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The map label for this gene is sugE [H]

Identifier: 116491850

GI number: 116491850

Start: 30774

End: 31094

Strand: Direct

Name: sugE [H]

Synonym: PEPE_0032

Alternate gene names: 116491850

Gene position: 30774-31094 (Clockwise)

Preceding gene: 116491849

Following gene: 116491851

Centisome position: 1.68

GC content: 37.07

Gene sequence:

>321_bases
ATGACATGGTTTTATTTAGTTTTGGCAGGTATTTTTGAAGTCGTATGGGCAACTACTATGAAGCTCAGCGAAGGATTTAG
TGTTCTAACATATGGAATCGCGACCGCAGTGGGGATGATTATGAGCTTTGTATTTTTATCATTGGCGATTAAACAGATGC
CTCTTAGTTTAGCTTATCCGATTTGGACGGGAATTGGTGCAGTGGGTTCAATCATTGTCGGCGTAATCTTATTTCATGAT
CAAATTCCTAATATTACGTGGGTTTTTATTATAATGTTGATTGTTGGGATTATAGGAATTAAGATGACTGCAGGACATTA
A

Upstream 100 bases:

>100_bases
AAAACGGAAATCACCACCGGGTGGTCAGGCATTTGTAAAGCTCATTAGGTCAATGAAGAGCTTTACGGATGCCTTTTTTA
TTTTTTAGGAGGAATTGAAG

Downstream 100 bases:

>100_bases
AACGGCGGAGGATGTAGGAGTGCAAAAACCTAAAATAGTTATTGATAATTTACCAGAGGAGTCATTTTTTGAGATTTACA
AGGATGAAGACCGGATGCTG

Product: membrane transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTWFYLVLAGIFEVVWATTMKLSEGFSVLTYGIATAVGMIMSFVFLSLAIKQMPLSLAYPIWTGIGAVGSIIVGVILFHD
QIPNITWVFIIMLIVGIIGIKMTAGH

Sequences:

>Translated_106_residues
MTWFYLVLAGIFEVVWATTMKLSEGFSVLTYGIATAVGMIMSFVFLSLAIKQMPLSLAYPIWTGIGAVGSIIVGVILFHD
QIPNITWVFIIMLIVGIIGIKMTAGH
>Mature_105_residues
TWFYLVLAGIFEVVWATTMKLSEGFSVLTYGIATAVGMIMSFVFLSLAIKQMPLSLAYPIWTGIGAVGSIIVGVILFHDQ
IPNITWVFIIMLIVGIIGIKMTAGH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=103, Percent_Identity=41.747572815534, Blast_Score=87, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11568; Mature: 11437

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWFYLVLAGIFEVVWATTMKLSEGFSVLTYGIATAVGMIMSFVFLSLAIKQMPLSLAYP
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IWTGIGAVGSIIVGVILFHDQIPNITWVFIIMLIVGIIGIKMTAGH
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TWFYLVLAGIFEVVWATTMKLSEGFSVLTYGIATAVGMIMSFVFLSLAIKQMPLSLAYP
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IWTGIGAVGSIIVGVILFHDQIPNITWVFIIMLIVGIIGIKMTAGH
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]