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The map label for this gene is gpmA [H]

Identifier: 116492206

GI number: 116492206

Start: 449020

End: 449688

Strand: Reverse

Name: gpmA [H]

Synonym: PEPE_0403

Alternate gene names: 116492206

Gene position: 449688-449020 (Counterclockwise)

Preceding gene: 116492211

Following gene: 116492205

Centisome position: 24.54

GC content: 42.6

Gene sequence:

>669_bases
ATGAAAAAATTAAAACTATATTTTGTTCGTCATGGACAAACTATTTTCAACAAATATAACCGAATGCAAGGTTGGTCAGA
CTCCCCGTTAACCGAAAAGGGCTATGCTGATGCACATCGGGCCGGAGCTCGTTTGAAAAACATTGCATTTGATGCGGCTT
ATGCCTCCGATACTACCCGCGCAATGAATACCGCCAACGCCATTATGGCTGAAAATGCGCATGAACAATTACCAATCGAA
ACTATGCCAGAATTCCGCGAAGAATTCTACGGCTATTACGAAGGTAGTGATTCTGCCCAAGCTTGGTTCGAAGCTTTAAT
GCCAGTTTCAGGCAAACGAACTTTCCATGAATTTTTGGAAGAAAACCCGATTGCTGCTTCAAAAGATGCGATGAAAGCAG
CCGACCCTTTCCATGATGCGGAAAATGATGCAGAATTCTGGGATCGTCTCAATCGTGGCTTTGCCCAATTGATGGAAACC
CATAACGATGGAGACACCATTTTAGTGGTCAGTCATGGAACTACAATTCGTTCAATGGCAGGAAAAGCTGATCCAACACT
AGATATTACTTGGGGTCCTCAAAACGGTAGTATTAATCGTTTTACTTTAGACGATGATGGCCTTCATCTCGATGAATACA
ACAATCATGGAGACGAAGAGCTTTTGTAA

Upstream 100 bases:

>100_bases
CCTTTTTATGCGTTTTCACAAAGATTTAGCTAATTTGGTACACGGGATATATGATAGAATGATTTAGGTTTTACAAAAAA
TAAGTGAGGAAAGGATTTTT

Downstream 100 bases:

>100_bases
ACAAATTTTAGGAGAGATAAAAGAATGGATAATTCACCTTTAGATTCAAAAAAAAGGTATATTAGTTGGCCTGTAGTAGC
CTTAATGGACTTTGTAACGG

Product: fructose-2,6-bisphosphatase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKKLKLYFVRHGQTIFNKYNRMQGWSDSPLTEKGYADAHRAGARLKNIAFDAAYASDTTRAMNTANAIMAENAHEQLPIE
TMPEFREEFYGYYEGSDSAQAWFEALMPVSGKRTFHEFLEENPIAASKDAMKAADPFHDAENDAEFWDRLNRGFAQLMET
HNDGDTILVVSHGTTIRSMAGKADPTLDITWGPQNGSINRFTLDDDGLHLDEYNNHGDEELL

Sequences:

>Translated_222_residues
MKKLKLYFVRHGQTIFNKYNRMQGWSDSPLTEKGYADAHRAGARLKNIAFDAAYASDTTRAMNTANAIMAENAHEQLPIE
TMPEFREEFYGYYEGSDSAQAWFEALMPVSGKRTFHEFLEENPIAASKDAMKAADPFHDAENDAEFWDRLNRGFAQLMET
HNDGDTILVVSHGTTIRSMAGKADPTLDITWGPQNGSINRFTLDDDGLHLDEYNNHGDEELL
>Mature_222_residues
MKKLKLYFVRHGQTIFNKYNRMQGWSDSPLTEKGYADAHRAGARLKNIAFDAAYASDTTRAMNTANAIMAENAHEQLPIE
TMPEFREEFYGYYEGSDSAQAWFEALMPVSGKRTFHEFLEENPIAASKDAMKAADPFHDAENDAEFWDRLNRGFAQLMET
HNDGDTILVVSHGTTIRSMAGKADPTLDITWGPQNGSINRFTLDDDGLHLDEYNNHGDEELL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4502445, Length=102, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40353764, Length=102, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786970, Length=102, Percent_Identity=39.2156862745098, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786857, Length=179, Percent_Identity=26.8156424581006, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322697, Length=193, Percent_Identity=28.4974093264249, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646216, Length=201, Percent_Identity=26.3681592039801, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85725270, Length=204, Percent_Identity=25.9803921568627, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725272, Length=204, Percent_Identity=25.9803921568627, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650981, Length=204, Percent_Identity=25.9803921568627, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 25119; Mature: 25119

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKLYFVRHGQTIFNKYNRMQGWSDSPLTEKGYADAHRAGARLKNIAFDAAYASDTTR
CCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
AMNTANAIMAENAHEQLPIETMPEFREEFYGYYEGSDSAQAWFEALMPVSGKRTFHEFLE
HHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
ENPIAASKDAMKAADPFHDAENDAEFWDRLNRGFAQLMETHNDGDTILVVSHGTTIRSMA
CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHC
GKADPTLDITWGPQNGSINRFTLDDDGLHLDEYNNHGDEELL
CCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLKLYFVRHGQTIFNKYNRMQGWSDSPLTEKGYADAHRAGARLKNIAFDAAYASDTTR
CCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
AMNTANAIMAENAHEQLPIETMPEFREEFYGYYEGSDSAQAWFEALMPVSGKRTFHEFLE
HHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
ENPIAASKDAMKAADPFHDAENDAEFWDRLNRGFAQLMETHNDGDTILVVSHGTTIRSMA
CCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHC
GKADPTLDITWGPQNGSINRFTLDDDGLHLDEYNNHGDEELL
CCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA