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The map label for this gene is ykoW [H]

Identifier: 116491853

GI number: 116491853

Start: 33332

End: 34012

Strand: Direct

Name: ykoW [H]

Synonym: PEPE_0035

Alternate gene names: 116491853

Gene position: 33332-34012 (Clockwise)

Preceding gene: 116491851

Following gene: 116491855

Centisome position: 1.82

GC content: 36.71

Gene sequence:

>681_bases
ATGCCTAAGTATCGTTTTTTTGCGCAACAACAAATTAATACAGCAACGAATGCCGTTTTAGGATACGAACTATTAATTAA
GGAGCTAACTCCAGATGGCTGGCGCCTACCAAGTTCATTTATTGATATTGATACAAAAGTTTTTGCTAACTTATTGATAG
AAACAACTAAAATATTAGGCCAAAAGGTTCGCTATTGTTCAGTTAACGTTAACCGTGACCAATTAATGAATACTGATATT
GCAGAAGCAATCATCGAAAGTCAACGTCAACTTTATCCAACCAAGTTAATCGTTGAATTAACCGAAGATGTTAGTGAACG
CGAATACACACCTACAGAAATAAAAGAGCAACTTGAACGCTTTGTCAGCAAAGGAATCCAAATTTCACTTGATGACGTGG
GTACAGGACACAATCAGTTTGAAGATATTGAAGACTTCCTTCCCTTAGCTTCAGAAATTAAATTTGCCGTTCAAAACTTT
AAGTCTACAATTCAAGATCCTAAAATCAAACAAAAGGTCCGTTTCTGGAACGCGATTAGTTCTGAATACAATATTCATTT
GGTATTGGAAGGCATCGAAGACCAAGCAGACAATCAGCTAAGCCAAAGTTTTGGTATTAGCCGCCGCCAAGGTTATTTCT
TCAGTAAACCACAATTACTAAGCCTTCCAGGCGATAAATAA

Upstream 100 bases:

>100_bases
ATTATGAATTATAGTATTTATATAGTATACTATAACTTAAACGTTATACATAGTATAGTATATGATTAATTTTTTTAAAT
TATCGAAGGAGGTATTCTAA

Downstream 100 bases:

>100_bases
AAGTCAAAAAAACTACTAACCTCAAAAGTTAGTAGTTATTTTTTTACAATTTTTTGCTCTAAGATAAGCTTATATAAAAC
GGTTCGAATAGCTATTTCTA

Product: C-di-GMP-specific phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPKYRFFAQQQINTATNAVLGYELLIKELTPDGWRLPSSFIDIDTKVFANLLIETTKILGQKVRYCSVNVNRDQLMNTDI
AEAIIESQRQLYPTKLIVELTEDVSEREYTPTEIKEQLERFVSKGIQISLDDVGTGHNQFEDIEDFLPLASEIKFAVQNF
KSTIQDPKIKQKVRFWNAISSEYNIHLVLEGIEDQADNQLSQSFGISRRQGYFFSKPQLLSLPGDK

Sequences:

>Translated_226_residues
MPKYRFFAQQQINTATNAVLGYELLIKELTPDGWRLPSSFIDIDTKVFANLLIETTKILGQKVRYCSVNVNRDQLMNTDI
AEAIIESQRQLYPTKLIVELTEDVSEREYTPTEIKEQLERFVSKGIQISLDDVGTGHNQFEDIEDFLPLASEIKFAVQNF
KSTIQDPKIKQKVRFWNAISSEYNIHLVLEGIEDQADNQLSQSFGISRRQGYFFSKPQLLSLPGDK
>Mature_225_residues
PKYRFFAQQQINTATNAVLGYELLIKELTPDGWRLPSSFIDIDTKVFANLLIETTKILGQKVRYCSVNVNRDQLMNTDIA
EAIIESQRQLYPTKLIVELTEDVSEREYTPTEIKEQLERFVSKGIQISLDDVGTGHNQFEDIEDFLPLASEIKFAVQNFK
STIQDPKIKQKVRFWNAISSEYNIHLVLEGIEDQADNQLSQSFGISRRQGYFFSKPQLLSLPGDK

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI226510982, Length=229, Percent_Identity=22.707423580786, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081980, Length=238, Percent_Identity=24.3697478991597, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 25986; Mature: 25855

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKYRFFAQQQINTATNAVLGYELLIKELTPDGWRLPSSFIDIDTKVFANLLIETTKILG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QKVRYCSVNVNRDQLMNTDIAEAIIESQRQLYPTKLIVELTEDVSEREYTPTEIKEQLER
HHHHEEEECCCHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FVSKGIQISLDDVGTGHNQFEDIEDFLPLASEIKFAVQNFKSTIQDPKIKQKVRFWNAIS
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
SEYNIHLVLEGIEDQADNQLSQSFGISRRQGYFFSKPQLLSLPGDK
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCEECCCCCC
>Mature Secondary Structure 
PKYRFFAQQQINTATNAVLGYELLIKELTPDGWRLPSSFIDIDTKVFANLLIETTKILG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QKVRYCSVNVNRDQLMNTDIAEAIIESQRQLYPTKLIVELTEDVSEREYTPTEIKEQLER
HHHHEEEECCCHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FVSKGIQISLDDVGTGHNQFEDIEDFLPLASEIKFAVQNFKSTIQDPKIKQKVRFWNAIS
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
SEYNIHLVLEGIEDQADNQLSQSFGISRRQGYFFSKPQLLSLPGDK
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]