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The map label for this gene is galE [H]

Identifier: 116329232

GI number: 116329232

Start: 3163793

End: 3164764

Strand: Direct

Name: galE [H]

Synonym: LBL_2670

Alternate gene names: 116329232

Gene position: 3163793-3164764 (Clockwise)

Preceding gene: 116329231

Following gene: 116329234

Centisome position: 87.53

GC content: 43.72

Gene sequence:

>972_bases
GTGAGATTACTAATTACGGGGGGTGCAGGTTACATCGGAAGTCATATAGTCGCACTTCTTCTTGAAAAAAAGCACGAAAT
TTTAATCGTAGATAATCTTGAAAAAGGAAATGAAGCAAATCTTTTTTCGGGACCGGAACTGATTCAAGGAAATATCCAGG
ACGACTTCGTTTTAGAAAAAGCATTTTCAAAGCCGATCGACGCAGTCTTTCATTTCGCCGCGTGGAAAGCGGCGGGCGAA
TCGATGACAAATCCTTCCAAATATGCTCTGAACAACATCAACGGAACTCTTAAACTTCTTACTTATATGGAAAAGGCGGG
GACCAAAAAATTCATCTTTTCCTCATCCGCGGCGGTTTACGGTTCTCCCCAATATCTTCCCATCGACGAAAAACATCCGG
TTCATCCGGAAAATTATTACGGTTATACGAAGCTCGCGATCGAACAGAACCTGAAGTGGTACGAGTCTCTCAAAGGATTC
AATTTTGCTGCATTACGTTATTTTAATGCGGCAGGTTACGATCCCGAAGGAAGAGTTCGGGGTCTGGAAAAAACTCCCGC
AAACCTTCTTCCGATCATCATGGAAACTGCGGCGGGTATGAGAAACGAATTCGAAGTATTCGGGACCGATTACGAAACTC
CGGACGGAAGTTGTATCCGTGATTATATTCACGTAACCGACTTAGCAAAGGCCCATGTTCTAAGCCTTGAGTATCTCGAT
TCCGAAAAAAAATCTCTCACGGTTAACTTAGGGTCCGAAAAGGGTTATTCGGTTTTGGAAGTGATTCGTCTTGCAGAGGA
AGTGGTTGGAAGACAAATCTCTCATAAAATTTCTGGGAGAAGAGCGGGAGATCCCGCAAAACTTTTGGCTTCTTCGGCAA
CGGCTCAACGTTTATTGAAATGGGCTCCGGAATATAGCGAGGCCAAAACTCTTCTCAAAACGATGTGGAACGTATATCAA
AATCCGGCTTAA

Upstream 100 bases:

>100_bases
AAGCCTTGGATGAGCTGGAGGTTTCGAGCGACCCGATCGAGGAAGTAAAGTATATTATAAAATTCTTTAGAGATAGCGAT
AGAGGAGTGACAAGCCACAG

Downstream 100 bases:

>100_bases
AATAAATCACCGAATCGATCTACACTCCGGATTTACGGAAGTCACGTATTCAAAAGAGAGGTCTTGTAAGAATTCTCCTC
CTGAAAATTTTTCTTTGAAT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRLLITGGAGYIGSHIVALLLEKKHEILIVDNLEKGNEANLFSGPELIQGNIQDDFVLEKAFSKPIDAVFHFAAWKAAGE
SMTNPSKYALNNINGTLKLLTYMEKAGTKKFIFSSSAAVYGSPQYLPIDEKHPVHPENYYGYTKLAIEQNLKWYESLKGF
NFAALRYFNAAGYDPEGRVRGLEKTPANLLPIIMETAAGMRNEFEVFGTDYETPDGSCIRDYIHVTDLAKAHVLSLEYLD
SEKKSLTVNLGSEKGYSVLEVIRLAEEVVGRQISHKISGRRAGDPAKLLASSATAQRLLKWAPEYSEAKTLLKTMWNVYQ
NPA

Sequences:

>Translated_323_residues
MRLLITGGAGYIGSHIVALLLEKKHEILIVDNLEKGNEANLFSGPELIQGNIQDDFVLEKAFSKPIDAVFHFAAWKAAGE
SMTNPSKYALNNINGTLKLLTYMEKAGTKKFIFSSSAAVYGSPQYLPIDEKHPVHPENYYGYTKLAIEQNLKWYESLKGF
NFAALRYFNAAGYDPEGRVRGLEKTPANLLPIIMETAAGMRNEFEVFGTDYETPDGSCIRDYIHVTDLAKAHVLSLEYLD
SEKKSLTVNLGSEKGYSVLEVIRLAEEVVGRQISHKISGRRAGDPAKLLASSATAQRLLKWAPEYSEAKTLLKTMWNVYQ
NPA
>Mature_323_residues
MRLLITGGAGYIGSHIVALLLEKKHEILIVDNLEKGNEANLFSGPELIQGNIQDDFVLEKAFSKPIDAVFHFAAWKAAGE
SMTNPSKYALNNINGTLKLLTYMEKAGTKKFIFSSSAAVYGSPQYLPIDEKHPVHPENYYGYTKLAIEQNLKWYESLKGF
NFAALRYFNAAGYDPEGRVRGLEKTPANLLPIIMETAAGMRNEFEVFGTDYETPDGSCIRDYIHVTDLAKAHVLSLEYLD
SEKKSLTVNLGSEKGYSVLEVIRLAEEVVGRQISHKISGRRAGDPAKLLASSATAQRLLKWAPEYSEAKTLLKTMWNVYQ
NPA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=38.5507246376812, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=38.5507246376812, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=38.5507246376812, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=27.6190476190476, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=27.6978417266187, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786974, Length=312, Percent_Identity=39.7435897435897, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1790049, Length=248, Percent_Identity=28.2258064516129, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=337, Percent_Identity=36.7952522255193, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI71982038, Length=339, Percent_Identity=36.5781710914454, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17539532, Length=335, Percent_Identity=25.3731343283582, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319493, Length=340, Percent_Identity=41.4705882352941, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=37.5, Blast_Score=200, Evalue=9e-52,
Organism=Drosophila melanogaster, GI21356223, Length=328, Percent_Identity=27.1341463414634, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35946; Mature: 35946

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLITGGAGYIGSHIVALLLEKKHEILIVDNLEKGNEANLFSGPELIQGNIQDDFVLEK
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHH
AFSKPIDAVFHFAAWKAAGESMTNPSKYALNNINGTLKLLTYMEKAGTKKFIFSSSAAVY
HHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCEEC
GSPQYLPIDEKHPVHPENYYGYTKLAIEQNLKWYESLKGFNFAALRYFNAAGYDPEGRVR
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCHHHHHHCCCCCHHHEEECCCCCCCCCCCC
GLEKTPANLLPIIMETAAGMRNEFEVFGTDYETPDGSCIRDYIHVTDLAKAHVLSLEYLD
CCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SEKKSLTVNLGSEKGYSVLEVIRLAEEVVGRQISHKISGRRAGDPAKLLASSATAQRLLK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
WAPEYSEAKTLLKTMWNVYQNPA
HCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLLITGGAGYIGSHIVALLLEKKHEILIVDNLEKGNEANLFSGPELIQGNIQDDFVLEK
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHH
AFSKPIDAVFHFAAWKAAGESMTNPSKYALNNINGTLKLLTYMEKAGTKKFIFSSSAAVY
HHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCEEC
GSPQYLPIDEKHPVHPENYYGYTKLAIEQNLKWYESLKGFNFAALRYFNAAGYDPEGRVR
CCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCHHHHHHCCCCCHHHEEECCCCCCCCCCCC
GLEKTPANLLPIIMETAAGMRNEFEVFGTDYETPDGSCIRDYIHVTDLAKAHVLSLEYLD
CCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SEKKSLTVNLGSEKGYSVLEVIRLAEEVVGRQISHKISGRRAGDPAKLLASSATAQRLLK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
WAPEYSEAKTLLKTMWNVYQNPA
HCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]