BacMap

Definition	Pediococcus pentosaceus ATCC 25745, complete genome.
Accession	NC_008525
Length	1,832,387

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The map label for this gene is yvgN [H]

Identifier: 116491869

GI number: 116491869

Start: 47214

End: 48080

Strand: Direct

Name: yvgN [H]

Synonym: PEPE_0051

Alternate gene names: 116491869

Gene position: 47214-48080 (Clockwise)

Preceding gene: 116491868

Following gene: 116491873

Centisome position: 2.58

GC content: 38.18

Gene sequence:

>867_bases
ATGAATGTTTTTGAAGAATCGTACAAATTAAGTAATGGTGTAAAAATCCCTAAGTTAGCTTTAGGAACATGGGAAATTGA
TGATGATCAAGTTGCTGACGCTGTGCGCAGCGCAATTGAAATGGGCTATCGTCATATCGATACCGCCCAAGCTTATGCTA
ATGAACGTGGCGTAGGTGAAGGCGTACGTACTGCAAGTGTTCCTCGTGAAGAAATTTTTGTTAACTCAAAAATTGCTGCT
GAAATTAAAAATTATGATGATGCCAAAAAGTCTATTGATGAAACTTTAAACAAAATGGGTCTAGATTATTTGGATATGAT
GATTATTCATAACCCCCAGCCCTGGGCAGAAGTAAATCAATCCGATGATCGTCATTTTGAAGGTAACCTTGAAGTTTGGC
GTGCTCTTGAAGATGCCATGCATGAAGGTAAGCTTCGTGCAATCGGTGTTTCTAGCTTCCAAAAAGAAGACTTGGATAAT
TTAATCAAAAATAGTGATACTAAGCCAATGGTTAACCAAATCTTATCGCATATAGCGGCTACACCAATGGATTTGATTAA
CTACTCTCATGAAAATGGGATTGTGGTTGAAGCATTTTCACCAATCGCTCATGGACAAGCACTTCGTAGCGAAGCTATTC
AAAAAATGGCGGCAAAATATAACGTTAGTGCACCACAATTATCAATCCGTTACGATTGGCAATTAGATACGGTAGTACTT
CCTAAAACTTCTAATCCGGAACACATGAAATCAAACGCCGAGCTTGATTTTGTAATTTCTGATGAAGATATGGAAATTTT
GAAACAAGTCAAACCGCTAGATTACGGGGATGCAAGTGTCTTTCCAGTCTTTGGTGGAAAAATGTAA

Upstream 100 bases:

>100_bases
GCAGTGGCCTTTGTGATTGACACCCCAGCTAATATGGCTGTTAATGAAATGGTAATTCGTCCTACAGGTCAAACCGTTTA
ATTAAAGGAGAAATGATAAT

Downstream 100 bases:

>100_bases
GAGTAATATCAATTTAATCCAAAAAAATAATCTAAGGTTGGTCCTAAAAGGGATCATTCTTAGATTATTTTTTATTATGC
TGTTTTGGGAGTAGCCTGAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: GR; Methylglyoxal reductase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNVFEESYKLSNGVKIPKLALGTWEIDDDQVADAVRSAIEMGYRHIDTAQAYANERGVGEGVRTASVPREEIFVNSKIAA
EIKNYDDAKKSIDETLNKMGLDYLDMMIIHNPQPWAEVNQSDDRHFEGNLEVWRALEDAMHEGKLRAIGVSSFQKEDLDN
LIKNSDTKPMVNQILSHIAATPMDLINYSHENGIVVEAFSPIAHGQALRSEAIQKMAAKYNVSAPQLSIRYDWQLDTVVL
PKTSNPEHMKSNAELDFVISDEDMEILKQVKPLDYGDASVFPVFGGKM

Sequences:

>Translated_288_residues
MNVFEESYKLSNGVKIPKLALGTWEIDDDQVADAVRSAIEMGYRHIDTAQAYANERGVGEGVRTASVPREEIFVNSKIAA
EIKNYDDAKKSIDETLNKMGLDYLDMMIIHNPQPWAEVNQSDDRHFEGNLEVWRALEDAMHEGKLRAIGVSSFQKEDLDN
LIKNSDTKPMVNQILSHIAATPMDLINYSHENGIVVEAFSPIAHGQALRSEAIQKMAAKYNVSAPQLSIRYDWQLDTVVL
PKTSNPEHMKSNAELDFVISDEDMEILKQVKPLDYGDASVFPVFGGKM
>Mature_288_residues
MNVFEESYKLSNGVKIPKLALGTWEIDDDQVADAVRSAIEMGYRHIDTAQAYANERGVGEGVRTASVPREEIFVNSKIAA
EIKNYDDAKKSIDETLNKMGLDYLDMMIIHNPQPWAEVNQSDDRHFEGNLEVWRALEDAMHEGKLRAIGVSSFQKEDLDN
LIKNSDTKPMVNQILSHIAATPMDLINYSHENGIVVEAFSPIAHGQALRSEAIQKMAAKYNVSAPQLSIRYDWQLDTVVL
PKTSNPEHMKSNAELDFVISDEDMEILKQVKPLDYGDASVFPVFGGKM

Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase family [H]

Homologues:

Organism=Homo sapiens, GI223468663, Length=280, Percent_Identity=33.5714285714286, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI24497577, Length=282, Percent_Identity=29.7872340425532, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI5174391, Length=282, Percent_Identity=29.7872340425532, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI4502049, Length=286, Percent_Identity=36.7132867132867, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI291291012, Length=260, Percent_Identity=32.3076923076923, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI5174695, Length=286, Percent_Identity=30.0699300699301, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI93277124, Length=288, Percent_Identity=29.1666666666667, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI300116273, Length=275, Percent_Identity=29.8181818181818, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24497583, Length=299, Percent_Identity=27.0903010033445, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI5453543, Length=294, Percent_Identity=27.2108843537415, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI310109920, Length=294, Percent_Identity=27.2108843537415, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI45446745, Length=294, Percent_Identity=27.2108843537415, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI4503285, Length=294, Percent_Identity=27.2108843537415, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI24497585, Length=288, Percent_Identity=26.0416666666667, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI310109922, Length=281, Percent_Identity=26.3345195729537, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI300116271, Length=276, Percent_Identity=27.1739130434783, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI310109926, Length=114, Percent_Identity=35.0877192982456, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI207028673, Length=114, Percent_Identity=35.0877192982456, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI87082198, Length=273, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786400, Length=268, Percent_Identity=31.3432835820896, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1788081, Length=291, Percent_Identity=27.4914089347079, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564128, Length=295, Percent_Identity=31.1864406779661, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71998625, Length=261, Percent_Identity=36.0153256704981, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17552492, Length=262, Percent_Identity=33.206106870229, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17537075, Length=291, Percent_Identity=31.6151202749141, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17537077, Length=285, Percent_Identity=31.9298245614035, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17561300, Length=268, Percent_Identity=33.955223880597, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17561298, Length=274, Percent_Identity=29.1970802919708, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538386, Length=275, Percent_Identity=30.9090909090909, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17537079, Length=309, Percent_Identity=27.5080906148867, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17566692, Length=290, Percent_Identity=26.551724137931, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17562292, Length=296, Percent_Identity=27.3648648648649, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17550248, Length=296, Percent_Identity=27.027027027027, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322556, Length=273, Percent_Identity=36.6300366300366, Blast_Score=171, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6320576, Length=312, Percent_Identity=32.3717948717949, Blast_Score=159, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324694, Length=281, Percent_Identity=33.4519572953737, Blast_Score=158, Evalue=8e-40,
Organism=Saccharomyces cerevisiae, GI6319625, Length=314, Percent_Identity=32.1656050955414, Blast_Score=154, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321896, Length=296, Percent_Identity=30.0675675675676, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320079, Length=268, Percent_Identity=31.7164179104478, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24657054, Length=285, Percent_Identity=35.4385964912281, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI20129731, Length=291, Percent_Identity=30.9278350515464, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24644950, Length=297, Percent_Identity=29.6296296296296, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24662789, Length=290, Percent_Identity=29.3103448275862, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24663317, Length=283, Percent_Identity=30.0353356890459, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI221378297, Length=317, Percent_Identity=27.7602523659306, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21356425, Length=283, Percent_Identity=31.095406360424, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI45553081, Length=289, Percent_Identity=30.1038062283737, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24662781, Length=275, Percent_Identity=31.2727272727273, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24662785, Length=272, Percent_Identity=30.8823529411765, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281366140, Length=249, Percent_Identity=28.5140562248996, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: =1.1.1.283 [H]

Molecular weight: Translated: 32300; Mature: 32300

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00798 ALDOKETO_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFEESYKLSNGVKIPKLALGTWEIDDDQVADAVRSAIEMGYRHIDTAQAYANERGVGE
CCCCHHHHHHCCCCCCCEEEECEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVRTASVPREEIFVNSKIAAEIKNYDDAKKSIDETLNKMGLDYLDMMIIHNPQPWAEVNQ
CCHHCCCCHHHHEECCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHEEECCCCHHHCCC
SDDRHFEGNLEVWRALEDAMHEGKLRAIGVSSFQKEDLDNLIKNSDTKPMVNQILSHIAA
CCCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
TPMDLINYSHENGIVVEAFSPIAHGQALRSEAIQKMAAKYNVSAPQLSIRYDWQLDTVVL
CCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEE
PKTSNPEHMKSNAELDFVISDEDMEILKQVKPLDYGDASVFPVFGGKM
CCCCCHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MNVFEESYKLSNGVKIPKLALGTWEIDDDQVADAVRSAIEMGYRHIDTAQAYANERGVGE
CCCCHHHHHHCCCCCCCEEEECEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVRTASVPREEIFVNSKIAAEIKNYDDAKKSIDETLNKMGLDYLDMMIIHNPQPWAEVNQ
CCHHCCCCHHHHEECCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHEEECCCCHHHCCC
SDDRHFEGNLEVWRALEDAMHEGKLRAIGVSSFQKEDLDNLIKNSDTKPMVNQILSHIAA
CCCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
TPMDLINYSHENGIVVEAFSPIAHGQALRSEAIQKMAAKYNVSAPQLSIRYDWQLDTVVL
CCHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEE
PKTSNPEHMKSNAELDFVISDEDMEILKQVKPLDYGDASVFPVFGGKM
CCCCCHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]