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The map label for this gene is crp [C]

Identifier: 116329261

GI number: 116329261

Start: 3201092

End: 3201757

Strand: Direct

Name: crp [C]

Synonym: LBL_2700

Alternate gene names: 116329261

Gene position: 3201092-3201757 (Clockwise)

Preceding gene: 116329260

Following gene: 116329263

Centisome position: 88.56

GC content: 40.99

Gene sequence:

>666_bases
ATGGATATGATGCTCGAAACTATGTTCTCTAAATTCGGTCAGACGTACGAGCCGAATCAGATTATCTTTTGCGAAAACGA
GCCCGGAAATAATTTTTATCTGATCCAGTCTGGCAAAGTGAAGATCGTAAAAACGGTCCCGAATCCGACTAAGAAAGAAG
ATCATTTGATCAAAACTCTCGATATCCTCGAACAAGGGGACATTTTCGGAGAAATGGCGATCCTGGAAGAACAACCTAGA
TCCGCGACTGCGATCGCAATCTCAGAAGTGAAAGTATTGAACTTCAACCGTACAAACTTTGAACTTTTAATGACTAAAAA
CCCCATGTTGGCGATGAAAATTCTCACGATTTTTTCGGTCCGAATCAATGACGCTAAAAGAAGGCTTTTGATACTTCTAA
TGGACGACATTCAAGGAAAGGTTGCCGACGTATTCCTAATGCTCTATGAAAAGATGCACGCGCATAGTGATTTCAAAGAA
ATCGTTTTGAATGTTTCTCAACACGACGTGGCGGAATGGTGTGCCCAACCGGTAGGCGAGGTGCAAAAGGTCCTAAATAC
TCTTTCCAAAAGCGGTAAAATCGAACTTTACGAAGATAAAATTGTTATACACAACATCGCCGACTTCCAGAGAATAGTCT
CACAAAAACGGAAACCAAATTCTTAA

Upstream 100 bases:

>100_bases
AAAGAGCGAGAATGTTATACGGTAAAGTCGCGCTTCTACCTCCCGAAAAAGACAGCCTCTCCCAAAAATCCAGGTTAAAA
GCCAAGGAAATGGGAATCTG

Downstream 100 bases:

>100_bases
ACGCTCCCGTAGCTCAGGTGGACAGAGCAGAAGTTTCCTAAACTTTTGGTCGGAGGTTCGAATCCTCTCGGGGGCGCCAA
TCTAATGCTGATGAAGGAAT

Product: cAMP-binding protein, regulatory protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulatory Protein; Catabolite Gene Activator; Transcription Regulator; Transcriptional Regulator Crp/Fnr Family Protein; Cyclic AMP Receptor Protein; CRP Family Transcriptional Regulator; Catabolite Gene Activator Protein; Transcriptional Regulator Crp; FNR/CAP Family Transcriptional Regulator; CAMP Receptor Protein; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDMMLETMFSKFGQTYEPNQIIFCENEPGNNFYLIQSGKVKIVKTVPNPTKKEDHLIKTLDILEQGDIFGEMAILEEQPR
SATAIAISEVKVLNFNRTNFELLMTKNPMLAMKILTIFSVRINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKE
IVLNVSQHDVAEWCAQPVGEVQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVSQKRKPNS

Sequences:

>Translated_221_residues
MDMMLETMFSKFGQTYEPNQIIFCENEPGNNFYLIQSGKVKIVKTVPNPTKKEDHLIKTLDILEQGDIFGEMAILEEQPR
SATAIAISEVKVLNFNRTNFELLMTKNPMLAMKILTIFSVRINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKE
IVLNVSQHDVAEWCAQPVGEVQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVSQKRKPNS
>Mature_221_residues
MDMMLETMFSKFGQTYEPNQIIFCENEPGNNFYLIQSGKVKIVKTVPNPTKKEDHLIKTLDILEQGDIFGEMAILEEQPR
SATAIAISEVKVLNFNRTNFELLMTKNPMLAMKILTIFSVRINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKE
IVLNVSQHDVAEWCAQPVGEVQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVSQKRKPNS

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25374; Mature: 25374

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMMLETMFSKFGQTYEPNQIIFCENEPGNNFYLIQSGKVKIVKTVPNPTKKEDHLIKTL
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHH
DILEQGDIFGEMAILEEQPRSATAIAISEVKVLNFNRTNFELLMTKNPMLAMKILTIFSV
HHHHCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHE
RINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKEIVLNVSQHDVAEWCAQPVGE
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHH
VQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVSQKRKPNS
HHHHHHHHHCCCCEEEEECEEEEECHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDMMLETMFSKFGQTYEPNQIIFCENEPGNNFYLIQSGKVKIVKTVPNPTKKEDHLIKTL
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHH
DILEQGDIFGEMAILEEQPRSATAIAISEVKVLNFNRTNFELLMTKNPMLAMKILTIFSV
HHHHCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHE
RINDAKRRLLILLMDDIQGKVADVFLMLYEKMHAHSDFKEIVLNVSQHDVAEWCAQPVGE
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCHHH
VQKVLNTLSKSGKIELYEDKIVIHNIADFQRIVSQKRKPNS
HHHHHHHHHCCCCEEEEECEEEEECHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA