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The map label for this gene is dapE [H]

Identifier: 116491925

GI number: 116491925

Start: 121990

End: 123141

Strand: Reverse

Name: dapE [H]

Synonym: PEPE_0111

Alternate gene names: 116491925

Gene position: 123141-121990 (Counterclockwise)

Preceding gene: 116491933

Following gene: 116491912

Centisome position: 6.72

GC content: 39.32

Gene sequence:

>1152_bases
ATGGATACTATGGTTTCAAATTCGCAAACATATCTAAAAATTTTAGCTGATTTAATTAAAATCAAATCTGTTAACGATCA
CGAATTAGAAGTTGCAGAATATTTGCAGGATTTATTCCAAGAAAATGGCATTGAGGCAAAAATTCTCCCACTTGAGGGTC
AGCGGGCTAATCTAGTTGCCGAAATTGGGGAAGGCGCTCCTGTCTTAGCTGTTTCCGGACACATGGATGTCGTTGATCCT
GGAAATTTGGCTGCATGGGATAATGATCCATTTACCATGACTGAAAAAGATGGCAAACTCTTTGGTCGCGGAATTACAGA
TATGAAGGCTGGTTTAGCAGCTTTAGTAATTGCCATGATTGAATTGAAAAAACAAGGCTTACCCAAAAAAGGTACAATTC
GTTTGCTAGCAACTGCCGGAGAAGAGGTTGGTGAAGAAGGTTCCGCCGCCTTTTATCGCGATCATTATATGGAAGACGCA
GCGGGCTTGCTAATTGCGGAGCCTTCTACCGTCTACGGTACTGCTTCTGAACAAAAAGGTTCTTTCGATATTAAATTTAC
TTCTAAAGGTACTTCCGTTCATAGCTCTACTCCTGAAAAAGGTTACAACGCTCTAGTACCGTTGATGCAACTATTGAATG
AAGCTAATACCTACTTCGAAACGATTCCAGCCGGAGAGATGGGACCAGTACGTTTCAACATTGACGTTTTGAATGGTGGT
AGTCAGATTAATTCCTTACCTGATTTAGCTACCGCTTTGGTCAACGTTCGTACGATTCCAGAATACGATAATAACCAAGT
GGCTAAGCAGATTGAAACATTCGTTAAATCTTACAATGCAAATGGAGCTCAAATTAATACAGACTTAATTATGAATGAAT
TTCCAATTGCTACGAGTCCTTCCAACCAGTTAGTTAAAATTATTCAGTCACTAGGTAAAGAATATGCAGGACGTGATATT
GTCGTGGCTGCAAGCCCCGGAATTACCGATGCTTCTAATCTAGCTAAGGATAAGCCGCATGATTTTCCTTTTGCTGTATA
TGGGCCAGGAGATGGTTCCCAACATCAAGTTAACGAAAGTTTACCTAAACAGATGTATTTAGACTTCATTGAAATCTATC
AAAAATTATTTATTGAATTCCTCGAAAAATAA

Upstream 100 bases:

>100_bases
AATTTCGGCTGAATCTTTAGAAATGTGTAACTTATGTTTTTAGTGGCAGTTTTAGTAAAAAAAGCGTAAGCTATTTTATT
GAAAAAGGATGAAGGAAGGA

Downstream 100 bases:

>100_bases
TATTACCTACTAAAAAGAATCGTTAGCGATGATGGCTGACGATTCTTTTAATATGTTCTCATTAGGTTATTCGCAATCTA
AATGGAACTTAATTTATGCC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDTMVSNSQTYLKILADLIKIKSVNDHELEVAEYLQDLFQENGIEAKILPLEGQRANLVAEIGEGAPVLAVSGHMDVVDP
GNLAAWDNDPFTMTEKDGKLFGRGITDMKAGLAALVIAMIELKKQGLPKKGTIRLLATAGEEVGEEGSAAFYRDHYMEDA
AGLLIAEPSTVYGTASEQKGSFDIKFTSKGTSVHSSTPEKGYNALVPLMQLLNEANTYFETIPAGEMGPVRFNIDVLNGG
SQINSLPDLATALVNVRTIPEYDNNQVAKQIETFVKSYNANGAQINTDLIMNEFPIATSPSNQLVKIIQSLGKEYAGRDI
VVAASPGITDASNLAKDKPHDFPFAVYGPGDGSQHQVNESLPKQMYLDFIEIYQKLFIEFLEK

Sequences:

>Translated_383_residues
MDTMVSNSQTYLKILADLIKIKSVNDHELEVAEYLQDLFQENGIEAKILPLEGQRANLVAEIGEGAPVLAVSGHMDVVDP
GNLAAWDNDPFTMTEKDGKLFGRGITDMKAGLAALVIAMIELKKQGLPKKGTIRLLATAGEEVGEEGSAAFYRDHYMEDA
AGLLIAEPSTVYGTASEQKGSFDIKFTSKGTSVHSSTPEKGYNALVPLMQLLNEANTYFETIPAGEMGPVRFNIDVLNGG
SQINSLPDLATALVNVRTIPEYDNNQVAKQIETFVKSYNANGAQINTDLIMNEFPIATSPSNQLVKIIQSLGKEYAGRDI
VVAASPGITDASNLAKDKPHDFPFAVYGPGDGSQHQVNESLPKQMYLDFIEIYQKLFIEFLEK
>Mature_383_residues
MDTMVSNSQTYLKILADLIKIKSVNDHELEVAEYLQDLFQENGIEAKILPLEGQRANLVAEIGEGAPVLAVSGHMDVVDP
GNLAAWDNDPFTMTEKDGKLFGRGITDMKAGLAALVIAMIELKKQGLPKKGTIRLLATAGEEVGEEGSAAFYRDHYMEDA
AGLLIAEPSTVYGTASEQKGSFDIKFTSKGTSVHSSTPEKGYNALVPLMQLLNEANTYFETIPAGEMGPVRFNIDVLNGG
SQINSLPDLATALVNVRTIPEYDNNQVAKQIETFVKSYNANGAQINTDLIMNEFPIATSPSNQLVKIIQSLGKEYAGRDI
VVAASPGITDASNLAKDKPHDFPFAVYGPGDGSQHQVNESLPKQMYLDFIEIYQKLFIEFLEK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=367, Percent_Identity=26.4305177111717, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789236, Length=206, Percent_Identity=27.6699029126214, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788816, Length=336, Percent_Identity=25.8928571428571, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982710, Length=329, Percent_Identity=26.4437689969605, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538640, Length=225, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649208, Length=394, Percent_Identity=24.8730964467005, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 41668; Mature: 41668

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTMVSNSQTYLKILADLIKIKSVNDHELEVAEYLQDLFQENGIEAKILPLEGQRANLVA
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHE
EIGEGAPVLAVSGHMDVVDPGNLAAWDNDPFTMTEKDGKLFGRGITDMKAGLAALVIAMI
ECCCCCCEEEECCCCCEECCCCEEEECCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHH
ELKKQGLPKKGTIRLLATAGEEVGEEGSAAFYRDHYMEDAAGLLIAEPSTVYGTASEQKG
HHHHHCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHCCEEEECCCEEEECCCCCCC
SFDIKFTSKGTSVHSSTPEKGYNALVPLMQLLNEANTYFETIPAGEMGPVRFNIDVLNGG
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
SQINSLPDLATALVNVRTIPEYDNNQVAKQIETFVKSYNANGAQINTDLIMNEFPIATSP
CHHCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHEEECCCCCCCC
SNQLVKIIQSLGKEYAGRDIVVAASPGITDASNLAKDKPHDFPFAVYGPGDGSQHQVNES
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCCCCEEEECCCCCCCHHHHHH
LPKQMYLDFIEIYQKLFIEFLEK
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTMVSNSQTYLKILADLIKIKSVNDHELEVAEYLQDLFQENGIEAKILPLEGQRANLVA
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHE
EIGEGAPVLAVSGHMDVVDPGNLAAWDNDPFTMTEKDGKLFGRGITDMKAGLAALVIAMI
ECCCCCCEEEECCCCCEECCCCEEEECCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHH
ELKKQGLPKKGTIRLLATAGEEVGEEGSAAFYRDHYMEDAAGLLIAEPSTVYGTASEQKG
HHHHHCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHCCEEEECCCEEEECCCCCCC
SFDIKFTSKGTSVHSSTPEKGYNALVPLMQLLNEANTYFETIPAGEMGPVRFNIDVLNGG
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
SQINSLPDLATALVNVRTIPEYDNNQVAKQIETFVKSYNANGAQINTDLIMNEFPIATSP
CHHCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHEEECCCCCCCC
SNQLVKIIQSLGKEYAGRDIVVAASPGITDASNLAKDKPHDFPFAVYGPGDGSQHQVNES
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCCCCEEEECCCCCCCHHHHHH
LPKQMYLDFIEIYQKLFIEFLEK
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA