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The map label for this gene is ksgA [H]

Identifier: 116328998

GI number: 116328998

Start: 2849168

End: 2850073

Strand: Direct

Name: ksgA [H]

Synonym: LBL_2401

Alternate gene names: 116328998

Gene position: 2849168-2850073 (Clockwise)

Preceding gene: 116328997

Following gene: 116329002

Centisome position: 78.83

GC content: 41.72

Gene sequence:

>906_bases
ATGAGCTCCAGAGAATACCCATTTCGAAAAGTTTCTGAAATCCGCAAATTTCTGGAGTCGAAATCCTCGGCCCCATTAAA
AAAATGGGGACAGAACTTTTTAATCGATCCGAATGCAATCCGATCCATTCTCAACTGCCTAAGTTCCGACCTTCTTTCGA
CAATTGATCGAATTTTGGAAATCGGTCCGGGGCTCGGCGCAATTTCACATGGATTACTCGACTTCCAAAAACCGGTCACG
TTATTCGAAATCGATCCGGTTTACGCACATTGGCTCCGGGAATATCTTCCGGAATTCGAAATCAGGGAAGGTAACGCTTT
AGACTTTTTGCACGAATACTCCCAAAATTCTACTTATCTCTTTGGAAACCTCCCCTACTATATTTCTTCGGAACTGACTT
TAAGCTCCGTTAAAAATTTAAAAGAACTCAAAGGCGCGGCGTTTCTTGTACAAAAAGAATTTGCAAAAAGAATTTCAAGC
GAACCTTCTTCGATTCAATTTTATCTTTCTGCGTACGGAAATTGGAGTTTAAAAAAAGACGTCAAGGCCGGGGCTTTTTA
TCCGAGGCCGAACGTGGATTCCTCCATACTAGAATATAAATCTTGTCCGGTATTCGAGAAACAATCCGGATTTATCGCAC
TCGAATGCCTTTGCAGAACCGCCTTCTGGGGAAAAAGAAAAAAACTAACTTCCTCTCTTCGAAACGCACCAATCGCCTCC
CTGCCCGTTGAAGTTGTTTCCTCCGAAAATTTTTCAGAAGAACAGTTTAGAAATGAAAGCGTCCAATCCTTGGAAAACGC
AGGAATCGATCTCAATAAAAGACCGGAAGAATTGAGGACGGCGGATTTCCACGAAGCAGCACAATCACTTTCCACTTATA
TATCAAAAATACTGAATATAATGTGA

Upstream 100 bases:

>100_bases
CTTTTAGAAACTCCGTACGGAAGCCGGGATGATTCGGAAGTCTGGAATCGAAACCGAAAACTGCTTGGGCTTTCGGAGAA
TTGGATGTTTCTGGAAAAAG

Downstream 100 bases:

>100_bases
GTTTGGCGTAAGAAAATGAGAAAGAATTTTCTAAAAGTAAGAGTCCCCACTTTTAGAATTTGTTTGTAAAATCGCGATCT
GTTGCAGTTCCACGTTTTAA

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILNCLSSDLLSTIDRILEIGPGLGAISHGLLDFQKPVT
LFEIDPVYAHWLREYLPEFEIREGNALDFLHEYSQNSTYLFGNLPYYISSELTLSSVKNLKELKGAAFLVQKEFAKRISS
EPSSIQFYLSAYGNWSLKKDVKAGAFYPRPNVDSSILEYKSCPVFEKQSGFIALECLCRTAFWGKRKKLTSSLRNAPIAS
LPVEVVSSENFSEEQFRNESVQSLENAGIDLNKRPEELRTADFHEAAQSLSTYISKILNIM

Sequences:

>Translated_301_residues
MSSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILNCLSSDLLSTIDRILEIGPGLGAISHGLLDFQKPVT
LFEIDPVYAHWLREYLPEFEIREGNALDFLHEYSQNSTYLFGNLPYYISSELTLSSVKNLKELKGAAFLVQKEFAKRISS
EPSSIQFYLSAYGNWSLKKDVKAGAFYPRPNVDSSILEYKSCPVFEKQSGFIALECLCRTAFWGKRKKLTSSLRNAPIAS
LPVEVVSSENFSEEQFRNESVQSLENAGIDLNKRPEELRTADFHEAAQSLSTYISKILNIM
>Mature_300_residues
SSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILNCLSSDLLSTIDRILEIGPGLGAISHGLLDFQKPVTL
FEIDPVYAHWLREYLPEFEIREGNALDFLHEYSQNSTYLFGNLPYYISSELTLSSVKNLKELKGAAFLVQKEFAKRISSE
PSSIQFYLSAYGNWSLKKDVKAGAFYPRPNVDSSILEYKSCPVFEKQSGFIALECLCRTAFWGKRKKLTSSLRNAPIASL
PVEVVSSENFSEEQFRNESVQSLENAGIDLNKRPEELRTADFHEAAQSLSTYISKILNIM

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786236, Length=285, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI25146882, Length=286, Percent_Identity=26.2237762237762, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358017, Length=223, Percent_Identity=30.0448430493274, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 34194; Mature: 34063

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS01131 RRNA_A_DIMETH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILNCLSSDLLSTIDRILE
CCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGPGLGAISHGLLDFQKPVTLFEIDPVYAHWLREYLPEFEIREGNALDFLHEYSQNSTYL
CCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCEEE
FGNLPYYISSELTLSSVKNLKELKGAAFLVQKEFAKRISSEPSSIQFYLSAYGNWSLKKD
EECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
VKAGAFYPRPNVDSSILEYKSCPVFEKQSGFIALECLCRTAFWGKRKKLTSSLRNAPIAS
CCCCCCCCCCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPVEVVSSENFSEEQFRNESVQSLENAGIDLNKRPEELRTADFHEAAQSLSTYISKILNI
CCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
M
C
>Mature Secondary Structure 
SSREYPFRKVSEIRKFLESKSSAPLKKWGQNFLIDPNAIRSILNCLSSDLLSTIDRILE
CCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGPGLGAISHGLLDFQKPVTLFEIDPVYAHWLREYLPEFEIREGNALDFLHEYSQNSTYL
CCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCEEE
FGNLPYYISSELTLSSVKNLKELKGAAFLVQKEFAKRISSEPSSIQFYLSAYGNWSLKKD
EECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHH
VKAGAFYPRPNVDSSILEYKSCPVFEKQSGFIALECLCRTAFWGKRKKLTSSLRNAPIAS
CCCCCCCCCCCCCHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPVEVVSSENFSEEQFRNESVQSLENAGIDLNKRPEELRTADFHEAAQSLSTYISKILNI
CCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
M
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA