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The map label for this gene is arnC [H]

Identifier: 116329274

GI number: 116329274

Start: 3216655

End: 3217350

Strand: Direct

Name: arnC [H]

Synonym: LBL_2716

Alternate gene names: 116329274

Gene position: 3216655-3217350 (Clockwise)

Preceding gene: 116329273

Following gene: 116329275

Centisome position: 88.99

GC content: 40.23

Gene sequence:

>696_bases
ATGAAAGTTTCCATCGTCATTCCTTGTTATAACGAGAAAAATACGATCCGTAATATTCTGGAAACGGTTAAGAAAGTTCC
GATCAAAAACAAAGAAATCATTCTCGTGGACGACTGTTCCAAAGATGGAACAAGAGATCTTCTTCAAACCCCGGCTATTA
AAAAATTAACTAATCAAATCATCTTTCACGAAGTCAATTATGGAAAAGGGGCCGCCCTTAGAACGGGTTTTAAAGCCGCA
ACCGGAGATATTGTAATCGTTCAAGACGCAGATTTGGAATACGACCCTTTTGAAATTCCGGAAGTTATCGATCCGATTTA
CAAAGGCAAAGCGGACGTGGTATTCGGAAGCAGATTCTTGAGCGGACGTCCTCATAGAGTTGTTTATTACTGGCATCGTC
TGGGAAATATGGTGCTAACAACCCTTTCCAACATGTTCACCAATATCAACTTAACGGACATGGAAACTTGTTATAAAGCA
TTTCGTAGAGAAATTATCCAGTCCATCGATATCAAAGAAAATCGTTTCGGCTTCGAACCGGAAATCACCGCAAAGGTCGC
TAAAATTCCGGATGTTCGTATCTTTGAAGTAGGCATTTCCTATTACGGAAGAACTTACGCGGAAGGGAAAAAAATCGGTT
GGAAAGACGGTTTTCGCGCGATTTATTGCATTCTTCGTTATAACTTATTCGACTGA

Upstream 100 bases:

>100_bases
AGAATTTGGTTTTCGGAATCGCTCTTGAAAAAATAATAGTACGAGCTGATACAATTATTCGGGACTTCCGAATGGCCGAA
ATCACAGGTCTGGAGTTAAC

Downstream 100 bases:

>100_bases
GGTATGATATTACGTTTGAATGATGGGAATTTCCCATAATTTTAAGATTTTGAATCGAATCACCCGACCTTAAAAGCCTG
TTCAAATTTTTAAAATCAAT

Product: glycosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKVSIVIPCYNEKNTIRNILETVKKVPIKNKEIILVDDCSKDGTRDLLQTPAIKKLTNQIIFHEVNYGKGAALRTGFKAA
TGDIVIVQDADLEYDPFEIPEVIDPIYKGKADVVFGSRFLSGRPHRVVYYWHRLGNMVLTTLSNMFTNINLTDMETCYKA
FRREIIQSIDIKENRFGFEPEITAKVAKIPDVRIFEVGISYYGRTYAEGKKIGWKDGFRAIYCILRYNLFD

Sequences:

>Translated_231_residues
MKVSIVIPCYNEKNTIRNILETVKKVPIKNKEIILVDDCSKDGTRDLLQTPAIKKLTNQIIFHEVNYGKGAALRTGFKAA
TGDIVIVQDADLEYDPFEIPEVIDPIYKGKADVVFGSRFLSGRPHRVVYYWHRLGNMVLTTLSNMFTNINLTDMETCYKA
FRREIIQSIDIKENRFGFEPEITAKVAKIPDVRIFEVGISYYGRTYAEGKKIGWKDGFRAIYCILRYNLFD
>Mature_231_residues
MKVSIVIPCYNEKNTIRNILETVKKVPIKNKEIILVDDCSKDGTRDLLQTPAIKKLTNQIIFHEVNYGKGAALRTGFKAA
TGDIVIVQDADLEYDPFEIPEVIDPIYKGKADVVFGSRFLSGRPHRVVYYWHRLGNMVLTTLSNMFTNINLTDMETCYKA
FRREIIQSIDIKENRFGFEPEITAKVAKIPDVRIFEVGISYYGRTYAEGKKIGWKDGFRAIYCILRYNLFD

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=220, Percent_Identity=30.9090909090909, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788588, Length=213, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788692, Length=237, Percent_Identity=27.4261603375527, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71999402, Length=220, Percent_Identity=29.0909090909091, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24585265, Length=219, Percent_Identity=27.3972602739726, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 26562; Mature: 26562

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSIVIPCYNEKNTIRNILETVKKVPIKNKEIILVDDCSKDGTRDLLQTPAIKKLTNQI
CEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHHH
IFHEVNYGKGAALRTGFKAATGDIVIVQDADLEYDPFEIPEVIDPIYKGKADVVFGSRFL
EEEECCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEECHHHH
SGRPHRVVYYWHRLGNMVLTTLSNMFTNINLTDMETCYKAFRREIIQSIDIKENRFGFEP
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EITAKVAKIPDVRIFEVGISYYGRTYAEGKKIGWKDGFRAIYCILRYNLFD
CHHHHHHCCCCEEEEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVSIVIPCYNEKNTIRNILETVKKVPIKNKEIILVDDCSKDGTRDLLQTPAIKKLTNQI
CEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCHHHHHHHHH
IFHEVNYGKGAALRTGFKAATGDIVIVQDADLEYDPFEIPEVIDPIYKGKADVVFGSRFL
EEEECCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCEEECHHHH
SGRPHRVVYYWHRLGNMVLTTLSNMFTNINLTDMETCYKAFRREIIQSIDIKENRFGFEP
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EITAKVAKIPDVRIFEVGISYYGRTYAEGKKIGWKDGFRAIYCILRYNLFD
CHHHHHHCCCCEEEEEECHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA