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The map label for this gene is alr [H]

Identifier: 116332652

GI number: 116332652

Start: 263807

End: 264946

Strand: Direct

Name: alr [H]

Synonym: LBJ_4232

Alternate gene names: 116332652

Gene position: 263807-264946 (Clockwise)

Preceding gene: 116332645

Following gene: 116332653

Centisome position: 88.01

GC content: 43.51

Gene sequence:

>1140_bases
ATGAAAGAAACTGCCTCTTCCTGGATCGAAATCTCGAAACGTTCTCTGAGTAATAATTTGAATAGTTTTCGTTCCATTTT
ACGCCCGGGTTCGACTCTTACCGCAATCTTAAAATCGAACGCATACGGCCACGGAACGGATTTGATGGCTAAACTCTGCA
TCGAAGAAGGTGTTTCACACATCGGAGTCAACTCGATCGAAGAAGCTCAAAGTATTCGCCAAATCGATCCGAAAATTCCA
ATCCTAATTATGGGAGAAATTCAAAACCCGGAAAAACGGAAAGAAGCTCTCTCCGATCCCAATTTCTGGATCATATTTTC
AAGACCGGAAACGGCTCGAATTCTTTCCTCATTGAACCCCGCCCCAAAACTCCATCTCAAGATCGATACGGGAATGGGTA
GATTGGGAAATCACGGAGAAACCTTAAAATATACATTAGGAGAGTTAAAAAAAAACGGAATTACTCTAGACGGGATCTGT
ACTCATTTTGCAAGTACGGAAGACGTTTTAGAACATAAGTATTCCCTAATGCAAATTCAAAAGTTCGAGAAAGCGGTTTT
ACTCGCGGAGTCCCTCGGTTACAAAAATTTAATCCGACATATGTGCGCTTCCGCTTCCACGATGTTGTTCTCCTCCGCCC
ACTACGAAATGGTAAGAGTGGGAATTTCCTTATATGGGCTCTGGCCGAGCATACAAACCAGACTTTCCTTAAACCTTAAC
GGAAATAAAAATTTCCAACTGAGTCCGATCCTTTCCTGGAAAACACGCATCGTTCACATTCAAAATCATCCTGCCGACAG
TTATATCGGTTACGGTTCCACTTTTCAAACTTCGTATCCTACGAAAGTGGCGATCGTTCCGATCGGTTATTACGAAGGGC
TTGATCGAAAACTTTCGAGTAACGGAGACATGTTGGTTCTTGGCAAAAGAGCGAGGATCATCGGTCGAATCTGTATGAAT
ATGACGATGTTAGACGTTACACATATCTCCGGAGCGGATGTGGGAAGCGTCGTCACGGTCATTGGCCAAGATGGAGAAGA
ATTAATCACGGCGGACGATATTGCGGACCGTACTCATACGATCAATTACGAAATCACGACAAGAATCAGCGAATCCGTTT
GTAGGATTGTGGTAGACTAG

Upstream 100 bases:

>100_bases
TTTTTCAAAACATCCGATTTTCCAATCCAGTAAATAAAAAACTATAGGAAGAATTTGCAAGACATTAATTCTGGTAGGAA
AGTCTTTGGCTTGAAATTCG

Downstream 100 bases:

>100_bases
AAACTCTTTCTTAGTGTAACCTGTATTCGAAAAGAATCCTAAGGCCCGCATGCAAGACGCCATTTCCAAAAATTCAAATA
TAACTCAAATCGTTTATTCC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKETASSWIEISKRSLSNNLNSFRSILRPGSTLTAILKSNAYGHGTDLMAKLCIEEGVSHIGVNSIEEAQSIRQIDPKIP
ILIMGEIQNPEKRKEALSDPNFWIIFSRPETARILSSLNPAPKLHLKIDTGMGRLGNHGETLKYTLGELKKNGITLDGIC
THFASTEDVLEHKYSLMQIQKFEKAVLLAESLGYKNLIRHMCASASTMLFSSAHYEMVRVGISLYGLWPSIQTRLSLNLN
GNKNFQLSPILSWKTRIVHIQNHPADSYIGYGSTFQTSYPTKVAIVPIGYYEGLDRKLSSNGDMLVLGKRARIIGRICMN
MTMLDVTHISGADVGSVVTVIGQDGEELITADDIADRTHTINYEITTRISESVCRIVVD

Sequences:

>Translated_379_residues
MKETASSWIEISKRSLSNNLNSFRSILRPGSTLTAILKSNAYGHGTDLMAKLCIEEGVSHIGVNSIEEAQSIRQIDPKIP
ILIMGEIQNPEKRKEALSDPNFWIIFSRPETARILSSLNPAPKLHLKIDTGMGRLGNHGETLKYTLGELKKNGITLDGIC
THFASTEDVLEHKYSLMQIQKFEKAVLLAESLGYKNLIRHMCASASTMLFSSAHYEMVRVGISLYGLWPSIQTRLSLNLN
GNKNFQLSPILSWKTRIVHIQNHPADSYIGYGSTFQTSYPTKVAIVPIGYYEGLDRKLSSNGDMLVLGKRARIIGRICMN
MTMLDVTHISGADVGSVVTVIGQDGEELITADDIADRTHTINYEITTRISESVCRIVVD
>Mature_379_residues
MKETASSWIEISKRSLSNNLNSFRSILRPGSTLTAILKSNAYGHGTDLMAKLCIEEGVSHIGVNSIEEAQSIRQIDPKIP
ILIMGEIQNPEKRKEALSDPNFWIIFSRPETARILSSLNPAPKLHLKIDTGMGRLGNHGETLKYTLGELKKNGITLDGIC
THFASTEDVLEHKYSLMQIQKFEKAVLLAESLGYKNLIRHMCASASTMLFSSAHYEMVRVGISLYGLWPSIQTRLSLNLN
GNKNFQLSPILSWKTRIVHIQNHPADSYIGYGSTFQTSYPTKVAIVPIGYYEGLDRKLSSNGDMLVLGKRARIIGRICMN
MTMLDVTHISGADVGSVVTVIGQDGEELITADDIADRTHTINYEITTRISESVCRIVVD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=377, Percent_Identity=27.3209549071618, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787439, Length=376, Percent_Identity=25.7978723404255, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42067; Mature: 42067

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETASSWIEISKRSLSNNLNSFRSILRPGSTLTAILKSNAYGHGTDLMAKLCIEEGVSH
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEHHHHCCCCCCCHHHHHHHHHHHCHHH
IGVNSIEEAQSIRQIDPKIPILIMGEIQNPEKRKEALSDPNFWIIFSRPETARILSSLNP
CCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHCCC
APKLHLKIDTGMGRLGNHGETLKYTLGELKKNGITLDGICTHFASTEDVLEHKYSLMQIQ
CCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEHHHHHHHCCHHHHHHHHHHHHHHH
KFEKAVLLAESLGYKNLIRHMCASASTMLFSSAHYEMVRVGISLYGLWPSIQTRLSLNLN
HHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEC
GNKNFQLSPILSWKTRIVHIQNHPADSYIGYGSTFQTSYPTKVAIVPIGYYEGLDRKLSS
CCCCEEEEEEEECCEEEEEEECCCCCCCCCCCCEECCCCCCEEEEEEEHHHHCCCHHHCC
NGDMLVLGKRARIIGRICMNMTMLDVTHISGADVGSVVTVIGQDGEELITADDIADRTHT
CCCEEEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCCEEEHHHHCCCEEE
INYEITTRISESVCRIVVD
EEEEEEEHHHHHHHHEECC
>Mature Secondary Structure
MKETASSWIEISKRSLSNNLNSFRSILRPGSTLTAILKSNAYGHGTDLMAKLCIEEGVSH
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEHHHHCCCCCCCHHHHHHHHHHHCHHH
IGVNSIEEAQSIRQIDPKIPILIMGEIQNPEKRKEALSDPNFWIIFSRPETARILSSLNP
CCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHCCC
APKLHLKIDTGMGRLGNHGETLKYTLGELKKNGITLDGICTHFASTEDVLEHKYSLMQIQ
CCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEHHHHHHHCCHHHHHHHHHHHHHHH
KFEKAVLLAESLGYKNLIRHMCASASTMLFSSAHYEMVRVGISLYGLWPSIQTRLSLNLN
HHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEC
GNKNFQLSPILSWKTRIVHIQNHPADSYIGYGSTFQTSYPTKVAIVPIGYYEGLDRKLSS
CCCCEEEEEEEECCEEEEEEECCCCCCCCCCCCEECCCCCCEEEEEEEHHHHCCCHHHCC
NGDMLVLGKRARIIGRICMNMTMLDVTHISGADVGSVVTVIGQDGEELITADDIADRTHT
CCCEEEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEECCCCCCEEEHHHHCCCEEE
INYEITTRISESVCRIVVD
EEEEEEEHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA