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The map label for this gene is csd [H]

Identifier: 116492289

GI number: 116492289

Start: 541831

End: 543006

Strand: Direct

Name: csd [H]

Synonym: PEPE_0488

Alternate gene names: 116492289

Gene position: 541831-543006 (Clockwise)

Preceding gene: 116492288

Following gene: 116492290

Centisome position: 29.57

GC content: 42.77

Gene sequence:

>1176_bases
ATGATAGATGATCAAAAAATAGCCTATTTAGATAATGCAGCGACCATGCCGATGCCAGACGAAGTATTGGAAGTAATTGA
TATGTACTACCATGCCCATAAAGTTAATGTGCATCGGGGAATGTATCGATTAGCTCACCAAGTTACGGAACAATATGAAG
CAGTTCGTCAAGCCACGGCTGATTTTATCAATGCTCAGGACTCCTCGGAGATTATTTTTACCAGTGGTACGACCGATGCC
CTAAATTTAGTTGCTTTTGGTTATGCGGAAAAACAACTTCAACCAGACGATGAAATTATTATCAGTGTTTTAGAACACCA
TTCGAACTTCATTCCGTGGCAACGCGTGGCTCATAAAACGGGCGCAAAATTGAAAATTGTCGGTTTAGATGACCAACAGA
ATTTAGATATGCAGCAATTTTCCGAATTGCTTACGGAGAAAACCAAGCTAGTCGCCATTACGTTAGTTTCTAATGTGCTA
GGAAGCATTGTGGATGCCAAGCAAATTATTGAACAAACGCATCATATGGGGGGAGTGGTTGTATTAGATGCTGCTCAAGC
AGTTGGTCATCTACCCCTAGATGTTCAAAAATTAGATGCTGATTTCTTAGCCTTTTCTGGACATAAAATGTATGGGCCTA
CCGGAGTTGGAGTTTTATATGGAAAACGGAACTTGTTAGAACAGGTTGCGCCTTTGCGATTTGGCGGGGAAATGGCTGAT
GAAGTTGATGCTCAAACGGCGACGTTTCAACCGCTCCCCCTACGGCTAGAAGCCGGTACGCCTAACATTGCCGGAGTTTT
AGGGTTGGGGGCTGCTATTCAATATCTACAAAAGATTGGTTTTACAACCATTCATCAACATGAACAGCAATTATTAAATC
AGTTATACCAAGGATTACGGCAGATACCAGCAATTAAAGTTTATGGTCCAAGGTCTGCGGCCGAGCGCCAAGGGGTGCTT
AGTTTTAACTATGGAACTATTCATGCCCATGATGTAGCGACCATTATTGATACCGAAAATGTAGCGGTTAGAGCCGGACA
TATGTGTGCGGAACCTTTAATGCAAGCTCTAGGAGTAAGTAGCGTCGTCCGGGCCAGTGTTTCGTATATGAACACGACGA
GGGATGTCGAACAGCTTTTAGCAGCAATGAATCAGGTGGGTCAAATTTTATTATGA

Upstream 100 bases:

>100_bases
TCGGGGATTAGTGGAGGCGGATGCTAAACAAATTTTAATCAATAATTTCATGGAACCTGTTTTACCAAAAGAAACTGTGG
AAAAGTAATGGTGGTAAACA

Downstream 100 bases:

>100_bases
GTAATATTCAAGAACTTTATCAAAAAATAATTGTAAATCATGCTAAGTATCCGATCGGAGTCGGAGTTTTACCGCAATAT
AATTACCACGCTAAATTGAA

Product: cysteine sulfinate desulfinase/cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MIDDQKIAYLDNAATMPMPDEVLEVIDMYYHAHKVNVHRGMYRLAHQVTEQYEAVRQATADFINAQDSSEIIFTSGTTDA
LNLVAFGYAEKQLQPDDEIIISVLEHHSNFIPWQRVAHKTGAKLKIVGLDDQQNLDMQQFSELLTEKTKLVAITLVSNVL
GSIVDAKQIIEQTHHMGGVVVLDAAQAVGHLPLDVQKLDADFLAFSGHKMYGPTGVGVLYGKRNLLEQVAPLRFGGEMAD
EVDAQTATFQPLPLRLEAGTPNIAGVLGLGAAIQYLQKIGFTTIHQHEQQLLNQLYQGLRQIPAIKVYGPRSAAERQGVL
SFNYGTIHAHDVATIIDTENVAVRAGHMCAEPLMQALGVSSVVRASVSYMNTTRDVEQLLAAMNQVGQILL

Sequences:

>Translated_391_residues
MIDDQKIAYLDNAATMPMPDEVLEVIDMYYHAHKVNVHRGMYRLAHQVTEQYEAVRQATADFINAQDSSEIIFTSGTTDA
LNLVAFGYAEKQLQPDDEIIISVLEHHSNFIPWQRVAHKTGAKLKIVGLDDQQNLDMQQFSELLTEKTKLVAITLVSNVL
GSIVDAKQIIEQTHHMGGVVVLDAAQAVGHLPLDVQKLDADFLAFSGHKMYGPTGVGVLYGKRNLLEQVAPLRFGGEMAD
EVDAQTATFQPLPLRLEAGTPNIAGVLGLGAAIQYLQKIGFTTIHQHEQQLLNQLYQGLRQIPAIKVYGPRSAAERQGVL
SFNYGTIHAHDVATIIDTENVAVRAGHMCAEPLMQALGVSSVVRASVSYMNTTRDVEQLLAAMNQVGQILL
>Mature_391_residues
MIDDQKIAYLDNAATMPMPDEVLEVIDMYYHAHKVNVHRGMYRLAHQVTEQYEAVRQATADFINAQDSSEIIFTSGTTDA
LNLVAFGYAEKQLQPDDEIIISVLEHHSNFIPWQRVAHKTGAKLKIVGLDDQQNLDMQQFSELLTEKTKLVAITLVSNVL
GSIVDAKQIIEQTHHMGGVVVLDAAQAVGHLPLDVQKLDADFLAFSGHKMYGPTGVGVLYGKRNLLEQVAPLRFGGEMAD
EVDAQTATFQPLPLRLEAGTPNIAGVLGLGAAIQYLQKIGFTTIHQHEQQLLNQLYQGLRQIPAIKVYGPRSAAERQGVL
SFNYGTIHAHDVATIIDTENVAVRAGHMCAEPLMQALGVSSVVRASVSYMNTTRDVEQLLAAMNQVGQILL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=386, Percent_Identity=26.6839378238342, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI156713448, Length=312, Percent_Identity=27.5641025641026, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1787970, Length=390, Percent_Identity=40.7692307692308, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1789175, Length=383, Percent_Identity=40.9921671018277, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI48994898, Length=385, Percent_Identity=27.7922077922078, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI25143064, Length=359, Percent_Identity=28.4122562674095, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193211090, Length=382, Percent_Identity=27.7486910994764, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17533177, Length=340, Percent_Identity=24.4117647058824, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319831, Length=394, Percent_Identity=27.1573604060914, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI20129463, Length=383, Percent_Identity=27.4151436031332, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42943; Mature: 42943

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDQKIAYLDNAATMPMPDEVLEVIDMYYHAHKVNVHRGMYRLAHQVTEQYEAVRQATA
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFINAQDSSEIIFTSGTTDALNLVAFGYAEKQLQPDDEIIISVLEHHSNFIPWQRVAHKT
HHHCCCCCCCEEEECCCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHC
GAKLKIVGLDDQQNLDMQQFSELLTEKTKLVAITLVSNVLGSIVDAKQIIEQTHHMGGVV
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VLDAAQAVGHLPLDVQKLDADFLAFSGHKMYGPTGVGVLYGKRNLLEQVAPLRFGGEMAD
EEECHHHHCCCCCCHHHHCCHHHEECCCEEECCCCCEEEECCHHHHHHHHCHHCCCCHHH
EVDAQTATFQPLPLRLEAGTPNIAGVLGLGAAIQYLQKIGFTTIHQHEQQLLNQLYQGLR
HHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QIPAIKVYGPRSAAERQGVLSFNYGTIHAHDVATIIDTENVAVRAGHMCAEPLMQALGVS
HCCEEEEECCCCHHHCCCCEEECCCEEECCCEEEEEECCCCEEECCHHHHHHHHHHHCHH
SVVRASVSYMNTTRDVEQLLAAMNQVGQILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDDQKIAYLDNAATMPMPDEVLEVIDMYYHAHKVNVHRGMYRLAHQVTEQYEAVRQATA
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFINAQDSSEIIFTSGTTDALNLVAFGYAEKQLQPDDEIIISVLEHHSNFIPWQRVAHKT
HHHCCCCCCCEEEECCCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHC
GAKLKIVGLDDQQNLDMQQFSELLTEKTKLVAITLVSNVLGSIVDAKQIIEQTHHMGGVV
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VLDAAQAVGHLPLDVQKLDADFLAFSGHKMYGPTGVGVLYGKRNLLEQVAPLRFGGEMAD
EEECHHHHCCCCCCHHHHCCHHHEECCCEEECCCCCEEEECCHHHHHHHHCHHCCCCHHH
EVDAQTATFQPLPLRLEAGTPNIAGVLGLGAAIQYLQKIGFTTIHQHEQQLLNQLYQGLR
HHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QIPAIKVYGPRSAAERQGVLSFNYGTIHAHDVATIIDTENVAVRAGHMCAEPLMQALGVS
HCCEEEEECCCCHHHCCCCEEECCCEEECCCEEEEEECCCCEEECCHHHHHHHHHHHCHH
SVVRASVSYMNTTRDVEQLLAAMNQVGQILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA