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The map label for this gene is sglT [H]

Identifier: 116329117

GI number: 116329117

Start: 3006444

End: 3008258

Strand: Reverse

Name: sglT [H]

Synonym: LBL_2540

Alternate gene names: 116329117

Gene position: 3008258-3006444 (Counterclockwise)

Preceding gene: 116329119

Following gene: 116329116

Centisome position: 83.23

GC content: 45.56

Gene sequence:

>1815_bases
ATGTTCAGTGTTCTCGATTGGTTTTTCATCTTGTTGTATTTATTATTTGCGTTTGCTGCGGGAATTTTGCTTTCTCCCAA
AGCGGGCAAAAGTCTCGTTTCTTACTTTGTCGCCGATCGTAAACTTCCTTGGTGGTGGCTCGGAACTTCGATGGTCGCGA
CTACGTTTGCGGCGGATACTCCTCTTGTGATCACCGGTTTTGTGGCTGCGGACGGAATTTCGGCTAACTGGTTTTGGTGG
AGTTGGGCGATCGGTTATATGGCGATGACAGTTTTTTTTGCGGGAAAATGGAGAAAGATGGAAGTCCTTACCGATGTCGA
GTTTGTCGAACTGCGGTACGGTGGAAAACCGGCGACTATTCTCCGTATGGTCAAAGCGTTCTATTTAAGTATATTAGTAA
ATTCGATTGTACTGGGGTGGGTATTCAAAGCGATGTCCAAAATCACTGGTCCTTTTTTGGATTGGACGGATATACTCGGC
GTGGACGGATTTGCGATCGTTCGGAATCTTTGGCCTTCTTTTCTAATATTCGATTCTTTAAATAATACGATCACGGTGTT
GATTCTGTTTTTGATCGTGGTCGTCTATAGCAGTATGGGAGGAATCCAAGGTGTGATTCTGACTGATCTCGTTCAGTTTG
CTTTAGGAATGGGAGGAGCGATCCTTTTTGCGGTGTACGCCGTTTCTAGCCAAGGGGGGATTTCCGGTCTACTTATGGGA
ATGAAAGAAATCTATCCGGACAAACACGAATCCATCTTGAGTTTTTGGCCGGATTTTCAAGGCGCCTCCCTTCCGTTTAA
CGTTTTCCTGATATTTATATCCGTACAATGGTGGGCTCAGTATTATTCGGACGGTTCGGGATATTTGGCGCAGCGAATTC
ACACCGCAAAAAGTCCGGAGGAAGCGGAGAAGGGTTCTCTTTGGTTCAACGTGGCGAACTTTATTGTTCGAACCTGGCCT
TGGATCTTGACCGCGCTCGTAACGTTAGTCGTATTTCCTCTGCACGATCCGACGCGATATTTTTCGGAAGGACAAATCGT
GGGTGGCGACCGCGAGATGGGTTATCCGATTTTAATGAAACTTATATTGCCGAGCGGAGTTTTGGGAATCGTATTTGCGA
GTTTGATGGCGGCGTTTATGTCCACGGCGGACACTCATATCAATTGGGGCGCGAGTTATTTGGTGAACGATTTTTATCTG
AGATTCCTTCATCCGGGTGCGGATGATAAGACTTTGGTAAGAGTGAGTCGAATCGCTGTTGTTCTGATGGCAATCGTAGC
CGTTCTCGTGGCGACCCAGATTCAATCCATCGCGAGTGCCTGGAAATTTTTATTGGCGTTTGCTTCGGGTATGGGATTGC
CTCAGATTTTACGATGGATTTGGTGGAGGACCAACGCTTGGACGGAACTTTCCGGTATGATCACGGCTTTGACGCTATCG
ATGATTTTATATCCTTTTTTTCCCGAGGTTCGATCGGAATACCTTTTATTTTGGGTGGCGATCGGTTCCGTCGCGGTTTC
GATCCTCGTTACCTTAACGACTCCCCCTGTTTCGAAATATACGTTAGACGCATTTGTAAAAAGGGCCGACCCTTTCGGAT
TTTGGAAAGGACAAGGTAGTAAAGAAAGGCTCGAGGATTTTCAGGAAAAAATCGTAATTTGGATTTTGGGAACCGTTTCG
TTGTTTTTCGGAATGTTTTCTTTGGGATGTTTTTTTCTTTTGAAGTTTTGGCAAGGCGCATGTTGTCTGATTGGCTTTGT
CGCTTTCGGTTTCTTCTATTGGAAAAAAGAATTCGGTAATAACGGGATCGACTAA

Upstream 100 bases:

>100_bases
GGTTTTGTTCTCAGGAAAGGTTTTAAAACTGACGAAAGTTTTATCAATACCGTAGAATTTCGTTTTCGAACGAATTTCCA
TTCCACCTTAAGAAGAAAAT

Downstream 100 bases:

>100_bases
AAAACTTTCCTGTTTTTGAATATTCAAGAAAATTTAATCTCTATTTGCGCTGAGCGCTCGGTTCTAGTTTATAACGTCAA
TGGTAATGATTGAATGAATA

Product: Sodium/proline symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MFSVLDWFFILLYLLFAFAAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFVAADGISANWFWW
SWAIGYMAMTVFFAGKWRKMEVLTDVEFVELRYGGKPATILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWTDILG
VDGFAIVRNLWPSFLIFDSLNNTITVLILFLIVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLMG
MKEIYPDKHESILSFWPDFQGASLPFNVFLIFISVQWWAQYYSDGSGYLAQRIHTAKSPEEAEKGSLWFNVANFIVRTWP
WILTALVTLVVFPLHDPTRYFSEGQIVGGDREMGYPILMKLILPSGVLGIVFASLMAAFMSTADTHINWGASYLVNDFYL
RFLHPGADDKTLVRVSRIAVVLMAIVAVLVATQIQSIASAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALTLS
MILYPFFPEVRSEYLLFWVAIGSVAVSILVTLTTPPVSKYTLDAFVKRADPFGFWKGQGSKERLEDFQEKIVIWILGTVS
LFFGMFSLGCFFLLKFWQGACCLIGFVAFGFFYWKKEFGNNGID

Sequences:

>Translated_604_residues
MFSVLDWFFILLYLLFAFAAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFVAADGISANWFWW
SWAIGYMAMTVFFAGKWRKMEVLTDVEFVELRYGGKPATILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWTDILG
VDGFAIVRNLWPSFLIFDSLNNTITVLILFLIVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLMG
MKEIYPDKHESILSFWPDFQGASLPFNVFLIFISVQWWAQYYSDGSGYLAQRIHTAKSPEEAEKGSLWFNVANFIVRTWP
WILTALVTLVVFPLHDPTRYFSEGQIVGGDREMGYPILMKLILPSGVLGIVFASLMAAFMSTADTHINWGASYLVNDFYL
RFLHPGADDKTLVRVSRIAVVLMAIVAVLVATQIQSIASAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALTLS
MILYPFFPEVRSEYLLFWVAIGSVAVSILVTLTTPPVSKYTLDAFVKRADPFGFWKGQGSKERLEDFQEKIVIWILGTVS
LFFGMFSLGCFFLLKFWQGACCLIGFVAFGFFYWKKEFGNNGID
>Mature_604_residues
MFSVLDWFFILLYLLFAFAAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADTPLVITGFVAADGISANWFWW
SWAIGYMAMTVFFAGKWRKMEVLTDVEFVELRYGGKPATILRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWTDILG
VDGFAIVRNLWPSFLIFDSLNNTITVLILFLIVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLMG
MKEIYPDKHESILSFWPDFQGASLPFNVFLIFISVQWWAQYYSDGSGYLAQRIHTAKSPEEAEKGSLWFNVANFIVRTWP
WILTALVTLVVFPLHDPTRYFSEGQIVGGDREMGYPILMKLILPSGVLGIVFASLMAAFMSTADTHINWGASYLVNDFYL
RFLHPGADDKTLVRVSRIAVVLMAIVAVLVATQIQSIASAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALTLS
MILYPFFPEVRSEYLLFWVAIGSVAVSILVTLTTPPVSKYTLDAFVKRADPFGFWKGQGSKERLEDFQEKIVIWILGTVS
LFFGMFSLGCFFLLKFWQGACCLIGFVAFGFFYWKKEFGNNGID

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI109659836, Length=626, Percent_Identity=21.2460063897764, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI17941285, Length=494, Percent_Identity=25.3036437246964, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI109659839, Length=641, Percent_Identity=20.7488299531981, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI14140236, Length=614, Percent_Identity=18.7296416938111, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4507033, Length=440, Percent_Identity=22.9545454545455, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI206597483, Length=448, Percent_Identity=23.4375, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4507031, Length=487, Percent_Identity=20.1232032854209, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 67824; Mature: 67824

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVLDWFFILLYLLFAFAAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADT
CCHHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCC
PLVITGFVAADGISANWFWWSWAIGYMAMTVFFAGKWRKMEVLTDVEFVELRYGGKPATI
CEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCEEEEEEECCCHHHH
LRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWTDILGVDGFAIVRNLWPSFLIFDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCHHHHHHHCC
NNTITVLILFLIVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLMG
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHH
MKEIYPDKHESILSFWPDFQGASLPFNVFLIFISVQWWAQYYSDGSGYLAQRIHTAKSPE
HHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
EAEKGSLWFNVANFIVRTWPWILTALVTLVVFPLHDPTRYFSEGQIVGGDREMGYPILMK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCCCHHHHHH
LILPSGVLGIVFASLMAAFMSTADTHINWGASYLVNDFYLRFLHPGADDKTLVRVSRIAV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VLMAIVAVLVATQIQSIASAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MILYPFFPEVRSEYLLFWVAIGSVAVSILVTLTTPPVSKYTLDAFVKRADPFGFWKGQGS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCCC
KERLEDFQEKIVIWILGTVSLFFGMFSLGCFFLLKFWQGACCLIGFVAFGFFYWKKEFGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
NGID
CCCC
>Mature Secondary Structure
MFSVLDWFFILLYLLFAFAAGILLSPKAGKSLVSYFVADRKLPWWWLGTSMVATTFAADT
CCHHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHCCCC
PLVITGFVAADGISANWFWWSWAIGYMAMTVFFAGKWRKMEVLTDVEFVELRYGGKPATI
CEEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCEEEEEEECCCHHHH
LRMVKAFYLSILVNSIVLGWVFKAMSKITGPFLDWTDILGVDGFAIVRNLWPSFLIFDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCHHHHHHHCC
NNTITVLILFLIVVVYSSMGGIQGVILTDLVQFALGMGGAILFAVYAVSSQGGISGLLMG
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHH
MKEIYPDKHESILSFWPDFQGASLPFNVFLIFISVQWWAQYYSDGSGYLAQRIHTAKSPE
HHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
EAEKGSLWFNVANFIVRTWPWILTALVTLVVFPLHDPTRYFSEGQIVGGDREMGYPILMK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEECCCCCCCHHHHHH
LILPSGVLGIVFASLMAAFMSTADTHINWGASYLVNDFYLRFLHPGADDKTLVRVSRIAV
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VLMAIVAVLVATQIQSIASAWKFLLAFASGMGLPQILRWIWWRTNAWTELSGMITALTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MILYPFFPEVRSEYLLFWVAIGSVAVSILVTLTTPPVSKYTLDAFVKRADPFGFWKGQGS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCCC
KERLEDFQEKIVIWILGTVSLFFGMFSLGCFFLLKFWQGACCLIGFVAFGFFYWKKEFGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
NGID
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]