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The map label for this gene is ltaS1 [H]

Identifier: 116492170

GI number: 116492170

Start: 413239

End: 415395

Strand: Reverse

Name: ltaS1 [H]

Synonym: PEPE_0367

Alternate gene names: 116492170

Gene position: 415395-413239 (Counterclockwise)

Preceding gene: 116492174

Following gene: 116492168

Centisome position: 22.67

GC content: 35.14

Gene sequence:

>2157_bases
ATGAAATCTTTAAAATCAAAAATTGATACTAGATTCGGATTCTTTATCCTTATTACTATTTTATTTTGGGCGAAGACTCT
GTTTGCATATCTAGCTGATATTTCACTAGGTGTAGGTAGTATCTTTCAATGGATAATTCTTTTAATTAATCCAGTTGCTA
CAACCGTCCTCATCTTTGGACTTGCATTATATATTCGACCGAAAAAAATTTTTTATTGGGTAGCGATGTTGTTGGATGTC
GCCAATACCGTCATGCTCTATCTCAATGTCATCTACTTTAGAGAATTTTCTGACTTTATGACCGTTAATACTATGTTGGG
CTATTCCAAGGTTAATCAAGGCTTAAGTGCTAGCTCAATGTCCTTAACTAATGTTCATGATATTTTCTACTGGTTAGATA
TCATCGTTATTTTCTTATTACTCGTTCTGAAGAAAATAAAAATGGACCCCCATCCTTTACCTAAAAAGTTTGGGTTTCAA
ATCACCTCACTGGGCTTTTTATTTTTTGCATTTAATCTAATGCTCGCGGAAATGGATCGCCCGCAGTTAATTACCAGAAC
TTTTGATCGTTCTTATATTGTTAAATACATGGGGCTCGATGCCTTTACTGCTTATGATGGTGTCCAACTTGAACGTAACC
ATAAAATGCGTTCTGAAGCTAAGAAAAGCGAATTAACTTCAATTGAAAAATATGTTAAGCATCATTATGCCAAACCGTCG
AATGTTACTTTTGCCAAGGCTAAGGGAAAAAATGTTATTATCATTCACCTAGAAAGTTTTCAACAATTCTTAATCGATGA
TAAAGTGGAAGGCCAAACAGTAACACCATTCCTAAACAGCATTTACCACAGTAAATCAACTTACTCATTTAGTAACTTTT
TCCATCAAGTTGGTCAAGGTAAAACTAGTGATGCTGAAAATATGCTTGAAACTGGCACGTTTGGGACAGCTCAAGGTTCA
CTGTTCGCCCAGTTAGGATCTGATCAAACCTTCCAAGCTGCTCCAGCAATTTTAAAACAACATGGAAACTACACTTCTGC
GGTTTTCCACGGTAATACTGCTTCATTTTGGAATCGTAATAGCACTTATAAAAATATGGGTTATGAGAACTTCTTCTCTG
CCAGTGATTTTGATGTTTCTGGGGATAAATCTACTACCTATGGTCTAAAAGATAAGCTTCTCTTCAAAGATTCAATTAAG
TACCTTCAACACTTACAGCAGCCGTTTTATGCTAAATACATCACTGTAAGTAACCACATCCCATACACTTTAGATGATGA
GGATAGTACTTTTAAAACGCCTAGTACTGGCGATAAAACTGTAGACAACTACTTCAAAACTGCTAATTACTTAGATCAAT
CTGTTGAAGAATTCTTTAATTTCTTAAAGAAATCCGGTTTGTATGATGATTCGATGATTGTTTTATACGGTGATCATTAT
GGAATTTCCAATTCCTCTAATACAGCACTAGCTAAAACTTTTGAACAAGATCCGGATCATTTTAAAGAATTCGGCTCTAA
TCCAACTGAAAATTGGAATAATTGGGATAATTCACAGCTCCAACGAGTCCCATTAATGATTCACATTCCAGGTATGAAAG
ATGGTGGCATTCAATCCCAATATGGTGGTGAAATTGATGTTCTACCAACGATCTTGCATTTATTAGGAATCTCAACCAAA
AACTATATCCAATTTGGTACTGACCTGTTGTCTAAGCAACATGACCAAGTGGTTGCTTTTAGAAATAACGATTATGTAAC
ACCAACCTATAGTTCTATCGGTGGTAAACTTTATGACAGTTCCGGCAATGAGATTACCGATCCTAACACCACTTTTAAAA
AGAAAGTTGAAAAAGATCGTAAAGCTGCTAAAGAACAATTAGCGATGTCAGATTCGTTAAATGAAAAGAATCTCCTCCGT
TTCTATAAGAATCCGGACTTTAAAAAGGTTAATTCAGCTAACTACAATTATTCGGATGGTTTAACGAAAGCCATCAAGCT
AGAAGATAAATTAGGCTTAAAATCGACTTCTATGTTCTCCAAGAATCAAGATAAATCACTTGAAGATTTGTACAAAACTA
ATGCTCCTGAAGCAAACCACAAATCAACTAGTGAAAACCGAATTAAAATTACAAATCCAGATGCCAACGGCAGTTAA

Upstream 100 bases:

>100_bases
ATTCATCCCCCTTACCCAATAGTTAACCAAATCATTTAAAAAAATATGGTAAAATTGCATTTATGCATTAATCTTGTTCT
ATTTGAAAGGTCTTTAAAAA

Downstream 100 bases:

>100_bases
CAAAAATGCAGTGAACTTAGTTTTTAAGTTCACTGCATTTTTATATATTCAGATTATTTTTCAAACATGGATGTACTATG
AACAGGTCCACGTTTGCCTG

Product: phosphoglycerol transferase/alkaline phosphatase superfamily protein

Products: NA

Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MKSLKSKIDTRFGFFILITILFWAKTLFAYLADISLGVGSIFQWIILLINPVATTVLIFGLALYIRPKKIFYWVAMLLDV
ANTVMLYLNVIYFREFSDFMTVNTMLGYSKVNQGLSASSMSLTNVHDIFYWLDIIVIFLLLVLKKIKMDPHPLPKKFGFQ
ITSLGFLFFAFNLMLAEMDRPQLITRTFDRSYIVKYMGLDAFTAYDGVQLERNHKMRSEAKKSELTSIEKYVKHHYAKPS
NVTFAKAKGKNVIIIHLESFQQFLIDDKVEGQTVTPFLNSIYHSKSTYSFSNFFHQVGQGKTSDAENMLETGTFGTAQGS
LFAQLGSDQTFQAAPAILKQHGNYTSAVFHGNTASFWNRNSTYKNMGYENFFSASDFDVSGDKSTTYGLKDKLLFKDSIK
YLQHLQQPFYAKYITVSNHIPYTLDDEDSTFKTPSTGDKTVDNYFKTANYLDQSVEEFFNFLKKSGLYDDSMIVLYGDHY
GISNSSNTALAKTFEQDPDHFKEFGSNPTENWNNWDNSQLQRVPLMIHIPGMKDGGIQSQYGGEIDVLPTILHLLGISTK
NYIQFGTDLLSKQHDQVVAFRNNDYVTPTYSSIGGKLYDSSGNEITDPNTTFKKKVEKDRKAAKEQLAMSDSLNEKNLLR
FYKNPDFKKVNSANYNYSDGLTKAIKLEDKLGLKSTSMFSKNQDKSLEDLYKTNAPEANHKSTSENRIKITNPDANGS

Sequences:

>Translated_718_residues
MKSLKSKIDTRFGFFILITILFWAKTLFAYLADISLGVGSIFQWIILLINPVATTVLIFGLALYIRPKKIFYWVAMLLDV
ANTVMLYLNVIYFREFSDFMTVNTMLGYSKVNQGLSASSMSLTNVHDIFYWLDIIVIFLLLVLKKIKMDPHPLPKKFGFQ
ITSLGFLFFAFNLMLAEMDRPQLITRTFDRSYIVKYMGLDAFTAYDGVQLERNHKMRSEAKKSELTSIEKYVKHHYAKPS
NVTFAKAKGKNVIIIHLESFQQFLIDDKVEGQTVTPFLNSIYHSKSTYSFSNFFHQVGQGKTSDAENMLETGTFGTAQGS
LFAQLGSDQTFQAAPAILKQHGNYTSAVFHGNTASFWNRNSTYKNMGYENFFSASDFDVSGDKSTTYGLKDKLLFKDSIK
YLQHLQQPFYAKYITVSNHIPYTLDDEDSTFKTPSTGDKTVDNYFKTANYLDQSVEEFFNFLKKSGLYDDSMIVLYGDHY
GISNSSNTALAKTFEQDPDHFKEFGSNPTENWNNWDNSQLQRVPLMIHIPGMKDGGIQSQYGGEIDVLPTILHLLGISTK
NYIQFGTDLLSKQHDQVVAFRNNDYVTPTYSSIGGKLYDSSGNEITDPNTTFKKKVEKDRKAAKEQLAMSDSLNEKNLLR
FYKNPDFKKVNSANYNYSDGLTKAIKLEDKLGLKSTSMFSKNQDKSLEDLYKTNAPEANHKSTSENRIKITNPDANGS
>Mature_718_residues
MKSLKSKIDTRFGFFILITILFWAKTLFAYLADISLGVGSIFQWIILLINPVATTVLIFGLALYIRPKKIFYWVAMLLDV
ANTVMLYLNVIYFREFSDFMTVNTMLGYSKVNQGLSASSMSLTNVHDIFYWLDIIVIFLLLVLKKIKMDPHPLPKKFGFQ
ITSLGFLFFAFNLMLAEMDRPQLITRTFDRSYIVKYMGLDAFTAYDGVQLERNHKMRSEAKKSELTSIEKYVKHHYAKPS
NVTFAKAKGKNVIIIHLESFQQFLIDDKVEGQTVTPFLNSIYHSKSTYSFSNFFHQVGQGKTSDAENMLETGTFGTAQGS
LFAQLGSDQTFQAAPAILKQHGNYTSAVFHGNTASFWNRNSTYKNMGYENFFSASDFDVSGDKSTTYGLKDKLLFKDSIK
YLQHLQQPFYAKYITVSNHIPYTLDDEDSTFKTPSTGDKTVDNYFKTANYLDQSVEEFFNFLKKSGLYDDSMIVLYGDHY
GISNSSNTALAKTFEQDPDHFKEFGSNPTENWNNWDNSQLQRVPLMIHIPGMKDGGIQSQYGGEIDVLPTILHLLGISTK
NYIQFGTDLLSKQHDQVVAFRNNDYVTPTYSSIGGKLYDSSGNEITDPNTTFKKKVEKDRKAAKEQLAMSDSLNEKNLLR
FYKNPDFKKVNSANYNYSDGLTKAIKLEDKLGLKSTSMFSKNQDKSLEDLYKTNAPEANHKSTSENRIKITNPDANGS

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 81690; Mature: 81690

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHEEEHHHCCCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure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CHHHEEEHHHCCCCHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377; 10658653 [H]