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The map label for this gene is yhcG [H]

Identifier: 116491871

GI number: 116491871

Start: 48900

End: 49604

Strand: Reverse

Name: yhcG [H]

Synonym: PEPE_0053

Alternate gene names: 116491871

Gene position: 49604-48900 (Counterclockwise)

Preceding gene: 116491872

Following gene: 116491870

Centisome position: 2.71

GC content: 38.3

Gene sequence:

>705_bases
ATGGCTAATCTACTAACAATTAATCATTTAAGCTATTCTCGTAATCTCCAATTAATCCTAAAAGACCTCAATTTAGAGCT
TCCGTACGGGCAAATTGTAGGCTTGTTGGGTACCAATGGTGCTGGTAAAACGACGTTAATGCGTTTGATTGCTGGAAATT
ATATTGATCGTAAAAATTCTATTTCCATTAATACAGAAACCAATAGCGCAGTTCGCAAATCTTTAGTTAGTTTTACCGAA
CAAGTCGGTGGCTGGTCGGGCCATCCTCGTATTTTCAAAATTGGTAATTTTTACGATGCTTTATATGAAGATTTCAACCT
CACCACTTTCAACCAATTACTTTCAAATCTCAACTTGAGCCCTGACCAACGTGTTAATCAACTTTCTAAAGGGAATTTCC
GCAAGTTAGTAATTGCTGTTACGCTTGCTCGTCAAACTGATTTGTACCTATTAGATGAACCTTTCGACGGGATTGACAGT
ATGACTCGCAAAAAAATCATCTCCAGTATTATTCAATGGAAGCCTGAAAATGCGACGGTTTTAGTCAGCGATCATCATGT
CGGTGATATTGCTAACCTGCTCGATCAAGTCGTCATTATTAAGGACCAACATGTAGCTGCACAAGAGGCCGCAGACACTA
TTCGTGAAACCCTTGGTAAAGATATTGAAACTTACTACGAAGATTTTTATAGAGAGGAGCTTTAA

Upstream 100 bases:

>100_bases
CTTTCTTTAATGTACGATCACCTAGCCAGCCTCCAACTGACCCCAGACGAGATGATTCAAGCATTAACTGAATACGTGAA
CAAGAGAAAGGAAACGCATC

Downstream 100 bases:

>100_bases
GATGACCACTTTCTCACAATTAACGAAAACAATGTTGAAAACCCGAGTAAATCTTATTCATAAGGTCTTTGGCATCTATC
TACTAGTTACCCTAGTCACT

Product: ABC transporter ATPase

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MANLLTINHLSYSRNLQLILKDLNLELPYGQIVGLLGTNGAGKTTLMRLIAGNYIDRKNSISINTETNSAVRKSLVSFTE
QVGGWSGHPRIFKIGNFYDALYEDFNLTTFNQLLSNLNLSPDQRVNQLSKGNFRKLVIAVTLARQTDLYLLDEPFDGIDS
MTRKKIISSIIQWKPENATVLVSDHHVGDIANLLDQVVIIKDQHVAAQEAADTIRETLGKDIETYYEDFYREEL

Sequences:

>Translated_234_residues
MANLLTINHLSYSRNLQLILKDLNLELPYGQIVGLLGTNGAGKTTLMRLIAGNYIDRKNSISINTETNSAVRKSLVSFTE
QVGGWSGHPRIFKIGNFYDALYEDFNLTTFNQLLSNLNLSPDQRVNQLSKGNFRKLVIAVTLARQTDLYLLDEPFDGIDS
MTRKKIISSIIQWKPENATVLVSDHHVGDIANLLDQVVIIKDQHVAAQEAADTIRETLGKDIETYYEDFYREEL
>Mature_233_residues
ANLLTINHLSYSRNLQLILKDLNLELPYGQIVGLLGTNGAGKTTLMRLIAGNYIDRKNSISINTETNSAVRKSLVSFTEQ
VGGWSGHPRIFKIGNFYDALYEDFNLTTFNQLLSNLNLSPDQRVNQLSKGNFRKLVIAVTLARQTDLYLLDEPFDGIDSM
TRKKIISSIIQWKPENATVLVSDHHVGDIANLLDQVVIIKDQHVAAQEAADTIRETLGKDIETYYEDFYREEL

Specific function: Part Of The Abc Transporter Complex Cysawtp Involved In Sulfate/Thiosulfate Import. Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=226, Percent_Identity=27.8761061946903, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI30795238, Length=226, Percent_Identity=27.8761061946903, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI47078218, Length=219, Percent_Identity=27.8538812785388, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI45446740, Length=219, Percent_Identity=27.8538812785388, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI21536376, Length=220, Percent_Identity=24.5454545454545, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150417984, Length=214, Percent_Identity=25.7009345794392, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI116734710, Length=193, Percent_Identity=29.5336787564767, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=28.5046728971963, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786563, Length=202, Percent_Identity=27.2277227722772, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789593, Length=216, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789586, Length=229, Percent_Identity=26.2008733624454, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI2367384, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787089, Length=230, Percent_Identity=26.5217391304348, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787112, Length=211, Percent_Identity=25.5924170616114, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081782, Length=204, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790739, Length=226, Percent_Identity=25.2212389380531, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=189, Percent_Identity=30.6878306878307, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007184, Length=218, Percent_Identity=27.0642201834862, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221500365, Length=218, Percent_Identity=27.0642201834862, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24650853, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650855, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281362751, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574150, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007328, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62484234, Length=219, Percent_Identity=25.5707762557078, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648314, Length=215, Percent_Identity=25.1162790697674, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 26418; Mature: 26287

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00014 ER_TARGET ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLLTINHLSYSRNLQLILKDLNLELPYGQIVGLLGTNGAGKTTLMRLIAGNYIDRKNS
CCCEEEEECCCCCCCHHHHHHHCCCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCCCCCC
ISINTETNSAVRKSLVSFTEQVGGWSGHPRIFKIGNFYDALYEDFNLTTFNQLLSNLNLS
EEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHCCCCHHHHHHHHHCCCC
PDQRVNQLSKGNFRKLVIAVTLARQTDLYLLDEPFDGIDSMTRKKIISSIIQWKPENATV
HHHHHHHHCCCCHHEEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEE
LVSDHHVGDIANLLDQVVIIKDQHVAAQEAADTIRETLGKDIETYYEDFYREEL
EEECCCHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANLLTINHLSYSRNLQLILKDLNLELPYGQIVGLLGTNGAGKTTLMRLIAGNYIDRKNS
CCEEEEECCCCCCCHHHHHHHCCCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCCCCCC
ISINTETNSAVRKSLVSFTEQVGGWSGHPRIFKIGNFYDALYEDFNLTTFNQLLSNLNLS
EEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHCCCCHHHHHHHHHCCCC
PDQRVNQLSKGNFRKLVIAVTLARQTDLYLLDEPFDGIDSMTRKKIISSIIQWKPENATV
HHHHHHHHCCCCHHEEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEE
LVSDHHVGDIANLLDQVVIIKDQHVAAQEAADTIRETLGKDIETYYEDFYREEL
EEECCCHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]