAAGCGCTCAGTGGATTTGCTAAAAAAACTCTCAAGAACAAAGACTTACCAATTTTCAATGTTTATGATG
TTGAAACACTACAAAAATTACGGAACTATCTTTCAAAGCAGGAGGCTAATTAA

Upstream 100 bases:

>100_bases
TTGATATCGATATTGATACAGACGAAAATATGGATACTGTTGGCAAGTTAGTTGATTACGTTAGCGAAAACATCGATAAG
TAATTAAAAAGGGGTAAATG

Downstream 100 bases:

>100_bases
GTGATTATTAAAGATACAGTGGCAGTTGTTACTGGTGGAACTCAAGGAATCGGATTAGCAATCGCAATGGATTTAGCTAA
GAAAGGTTCAAAGGTTTTTA

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVKAAYLFSGQGQQFEGMGMDLYQTEPAYRALVDEASQILGQNFAKQDVIDNEENLQLSIVILSLGIARILSSEKIAPQK
FLGLSLGEYSALIAANGFSIDEGLKVLEDRSKYMAEAGKLNPGQMVAVLNASDDVMNEAMHAAREFGKVYPANYNTPKQT
VFGGDAAGINKFSALLKAAGVKRVVPIKMSVASHTPFMQMASDNLKTRLENVTVAQPNVPVISNTIKTEFTKANIKQTLA
DQLVNPTYFTDCLAVIEADPIDCLVEIGPGKALSGFAKKTLKNKDLPIFNVYDVETLQKLRNYLSKQEAN

Sequences:

>Translated_310_residues
MVKAAYLFSGQGQQFEGMGMDLYQTEPAYRALVDEASQILGQNFAKQDVIDNEENLQLSIVILSLGIARILSSEKIAPQK
FLGLSLGEYSALIAANGFSIDEGLKVLEDRSKYMAEAGKLNPGQMVAVLNASDDVMNEAMHAAREFGKVYPANYNTPKQT
VFGGDAAGINKFSALLKAAGVKRVVPIKMSVASHTPFMQMASDNLKTRLENVTVAQPNVPVISNTIKTEFTKANIKQTLA
DQLVNPTYFTDCLAVIEADPIDCLVEIGPGKALSGFAKKTLKNKDLPIFNVYDVETLQKLRNYLSKQEAN
>Mature_310_residues
MVKAAYLFSGQGQQFEGMGMDLYQTEPAYRALVDEASQILGQNFAKQDVIDNEENLQLSIVILSLGIARILSSEKIAPQK
FLGLSLGEYSALIAANGFSIDEGLKVLEDRSKYMAEAGKLNPGQMVAVLNASDDVMNEAMHAAREFGKVYPANYNTPKQT
VFGGDAAGINKFSALLKAAGVKRVVPIKMSVASHTPFMQMASDNLKTRLENVTVAQPNVPVISNTIKTEFTKANIKQTLA
DQLVNPTYFTDCLAVIEADPIDCLVEIGPGKALSGFAKKTLKNKDLPIFNVYDVETLQKLRNYLSKQEAN

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=322, Percent_Identity=27.3291925465839, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=32.5259515570934, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=24.2524916943522, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71984332, Length=265, Percent_Identity=27.5471698113208, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24665753, Length=310, Percent_Identity=27.4193548387097, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33779; Mature: 33779

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAAYLFSGQGQQFEGMGMDLYQTEPAYRALVDEASQILGQNFAKQDVIDNEENLQLSI
CCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEE
VILSLGIARILSSEKIAPQKFLGLSLGEYSALIAANGFSIDEGLKVLEDRSKYMAEAGKL
HHHHHHHHHHHHCCCCCHHHHHCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
NPGQMVAVLNASDDVMNEAMHAAREFGKVYPANYNTPKQTVFGGDAAGINKFSALLKAAG
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCC
VKRVVPIKMSVASHTPFMQMASDNLKTRLENVTVAQPNVPVISNTIKTEFTKANIKQTLA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCEEECCCCCEEHHHHHHHHHHHHHHHHHH
DQLVNPTYFTDCLAVIEADPIDCLVEIGPGKALSGFAKKTLKNKDLPIFNVYDVETLQKL
HHHCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHH
RNYLSKQEAN
HHHHHHCCCC
>Mature Secondary Structure
MVKAAYLFSGQGQQFEGMGMDLYQTEPAYRALVDEASQILGQNFAKQDVIDNEENLQLSI
CCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEE
VILSLGIARILSSEKIAPQKFLGLSLGEYSALIAANGFSIDEGLKVLEDRSKYMAEAGKL
HHHHHHHHHHHHCCCCCHHHHHCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
NPGQMVAVLNASDDVMNEAMHAAREFGKVYPANYNTPKQTVFGGDAAGINKFSALLKAAG
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCC
VKRVVPIKMSVASHTPFMQMASDNLKTRLENVTVAQPNVPVISNTIKTEFTKANIKQTLA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCEEECCCCCEEHHHHHHHHHHHHHHHHHH
DQLVNPTYFTDCLAVIEADPIDCLVEIGPGKALSGFAKKTLKNKDLPIFNVYDVETLQKL
HHHCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHH
RNYLSKQEAN
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]