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The map label for this gene is speD

Identifier: 116332650

GI number: 116332650

Start: 261387

End: 261773

Strand: Reverse

Name: speD

Synonym: LBJ_4230

Alternate gene names: 116332650

Gene position: 261773-261387 (Counterclockwise)

Preceding gene: 116332651

Following gene: 116332649

Centisome position: 87.33

GC content: 42.64

Gene sequence:

>387_bases
TTGAACGCATTGGGAAAACATGTAATCGCCGAATTTTATGAATGCGATTATGAAACCATTAACAACCACGAATTAGTTGA
GGACATCATGTTAAAGTCCGTTGACCTGTCAGGTGCCACGACGATTAAGTCGGTTTTTCATAGATTCAGTCCGTATGGAG
TGAGCGGCGTGGTTGTTGTTAGTGAATCCCATTTTGCGATTCATACCTGGCCCGAATACGGTTATTGTGCTGTGGACGTA
TTTACCTGTGGGGATCTTATTGATAATCAGGCAGCCCTGGATTATCTAAAAGAGAAATTTGGCTCGAAAAACGTTTCCGT
TGTGGAAATGAAACGTGGTGTACTGAACTTAGGCGTAGACCTTCATCACAAGCCAGTTGGGAATTAA

Upstream 100 bases:

>100_bases
AAAAAATAAAATAAAATTTACAGTCAGGGTTGACAAAAAAATATAGTAAAAATCATTCTCGATTCTTAATCTAAATGTTT
TTTCTGGAGGTGTCGAGGAG

Downstream 100 bases:

>100_bases
AGTCTCCACCCCAATTATTATAAGCGGATCTATTTCTTCGTTCTTGGGCGGAGAACACCCTTATTTTATAAACTTAGAGA
GGTAAAGACGATGAGTCTGA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MNALGKHVIAEFYECDYETINNHELVEDIMLKSVDLSGATTIKSVFHRFSPYGVSGVVVVSESHFAIHTWPEYGYCAVDV
FTCGDLIDNQAALDYLKEKFGSKNVSVVEMKRGVLNLGVDLHHKPVGN

Sequences:

>Translated_128_residues
MNALGKHVIAEFYECDYETINNHELVEDIMLKSVDLSGATTIKSVFHRFSPYGVSGVVVVSESHFAIHTWPEYGYCAVDV
FTCGDLIDNQAALDYLKEKFGSKNVSVVEMKRGVLNLGVDLHHKPVGN
>Mature_128_residues
MNALGKHVIAEFYECDYETINNHELVEDIMLKSVDLSGATTIKSVFHRFSPYGVSGVVVVSESHFAIHTWPEYGYCAVDV
FTCGDLIDNQAALDYLKEKFGSKNVSVVEMKRGVLNLGVDLHHKPVGN

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_LEPBJ (Q04NB1)

Other databases:

- EMBL:   CP000351
- RefSeq:   YP_802367.1
- ProteinModelPortal:   Q04NB1
- SMR:   Q04NB1
- STRING:   Q04NB1
- GeneID:   4412302
- GenomeReviews:   CP000351_GR
- KEGG:   lbj:LBJ_4230
- eggNOG:   COG1586
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   PRK03124
- BioCyc:   LBOR355277:LBJ_4230-MONOMER
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 14221; Mature: 14221

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALGKHVIAEFYECDYETINNHELVEDIMLKSVDLSGATTIKSVFHRFSPYGVSGVVVV
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEE
SESHFAIHTWPEYGYCAVDVFTCGDLIDNQAALDYLKEKFGSKNVSVVEMKRGVLNLGVD
ECCCEEEEECCCCCEEEEEEEECCHHHCCHHHHHHHHHHHCCCCCEEEHHHCCHHHCCCC
LHHKPVGN
CCCCCCCC
>Mature Secondary Structure
MNALGKHVIAEFYECDYETINNHELVEDIMLKSVDLSGATTIKSVFHRFSPYGVSGVVVV
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEE
SESHFAIHTWPEYGYCAVDVFTCGDLIDNQAALDYLKEKFGSKNVSVVEMKRGVLNLGVD
ECCCEEEEECCCCCEEEEEEEECCHHHCCHHHHHHHHHHHCCCCCEEEHHHCCHHHCCCC
LHHKPVGN
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA