Definition Pediococcus pentosaceus ATCC 25745, complete genome.
Accession NC_008525
Length 1,832,387

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The map label for this gene is yghA [H]

Identifier: 116491960

GI number: 116491960

Start: 174070

End: 174963

Strand: Direct

Name: yghA [H]

Synonym: PEPE_0146

Alternate gene names: 116491960

Gene position: 174070-174963 (Clockwise)

Preceding gene: 116491958

Following gene: 116491961

Centisome position: 9.5

GC content: 46.98

Gene sequence:

>894_bases
ATGAGTAAACCAGATTTAAAGGATCCACGAAAGTTGTATCATACAGAAGAATTTCCAAAACAACAACAGGATACACCAGC
ACTACAGAGTGAGATGCGACCTAAACCAGACTGTGGTGAAGAAACTTACGAAGGTCACGGACTATTGCTAGATCGTAAAG
CGTTAGTAACCGGTGGTGATTCAGGAATCGGTCGAGCGACTGCAATTGCCTTCGCTCGCGAAGGAGCAGACGTTGCCATC
CAGTATTTCCCTGGAGAAGATTCAGATGCGAAGGAAGTCGCGGAATACATCGAAAAAGCGGGCCGGAAGGCAGTTTTATT
GCCATACGATTTCCGAGACGAAAAGGCCCCTCAAGAAGTGGTTGATCGCGTGGTTGAAGAGTTGGGCGGTTTAGACACGA
TGGTGTTGAATGCCGGCCAACAAATTGCCCATAAAAAGATTGATGACCTCCCCGTGCAACAAATTAGAGACAGTTTCGAA
GTGAACGTGGTGGCAATGTTGGCCCTAGTGAAGGCGGCTAAACCACACATTCCAGCGGGAGGCGCCATCGTTACTACGAC
TTCGGTCCAAGCCTTTAATCCAAGTAGCCAATTGTTGGACTATGCGGCAACGAAGGCAGCAATCGCTAATTTTACCATCA
ACTTAGCTCAGCAGTTAATCGAAGACGGAATTCGGGTAAATGGTGTCGCACCAGGCCCAATTTGGACACCAATTCAGTTA
GATCACGGACAGCCGGAGGAAGCTATCCCAGAATTTGGACAAAAATCATTAATGGGTCGGGCAGGTCAACCGGCTGAACT
AGCTCCAACGTATGTCTTATTGGCTTCTAACTTAGCAAGTTATACTACTGCCCAAATATATGGTGTTACTGGTGGAGAAC
ACATCAACTTATAA

Upstream 100 bases:

>100_bases
ATCCTCCTTTCGTAAAACGGTTACATCGTTGAAGCATATTACTTTATAAAGCAATTCTATTCGATTAGAATTTGAATTAC
AAAAGAAAGGGAGTGAATTA

Downstream 100 bases:

>100_bases
GGGGAAAGTCATATGCCATGGACGAAAAAAGATTATCCAGAGTCGATGAAAAACTTGTCAGAAACCGTGCGGAATAAAGC
GATTGAAATTGCTAACGCAC

Product: Short-chain alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSKPDLKDPRKLYHTEEFPKQQQDTPALQSEMRPKPDCGEETYEGHGLLLDRKALVTGGDSGIGRATAIAFAREGADVAI
QYFPGEDSDAKEVAEYIEKAGRKAVLLPYDFRDEKAPQEVVDRVVEELGGLDTMVLNAGQQIAHKKIDDLPVQQIRDSFE
VNVVAMLALVKAAKPHIPAGGAIVTTTSVQAFNPSSQLLDYAATKAAIANFTINLAQQLIEDGIRVNGVAPGPIWTPIQL
DHGQPEEAIPEFGQKSLMGRAGQPAELAPTYVLLASNLASYTTAQIYGVTGGEHINL

Sequences:

>Translated_297_residues
MSKPDLKDPRKLYHTEEFPKQQQDTPALQSEMRPKPDCGEETYEGHGLLLDRKALVTGGDSGIGRATAIAFAREGADVAI
QYFPGEDSDAKEVAEYIEKAGRKAVLLPYDFRDEKAPQEVVDRVVEELGGLDTMVLNAGQQIAHKKIDDLPVQQIRDSFE
VNVVAMLALVKAAKPHIPAGGAIVTTTSVQAFNPSSQLLDYAATKAAIANFTINLAQQLIEDGIRVNGVAPGPIWTPIQL
DHGQPEEAIPEFGQKSLMGRAGQPAELAPTYVLLASNLASYTTAQIYGVTGGEHINL
>Mature_296_residues
SKPDLKDPRKLYHTEEFPKQQQDTPALQSEMRPKPDCGEETYEGHGLLLDRKALVTGGDSGIGRATAIAFAREGADVAIQ
YFPGEDSDAKEVAEYIEKAGRKAVLLPYDFRDEKAPQEVVDRVVEELGGLDTMVLNAGQQIAHKKIDDLPVQQIRDSFEV
NVVAMLALVKAAKPHIPAGGAIVTTTSVQAFNPSSQLLDYAATKAAIANFTINLAQQLIEDGIRVNGVAPGPIWTPIQLD
HGQPEEAIPEFGQKSLMGRAGQPAELAPTYVLLASNLASYTTAQIYGVTGGEHINL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=30.3030303030303, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=28.4552845528455, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=31.7460317460317, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=29.3103448275862, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=29.3269230769231, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=33.6734693877551, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=27.4436090225564, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=27.5590551181102, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4758504, Length=229, Percent_Identity=28.3842794759825, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789378, Length=291, Percent_Identity=58.4192439862543, Blast_Score=346, Evalue=1e-96,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.1463414634146, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=33.852140077821, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=32.8, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=31.2757201646091, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=28.1632653061224, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=26.4227642276423, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=29.8850574712644, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=31.1284046692607, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=29.9212598425197, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=32.5301204819277, Blast_Score=81, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=31.7460317460317, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=32.2709163346614, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=31.6602316602317, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=32.3076923076923, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=31.1787072243346, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=32.3886639676113, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=31.4176245210728, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=32.6923076923077, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=31.6793893129771, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=242, Percent_Identity=29.3388429752066, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=30.9160305343511, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=28.7313432835821, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.4776119402985, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=29.1187739463602, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.9850746268657, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=198, Percent_Identity=32.3232323232323, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=240, Percent_Identity=27.5, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=29.1970802919708, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=30, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=260, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=271, Percent_Identity=28.0442804428044, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=28.7179487179487, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=28.5140562248996, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=30.6772908366534, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32.4, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=32.2709163346614, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=32.1138211382114, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=31.8725099601594, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17737361, Length=230, Percent_Identity=33.9130434782609, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644337, Length=119, Percent_Identity=38.655462184874, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32041; Mature: 31909

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSKPDLKDPRKLYHTEEFPKQQQDTPALQSEMRPKPDCGEETYEGHGLLLDRKALVTGGD
CCCCCCCCHHHHHCCHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCEEEECCC
SGIGRATAIAFAREGADVAIQYFPGEDSDAKEVAEYIEKAGRKAVLLPYDFRDEKAPQEV
CCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
VDRVVEELGGLDTMVLNAGQQIAHKKIDDLPVQQIRDSFEVNVVAMLALVKAAKPHIPAG
HHHHHHHHCCCCEEHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAIVTTTSVQAFNPSSQLLDYAATKAAIANFTINLAQQLIEDGIRVNGVAPGPIWTPIQL
CEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEE
DHGQPEEAIPEFGQKSLMGRAGQPAELAPTYVLLASNLASYTTAQIYGVTGGEHINL
CCCCCHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHEEEEEECCCCCCCCC
>Mature Secondary Structure 
SKPDLKDPRKLYHTEEFPKQQQDTPALQSEMRPKPDCGEETYEGHGLLLDRKALVTGGD
CCCCCCCHHHHHCCHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEECCEEEECCC
SGIGRATAIAFAREGADVAIQYFPGEDSDAKEVAEYIEKAGRKAVLLPYDFRDEKAPQEV
CCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
VDRVVEELGGLDTMVLNAGQQIAHKKIDDLPVQQIRDSFEVNVVAMLALVKAAKPHIPAG
HHHHHHHHCCCCEEHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAIVTTTSVQAFNPSSQLLDYAATKAAIANFTINLAQQLIEDGIRVNGVAPGPIWTPIQL
CEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEE
DHGQPEEAIPEFGQKSLMGRAGQPAELAPTYVLLASNLASYTTAQIYGVTGGEHINL
CCCCCHHHHHHHHHHHHHCCCCCCCHHCHHHHHHHHHHHHHHEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]