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The map label for this gene is recD [H]

Identifier: 116328994

GI number: 116328994

Start: 2842121

End: 2843971

Strand: Direct

Name: recD [H]

Synonym: LBL_2396

Alternate gene names: 116328994

Gene position: 2842121-2843971 (Clockwise)

Preceding gene: 116328993

Following gene: 116328995

Centisome position: 78.63

GC content: 42.25

Gene sequence:

>1851_bases
TTGATGGAAGAGTCGTTCTCCCATTTTATTGAAAAACTCAAAGCGGACATTTTAGACTTGTACGAATCCGGGGCCCTGAA
AAAAATTCCCGAAAATTTTTCGGATTATTTATTAGAAATTCTGAATTCGATTTGGAGTTCCATGGAAGAGGGAAGTTTAT
GCGTCCCCGTAAAAAAGGAATGGAGGGACGTTTTAAAATTAAAACCTCCCGGTTTAGTCGTGGACAAATTCGAAAACCAG
GAATGGGTTTACTTCGAAAAAACGCATCGATCCAAAACCGATCTGGAAAGTCTCCTAAAGGAAAGGATTCAAAACGACGT
TCCGCCGAAAGTCGACCGACACCGTGCCGAGAAAATTCTCAAAAATCTGGAATCAAAAAGTTTTCCATTAAAAGAAGCGC
AGGTAAAGACGATTCTTTCCTGTCTCAATTCCTCCTTTCACATCGTCAGCGGAGGCCCGGGAACCGGAAAAACGACGGTC
GTCGCATTTCTATTAGAAATTTTGAATCAACTGGGACAACTTCCTTCTCCCGAAGAAATCGCGCTCGTGGCGCCTACGGG
AAGAGCTGCACAAAGATTAACGGAATCGATTCAGGAAAACCTAAAAAAAATCTCCGAAATGAAAGGATCCGATTTCTTAC
GGGGACAAACTGTTCACGGACTTCTCTCCTACAAATCGTCGTTAGGCGGATTTTATTACAACCGGGAAAGATACCTTCCG
CATCGATTGATCATCGTGGACGAAGTTTCGATGGTCGATTTAAATCTGATGCTTTCCTTATGGAACGCAATCCCTCGCGA
TACCAAAAAAGACGACCGAAAAATTCCGCTCCGATTCATACTGATCGGAGATCCGCATCAACTTCCTTCCGTGGAAAAGG
GCGCGGTATTAAGCGACTTTTTATCCGTACTAGAATCGAAAAAAGCGAATTTTGCCTCCAGACTCGAGGGAAGCAATCGT
CAAAAATCGAAGGGGAACGTTTCAAAAATCGTCGTTCTTGCGGAAGAAATCCTCGGATATTCCCCCGAAAACCTAAATCT
CGGAACAAAGATAGACGATTCTTTTCCGAAAACGACGACGATCGGAGAGAATTCGAAATATGAAAGCGAAGTTGTATGGT
TGCAAAATCCCGCAAATAAAACTTCGGATCACTTATCGAGAGACGAAGTCGTTGAAAAACTTTGGACCGAAATTTTTCAT
CCCGGGATTTCCAAAATTGGGACTTGGAAAGTCAAGGATTCTTTCGACTTAAACGAGGCCGGCTTTATTTTAAAATTTCA
GGAGGAGTTGAAAAAATTCCGCTGTCTTACCGTTTTTAGAAACGGTTATTGGGGAGTGGAAGCGATTCAAACGAAAATTA
TGAATCTGGCCGCGCAGGATCTTTTTCATAGAAAAGACCAAAAACCGGATTTTTTCGCAAAACGCCTTTCCAAACGTCTT
TACTTTATAGGGCTTCCCATCTTAATCACGCAAAACGATAAAAACAGAAAACTTTTCAACGGCGATATCGGTATCGTTTT
AAGAATGGAATCGACCGGAGAACTCAGAGCGGTTTTTCCGATCGAAGGTAAATTATTGCCTTTCGCGTTAGACACTCTTC
CGAAACACGAACCCGCATTCGTGATGAGCATTCACAAAAGTCAGGGATCAGAATATGATACAATTCTAATCTATATTCCG
GATCATCCGGAATCTCAGGAAAAGGAACGATCTCATAGACTTCTCAACCGTCAGATTTTATACACTGGAATCACAAGAGC
CAAAAACCAAGTAATTCTTGCGGGCAACCCGAAGACCTGGGAAATCGGAATCGCCAATTCTCAGAAGAGAAACACCGGTT
TTAAAATTTAA

Upstream 100 bases:

>100_bases
ACTCCGGAATTTATTCGGACTTTCATTGGAGTCCGGACAGAATGGAAACGATCCACAAAATCGTACGGGAACTGACTGCC
GTTCACTGGTTGGAGGATCT

Downstream 100 bases:

>100_bases
ATCGGTTTGGGCATTCTCAGGATTTCACAAATCGCCCTCTCGAAAGAAGGATTCGATAAAAAACTGAATTACAAATCTAG
TTTAAAAAATCGAAATGATG

Product: exodeoxyribonuclease V, alpha subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MMEESFSHFIEKLKADILDLYESGALKKIPENFSDYLLEILNSIWSSMEEGSLCVPVKKEWRDVLKLKPPGLVVDKFENQ
EWVYFEKTHRSKTDLESLLKERIQNDVPPKVDRHRAEKILKNLESKSFPLKEAQVKTILSCLNSSFHIVSGGPGTGKTTV
VAFLLEILNQLGQLPSPEEIALVAPTGRAAQRLTESIQENLKKISEMKGSDFLRGQTVHGLLSYKSSLGGFYYNRERYLP
HRLIIVDEVSMVDLNLMLSLWNAIPRDTKKDDRKIPLRFILIGDPHQLPSVEKGAVLSDFLSVLESKKANFASRLEGSNR
QKSKGNVSKIVVLAEEILGYSPENLNLGTKIDDSFPKTTTIGENSKYESEVVWLQNPANKTSDHLSRDEVVEKLWTEIFH
PGISKIGTWKVKDSFDLNEAGFILKFQEELKKFRCLTVFRNGYWGVEAIQTKIMNLAAQDLFHRKDQKPDFFAKRLSKRL
YFIGLPILITQNDKNRKLFNGDIGIVLRMESTGELRAVFPIEGKLLPFALDTLPKHEPAFVMSIHKSQGSEYDTILIYIP
DHPESQEKERSHRLLNRQILYTGITRAKNQVILAGNPKTWEIGIANSQKRNTGFKI

Sequences:

>Translated_616_residues
MMEESFSHFIEKLKADILDLYESGALKKIPENFSDYLLEILNSIWSSMEEGSLCVPVKKEWRDVLKLKPPGLVVDKFENQ
EWVYFEKTHRSKTDLESLLKERIQNDVPPKVDRHRAEKILKNLESKSFPLKEAQVKTILSCLNSSFHIVSGGPGTGKTTV
VAFLLEILNQLGQLPSPEEIALVAPTGRAAQRLTESIQENLKKISEMKGSDFLRGQTVHGLLSYKSSLGGFYYNRERYLP
HRLIIVDEVSMVDLNLMLSLWNAIPRDTKKDDRKIPLRFILIGDPHQLPSVEKGAVLSDFLSVLESKKANFASRLEGSNR
QKSKGNVSKIVVLAEEILGYSPENLNLGTKIDDSFPKTTTIGENSKYESEVVWLQNPANKTSDHLSRDEVVEKLWTEIFH
PGISKIGTWKVKDSFDLNEAGFILKFQEELKKFRCLTVFRNGYWGVEAIQTKIMNLAAQDLFHRKDQKPDFFAKRLSKRL
YFIGLPILITQNDKNRKLFNGDIGIVLRMESTGELRAVFPIEGKLLPFALDTLPKHEPAFVMSIHKSQGSEYDTILIYIP
DHPESQEKERSHRLLNRQILYTGITRAKNQVILAGNPKTWEIGIANSQKRNTGFKI
>Mature_616_residues
MMEESFSHFIEKLKADILDLYESGALKKIPENFSDYLLEILNSIWSSMEEGSLCVPVKKEWRDVLKLKPPGLVVDKFENQ
EWVYFEKTHRSKTDLESLLKERIQNDVPPKVDRHRAEKILKNLESKSFPLKEAQVKTILSCLNSSFHIVSGGPGTGKTTV
VAFLLEILNQLGQLPSPEEIALVAPTGRAAQRLTESIQENLKKISEMKGSDFLRGQTVHGLLSYKSSLGGFYYNRERYLP
HRLIIVDEVSMVDLNLMLSLWNAIPRDTKKDDRKIPLRFILIGDPHQLPSVEKGAVLSDFLSVLESKKANFASRLEGSNR
QKSKGNVSKIVVLAEEILGYSPENLNLGTKIDDSFPKTTTIGENSKYESEVVWLQNPANKTSDHLSRDEVVEKLWTEIFH
PGISKIGTWKVKDSFDLNEAGFILKFQEELKKFRCLTVFRNGYWGVEAIQTKIMNLAAQDLFHRKDQKPDFFAKRLSKRL
YFIGLPILITQNDKNRKLFNGDIGIVLRMESTGELRAVFPIEGKLLPFALDTLPKHEPAFVMSIHKSQGSEYDTILIYIP
DHPESQEKERSHRLLNRQILYTGITRAKNQVILAGNPKTWEIGIANSQKRNTGFKI

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=511, Percent_Identity=28.3757338551859, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 70238; Mature: 70238

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEESFSHFIEKLKADILDLYESGALKKIPENFSDYLLEILNSIWSSMEEGSLCVPVKKE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCHHH
WRDVLKLKPPGLVVDKFENQEWVYFEKTHRSKTDLESLLKERIQNDVPPKVDRHRAEKIL
HHHHHHCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
KNLESKSFPLKEAQVKTILSCLNSSFHIVSGGPGTGKTTVVAFLLEILNQLGQLPSPEEI
HHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCE
ALVAPTGRAAQRLTESIQENLKKISEMKGSDFLRGQTVHGLLSYKSSLGGFYYNRERYLP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCC
HRLIIVDEVSMVDLNLMLSLWNAIPRDTKKDDRKIPLRFILIGDPHQLPSVEKGAVLSDF
EEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
LSVLESKKANFASRLEGSNRQKSKGNVSKIVVLAEEILGYSPENLNLGTKIDDSFPKTTT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEHHHHHCCCCCCCCCCCCCCCCCCCCCC
IGENSKYESEVVWLQNPANKTSDHLSRDEVVEKLWTEIFHPGISKIGTWKVKDSFDLNEA
CCCCCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCCHHHCCEEEECCCCCCCCC
GFILKFQEELKKFRCLTVFRNGYWGVEAIQTKIMNLAAQDLFHRKDQKPDFFAKRLSKRL
CEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCE
YFIGLPILITQNDKNRKLFNGDIGIVLRMESTGELRAVFPIEGKLLPFALDTLPKHEPAF
EEEECEEEEECCCCCCEEECCCEEEEEEEECCCCEEEEEECCCCCCHHHHHCCCCCCCEE
VMSIHKSQGSEYDTILIYIPDHPESQEKERSHRLLNRQILYTGITRAKNQVILAGNPKTW
EEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
EIGIANSQKRNTGFKI
EEECCCCCCCCCCCCC
>Mature Secondary Structure
MMEESFSHFIEKLKADILDLYESGALKKIPENFSDYLLEILNSIWSSMEEGSLCVPVKKE
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEECCHHH
WRDVLKLKPPGLVVDKFENQEWVYFEKTHRSKTDLESLLKERIQNDVPPKVDRHRAEKIL
HHHHHHCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
KNLESKSFPLKEAQVKTILSCLNSSFHIVSGGPGTGKTTVVAFLLEILNQLGQLPSPEEI
HHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCE
ALVAPTGRAAQRLTESIQENLKKISEMKGSDFLRGQTVHGLLSYKSSLGGFYYNRERYLP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCCC
HRLIIVDEVSMVDLNLMLSLWNAIPRDTKKDDRKIPLRFILIGDPHQLPSVEKGAVLSDF
EEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
LSVLESKKANFASRLEGSNRQKSKGNVSKIVVLAEEILGYSPENLNLGTKIDDSFPKTTT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEHHHHHCCCCCCCCCCCCCCCCCCCCCC
IGENSKYESEVVWLQNPANKTSDHLSRDEVVEKLWTEIFHPGISKIGTWKVKDSFDLNEA
CCCCCCCCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHCCCHHHCCEEEECCCCCCCCC
GFILKFQEELKKFRCLTVFRNGYWGVEAIQTKIMNLAAQDLFHRKDQKPDFFAKRLSKRL
CEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCE
YFIGLPILITQNDKNRKLFNGDIGIVLRMESTGELRAVFPIEGKLLPFALDTLPKHEPAF
EEEECEEEEECCCCCCEEECCCEEEEEEEECCCCEEEEEECCCCCCHHHHHCCCCCCCEE
VMSIHKSQGSEYDTILIYIPDHPESQEKERSHRLLNRQILYTGITRAKNQVILAGNPKTW
EEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEE
EIGIANSQKRNTGFKI
EEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]