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The map label for this gene is mraY

Identifier: 116329174

GI number: 116329174

Start: 3076286

End: 3077398

Strand: Direct

Name: mraY

Synonym: LBL_2601

Alternate gene names: 116329174

Gene position: 3076286-3077398 (Clockwise)

Preceding gene: 116329173

Following gene: 116329175

Centisome position: 85.11

GC content: 42.77

Gene sequence:

>1113_bases
ATGTTTTATTATCTATACGATCTTTACTTTAACCATCTCGATTCTCTTAGAATTTTCAGCTACGTTACATTTCGCGCTTT
GATGGCGGGTTTGACCTCTATGTTCGTCACATTTTGGCTCGGGCATAAAGTGATCGACTTTCTGTACGGACTCAAATTCC
GGGAATCGGTTCGAGACGACGGTCCCAAGTCTCACGAATCAAAAAAAGGAACTCCGACCATGGGCGGACTCTTGATTATC
GGCTCTCTGCTTCTTTCCGTTTTACTTTGGGGCAATTTAAAAAATTCGAATATAATCGTATTATCCGTATTTGCACTTTG
TTTTTCCGCACTCGGTTTTGCGGACGATTACATGAAATCCGTAAAAAAAATCAAGGGAGGAATGAAGGCAAGAACCAAGT
TTCTTTTATCGATTTTGATCTCTTTAGTTTTTTGTATATTATTTTTTTATTATACAGGTGTGATTCCGACCGGACATTCC
GGTAAAATTCCGTTTCAGATCACGGATCTATTTTTTCCATTCGTCAAAGGTCCCGTGTTAGCATTAGGCGTTTTTGCAAT
TCCTTTTTCGATTCTTGTGATTATTGGTTCCTCCCACGCCGTAAATTTAACGGACGGGCTAGACGGACTTGCTACCGGAA
CCGTCGCGATCTCGGTTGTAACGTTAGGAATCATCGCATATGTTTCAGGCACCCCCATTACGGCAAACTACTTGAACATT
CCGTATCTTCCCGGTGCGCACGAATATTCCGTGTTTCTTTCCGCTCTTGCAGGAGCGCTTTTCGGTTTTCTTTGGTTCAA
TGCACATCCGGCCCAGGTGTTTATGGGTGATACAGGCTCCTTATTTTTAGGCGCAACACTCGGGATGATCGTGATCCTTT
TGAAAAAGGAAATTCTTCTTTTGATTTTGGGAGCGATTTTCGTCAGCGAGGCCCTTTCCGTGATCCTTCAAGTCGGTTCG
TTTAAACTGACCGGAAAAAGAATTTTTAAGATGGCGCCCCTACATCATCACTTCGAGTTAGGGGGGGTCAAGGAAACCAA
AATCGTGATCCGTTTCTGGATCATAGCTGTTATTCTCGCCATCATCTCGCTTTCGACTTTGAAAATTCAATGA

Upstream 100 bases:

>100_bases
CAGCGATGTGGAAGAAGTCCGAAAAGCTTTCGGCCTTTTTTAGAAATTTTCCGATACAAAAAAAGAATACTTCGTTTTCT
TGAAAGCAGGACGGACAAAA

Downstream 100 bases:

>100_bases
TCGGATTTATCGCAAAAAAATGGAGAGAAATCTGGCTTCCGGGAAAAAATTCTCTGGATGTTCTTCTGATCGTAACGATT
TTTATTCTTCTTTTTTTCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMFVTFWLGHKVIDFLYGLKFRESVRDDGPKSHESKKGTPTMGGLLII
GSLLLSVLLWGNLKNSNIIVLSVFALCFSALGFADDYMKSVKKIKGGMKARTKFLLSILISLVFCILFFYYTGVIPTGHS
GKIPFQITDLFFPFVKGPVLALGVFAIPFSILVIIGSSHAVNLTDGLDGLATGTVAISVVTLGIIAYVSGTPITANYLNI
PYLPGAHEYSVFLSALAGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGS
FKLTGKRIFKMAPLHHHFELGGVKETKIVIRFWIIAVILAIISLSTLKIQ

Sequences:

>Translated_370_residues
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMFVTFWLGHKVIDFLYGLKFRESVRDDGPKSHESKKGTPTMGGLLII
GSLLLSVLLWGNLKNSNIIVLSVFALCFSALGFADDYMKSVKKIKGGMKARTKFLLSILISLVFCILFFYYTGVIPTGHS
GKIPFQITDLFFPFVKGPVLALGVFAIPFSILVIIGSSHAVNLTDGLDGLATGTVAISVVTLGIIAYVSGTPITANYLNI
PYLPGAHEYSVFLSALAGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGS
FKLTGKRIFKMAPLHHHFELGGVKETKIVIRFWIIAVILAIISLSTLKIQ
>Mature_370_residues
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMFVTFWLGHKVIDFLYGLKFRESVRDDGPKSHESKKGTPTMGGLLII
GSLLLSVLLWGNLKNSNIIVLSVFALCFSALGFADDYMKSVKKIKGGMKARTKFLLSILISLVFCILFFYYTGVIPTGHS
GKIPFQITDLFFPFVKGPVLALGVFAIPFSILVIIGSSHAVNLTDGLDGLATGTVAISVVTLGIIAYVSGTPITANYLNI
PYLPGAHEYSVFLSALAGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGS
FKLTGKRIFKMAPLHHHFELGGVKETKIVIRFWIIAVILAIISLSTLKIQ

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=370, Percent_Identity=44.3243243243243, Blast_Score=312, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_LEPBJ (Q04V92)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_799936.1
- STRING:   Q04V92
- GeneID:   4409378
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_0478
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q04V92
- ProtClustDB:   PRK00108
- BioCyc:   LBOR355277:LBJ_0478-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40560; Mature: 40560

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x121f4d74)-; HASH(0x1276def0)-; HASH(0xfe7eee4)-; HASH(0xfe7ec74)-; HASH(0xfe7ee0c)-; HASH(0xfe7eefc)-; HASH(0xf96eeb0)-; HASH(0x10d60ffc)-; HASH(0xf96ee50)-; HASH(0x1279bdb8)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMFVTFWLGHKVIDFLYGLKFRESVRDD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
GPKSHESKKGTPTMGGLLIIGSLLLSVLLWGNLKNSNIIVLSVFALCFSALGFADDYMKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
VKKIKGGMKARTKFLLSILISLVFCILFFYYTGVIPTGHSGKIPFQITDLFFPFVKGPVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHCCHHH
ALGVFAIPFSILVIIGSSHAVNLTDGLDGLATGTVAISVVTLGIIAYVSGTPITANYLNI
HHHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEC
PYLPGAHEYSVFLSALAGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LILGAIFVSEALSVILQVGSFKLTGKRIFKMAPLHHHFELGGVKETKIVIRFWIIAVILA
HHHHHHHHHHHHHHHHHHCCEEECHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
IISLSTLKIQ
HHHHHHHCCH
>Mature Secondary Structure
MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMFVTFWLGHKVIDFLYGLKFRESVRDD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
GPKSHESKKGTPTMGGLLIIGSLLLSVLLWGNLKNSNIIVLSVFALCFSALGFADDYMKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
VKKIKGGMKARTKFLLSILISLVFCILFFYYTGVIPTGHSGKIPFQITDLFFPFVKGPVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHCCHHH
ALGVFAIPFSILVIIGSSHAVNLTDGLDGLATGTVAISVVTLGIIAYVSGTPITANYLNI
HHHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEC
PYLPGAHEYSVFLSALAGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
LILGAIFVSEALSVILQVGSFKLTGKRIFKMAPLHHHFELGGVKETKIVIRFWIIAVILA
HHHHHHHHHHHHHHHHHHCCEEECHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
IISLSTLKIQ
HHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA