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The map label for this gene is steT [H]

Identifier: 116492379

GI number: 116492379

Start: 640240

End: 641562

Strand: Reverse

Name: steT [H]

Synonym: PEPE_0584

Alternate gene names: 116492379

Gene position: 641562-640240 (Counterclockwise)

Preceding gene: 116492380

Following gene: 116492378

Centisome position: 35.01

GC content: 43.92

Gene sequence:

>1323_bases
ATGAATAAAAACGAACATACTCACCTGCAAAAGAACATCGGGCTCTTTGCAGCCTTTTCGACCGTGATGGGGACGGTAAT
TGGAGCGGGAGTCTTTTTCAAAGTTTCTAGTGTAACAGCTAGTACGCAATCAGCAGGATTAAGCCTGTTAGCTTGGCTAG
CTGGTGGTCTACTAACGATTTGTGCCGGACTGACCAGTGCCGAATTAGCTTCGGCGATTCCGGTCACCGGTGGCGCCATT
AAATATCTCGAAGTCACTTATGGGAAACTAACTGGTTTTCTATTAGGCTGGGCACAGACCTTAATTTACTTCCCCGCTAA
CATCGCTGCTCTTTCCATTATTTTTGGAACGCAATTTACCAACCTCTTTCATTTGAAAGCTGGACTAATCTTATCAATTG
CGGTCATCTGTGGGGCCTCAATTACAGGAATTAATTTACTAGGTACCAAGCACGGTGCACGTCTCCAATCAGTGGCCTTG
ATTGCCAAGTTAATCCCGATCGCGGTGATTATTGCCTTCGGGCTTTTTGCTCCAAGCAATGTCCATCTTAGCTTGATTCC
GGAGCATTTTACGACTTCTCAAACTTTGACTGGTTTTAGTGGCGGATTATTATCAACCCTTTTTGCCTATGATGGTTGGT
TAGGAATTGGCGCGATTGCTGGAGAAATGAAGAATCCTAAACGAGACTTGCCCCTTGCGATTGGTTTGGGACTAACTGGA
ATCATGATCGTCTACCTTGGCATTAACCTAGTCTTTTTGAAGACCCTCCCAATCAGCGATTTAGCGGGCAATCTAAATGC
AGCTTCTACCGCTGCGGGACAGCTCTTTGGTAACATCGGTGGAAAACTAGTGACCATTGGAATCTTAATCTCCGTTTATG
GAGCTTTGAATGGTTATACGATGACCGGAATGCGCATCCCCTACGCCATGGCTAAAGAAGATTCTCTGCCAATGAGTAAT
CATCTAAGTAAATTATCACGCACAGCGGTCCCTTACGTGGCTGGAATCGTCCAATTAGTAATCGCTGGACTAATGATGAT
TGTTGGTTCCTTTGACCTGTTGACCGACATGTTAATCTTTGTCATGTGGATCTTTAACGTTTTGATTTTCTATGCAGTCA
TTAAACTACGTCACACGCAACCAGATTTAGTACGACCATATAAAGTCCCCCTCTATCCATTTTTACCAGTGGTTGCCATT
CTGGGAGGAATTTTCGTCTTAGTCACGACGATTATCGACCAACCAATATTAGCCACCACCGGAATAGTTATAACTTTATT
AGGAATTCCACTTTACCTTGTAACCAAGCGCAAATCATCATAA

Upstream 100 bases:

>100_bases
CCAGCTAGAAAGGTGATTTATTTGTTAGATAATTACCACTCCTGAGCAAAATTATTTATAATAGTAAAATAAGTCTTAAA
GCATACAGAGGAAAGAATTT

Downstream 100 bases:

>100_bases
GATAGATGGTAAATCTTTAAGGAGGAGACTACTTATGTTCGTAATTAAATATCTACCGTTTCTCGGTCTCTCCCTGTTGA
TCGTGATTGGTTGTTTAGTG

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNKNEHTHLQKNIGLFAAFSTVMGTVIGAGVFFKVSSVTASTQSAGLSLLAWLAGGLLTICAGLTSAELASAIPVTGGAI
KYLEVTYGKLTGFLLGWAQTLIYFPANIAALSIIFGTQFTNLFHLKAGLILSIAVICGASITGINLLGTKHGARLQSVAL
IAKLIPIAVIIAFGLFAPSNVHLSLIPEHFTTSQTLTGFSGGLLSTLFAYDGWLGIGAIAGEMKNPKRDLPLAIGLGLTG
IMIVYLGINLVFLKTLPISDLAGNLNAASTAAGQLFGNIGGKLVTIGILISVYGALNGYTMTGMRIPYAMAKEDSLPMSN
HLSKLSRTAVPYVAGIVQLVIAGLMMIVGSFDLLTDMLIFVMWIFNVLIFYAVIKLRHTQPDLVRPYKVPLYPFLPVVAI
LGGIFVLVTTIIDQPILATTGIVITLLGIPLYLVTKRKSS

Sequences:

>Translated_440_residues
MNKNEHTHLQKNIGLFAAFSTVMGTVIGAGVFFKVSSVTASTQSAGLSLLAWLAGGLLTICAGLTSAELASAIPVTGGAI
KYLEVTYGKLTGFLLGWAQTLIYFPANIAALSIIFGTQFTNLFHLKAGLILSIAVICGASITGINLLGTKHGARLQSVAL
IAKLIPIAVIIAFGLFAPSNVHLSLIPEHFTTSQTLTGFSGGLLSTLFAYDGWLGIGAIAGEMKNPKRDLPLAIGLGLTG
IMIVYLGINLVFLKTLPISDLAGNLNAASTAAGQLFGNIGGKLVTIGILISVYGALNGYTMTGMRIPYAMAKEDSLPMSN
HLSKLSRTAVPYVAGIVQLVIAGLMMIVGSFDLLTDMLIFVMWIFNVLIFYAVIKLRHTQPDLVRPYKVPLYPFLPVVAI
LGGIFVLVTTIIDQPILATTGIVITLLGIPLYLVTKRKSS
>Mature_440_residues
MNKNEHTHLQKNIGLFAAFSTVMGTVIGAGVFFKVSSVTASTQSAGLSLLAWLAGGLLTICAGLTSAELASAIPVTGGAI
KYLEVTYGKLTGFLLGWAQTLIYFPANIAALSIIFGTQFTNLFHLKAGLILSIAVICGASITGINLLGTKHGARLQSVAL
IAKLIPIAVIIAFGLFAPSNVHLSLIPEHFTTSQTLTGFSGGLLSTLFAYDGWLGIGAIAGEMKNPKRDLPLAIGLGLTG
IMIVYLGINLVFLKTLPISDLAGNLNAASTAAGQLFGNIGGKLVTIGILISVYGALNGYTMTGMRIPYAMAKEDSLPMSN
HLSKLSRTAVPYVAGIVQLVIAGLMMIVGSFDLLTDMLIFVMWIFNVLIFYAVIKLRHTQPDLVRPYKVPLYPFLPVVAI
LGGIFVLVTTIIDQPILATTGIVITLLGIPLYLVTKRKSS

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=446, Percent_Identity=28.9237668161435, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI115648022, Length=446, Percent_Identity=28.9237668161435, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI187423910, Length=421, Percent_Identity=29.9287410926366, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI7657591, Length=421, Percent_Identity=29.9287410926366, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI186910308, Length=446, Percent_Identity=29.1479820627803, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI186910306, Length=446, Percent_Identity=29.1479820627803, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI186910304, Length=446, Percent_Identity=29.1479820627803, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI33286428, Length=435, Percent_Identity=27.3563218390805, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI7657683, Length=435, Percent_Identity=29.6551724137931, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI71979932, Length=452, Percent_Identity=29.4247787610619, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI9790235, Length=441, Percent_Identity=28.3446712018141, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI71999149, Length=454, Percent_Identity=22.9074889867841, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33286430, Length=227, Percent_Identity=25.9911894273128, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4507047, Length=423, Percent_Identity=26.4775413711584, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI258614005, Length=425, Percent_Identity=24, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=23.7647058823529, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=24, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082250, Length=457, Percent_Identity=26.9146608315098, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081708, Length=457, Percent_Identity=22.5382932166302, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367353, Length=357, Percent_Identity=24.3697478991597, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786302, Length=448, Percent_Identity=22.3214285714286, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786694, Length=390, Percent_Identity=24.8717948717949, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787890, Length=331, Percent_Identity=27.190332326284, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789017, Length=323, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=433, Percent_Identity=26.7898383371824, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71982612, Length=455, Percent_Identity=26.3736263736264, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71982608, Length=455, Percent_Identity=26.3736263736264, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17568033, Length=456, Percent_Identity=26.0964912280702, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI32566699, Length=421, Percent_Identity=27.5534441805226, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71995388, Length=454, Percent_Identity=25.7709251101322, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71995382, Length=454, Percent_Identity=25.7709251101322, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71993915, Length=446, Percent_Identity=27.3542600896861, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566695, Length=427, Percent_Identity=25.0585480093677, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193208714, Length=427, Percent_Identity=25.0585480093677, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71990446, Length=459, Percent_Identity=25.7080610021786, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982623, Length=270, Percent_Identity=26.2962962962963, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321492, Length=353, Percent_Identity=24.6458923512748, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321751, Length=362, Percent_Identity=24.3093922651934, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45550968, Length=444, Percent_Identity=27.9279279279279, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI19921172, Length=444, Percent_Identity=27.9279279279279, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24651635, Length=436, Percent_Identity=27.9816513761468, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24651633, Length=436, Percent_Identity=27.9816513761468, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21357367, Length=440, Percent_Identity=27.9545454545455, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24641993, Length=398, Percent_Identity=28.894472361809, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24641995, Length=398, Percent_Identity=28.894472361809, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI221331183, Length=454, Percent_Identity=25.9911894273128, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17647653, Length=454, Percent_Identity=25.9911894273128, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24664379, Length=454, Percent_Identity=25.9911894273128, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24666159, Length=419, Percent_Identity=23.1503579952267, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221512776, Length=419, Percent_Identity=23.1503579952267, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 46438; Mature: 46438

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNEHTHLQKNIGLFAAFSTVMGTVIGAGVFFKVSSVTASTQSAGLSLLAWLAGGLLTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHCCHHHHHHHHHHHHHHHHHHH
CAGLTSAELASAIPVTGGAIKYLEVTYGKLTGFLLGWAQTLIYFPANIAALSIIFGTQFT
HHCCCHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NLFHLKAGLILSIAVICGASITGINLLGTKHGARLQSVALIAKLIPIAVIIAFGLFAPSN
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VHLSLIPEHFTTSQTLTGFSGGLLSTLFAYDGWLGIGAIAGEMKNPKRDLPLAIGLGLTG
CEEEECCCHHCCCCHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEHHHHHH
IMIVYLGINLVFLKTLPISDLAGNLNAASTAAGQLFGNIGGKLVTIGILISVYGALNGYT
HHHHHHHHHHEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEE
MTGMRIPYAMAKEDSLPMSNHLSKLSRTAVPYVAGIVQLVIAGLMMIVGSFDLLTDMLIF
EECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VMWIFNVLIFYAVIKLRHTQPDLVRPYKVPLYPFLPVVAILGGIFVLVTTIIDQPILATT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GIVITLLGIPLYLVTKRKSS
HHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MNKNEHTHLQKNIGLFAAFSTVMGTVIGAGVFFKVSSVTASTQSAGLSLLAWLAGGLLTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHCCHHHHHHHHHHHHHHHHHHH
CAGLTSAELASAIPVTGGAIKYLEVTYGKLTGFLLGWAQTLIYFPANIAALSIIFGTQFT
HHCCCHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NLFHLKAGLILSIAVICGASITGINLLGTKHGARLQSVALIAKLIPIAVIIAFGLFAPSN
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VHLSLIPEHFTTSQTLTGFSGGLLSTLFAYDGWLGIGAIAGEMKNPKRDLPLAIGLGLTG
CEEEECCCHHCCCCHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEHHHHHH
IMIVYLGINLVFLKTLPISDLAGNLNAASTAAGQLFGNIGGKLVTIGILISVYGALNGYT
HHHHHHHHHHEEEECCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEE
MTGMRIPYAMAKEDSLPMSNHLSKLSRTAVPYVAGIVQLVIAGLMMIVGSFDLLTDMLIF
EECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VMWIFNVLIFYAVIKLRHTQPDLVRPYKVPLYPFLPVVAILGGIFVLVTTIIDQPILATT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GIVITLLGIPLYLVTKRKSS
HHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]