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The map label for this gene is pkn1 [H]

Identifier: 116329319

GI number: 116329319

Start: 3268707

End: 3269588

Strand: Direct

Name: pkn1 [H]

Synonym: LBL_2765

Alternate gene names: 116329319

Gene position: 3268707-3269588 (Clockwise)

Preceding gene: 116329316

Following gene: 116329320

Centisome position: 90.43

GC content: 46.6

Gene sequence:

>882_bases
ATGAAACCGAAAATTCGAAATATCCTTCTACTCGCAATGTTTTCGACCGCTTGTTTAGAATGTACATACAAATTGTTTGC
GGACTCCCTTCCCTGCGGTGGTAAAGAAATCGCCGGAATGAAATGTATTCCTGCCGGAGAATTCATACGAGGAAGTAACA
CGTACGACGCGGACGAGAAGCCGGAAGAGAAAATTTATGTGAGTGACTTTTATATGGACATATATGAAGTCACGAACGAA
GAATTTGATAAATGCAAAATTGCGGGCAAATGCCAAGAATGTTTAAAAGCGGGTAAGTGTAATTACATCGGACCACGTTA
TGGTAAACCCTACTTAGGTCCCAAACAACCCGCAGTAGGAATCAGCTGGTATACGGCAAAAGAATTCTGTGAATGGGCAG
GCAAGAGACTTCCAACGGAAGCAGAATGGGAAAAAGCGGCCAGAGGACCCGATGGAAATTTATATCCTTGGGGAAACGAA
CCCGCAACCTGCGAAAAAGCGATCATCGCGGTGGGAGACATCAAAGGATGTGTCGCTAAAAAAACGGAAAAACCCCATCT
TATGCCGACGGCCGACGTCGGAACAAAAGCCCCCGGAGTCTACGGTTTGTACGATATGGCCGGTAATTCATGGGAATGGA
CCGCAGATTGGTATTCCCCTTCTTTTAAAGTTTGCGGGGACGCCTGTAGAGGAAAAAACCCAAAAGGTCCTTGCGGTGGA
AAAGGATCCTGTCCGGGTTACTCGAAGAAAGTCTTAAAAAGCGGCTCTTGGTGGTGGCCGGCAAGTTATGCAAGAGGCTC
CAAAAGGAGAGCCCACATTCCGGAAAACTTTCCGGAATACCATCATTTCGGTTTTCGCTGCGCAAAGGACGCAGACAATT
AA

Upstream 100 bases:

>100_bases
GAGATTTTTTAAAATACTTGATTTGTTTGTTTCCTTTTTCAGTCTATCCTCATTCTAAAAGCTCCTTTCTACTATGGAGT
CCTTTAGGATAGGAATCTTT

Downstream 100 bases:

>100_bases
TATGATCAATAATAGTAAATTAGAAATTTATTCCATTCTTATGCTCTCGACTCTCTGTTTTTCGTCTTGCTTCGGATCGA
AAAAAACCGAAGAAAGTCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKPKIRNILLLAMFSTACLECTYKLFADSLPCGGKEIAGMKCIPAGEFIRGSNTYDADEKPEEKIYVSDFYMDIYEVTNE
EFDKCKIAGKCQECLKAGKCNYIGPRYGKPYLGPKQPAVGISWYTAKEFCEWAGKRLPTEAEWEKAARGPDGNLYPWGNE
PATCEKAIIAVGDIKGCVAKKTEKPHLMPTADVGTKAPGVYGLYDMAGNSWEWTADWYSPSFKVCGDACRGKNPKGPCGG
KGSCPGYSKKVLKSGSWWWPASYARGSKRRAHIPENFPEYHHFGFRCAKDADN

Sequences:

>Translated_293_residues
MKPKIRNILLLAMFSTACLECTYKLFADSLPCGGKEIAGMKCIPAGEFIRGSNTYDADEKPEEKIYVSDFYMDIYEVTNE
EFDKCKIAGKCQECLKAGKCNYIGPRYGKPYLGPKQPAVGISWYTAKEFCEWAGKRLPTEAEWEKAARGPDGNLYPWGNE
PATCEKAIIAVGDIKGCVAKKTEKPHLMPTADVGTKAPGVYGLYDMAGNSWEWTADWYSPSFKVCGDACRGKNPKGPCGG
KGSCPGYSKKVLKSGSWWWPASYARGSKRRAHIPENFPEYHHFGFRCAKDADN
>Mature_293_residues
MKPKIRNILLLAMFSTACLECTYKLFADSLPCGGKEIAGMKCIPAGEFIRGSNTYDADEKPEEKIYVSDFYMDIYEVTNE
EFDKCKIAGKCQECLKAGKCNYIGPRYGKPYLGPKQPAVGISWYTAKEFCEWAGKRLPTEAEWEKAARGPDGNLYPWGNE
PATCEKAIIAVGDIKGCVAKKTEKPHLMPTADVGTKAPGVYGLYDMAGNSWEWTADWYSPSFKVCGDACRGKNPKGPCGG
KGSCPGYSKKVLKSGSWWWPASYARGSKRRAHIPENFPEYHHFGFRCAKDADN

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=269, Percent_Identity=35.6877323420074, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI38202250, Length=294, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI257470977, Length=225, Percent_Identity=33.7777777777778, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI194248087, Length=293, Percent_Identity=28.3276450511945, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20130397, Length=223, Percent_Identity=33.1838565022422, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32506; Mature: 32506

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKIRNILLLAMFSTACLECTYKLFADSLPCGGKEIAGMKCIPAGEFIRGSNTYDADEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCC
PEEKIYVSDFYMDIYEVTNEEFDKCKIAGKCQECLKAGKCNYIGPRYGKPYLGPKQPAVG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
ISWYTAKEFCEWAGKRLPTEAEWEKAARGPDGNLYPWGNEPATCEKAIIAVGDIKGCVAK
EEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEEECCHHHHHHC
KTEKPHLMPTADVGTKAPGVYGLYDMAGNSWEWTADWYSPSFKVCGDACRGKNPKGPCGG
CCCCCCCCCCCCCCCCCCCCEEHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCC
KGSCPGYSKKVLKSGSWWWPASYARGSKRRAHIPENFPEYHHFGFRCAKDADN
CCCCCCHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCCEECCCCCC
>Mature Secondary Structure
MKPKIRNILLLAMFSTACLECTYKLFADSLPCGGKEIAGMKCIPAGEFIRGSNTYDADEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCC
PEEKIYVSDFYMDIYEVTNEEFDKCKIAGKCQECLKAGKCNYIGPRYGKPYLGPKQPAVG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
ISWYTAKEFCEWAGKRLPTEAEWEKAARGPDGNLYPWGNEPATCEKAIIAVGDIKGCVAK
EEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEEECCHHHHHHC
KTEKPHLMPTADVGTKAPGVYGLYDMAGNSWEWTADWYSPSFKVCGDACRGKNPKGPCGG
CCCCCCCCCCCCCCCCCCCCEEHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCC
KGSCPGYSKKVLKSGSWWWPASYARGSKRRAHIPENFPEYHHFGFRCAKDADN
CCCCCCHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]