Click here to switch to the map view.

The map label for this gene is pyrF

Identifier: 116332647

GI number: 116332647

Start: 258738

End: 259553

Strand: Reverse

Name: pyrF

Synonym: LBJ_4227

Alternate gene names: 116332647

Gene position: 259553-258738 (Counterclockwise)

Preceding gene: 116332648

Following gene: 116332646

Centisome position: 86.59

GC content: 42.03

Gene sequence:

>816_bases
ATGAATTTTCAAAGTAAGTTCCTAACCCGGAGCCAATCTCTCAAATCCCTTCTTTGTGTCGGACTCGATCCAGACTACTG
CAAACTTCCCGAAATTATTAAACGAAGTCCCGAACCTCTCGTTCATTTCTGTAGAGAGATCATCGACGCGACTGCTCCTT
ATGCGGTCGCATATAAACCGAACATCGCGTTCTTCGAAGTGTTCGGTTCTTCTGGAATTCGTCAGTTTGAAAAAGTGATC
GGACATCTCAAAAATAATTATCCTCAGATTCCCATTGTTGCGGACATCAAACGGGGAGATCTCGATAACACTGCGAGACA
ATATGCGCGTTATTATTTCGGAGACTTGCAGGTGGATAGTTTGACTCTTTCTCCTTATATGGGTCTTGATACTTTACGCC
CTTTTTTAGAATATCAAGATCATCTTGTATTCTGGTTATGTTTAACTTCCAGTCCGGATTCGATTCAGTTTCAAAAGAAA
AGATTTTCGGAAACCGGTCGTACTCTTTATGAAGAAGTTGCATATGTGGCAAATTCGATTTCTCCTTTGAACCTAGGCTT
CGTAGTCGGGGCGACCAATACTTACGAATTAGAAATTCTTCGTAAACAAAATCCAGATCGAATCTTTTTGATTCCCGGTT
TCGGTGCTCAGGGTGCAAAGTTGGATGATCTTTTGCCGGTTTGCGGTCGTTATTCGTTGATTAATTCTTCGAGGGGGATA
CATTTCGCTTCCGACGGTTTGGACTTTGCAGCACGTGCGAATCAAGAAGCCGAAAAGATCCATAATGCAATGCAAGCCAG
ATTTGTCTTTTTATAG

Upstream 100 bases:

>100_bases
GTATTATTCTGCGGAGATGCACAAGGCGGCCTTCGTGCTTCCTCAGTTCGCGCAGAAACATATCGTTCGAAAATAAATTC
TTATATCCGGGGGTGGAACG

Downstream 100 bases:

>100_bases
GGGTTTGGAATGTTATTATAAACCTTCCCATCGTTTCGAAACGCTATTCCACAATAGGATGATTATTTTAACGTGAGTTC
GGCATAAACAAATACGAAAG

Product: orotidine-5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDATAPYAVAYKPNIAFFEVFGSSGIRQFEKVI
GHLKNNYPQIPIVADIKRGDLDNTARQYARYYFGDLQVDSLTLSPYMGLDTLRPFLEYQDHLVFWLCLTSSPDSIQFQKK
RFSETGRTLYEEVAYVANSISPLNLGFVVGATNTYELEILRKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGI
HFASDGLDFAARANQEAEKIHNAMQARFVFL

Sequences:

>Translated_271_residues
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDATAPYAVAYKPNIAFFEVFGSSGIRQFEKVI
GHLKNNYPQIPIVADIKRGDLDNTARQYARYYFGDLQVDSLTLSPYMGLDTLRPFLEYQDHLVFWLCLTSSPDSIQFQKK
RFSETGRTLYEEVAYVANSISPLNLGFVVGATNTYELEILRKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGI
HFASDGLDFAARANQEAEKIHNAMQARFVFL
>Mature_271_residues
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDATAPYAVAYKPNIAFFEVFGSSGIRQFEKVI
GHLKNNYPQIPIVADIKRGDLDNTARQYARYYFGDLQVDSLTLSPYMGLDTLRPFLEYQDHLVFWLCLTSSPDSIQFQKK
RFSETGRTLYEEVAYVANSISPLNLGFVVGATNTYELEILRKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGI
HFASDGLDFAARANQEAEKIHNAMQARFVFL

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_LEPBJ (Q04NB4)

Other databases:

- EMBL:   CP000351
- RefSeq:   YP_802364.1
- ProteinModelPortal:   Q04NB4
- SMR:   Q04NB4
- STRING:   Q04NB4
- GeneID:   4412299
- GenomeReviews:   CP000351_GR
- KEGG:   lbj:LBJ_4227
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   CLSK575422
- BioCyc:   LBOR355277:LBJ_4227-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 30713; Mature: 30713

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 97-97

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDATAPYAVAYKP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEECC
NIAFFEVFGSSGIRQFEKVIGHLKNNYPQIPIVADIKRGDLDNTARQYARYYFGDLQVDS
CEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEE
LTLSPYMGLDTLRPFLEYQDHLVFWLCLTSSPDSIQFQKKRFSETGRTLYEEVAYVANSI
EEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SPLNLGFVVGATNTYELEILRKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGI
CCCEEEEEEECCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHCCCCCC
HFASDGLDFAARANQEAEKIHNAMQARFVFL
EEECCCCCHHHHCCHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDATAPYAVAYKP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEECC
NIAFFEVFGSSGIRQFEKVIGHLKNNYPQIPIVADIKRGDLDNTARQYARYYFGDLQVDS
CEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCEEEEE
LTLSPYMGLDTLRPFLEYQDHLVFWLCLTSSPDSIQFQKKRFSETGRTLYEEVAYVANSI
EEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SPLNLGFVVGATNTYELEILRKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGI
CCCEEEEEEECCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHCCCCCC
HFASDGLDFAARANQEAEKIHNAMQARFVFL
EEECCCCCHHHHCCHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA