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The map label for this gene is xylB [H]

Identifier: 116491993

GI number: 116491993

Start: 213441

End: 214562

Strand: Reverse

Name: xylB [H]

Synonym: PEPE_0182

Alternate gene names: 116491993

Gene position: 214562-213441 (Counterclockwise)

Preceding gene: 116491995

Following gene: 116491975

Centisome position: 11.71

GC content: 40.29

Gene sequence:

>1122_bases
ATGAAAATTAAAGCAGCAGTTGTCGATCAACAAAATAGTGATTTTAAGATTAAAGATGATATTGAATTAGCTGAAATGGG
GCCAGACGATATTCAAGTTCATATGGTTGCCAGTGGAATTTGTCATTCTGACGAAGCTCTACGGGTGGGCGATGCTATTA
TTGATTATCCGATTGTTCTTGGCCATGAAGGTTCCGGAATCGTTGAAAAAGTTGGACCAGAAGTTACACAATTTAAACCT
GGCGACCATGTCATTCTAAGTTTCTATGCTTGTGGAAATTGCGATAATTGTCTACGTGGAATCCCAACTCAATGCCGTAA
CTACGCCGCTAACAACCTTTCTGGTGTACGTCCAGATGGCTCAAGCCACTTCACTGAAAATGGCAAGCACGTTGCAGATA
TGTTTGACCAAAGTTCATTCACTTCTACGACCGTTGTTCGTGAACGAAATGCCGTTAAAATTGATGACGATATCGATCTT
CGTAAAGTTGGACCACTTGGATGTGGCTATGTAACTGGTTCAGGTACCGTTCTCAACACTCTTCAACCACGTCCCGGTGA
CACCATCGCCGTATTTGGTACAGGAGCCGTTGGTTTAGCAGCTATGATGGCTGGTAAGATTTCTGGTTGTACAAAAGTGA
TTGGAATTGATATTGTTGATTCTCGTTTAGCCTTAGCCAAAGAATTAGGTGCTACTGACATTATCAACAGTAAAAATGTT
GATGTAGTCGAAGAAGTGAAAAAATTAACTGGCGGCCTCGGAGTTAATTGGGCTGTTGACACAACTGGTATCACTAAAGT
CATGGAAGATTCCATCAAAGTTCTAACCCAAGGTGGTACCACTGCAACTATCGCTGTAACACCAAATCACATTGACCTTG
ATACTTGGAATGATCTTTGTGTAGATGACAAGAAGATTGTCGGTGTCAACATGGGCGATTCGATTCCACAAATTGACATC
CCTCGTTTAATCGAATTCTACAAAGCTGGCATGTTTGATTTTGATAAGACTGAAAAATTCTTTAATTTTGACGAAATTAA
TGAAGCAAATGCTGCTTCTCGTTCAGGTGAAGTTATTAAACCGGTTTTAATTATTGATCCTGATTATGTGCCTGGTAAAT
AA

Upstream 100 bases:

>100_bases
ATAAGTTATTTATACAAAGTTAGTTTTGCAAACGCTTTCTTTTTGTGAAATAATTAGTTTATGAATCATACATACCAATC
CACAAAGGAGATCTTAGTTC

Downstream 100 bases:

>100_bases
AAGAATTTTAACTAATCACCAAAAGTGAAGATACAAAAAATCCATTCAGTGAGGATCCTCACTGAATGGATTTATTTTAA
TTTCCTAAAAATGTTTAAAA

Product: Zn-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKIKAAVVDQQNSDFKIKDDIELAEMGPDDIQVHMVASGICHSDEALRVGDAIIDYPIVLGHEGSGIVEKVGPEVTQFKP
GDHVILSFYACGNCDNCLRGIPTQCRNYAANNLSGVRPDGSSHFTENGKHVADMFDQSSFTSTTVVRERNAVKIDDDIDL
RKVGPLGCGYVTGSGTVLNTLQPRPGDTIAVFGTGAVGLAAMMAGKISGCTKVIGIDIVDSRLALAKELGATDIINSKNV
DVVEEVKKLTGGLGVNWAVDTTGITKVMEDSIKVLTQGGTTATIAVTPNHIDLDTWNDLCVDDKKIVGVNMGDSIPQIDI
PRLIEFYKAGMFDFDKTEKFFNFDEINEANAASRSGEVIKPVLIIDPDYVPGK

Sequences:

>Translated_373_residues
MKIKAAVVDQQNSDFKIKDDIELAEMGPDDIQVHMVASGICHSDEALRVGDAIIDYPIVLGHEGSGIVEKVGPEVTQFKP
GDHVILSFYACGNCDNCLRGIPTQCRNYAANNLSGVRPDGSSHFTENGKHVADMFDQSSFTSTTVVRERNAVKIDDDIDL
RKVGPLGCGYVTGSGTVLNTLQPRPGDTIAVFGTGAVGLAAMMAGKISGCTKVIGIDIVDSRLALAKELGATDIINSKNV
DVVEEVKKLTGGLGVNWAVDTTGITKVMEDSIKVLTQGGTTATIAVTPNHIDLDTWNDLCVDDKKIVGVNMGDSIPQIDI
PRLIEFYKAGMFDFDKTEKFFNFDEINEANAASRSGEVIKPVLIIDPDYVPGK
>Mature_373_residues
MKIKAAVVDQQNSDFKIKDDIELAEMGPDDIQVHMVASGICHSDEALRVGDAIIDYPIVLGHEGSGIVEKVGPEVTQFKP
GDHVILSFYACGNCDNCLRGIPTQCRNYAANNLSGVRPDGSSHFTENGKHVADMFDQSSFTSTTVVRERNAVKIDDDIDL
RKVGPLGCGYVTGSGTVLNTLQPRPGDTIAVFGTGAVGLAAMMAGKISGCTKVIGIDIVDSRLALAKELGATDIINSKNV
DVVEEVKKLTGGLGVNWAVDTTGITKVMEDSIKVLTQGGTTATIAVTPNHIDLDTWNDLCVDDKKIVGVNMGDSIPQIDI
PRLIEFYKAGMFDFDKTEKFFNFDEINEANAASRSGEVIKPVLIIDPDYVPGK

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=35.5978260869565, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=35.054347826087, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI4501929, Length=370, Percent_Identity=34.3243243243243, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI71565152, Length=380, Percent_Identity=34.4736842105263, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI71565154, Length=371, Percent_Identity=33.9622641509434, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI156523966, Length=371, Percent_Identity=30.9973045822102, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI4501939, Length=363, Percent_Identity=31.129476584022, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI262073058, Length=373, Percent_Identity=32.9758713136729, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI71743840, Length=373, Percent_Identity=32.9758713136729, Blast_Score=181, Evalue=8e-46,
Organism=Escherichia coli, GI1786552, Length=372, Percent_Identity=32.258064516129, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081918, Length=331, Percent_Identity=29.607250755287, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788407, Length=295, Percent_Identity=25.0847457627119, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788073, Length=266, Percent_Identity=27.4436090225564, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082125, Length=379, Percent_Identity=24.2744063324538, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790045, Length=358, Percent_Identity=24.8603351955307, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788075, Length=313, Percent_Identity=24.2811501597444, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786518, Length=378, Percent_Identity=26.7195767195767, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787863, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082401, Length=350, Percent_Identity=21.4285714285714, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25146526, Length=378, Percent_Identity=34.1269841269841, Blast_Score=190, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI71997431, Length=380, Percent_Identity=33.9473684210526, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17565904, Length=342, Percent_Identity=35.0877192982456, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17562876, Length=360, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562878, Length=261, Percent_Identity=28.3524904214559, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=289, Percent_Identity=27.3356401384083, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=284, Percent_Identity=25.7042253521127, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320033, Length=350, Percent_Identity=34, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319258, Length=309, Percent_Identity=27.5080906148867, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=365, Percent_Identity=25.2054794520548, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=362, Percent_Identity=24.8618784530387, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323099, Length=274, Percent_Identity=25.9124087591241, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=257, Percent_Identity=29.1828793774319, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=367, Percent_Identity=25.0681198910082, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=335, Percent_Identity=25.9701492537313, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=335, Percent_Identity=24.7761194029851, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319257, Length=294, Percent_Identity=23.1292517006803, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737895, Length=368, Percent_Identity=33.695652173913, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17137530, Length=242, Percent_Identity=29.7520661157025, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737897, Length=237, Percent_Identity=28.2700421940928, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 39979; Mature: 39979

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKAAVVDQQNSDFKIKDDIELAEMGPDDIQVHMVASGICHSDEALRVGDAIIDYPIVL
CCEEEEEECCCCCCEEEECCCCHHHCCCCCEEEEEEECCCCCCCCHHHHCCHHCCCCEEE
GHEGSGIVEKVGPEVTQFKPGDHVILSFYACGNCDNCLRGIPTQCRNYAANNLSGVRPDG
ECCCCCHHHHCCCCCEEECCCCEEEEEEEECCCHHHHHHCCCHHHHHHHHCCCCCCCCCC
SSHFTENGKHVADMFDQSSFTSTTVVRERNAVKIDDDIDLRKVGPLGCGYVTGSGTVLNT
CCCCCCCCCCHHHHHCCCCCCCEEEEECCCCEEECCCCCCEECCCCCCEEEECCCEEEEC
LQPRPGDTIAVFGTGAVGLAAMMAGKISGCTKVIGIDIVDSRLALAKELGATDIINSKNV
CCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHHHCCCHHCCCCCCC
DVVEEVKKLTGGLGVNWAVDTTGITKVMEDSIKVLTQGGTTATIAVTPNHIDLDTWNDLC
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHEEECCCCEEEEEECCCEEECCCCCCCC
VDDKKIVGVNMGDSIPQIDIPRLIEFYKAGMFDFDKTEKFFNFDEINEANAASRSGEVIK
CCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCHHHCCCCCCCCCCCCEEE
PVLIIDPDYVPGK
EEEEECCCCCCCC
>Mature Secondary Structure
MKIKAAVVDQQNSDFKIKDDIELAEMGPDDIQVHMVASGICHSDEALRVGDAIIDYPIVL
CCEEEEEECCCCCCEEEECCCCHHHCCCCCEEEEEEECCCCCCCCHHHHCCHHCCCCEEE
GHEGSGIVEKVGPEVTQFKPGDHVILSFYACGNCDNCLRGIPTQCRNYAANNLSGVRPDG
ECCCCCHHHHCCCCCEEECCCCEEEEEEEECCCHHHHHHCCCHHHHHHHHCCCCCCCCCC
SSHFTENGKHVADMFDQSSFTSTTVVRERNAVKIDDDIDLRKVGPLGCGYVTGSGTVLNT
CCCCCCCCCCHHHHHCCCCCCCEEEEECCCCEEECCCCCCEECCCCCCEEEECCCEEEEC
LQPRPGDTIAVFGTGAVGLAAMMAGKISGCTKVIGIDIVDSRLALAKELGATDIINSKNV
CCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHHHCCCHHCCCCCCC
DVVEEVKKLTGGLGVNWAVDTTGITKVMEDSIKVLTQGGTTATIAVTPNHIDLDTWNDLC
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHEEECCCCEEEEEECCCEEECCCCCCCC
VDDKKIVGVNMGDSIPQIDIPRLIEFYKAGMFDFDKTEKFFNFDEINEANAASRSGEVIK
CCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCHHHCCCCCCCCCCCCEEE
PVLIIDPDYVPGK
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]