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The map label for this gene is htpG [H]

Identifier: 116332491

GI number: 116332491

Start: 52376

End: 54187

Strand: Direct

Name: htpG [H]

Synonym: LBJ_4049

Alternate gene names: 116332491

Gene position: 52376-54187 (Clockwise)

Preceding gene: 116332490

Following gene: 116332492

Centisome position: 17.47

GC content: 41.11

Gene sequence:

>1812_bases
ATGAGCGAAGAAATCAAAGGAAGAATTTCCGTGGAGACGGAAAATATTTTTCCGATTATTAAAAAATGGCTTTATTCCGA
AAAAGATATTTTTATCCGAGAACTGGTATCCAACTCAAGCGACGCGATCACTAAGTTAAAAAAAATAGCGTTCTCCGAGG
AATTCGAAGGAGGTACCGATTATAGAATCGATCTTGAATTCAATCAGGAAAAAAGGATTCTCACGATTGAAGACAACGGA
ATCGGAATGAGTTCCGAAGAGGTTCAAAAATATATCAATCAAATCGCGTTTTCCAGCGCGGAAGAGTTCGTAAAAAAATT
TCAAGGAGAAGGGGCTAAACCTGAAATCATCGGACATTTCGGGCTCGGTTTTTATTCCTGTTTTATGGTTTCTACAAAGG
TAGTTGTAGAAACCAAGTCGTATAAAAAAGGTTCTACCGGAGTAATTTGGGAAAGCGAATCCGGGACCGAATTCTCTTTG
CGTTCTTCGGATAAAACCGCAAGAGGCACTAAAATTACCCTTTATCTCGACGGAGATTCCGGAGAATACCTGGATCAATG
GAAACTCAAGGAATTAGTTCGTAAATACTGCGATTTTTTACCCGTTCCGATTTACGTTAAAAACGAGCAAGCCAACAAAC
AAACTCCTCTTTGGTCCGAAGCACCCTCTTCCGTAACTAAGGAAAAATACGAGGAATTTTACAACTATCTCTTCCCTTTT
TCGGGGGAACCTCTTTTTCACGTTCATTTAAACGTGGACTATCCGTTCCGTCTACAGGGAATATTATACTTTCCTAAATT
AAAACACGAACTGGACGTCAATCAATCCGGAATCAAGCTCTACTGTAATCACGTATTTGTAAGCGACGACGCCAACGATT
TGGTTCCTAAGTTTTTGACCGTACTCAAAGGAACGATCGACATTCCTGATCTGCCTTTGAACGTTTCCCGTTCGTATTTG
CAAAGTGATCCTTTAGTGAAAAAAATCTCCGCCCATATCGTAAAAAAAATCGCGGATCGTTTAAACGAGGAGTTTAAAAA
GAGCGAGGAGGAATTTAGAAAGAACTGGGACGAAATTTCAATTTTCGTAAAGTACGGAATGTTGACCGACGACAAGTTCT
ACGACGCCGCAAAGGATCTTGTATTCTTTAAGACTTCTAACGGGGAGATCGTTCGTCTTGAAGATTATTGGAATAAAAAT
AAGGAGAAGAACAATGGAAAGATATTTTACGCCTTGGAAACTTCCTCCGTATATATGGATTTGCTTAAATCTCAGGGACT
CGAAGCGATTTTAATCGATTCGAGAATTGATTCTCACTTTATTCAATTTTTGGAATCTAAAAATCCGGACATGAAATTTC
AAAGGGCGGATTCGGAACTTGCGGACGGGGTCGTGGATCGGGAACATTCTTCTTCGATTGTCGACTCGAATAACAAGACC
GAGGCGGACCGGATCAAAGAATTTTTTGATAAGATTTTGAAGCGGGACGGACTTGAAATCAAAGCGGAGCCTCTCAAAGC
GGAAGGAGTTCCCGCGGTTGTTCTTCTTCCGGAACATCTCCGCAGACTGAGTGAGATGGGTATGACGGGCAGTCAAAACC
CCCTCGATCTTTTGAAGAACCATACTCTCGTAATCAATACTCGTTCCGTTCTTGTGAAGAATATTTTAGGGATGTCCTCG
ACTAAGGCGGGTAAGTTGGCCCGAACCGTATACGATATGGCCCTTCTTTCTTCTAAAATATTCGGAGAAGCCGAATTCTC
CGAATACTTAAAACGAACTACGGAAACTTTGGAAGAGTTAAGCGCTCCTTAA

Upstream 100 bases:

>100_bases
CCGGTTGTTCGGAATTTGCACTTCGGTTGAATCTCAAGGACAAAAGGACACTGCTTCGTATTGCAAATCGTATTTTAAAA
CATATAAAGGAGAAAGATCT

Downstream 100 bases:

>100_bases
AAAACCCGGAAAAAAGACTTGGAATTTCGAAGTCGATCCGATACATATAGTGTGCGTTTTATGGATCGGCTTCGGATACA
ACTGCTTTTGGTTCTTTTTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSEEIKGRISVETENIFPIIKKWLYSEKDIFIRELVSNSSDAITKLKKIAFSEEFEGGTDYRIDLEFNQEKRILTIEDNG
IGMSSEEVQKYINQIAFSSAEEFVKKFQGEGAKPEIIGHFGLGFYSCFMVSTKVVVETKSYKKGSTGVIWESESGTEFSL
RSSDKTARGTKITLYLDGDSGEYLDQWKLKELVRKYCDFLPVPIYVKNEQANKQTPLWSEAPSSVTKEKYEEFYNYLFPF
SGEPLFHVHLNVDYPFRLQGILYFPKLKHELDVNQSGIKLYCNHVFVSDDANDLVPKFLTVLKGTIDIPDLPLNVSRSYL
QSDPLVKKISAHIVKKIADRLNEEFKKSEEEFRKNWDEISIFVKYGMLTDDKFYDAAKDLVFFKTSNGEIVRLEDYWNKN
KEKNNGKIFYALETSSVYMDLLKSQGLEAILIDSRIDSHFIQFLESKNPDMKFQRADSELADGVVDREHSSSIVDSNNKT
EADRIKEFFDKILKRDGLEIKAEPLKAEGVPAVVLLPEHLRRLSEMGMTGSQNPLDLLKNHTLVINTRSVLVKNILGMSS
TKAGKLARTVYDMALLSSKIFGEAEFSEYLKRTTETLEELSAP

Sequences:

>Translated_603_residues
MSEEIKGRISVETENIFPIIKKWLYSEKDIFIRELVSNSSDAITKLKKIAFSEEFEGGTDYRIDLEFNQEKRILTIEDNG
IGMSSEEVQKYINQIAFSSAEEFVKKFQGEGAKPEIIGHFGLGFYSCFMVSTKVVVETKSYKKGSTGVIWESESGTEFSL
RSSDKTARGTKITLYLDGDSGEYLDQWKLKELVRKYCDFLPVPIYVKNEQANKQTPLWSEAPSSVTKEKYEEFYNYLFPF
SGEPLFHVHLNVDYPFRLQGILYFPKLKHELDVNQSGIKLYCNHVFVSDDANDLVPKFLTVLKGTIDIPDLPLNVSRSYL
QSDPLVKKISAHIVKKIADRLNEEFKKSEEEFRKNWDEISIFVKYGMLTDDKFYDAAKDLVFFKTSNGEIVRLEDYWNKN
KEKNNGKIFYALETSSVYMDLLKSQGLEAILIDSRIDSHFIQFLESKNPDMKFQRADSELADGVVDREHSSSIVDSNNKT
EADRIKEFFDKILKRDGLEIKAEPLKAEGVPAVVLLPEHLRRLSEMGMTGSQNPLDLLKNHTLVINTRSVLVKNILGMSS
TKAGKLARTVYDMALLSSKIFGEAEFSEYLKRTTETLEELSAP
>Mature_602_residues
SEEIKGRISVETENIFPIIKKWLYSEKDIFIRELVSNSSDAITKLKKIAFSEEFEGGTDYRIDLEFNQEKRILTIEDNGI
GMSSEEVQKYINQIAFSSAEEFVKKFQGEGAKPEIIGHFGLGFYSCFMVSTKVVVETKSYKKGSTGVIWESESGTEFSLR
SSDKTARGTKITLYLDGDSGEYLDQWKLKELVRKYCDFLPVPIYVKNEQANKQTPLWSEAPSSVTKEKYEEFYNYLFPFS
GEPLFHVHLNVDYPFRLQGILYFPKLKHELDVNQSGIKLYCNHVFVSDDANDLVPKFLTVLKGTIDIPDLPLNVSRSYLQ
SDPLVKKISAHIVKKIADRLNEEFKKSEEEFRKNWDEISIFVKYGMLTDDKFYDAAKDLVFFKTSNGEIVRLEDYWNKNK
EKNNGKIFYALETSSVYMDLLKSQGLEAILIDSRIDSHFIQFLESKNPDMKFQRADSELADGVVDREHSSSIVDSNNKTE
ADRIKEFFDKILKRDGLEIKAEPLKAEGVPAVVLLPEHLRRLSEMGMTGSQNPLDLLKNHTLVINTRSVLVKNILGMSST
KAGKLARTVYDMALLSSKIFGEAEFSEYLKRTTETLEELSAP

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=614, Percent_Identity=28.3387622149837, Blast_Score=248, Evalue=2e-65,
Organism=Homo sapiens, GI4507677, Length=659, Percent_Identity=27.6176024279211, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI20149594, Length=206, Percent_Identity=35.9223300970874, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI154146191, Length=206, Percent_Identity=36.4077669902913, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI153792590, Length=206, Percent_Identity=36.4077669902913, Blast_Score=133, Evalue=5e-31,
Organism=Escherichia coli, GI1786679, Length=472, Percent_Identity=33.4745762711864, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI115535205, Length=637, Percent_Identity=30.6122448979592, Blast_Score=240, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI115535167, Length=428, Percent_Identity=32.9439252336449, Blast_Score=228, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI17559162, Length=498, Percent_Identity=29.5180722891566, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17542208, Length=521, Percent_Identity=30.5182341650672, Blast_Score=212, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6323840, Length=508, Percent_Identity=30.1181102362205, Blast_Score=213, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6325016, Length=251, Percent_Identity=33.4661354581673, Blast_Score=126, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24586016, Length=448, Percent_Identity=33.2589285714286, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI21357739, Length=506, Percent_Identity=31.4229249011858, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI17647529, Length=198, Percent_Identity=36.8686868686869, Blast_Score=129, Evalue=7e-30,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 69041; Mature: 68910

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEIKGRISVETENIFPIIKKWLYSEKDIFIRELVSNSSDAITKLKKIAFSEEFEGGTD
CCCCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
YRIDLEFNQEKRILTIEDNGIGMSSEEVQKYINQIAFSSAEEFVKKFQGEGAKPEIIGHF
EEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEH
GLGFYSCFMVSTKVVVETKSYKKGSTGVIWESESGTEFSLRSSDKTARGTKITLYLDGDS
HHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEEEECCC
GEYLDQWKLKELVRKYCDFLPVPIYVKNEQANKQTPLWSEAPSSVTKEKYEEFYNYLFPF
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
SGEPLFHVHLNVDYPFRLQGILYFPKLKHELDVNQSGIKLYCNHVFVSDDANDLVPKFLT
CCCCEEEEEEECCCCEEEEEEEECCCHHHHCCCCCCCEEEEEEEEEEECCHHHHHHHHHH
VLKGTIDIPDLPLNVSRSYLQSDPLVKKISAHIVKKIADRLNEEFKKSEEEFRKNWDEIS
HHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
IFVKYGMLTDDKFYDAAKDLVFFKTSNGEIVRLEDYWNKNKEKNNGKIFYALETSSVYMD
EEEEECCCCCCHHHHHHCCEEEEECCCCCEEEEHHHCCCCCCCCCCEEEEEEECHHHHHH
LLKSQGLEAILIDSRIDSHFIQFLESKNPDMKFQRADSELADGVVDREHSSSIVDSNNKT
HHHHCCCEEEEEECHHHHHHHHHHHCCCCCCEEECCCHHHHCCHHCCCCCCCCCCCCCCC
EADRIKEFFDKILKRDGLEIKAEPLKAEGVPAVVLLPEHLRRLSEMGMTGSQNPLDLLKN
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECHHHHHHHHHCCCCCCCCHHHHHHC
HTLVINTRSVLVKNILGMSSTKAGKLARTVYDMALLSSKIFGEAEFSEYLKRTTETLEEL
CEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SAP
CCC
>Mature Secondary Structure 
SEEIKGRISVETENIFPIIKKWLYSEKDIFIRELVSNSSDAITKLKKIAFSEEFEGGTD
CCCCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
YRIDLEFNQEKRILTIEDNGIGMSSEEVQKYINQIAFSSAEEFVKKFQGEGAKPEIIGHF
EEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEH
GLGFYSCFMVSTKVVVETKSYKKGSTGVIWESESGTEFSLRSSDKTARGTKITLYLDGDS
HHHHHHHHHHHHEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEEEECCC
GEYLDQWKLKELVRKYCDFLPVPIYVKNEQANKQTPLWSEAPSSVTKEKYEEFYNYLFPF
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
SGEPLFHVHLNVDYPFRLQGILYFPKLKHELDVNQSGIKLYCNHVFVSDDANDLVPKFLT
CCCCEEEEEEECCCCEEEEEEEECCCHHHHCCCCCCCEEEEEEEEEEECCHHHHHHHHHH
VLKGTIDIPDLPLNVSRSYLQSDPLVKKISAHIVKKIADRLNEEFKKSEEEFRKNWDEIS
HHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEE
IFVKYGMLTDDKFYDAAKDLVFFKTSNGEIVRLEDYWNKNKEKNNGKIFYALETSSVYMD
EEEEECCCCCCHHHHHHCCEEEEECCCCCEEEEHHHCCCCCCCCCCEEEEEEECHHHHHH
LLKSQGLEAILIDSRIDSHFIQFLESKNPDMKFQRADSELADGVVDREHSSSIVDSNNKT
HHHHCCCEEEEEECHHHHHHHHHHHCCCCCCEEECCCHHHHCCHHCCCCCCCCCCCCCCC
EADRIKEFFDKILKRDGLEIKAEPLKAEGVPAVVLLPEHLRRLSEMGMTGSQNPLDLLKN
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECHHHHHHHHHCCCCCCCCHHHHHHC
HTLVINTRSVLVKNILGMSSTKAGKLARTVYDMALLSSKIFGEAEFSEYLKRTTETLEEL
CEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SAP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10722592 [H]