Click here to switch to the map view.

The map label for this gene is efp2 [H]

Identifier: 116492581

GI number: 116492581

Start: 821714

End: 822277

Strand: Direct

Name: efp2 [H]

Synonym: PEPE_0814

Alternate gene names: 116492581

Gene position: 821714-822277 (Clockwise)

Preceding gene: 116492580

Following gene: 116492582

Centisome position: 44.84

GC content: 35.64

Gene sequence:

>564_bases
ATGAGTACAATTTCAACATCTGATTTTAAAAATGGTTTGACCATTGAATTTGATGATAATATTTGGCGCATTGTTGAATT
TCAACATGTTAAGCCGGGTAAAGGTAGTGCCTTTGTGCGTACTAAGTTGAAGAACTTAAGAAATGGCGCTGTTCAAGAAA
AAACTTTCCGTGCCGGCGAAAAAATGGAACAAGCTAATATTGAGACAAAACGTATGCAATATCTATATAATGATGGTGCT
AACTACGTTTTCATGGATAACAATACGTATGAACAAGTTGAAATTCCTAATGAACGTCTTGAAGAAGAGAAAAATTATTT
AGTTGAGAACATGGAAGTAAGTATCGCATTCTTTGGTACTGAAACACTTGGTGTTGAAGTGCCTAAGAATATTACTTTAA
AAGTTACTGCTACAGAACCTGGTATTAAAGGTAATACTGCTAGTGGTGGCTCAAAACCAGCTACAATGGAAACTGGTCTG
GTGGTTCAAGTTCCTTTCTTCGTTAATGAGGGAGATGCTCTTAACATCAATACTCAAGATGGTACTTATATTTCACGCGC
TTAA

Upstream 100 bases:

>100_bases
CGGGACAATAACTTTGTTCCGGCCTTTTTTAATGATTTTCTTGTTAAAAAGAGAATCGATTGATATCATTAGTTCTAGAA
TTAATTGGAGGAATCTTTTT

Downstream 100 bases:

>100_bases
TTTTTGGAGGCAATATAATGGCAGATACGAAATACTTGGAGTTAAGTAATTCTAGTTCAAAGAGTGGCGGGATTGCGATA
GCACCTGATGTTATTGAATC

Product: translation elongation factor P (EF-P)

Products: NA

Alternate protein names: EF-P 2 [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSTISTSDFKNGLTIEFDDNIWRIVEFQHVKPGKGSAFVRTKLKNLRNGAVQEKTFRAGEKMEQANIETKRMQYLYNDGA
NYVFMDNNTYEQVEIPNERLEEEKNYLVENMEVSIAFFGTETLGVEVPKNITLKVTATEPGIKGNTASGGSKPATMETGL
VVQVPFFVNEGDALNINTQDGTYISRA

Sequences:

>Translated_187_residues
MSTISTSDFKNGLTIEFDDNIWRIVEFQHVKPGKGSAFVRTKLKNLRNGAVQEKTFRAGEKMEQANIETKRMQYLYNDGA
NYVFMDNNTYEQVEIPNERLEEEKNYLVENMEVSIAFFGTETLGVEVPKNITLKVTATEPGIKGNTASGGSKPATMETGL
VVQVPFFVNEGDALNINTQDGTYISRA
>Mature_186_residues
STISTSDFKNGLTIEFDDNIWRIVEFQHVKPGKGSAFVRTKLKNLRNGAVQEKTFRAGEKMEQANIETKRMQYLYNDGAN
YVFMDNNTYEQVEIPNERLEEEKNYLVENMEVSIAFFGTETLGVEVPKNITLKVTATEPGIKGNTASGGSKPATMETGLV
VQVPFFVNEGDALNINTQDGTYISRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=186, Percent_Identity=37.6344086021505, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=27.1739130434783, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20934; Mature: 20803

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISTSDFKNGLTIEFDDNIWRIVEFQHVKPGKGSAFVRTKLKNLRNGAVQEKTFRAGE
CCCCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHCC
KMEQANIETKRMQYLYNDGANYVFMDNNTYEQVEIPNERLEEEKNYLVENMEVSIAFFGT
HHHHCCCHHHHEEEEEECCCCEEEECCCCEEEEECCHHHHHHHHHHEEECEEEEEEEEEC
ETLGVEVPKNITLKVTATEPGIKGNTASGGSKPATMETGLVVQVPFFVNEGDALNINTQD
EEECEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEEEEEEECCCCEEEEECCC
GTYISRA
CEEEECC
>Mature Secondary Structure 
STISTSDFKNGLTIEFDDNIWRIVEFQHVKPGKGSAFVRTKLKNLRNGAVQEKTFRAGE
CCCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHCC
KMEQANIETKRMQYLYNDGANYVFMDNNTYEQVEIPNERLEEEKNYLVENMEVSIAFFGT
HHHHCCCHHHHEEEEEECCCCEEEECCCCEEEEECCHHHHHHHHHHEEECEEEEEEEEEC
ETLGVEVPKNITLKVTATEPGIKGNTASGGSKPATMETGLVVQVPFFVNEGDALNINTQD
EEECEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEEEEEEECCCCEEEEECCC
GTYISRA
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA