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The map label for this gene is rpe [H]

Identifier: 116492601

GI number: 116492601

Start: 840334

End: 840981

Strand: Direct

Name: rpe [H]

Synonym: PEPE_0834

Alternate gene names: 116492601

Gene position: 840334-840981 (Clockwise)

Preceding gene: 116492600

Following gene: 116492602

Centisome position: 45.86

GC content: 37.81

Gene sequence:

>648_bases
ATGATTAAAGTAGCCCCATCAATTTTAAGTGCAGACCCAGCTAACTTAATGGGTGATATTAATAAAGTAGAAGGAGCGGA
CTATCTTCACGTTGATGTGATGGATGGTAGCTTCGTACCTAACTTAAGTTTTGGACTAAATACAGTTCAAGGATTGTCAA
AAGATACAGATATCAAATTAGACGTACATTTGATGATTCAAAATCCAGAAAACTATGTTGAACAATTTGTTAAAGCCGGT
GCAAGTATTGTTGGTGTTCATGTTGAAAGTACTCAGCATATTGCACGAGCAATCCAAATTATCAAAAATGCTGGAGCTCG
CGCTGAAGTAGTAGTTAACCCTGGAACTCCATTAACAGAATTAGAAGAACTATTACCCGAAATTGACCAAGTTTTGATTA
TGTCGGTTAACCCAGGTTTTGGTGGACAAAAGTTTCTTGAAAGCTCAATCAGCAAGGTTAAGCGACTATCTGCATTACGC
CAAGCACGTGGATTAGAATTTGATATTGAAATTGATGGTGGGATTTCAGACAAAAATATCAAAGCGGTCTATGATGCTGG
CGTAGATGTAGCCGTTGCTGGTTCATACGTTTTCGGCGCTGAAGATTACACCAAACAAGTGCAACTATTAAAGGAACTTA
CAAAATAA

Upstream 100 bases:

>100_bases
GCCGTTATGCTAATTATGAACAGTTTATCGAACTGATTCGGAATCAAAAACCTGAATATAAGCGTAAAGGTTATCAAAAA
AAGGACCGGAGGAAGAAGAA

Downstream 100 bases:

>100_bases
TGAAAATTTTTAACTTATTAGTTGGTGGAGCTCCAGAAAATTTACCTGATAATTTAAATGATTTTGAAGGAGATTGGATT
GGAGTAGATCGTGGAGCTTT

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIKVAPSILSADPANLMGDINKVEGADYLHVDVMDGSFVPNLSFGLNTVQGLSKDTDIKLDVHLMIQNPENYVEQFVKAG
ASIVGVHVESTQHIARAIQIIKNAGARAEVVVNPGTPLTELEELLPEIDQVLIMSVNPGFGGQKFLESSISKVKRLSALR
QARGLEFDIEIDGGISDKNIKAVYDAGVDVAVAGSYVFGAEDYTKQVQLLKELTK

Sequences:

>Translated_215_residues
MIKVAPSILSADPANLMGDINKVEGADYLHVDVMDGSFVPNLSFGLNTVQGLSKDTDIKLDVHLMIQNPENYVEQFVKAG
ASIVGVHVESTQHIARAIQIIKNAGARAEVVVNPGTPLTELEELLPEIDQVLIMSVNPGFGGQKFLESSISKVKRLSALR
QARGLEFDIEIDGGISDKNIKAVYDAGVDVAVAGSYVFGAEDYTKQVQLLKELTK
>Mature_215_residues
MIKVAPSILSADPANLMGDINKVEGADYLHVDVMDGSFVPNLSFGLNTVQGLSKDTDIKLDVHLMIQNPENYVEQFVKAG
ASIVGVHVESTQHIARAIQIIKNAGARAEVVVNPGTPLTELEELLPEIDQVLIMSVNPGFGGQKFLESSISKVKRLSALR
QARGLEFDIEIDGGISDKNIKAVYDAGVDVAVAGSYVFGAEDYTKQVQLLKELTK

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=217, Percent_Identity=37.3271889400922, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI219879828, Length=217, Percent_Identity=36.405529953917, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI24307923, Length=171, Percent_Identity=30.9941520467836, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI1789788, Length=216, Percent_Identity=41.2037037037037, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=33.6734693877551, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790754, Length=201, Percent_Identity=29.8507462686567, Blast_Score=111, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17552948, Length=208, Percent_Identity=38.9423076923077, Blast_Score=146, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=40.174672489083, Blast_Score=167, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24586301, Length=214, Percent_Identity=41.588785046729, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23177; Mature: 23177

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVAPSILSADPANLMGDINKVEGADYLHVDVMDGSFVPNLSFGLNTVQGLSKDTDIKL
CEEECCHHHCCCHHHHHHCCHHCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEE
DVHLMIQNPENYVEQFVKAGASIVGVHVESTQHIARAIQIIKNAGARAEVVVNPGTPLTE
EEEEEEECCHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
LEELLPEIDQVLIMSVNPGFGGQKFLESSISKVKRLSALRQARGLEFDIEIDGGISDKNI
HHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
KAVYDAGVDVAVAGSYVFGAEDYTKQVQLLKELTK
EEEEECCCCEEEECCEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKVAPSILSADPANLMGDINKVEGADYLHVDVMDGSFVPNLSFGLNTVQGLSKDTDIKL
CEEECCHHHCCCHHHHHHCCHHCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEE
DVHLMIQNPENYVEQFVKAGASIVGVHVESTQHIARAIQIIKNAGARAEVVVNPGTPLTE
EEEEEEECCHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHH
LEELLPEIDQVLIMSVNPGFGGQKFLESSISKVKRLSALRQARGLEFDIEIDGGISDKNI
HHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
KAVYDAGVDVAVAGSYVFGAEDYTKQVQLLKELTK
EEEEECCCCEEEECCEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]