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The map label for this gene is helD [H]

Identifier: 116492059

GI number: 116492059

Start: 302256

End: 304559

Strand: Reverse

Name: helD [H]

Synonym: PEPE_0255

Alternate gene names: 116492059

Gene position: 304559-302256 (Counterclockwise)

Preceding gene: 116492064

Following gene: 116492052

Centisome position: 16.62

GC content: 37.24

Gene sequence:

>2304_bases
TTGGACGAACAACAACAAGAACAGCAACGAGTTACGGAAGTCATTGAAAAAATCGACGAACAAAAACAACATACAGAAGA
TTTATATCATAAAGCCCATCAAGAAACTAGCCAGGTTGAAAGAAATTACTCACAAAATGCAAAGGTTAACTTGATTGAGG
CCGATGACCGCATCGAAACCCATGCTGAAATCCAACAGCAAAAAGGGCTGGTAGCTCGAGCTGTCGAGAATGAAGCAATT
TTAAAACGCCAAATTGATGAATTAAGCGATCTTCAAAAATCACCCTACTTTGGACGAATTGATATTAAAGATGCTGATGA
ACCTGATATTGAATCGCTTTACATTGGAATTTCGTCTTTTGCTGATCGGGATGGTAATTTCCTAATTTACGATTGGCGTG
CTCCTATTTCAAGCATTTACTACAATGGTACTCTGGGAAAAGTTAAATATGATACCCCAGCGGGCATGATGGAAACTGAA
CTCATTAAAAAACGTCAATTCACTATCAATCATGGTGAAATTCAACATATGTTCGACACTAACGAAACGGTTGGCGACGA
GCTTCTTCAACGAGCTTTAGGCGAACAAAATGACGAATACATGCGTAATATCGTCGCTACTATCCAAAAGGAACAAAACG
ACATAATCCGCGATGTTTATAGTGATCTTCTAGTCGTTCAGGGCGTGGCTGGTAGTGGTAAAACCTCTGCTATCCTACAA
CGTATCGCCTTTCTTTTATATCATAGCCGAACTTCATTAAATGCTGATGAAATTGTACTTTTTTCTCCTAATAAGTTGTA
TAGCCGTTATATTTCGGACGTTTTACCTAGTTTAGGGGAACGAAACATGCGTCAACTAACCTTAGCCGAATTTTTCAGCC
GCCGTTTGGAGGGCATGCAGGTCCAAACGTTATTTGACCGTTTTGAAAATCAACACCAACTCACTGAATACGAGCAAAAC
CTCATTGACTTTAAAGAAAGTCAGGATTTTATTGAATTAATTCAAGCTTATGAAAAACAACTTTCTACTAAAGAAATTAA
ATTTACCAATATTAATTACCGCGGCGAAATTTTCTTTTCTAAAGAACAAATTCAAGCTATCTTTGAAACCTTTCCTCTTA
GTATGAGCAATAAAGAACGTCTTTTAAAAACTAAAAATGCGCTAATCAAACTTCTTCAAAAACGAGTTAATCAGGAAATT
AAACAGGATTGGGTTCAAAATCAAATCGACCAAATTAGCGACGAAAAATATCATGGATTAGTGGGGACGCGTCACTTTAA
ATCATATGATGAGGAAAATCATTTTATCGGTCGCCAAATAGTTGATAAAGAATTCCAAATTATCGATGACGCTATCTTTA
ATAATTATTTCATCGATTCCTATTCTCAATACGCGGACTTTTTGAGTCAAATCGACTTAGGTGACTTCGATTGGCAAAAA
GTTGCTAAAGCTTTCACTGATGCAATTGAACTTCATCAGATTCATTTGGAAGATGCGGCACCCATGATGCTTCTCCGTGA
TTTGATTACTGGAAGTGGTACTAATCGTAAATTCCAATATGTATTCGTTGATGAAATGCAGGACTACTCAGTTGCACAAT
TAATGTACCTAAAACATGCTTTTCCTCGCGCTAAATTCACCTTACTAGGTGATAGTGAGCAGACCCTGTTCAAAGATGTT
ACCGAACCACAAATTCTATTAGCAAAACTAAAGCAGGCTTTTCATGTTAAGCGAGCTAATTTAATTACCTTAAATCGTAG
TTATCGCTCGACCGCCCAAATCACTAATTTTGCCGCGGCACTTCTACCTGATGGTCATAAAATTCAAGCTTTTAGTCGTG
AAGGAGATTTACCTAAAGTAATCATTGCTGATAATGAACAACAAGCCGTAGTCGATATGACCAATCTTTGCCGGGATGAA
TTACAGCAGTATGGTACCATCGCTATTTTAACTAAGAACATGGCTGAAAGTGAGCACGTAGCAACCTTGCTTCACGAATT
AAAACCGAGCTTATTAAACGATGGCGACCGTTCCTTACCCAAAGGTATTGTCGTTTTACCCATTTATTTAGCTAAAGGAT
TAGAGTTTGATTCCGTAATTGCCTATAATGTTTCCGAAGCTAATTTTCCTGGTCGTTTGTGGCGAGGAACTTTATATACG
ATAGCTTCCAGAGCCATGCATCAACTACACTTAATTAGTATTGGTAAAGTATCCAATTTAATTACCCAAATTAAGCCTGA
TCAATTTAGTTTTCAAAAATCATTTAACATCACTCCTCATAAATCACAAAAACTCGACGAATAA

Upstream 100 bases:

>100_bases
AAATAAGTTTAACTTTATCTCACAAGCTGGTCTTTCGGTTGACTTTCATTCTTCCTCCACCTAGAATTATTCAAGCATTA
AAATCAAGGAGGTGGCTGAT

Downstream 100 bases:

>100_bases
CCGTCGAGTTTTTTGTTTACATTACTTCAATTAATCCTACTCCAGCAATCATAATGATTAAGCCCGCAATCTTAGCAACT
GAGATGCTCGATTTCATCGA

Product: superfamily I DNA/RNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 767; Mature: 767

Protein sequence:

>767_residues
MDEQQQEQQRVTEVIEKIDEQKQHTEDLYHKAHQETSQVERNYSQNAKVNLIEADDRIETHAEIQQQKGLVARAVENEAI
LKRQIDELSDLQKSPYFGRIDIKDADEPDIESLYIGISSFADRDGNFLIYDWRAPISSIYYNGTLGKVKYDTPAGMMETE
LIKKRQFTINHGEIQHMFDTNETVGDELLQRALGEQNDEYMRNIVATIQKEQNDIIRDVYSDLLVVQGVAGSGKTSAILQ
RIAFLLYHSRTSLNADEIVLFSPNKLYSRYISDVLPSLGERNMRQLTLAEFFSRRLEGMQVQTLFDRFENQHQLTEYEQN
LIDFKESQDFIELIQAYEKQLSTKEIKFTNINYRGEIFFSKEQIQAIFETFPLSMSNKERLLKTKNALIKLLQKRVNQEI
KQDWVQNQIDQISDEKYHGLVGTRHFKSYDEENHFIGRQIVDKEFQIIDDAIFNNYFIDSYSQYADFLSQIDLGDFDWQK
VAKAFTDAIELHQIHLEDAAPMMLLRDLITGSGTNRKFQYVFVDEMQDYSVAQLMYLKHAFPRAKFTLLGDSEQTLFKDV
TEPQILLAKLKQAFHVKRANLITLNRSYRSTAQITNFAAALLPDGHKIQAFSREGDLPKVIIADNEQQAVVDMTNLCRDE
LQQYGTIAILTKNMAESEHVATLLHELKPSLLNDGDRSLPKGIVVLPIYLAKGLEFDSVIAYNVSEANFPGRLWRGTLYT
IASRAMHQLHLISIGKVSNLITQIKPDQFSFQKSFNITPHKSQKLDE

Sequences:

>Translated_767_residues
MDEQQQEQQRVTEVIEKIDEQKQHTEDLYHKAHQETSQVERNYSQNAKVNLIEADDRIETHAEIQQQKGLVARAVENEAI
LKRQIDELSDLQKSPYFGRIDIKDADEPDIESLYIGISSFADRDGNFLIYDWRAPISSIYYNGTLGKVKYDTPAGMMETE
LIKKRQFTINHGEIQHMFDTNETVGDELLQRALGEQNDEYMRNIVATIQKEQNDIIRDVYSDLLVVQGVAGSGKTSAILQ
RIAFLLYHSRTSLNADEIVLFSPNKLYSRYISDVLPSLGERNMRQLTLAEFFSRRLEGMQVQTLFDRFENQHQLTEYEQN
LIDFKESQDFIELIQAYEKQLSTKEIKFTNINYRGEIFFSKEQIQAIFETFPLSMSNKERLLKTKNALIKLLQKRVNQEI
KQDWVQNQIDQISDEKYHGLVGTRHFKSYDEENHFIGRQIVDKEFQIIDDAIFNNYFIDSYSQYADFLSQIDLGDFDWQK
VAKAFTDAIELHQIHLEDAAPMMLLRDLITGSGTNRKFQYVFVDEMQDYSVAQLMYLKHAFPRAKFTLLGDSEQTLFKDV
TEPQILLAKLKQAFHVKRANLITLNRSYRSTAQITNFAAALLPDGHKIQAFSREGDLPKVIIADNEQQAVVDMTNLCRDE
LQQYGTIAILTKNMAESEHVATLLHELKPSLLNDGDRSLPKGIVVLPIYLAKGLEFDSVIAYNVSEANFPGRLWRGTLYT
IASRAMHQLHLISIGKVSNLITQIKPDQFSFQKSFNITPHKSQKLDE
>Mature_767_residues
MDEQQQEQQRVTEVIEKIDEQKQHTEDLYHKAHQETSQVERNYSQNAKVNLIEADDRIETHAEIQQQKGLVARAVENEAI
LKRQIDELSDLQKSPYFGRIDIKDADEPDIESLYIGISSFADRDGNFLIYDWRAPISSIYYNGTLGKVKYDTPAGMMETE
LIKKRQFTINHGEIQHMFDTNETVGDELLQRALGEQNDEYMRNIVATIQKEQNDIIRDVYSDLLVVQGVAGSGKTSAILQ
RIAFLLYHSRTSLNADEIVLFSPNKLYSRYISDVLPSLGERNMRQLTLAEFFSRRLEGMQVQTLFDRFENQHQLTEYEQN
LIDFKESQDFIELIQAYEKQLSTKEIKFTNINYRGEIFFSKEQIQAIFETFPLSMSNKERLLKTKNALIKLLQKRVNQEI
KQDWVQNQIDQISDEKYHGLVGTRHFKSYDEENHFIGRQIVDKEFQIIDDAIFNNYFIDSYSQYADFLSQIDLGDFDWQK
VAKAFTDAIELHQIHLEDAAPMMLLRDLITGSGTNRKFQYVFVDEMQDYSVAQLMYLKHAFPRAKFTLLGDSEQTLFKDV
TEPQILLAKLKQAFHVKRANLITLNRSYRSTAQITNFAAALLPDGHKIQAFSREGDLPKVIIADNEQQAVVDMTNLCRDE
LQQYGTIAILTKNMAESEHVATLLHELKPSLLNDGDRSLPKGIVVLPIYLAKGLEFDSVIAYNVSEANFPGRLWRGTLYT
IASRAMHQLHLISIGKVSNLITQIKPDQFSFQKSFNITPHKSQKLDE

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 88688; Mature: 88688

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQQQEQQRVTEVIEKIDEQKQHTEDLYHKAHQETSQVERNYSQNAKVNLIEADDRIET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
HAEIQQQKGLVARAVENEAILKRQIDELSDLQKSPYFGRIDIKDADEPDIESLYIGISSF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEHHHH
ADRDGNFLIYDWRAPISSIYYNGTLGKVKYDTPAGMMETELIKKRQFTINHGEIQHMFDT
CCCCCCEEEEECCCCHHHEEECCCCCEEEECCCCCHHHHHHHHHHCEEECCCCCHHHHCC
NETVGDELLQRALGEQNDEYMRNIVATIQKEQNDIIRDVYSDLLVVQGVAGSGKTSAILQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RIAFLLYHSRTSLNADEIVLFSPNKLYSRYISDVLPSLGERNMRQLTLAEFFSRRLEGMQ
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCH
VQTLFDRFENQHQLTEYEQNLIDFKESQDFIELIQAYEKQLSTKEIKFTNINYRGEIFFS
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEC
KEQIQAIFETFPLSMSNKERLLKTKNALIKLLQKRVNQEIKQDWVQNQIDQISDEKYHGL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
VGTRHFKSYDEENHFIGRQIVDKEFQIIDDAIFNNYFIDSYSQYADFLSQIDLGDFDWQK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCHHH
VAKAFTDAIELHQIHLEDAAPMMLLRDLITGSGTNRKFQYVFVDEMQDYSVAQLMYLKHA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
FPRAKFTLLGDSEQTLFKDVTEPQILLAKLKQAFHVKRANLITLNRSYRSTAQITNFAAA
CCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
LLPDGHKIQAFSREGDLPKVIIADNEQQAVVDMTNLCRDELQQYGTIAILTKNMAESEHV
HCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHH
ATLLHELKPSLLNDGDRSLPKGIVVLPIYLAKGLEFDSVIAYNVSEANFPGRLWRGTLYT
HHHHHHHCHHHHCCCCCCCCCCEEEEEHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHH
IASRAMHQLHLISIGKVSNLITQIKPDQFSFQKSFNITPHKSQKLDE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEQQQEQQRVTEVIEKIDEQKQHTEDLYHKAHQETSQVERNYSQNAKVNLIEADDRIET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHH
HAEIQQQKGLVARAVENEAILKRQIDELSDLQKSPYFGRIDIKDADEPDIESLYIGISSF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEHHHH
ADRDGNFLIYDWRAPISSIYYNGTLGKVKYDTPAGMMETELIKKRQFTINHGEIQHMFDT
CCCCCCEEEEECCCCHHHEEECCCCCEEEECCCCCHHHHHHHHHHCEEECCCCCHHHHCC
NETVGDELLQRALGEQNDEYMRNIVATIQKEQNDIIRDVYSDLLVVQGVAGSGKTSAILQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RIAFLLYHSRTSLNADEIVLFSPNKLYSRYISDVLPSLGERNMRQLTLAEFFSRRLEGMQ
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCH
VQTLFDRFENQHQLTEYEQNLIDFKESQDFIELIQAYEKQLSTKEIKFTNINYRGEIFFS
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEC
KEQIQAIFETFPLSMSNKERLLKTKNALIKLLQKRVNQEIKQDWVQNQIDQISDEKYHGL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
VGTRHFKSYDEENHFIGRQIVDKEFQIIDDAIFNNYFIDSYSQYADFLSQIDLGDFDWQK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCHHH
VAKAFTDAIELHQIHLEDAAPMMLLRDLITGSGTNRKFQYVFVDEMQDYSVAQLMYLKHA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
FPRAKFTLLGDSEQTLFKDVTEPQILLAKLKQAFHVKRANLITLNRSYRSTAQITNFAAA
CCCCEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHH
LLPDGHKIQAFSREGDLPKVIIADNEQQAVVDMTNLCRDELQQYGTIAILTKNMAESEHV
HCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHH
ATLLHELKPSLLNDGDRSLPKGIVVLPIYLAKGLEFDSVIAYNVSEANFPGRLWRGTLYT
HHHHHHHCHHHHCCCCCCCCCCEEEEEHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHH
IASRAMHQLHLISIGKVSNLITQIKPDQFSFQKSFNITPHKSQKLDE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]