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The map label for this gene is yieO [C]

Identifier: 116492142

GI number: 116492142

Start: 386865

End: 388286

Strand: Direct

Name: yieO [C]

Synonym: PEPE_0339

Alternate gene names: 116492142

Gene position: 386865-388286 (Clockwise)

Preceding gene: 116492140

Following gene: 116492143

Centisome position: 21.11

GC content: 36.57

Gene sequence:

>1422_bases
ATGAATAAGATTCGCCACCAGTTTGATCAATTGGTGCAAGGTGAATATCGTGAGGCCTTCATTCTGATTCTAGGAATGAT
TGTGATGCTGATTGGAGAGTTTTCAACCGCATTGGCAGTCACTAAAATTGTGGAAGCATTTGGAAATAATGAAGTTGTCG
TACAACTGACGAATATTTTACCTTTGGCTTGGTTAGCTTTAATGTATCCATTGGGCCCAGTTTGGTTGCAAAAAAAGTCA
GTCGTTCAGTTGTTAAAGTTATCCTTAGCTATTTTTATGATTGGTTCTTTATTAGTAGGGATAGCTTTTAATATGCCTAT
TTTATTACTGGGCCGGATTATTCAAACCACGGGGTGTGGAATTCTATTACCAATGCTTCCGAGTTTAATTGCGACAATTT
TACCAGAAAAAAATGTGGGTTTAACCAAAATGGGAGATGTTATGTTAGGAGTAGCGCTAGTTTTAGCCTTATTTCTAACC
GGAATATCCTTTTTATTGGGAAACTGGCAATTAATCAATATTTTCTTAATTGTTTTAAGTCTGATCATTTACCACAATGC
GTCAAGTATTAAAATCGATTTAGAAATCAGTACATATAATATTGAACGGGTAAACGTAGTTCTTTCGAGTGGCTTTATGG
TCTTCATTGGTTGGATAGTTACTTTGGGAGATCAAATCACGAGTAGCTGGTTTAGCTGGGGCTTATTGGTGATAGGTATT
GGTCTAATCGCAACTTATCTGTGGCGTGAATTATCTGTACCCAATCCGTTGATTGATTTTAAAGGATTATTCAATGTTCG
ATACTTGCGGGCTGTATTACTCCAAGGAATTGGAGATGCTTCCTTAGTAGTGTTAATGATTATCGGGATTTTATATTTGC
GTCAAGGATTACATTATTCGGTCATTATTATTGGATTAGCCTTGATGCCATCGATCGTCGTGATGATTTTAATGCATCAT
GCTACCAAACGATGGTTTAACAAATTCGAATCGGTCAATAACGTCAGAATGGCGATGAGCTTAATGATGGTGGGATGGGG
ATGTCTATCCTTGTTCTCAACCTACTTAAACCTAATTTTATTTATTGTTTTAACTATAATAATTGAAGCTGGGCATGGAT
TGTTAATGCAGGTGGGTCAAGAACTCAGCCAAAATCAAAAATCGGCACGTTTAAATAACATGGCCGATATTTTTATGGCT
CAGTTCAAATTGATGTCCTCAGGCATGATATTGGCAATTTTGTCAGTTGTTTTGCAGAATGTAACCAACAGTCACACTAG
TAACGGATTACCAGGTAAATTATCAACCCTCGTGGGATACCGAGCTACTTTTTCACTTTTCTTTGTGATTACAATTTTAG
GTTGGATTATCACGATGTTGGCAGGCAGAAACTTAAACTTAAGCAAACATATTGTAAAATAA

Upstream 100 bases:

>100_bases
TGTGCCACAATCGAATTTGAAAAAAGTTTTCGTTGCGCCTTTACTTTACCTTTTTTAATTAATAAAATTATAATTAAGCT
TATTTGAGGAGGGCGTATAC

Downstream 100 bases:

>100_bases
TTGGGGAATTCAAATGGATTTTAAAGTAGTTTTTAGAAAAACAAAAACGTTTTTAAGTGCTTTACTGAAGCGGTTCAACG
ATTCGGAAGTTGTAAATAAT

Product: major facilitator superfamily permease

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: Facilitator Superfamily Permease; Facilitator Superfamily Transporter Permease; Permease Of Facilitator Superfamily Protein; Multidrug Transporter; EmrB/QacA Subfamily Drug Resistance Transporter; Drug Resistance Transporter Emrb/Qaca Family Protein; Multidrug Resistance Protein; Efflux Transporter Protein; Drug Resistance Transporter; Drug Resistance Transporter EmrB/QacA Family Protein; Multidrug Resistance Protein B; Drug-Export Protein

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNKIRHQFDQLVQGEYREAFILILGMIVMLIGEFSTALAVTKIVEAFGNNEVVVQLTNILPLAWLALMYPLGPVWLQKKS
VVQLLKLSLAIFMIGSLLVGIAFNMPILLLGRIIQTTGCGILLPMLPSLIATILPEKNVGLTKMGDVMLGVALVLALFLT
GISFLLGNWQLINIFLIVLSLIIYHNASSIKIDLEISTYNIERVNVVLSSGFMVFIGWIVTLGDQITSSWFSWGLLVIGI
GLIATYLWRELSVPNPLIDFKGLFNVRYLRAVLLQGIGDASLVVLMIIGILYLRQGLHYSVIIIGLALMPSIVVMILMHH
ATKRWFNKFESVNNVRMAMSLMMVGWGCLSLFSTYLNLILFIVLTIIIEAGHGLLMQVGQELSQNQKSARLNNMADIFMA
QFKLMSSGMILAILSVVLQNVTNSHTSNGLPGKLSTLVGYRATFSLFFVITILGWIITMLAGRNLNLSKHIVK

Sequences:

>Translated_473_residues
MNKIRHQFDQLVQGEYREAFILILGMIVMLIGEFSTALAVTKIVEAFGNNEVVVQLTNILPLAWLALMYPLGPVWLQKKS
VVQLLKLSLAIFMIGSLLVGIAFNMPILLLGRIIQTTGCGILLPMLPSLIATILPEKNVGLTKMGDVMLGVALVLALFLT
GISFLLGNWQLINIFLIVLSLIIYHNASSIKIDLEISTYNIERVNVVLSSGFMVFIGWIVTLGDQITSSWFSWGLLVIGI
GLIATYLWRELSVPNPLIDFKGLFNVRYLRAVLLQGIGDASLVVLMIIGILYLRQGLHYSVIIIGLALMPSIVVMILMHH
ATKRWFNKFESVNNVRMAMSLMMVGWGCLSLFSTYLNLILFIVLTIIIEAGHGLLMQVGQELSQNQKSARLNNMADIFMA
QFKLMSSGMILAILSVVLQNVTNSHTSNGLPGKLSTLVGYRATFSLFFVITILGWIITMLAGRNLNLSKHIVK
>Mature_473_residues
MNKIRHQFDQLVQGEYREAFILILGMIVMLIGEFSTALAVTKIVEAFGNNEVVVQLTNILPLAWLALMYPLGPVWLQKKS
VVQLLKLSLAIFMIGSLLVGIAFNMPILLLGRIIQTTGCGILLPMLPSLIATILPEKNVGLTKMGDVMLGVALVLALFLT
GISFLLGNWQLINIFLIVLSLIIYHNASSIKIDLEISTYNIERVNVVLSSGFMVFIGWIVTLGDQITSSWFSWGLLVIGI
GLIATYLWRELSVPNPLIDFKGLFNVRYLRAVLLQGIGDASLVVLMIIGILYLRQGLHYSVIIIGLALMPSIVVMILMHH
ATKRWFNKFESVNNVRMAMSLMMVGWGCLSLFSTYLNLILFIVLTIIIEAGHGLLMQVGQELSQNQKSARLNNMADIFMA
QFKLMSSGMILAILSVVLQNVTNSHTSNGLPGKLSTLVGYRATFSLFFVITILGWIITMLAGRNLNLSKHIVK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52394; Mature: 52394

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIRHQFDQLVQGEYREAFILILGMIVMLIGEFSTALAVTKIVEAFGNNEVVVQLTNIL
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
PLAWLALMYPLGPVWLQKKSVVQLLKLSLAIFMIGSLLVGIAFNMPILLLGRIIQTTGCG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
ILLPMLPSLIATILPEKNVGLTKMGDVMLGVALVLALFLTGISFLLGNWQLINIFLIVLS
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LIIYHNASSIKIDLEISTYNIERVNVVLSSGFMVFIGWIVTLGDQITSSWFSWGLLVIGI
HHHHCCCCCEEEEEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLIATYLWRELSVPNPLIDFKGLFNVRYLRAVLLQGIGDASLVVLMIIGILYLRQGLHYS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHH
VIIIGLALMPSIVVMILMHHATKRWFNKFESVNNVRMAMSLMMVGWGCLSLFSTYLNLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVLTIIIEAGHGLLMQVGQELSQNQKSARLNNMADIFMAQFKLMSSGMILAILSVVLQN
HHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VTNSHTSNGLPGKLSTLVGYRATFSLFFVITILGWIITMLAGRNLNLSKHIVK
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MNKIRHQFDQLVQGEYREAFILILGMIVMLIGEFSTALAVTKIVEAFGNNEVVVQLTNIL
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHH
PLAWLALMYPLGPVWLQKKSVVQLLKLSLAIFMIGSLLVGIAFNMPILLLGRIIQTTGCG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCH
ILLPMLPSLIATILPEKNVGLTKMGDVMLGVALVLALFLTGISFLLGNWQLINIFLIVLS
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LIIYHNASSIKIDLEISTYNIERVNVVLSSGFMVFIGWIVTLGDQITSSWFSWGLLVIGI
HHHHCCCCCEEEEEEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLIATYLWRELSVPNPLIDFKGLFNVRYLRAVLLQGIGDASLVVLMIIGILYLRQGLHYS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHH
VIIIGLALMPSIVVMILMHHATKRWFNKFESVNNVRMAMSLMMVGWGCLSLFSTYLNLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVLTIIIEAGHGLLMQVGQELSQNQKSARLNNMADIFMAQFKLMSSGMILAILSVVLQN
HHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VTNSHTSNGLPGKLSTLVGYRATFSLFFVITILGWIITMLAGRNLNLSKHIVK
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA