| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is greA [H]
Identifier: 116328972
GI number: 116328972
Start: 2815299
End: 2818082
Strand: Reverse
Name: greA [H]
Synonym: LBL_2374
Alternate gene names: 116328972
Gene position: 2818082-2815299 (Counterclockwise)
Preceding gene: 116328973
Following gene: 116328971
Centisome position: 77.97
GC content: 41.27
Gene sequence:
>2784_bases ATGTCTAACGAAATATCAGCAACTACGGAATCCAGACCGGCCAGCGATTTGGATAAGCTGACATCTCTTTTCAATGAAGA AATTTATGTTCGCACGGATGCAAGTTCTATTCCTGCATCCAAGTTTAAAATTTTTGACGATCTCATCGAATTTTATAAAT CAGCCGGAAAAATAGACGAAGCAAAGCGGAAAATCGAGGAATATCTTTCCGAACATGAAGACAGTATCTCCGCGAGATAT TTGCTTGGAATTCTTTCTTTGGAAAGGGGAGAAATCAGCGACTCCGGTCTTTTGAAAAATTTATTAGAATCTTTTAAAGT AGCTGGTAAGTGGGCAATTATAGAACATATCACTGATCAAATCCTGAAATACGGAGATCAAAGACTTGCTCTCAAATACA AAGCCGAGGCGCTAGAAAAGTTAAAGAAAAATAAAGAACTCAAAGTCGTATTGGAAAAACTCGCAAAACACGACCGCAAA AATCCTGAGATTTTAAAAAAATACGCGCTTTCTATCTTAGAGGAAAATAAAGAAAGAGCGATCACCTATCTCAAGCAGGC GATTGAAACTTTCGCAAAGACAAAAGATTATGTTCAACTGGAAGAGATCTGGTCGATCATCGTAAGCAATAATCACGAAG ACCTTCAATTTTTCGAAAGAATTGAAAGAATTATGTTGGGTCATAGGGAAAGAACCAGGCTTGTCGGTTATCTTTATCCG ATCGTAGAACCTTACAAACAGTTGGAAGACTGGGATAAGGTGATCTATCTTTTAAAGAAAATTCTAGAACACGAAGCTTC TTCCAACAAGGCAAGAAACGAACTCATCCGCGCTTATAAGGCAAAGTATGCGAATCATTCCCTTCTGGAAGATTTTCTCA AAATGTCCGAGATCGGAAATAACAGAAAGCCGATCAAAGTGTGTATCGCCAATTTTGAAAGAAATATCGTATTCGACACG AATAACTATGTTCTCCATAGAAACTGGGGAGTCGGGAAAATCACTTCCATTTCGCCTAACGGAGATTCCATTTTTGTGGA CTTCAAGGATAAGAAGGATCATAAACTTTCGATCCAGATGGCGATCACAAGTTTAAAACCTCTGAAAAAAGATCATATAT GGGTGAAATATTATGAAAATAAAGAGGAGATTGTGGATCTCTTTCAGAATAATATTCCCGATTTTTTCAAGGAACTTCTG ACTTCTTTCAACAATAGAATGTTGACCGCGGACATCAAATCCGAGGTTGCCGGAAAGTTTCTTCCCGCTCTGGAGTGGTC CAAGTGGTGGAATAAGGCCAAAAACATAATCAAAAAAGAGCCCAATATCGGATTCGATCCTAAGAAAAAGGACGAACTTG TGTATCGTGAAAAAGCGATATCTTTGTCGGAAGAGTTGTCGGAGAAGTTTACTCATCAGACCGACGCGAACAAAAAACTC GATATCGCGATGGAAGCCCTGGACAATCGCGAGGATGCGGAAGGTGCAATCGAAGCTTTCAATCATTTTTATTATGAAGA AGAGGAAGCGGCGGATCCGGTTCGTAAGATTGTAGCGTTTTTATATTTGCAAGCCGCGTCGGAAGAACTTGGAGACGAGG AAATACCAAGACATCTCAGTGAACAAAAAATCGCAGAACTCATTAAATCTCTTCCTGTAAATAATCTCACAGAAATTTCC ACAAAGATCGGAAACGTGGAAATCAAAAAAAGTTATGTGAATTTGATACGCAAACACGCGCATAATCCGGAGGAGGTTTT GGTCGGAATTCTTTTTGAAGTGCCGATTAAGGTGAACAAATACGTATTTTCTATTTTAGAAGAAGAGGGTAAGTTCGACC TTCTCAATTCGTTTATCAAATCCGCAGGTACGAGAGCGAAGGAAGCTCCCGAGGTTTTTATCTGGGTTGCTAAGTCTATT CTTACCAAAACTTGGGAAGGAGAATGGCTTGTGTCTTCCAGGTCGGAGGAACGTCTCGAGTTGATCCTGAGGGTCTTTCG TTTATTTAAACCTCTTGCCAAGATAGAGGATAAAGGAACTAAACTTAAGAACGCTTGTAAGGAAATTCTTCATGGAAATG ACGACGAAGTTCTTCGGGAGGCGATACATTCCGGAGACTCCGAATACATTCGAAAGTTATATGCTCTCTACAAAGAGGTT CCCTATTTCACCGATCTTGAAAAGGAACGTCTGTATTCTTTGATCGTAGAGTTGAAGCCGGATGTCGCTTGGGACGAAGA CGAAGACGAAGATGAAGAAGGCGACGACGACATTCTCAACCGGATTCCGGAGGGTGCGATTTTAGTTACAAGACGAGCTC TCAATCGTAAGAAGGAAGAGTTCGAACATCTTCTCAATGTCGAGATGCCGGAAAACTCCAAGGATATCGGGGAAGCTCAA GAAAGAGGGGATTTGCGGGAAAACGCGGAATACAAGGCCGCGATGGAACGTCAGGTTCAGTTGCAGGCCGCTATCAAAAG ACTCGAAGCGGAAATCAAGAGTGCGATTATTCTGGATCTTACTAACGTCAAAACCGACAAGATCAATATAGGGGTTACAG CAAAACTCAAAAACGAATCCACCGGAGAAGTGGTGGCTTATTCTATTTTGGGCGCTTGGGATGCGGATACGGAAAAACAC ATTATCAGCTATCAATCTCCTCTCGCTAAATCTTTGCTTGGTAAAAAGGTCGGGGACGCTGCGGTTTTGAATCTTACGGG AGCGGAAACTCGTTACACGGTTCTCGAGATCGGAAGGTTTTCTTTGCAAACCCAAGAAGATTAG
Upstream 100 bases:
>100_bases CAACTCATCTATAATTGATAAATACAGGGCTATTCAGAGAGGAATTTAACCCCAAAGTCCCAATTTTCATCAAGCCGAGA TTCAATCGGTGGAGTATCCT
Downstream 100 bases:
>100_bases AACATCTCGGATCAACCTGTCCCAACCAATCCATAAAAAGGTTGTGTTGGGTTCACTGTTGAAATGTCCTATTGGAAGTA AATATTGAAGTACGGCGTAT
Product: transcript cleavage factor/unknown domain fusion protein
Products: NA
Alternate protein names: Transcript cleavage factor greA [H]
Number of amino acids: Translated: 927; Mature: 926
Protein sequence:
>927_residues MSNEISATTESRPASDLDKLTSLFNEEIYVRTDASSIPASKFKIFDDLIEFYKSAGKIDEAKRKIEEYLSEHEDSISARY LLGILSLERGEISDSGLLKNLLESFKVAGKWAIIEHITDQILKYGDQRLALKYKAEALEKLKKNKELKVVLEKLAKHDRK NPEILKKYALSILEENKERAITYLKQAIETFAKTKDYVQLEEIWSIIVSNNHEDLQFFERIERIMLGHRERTRLVGYLYP IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYANHSLLEDFLKMSEIGNNRKPIKVCIANFERNIVFDT NNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQMAITSLKPLKKDHIWVKYYENKEEIVDLFQNNIPDFFKELL TSFNNRMLTADIKSEVAGKFLPALEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFTHQTDANKKL DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQAASEELGDEEIPRHLSEQKIAELIKSLPVNNLTEIS TKIGNVEIKKSYVNLIRKHAHNPEEVLVGILFEVPIKVNKYVFSILEEEGKFDLLNSFIKSAGTRAKEAPEVFIWVAKSI LTKTWEGEWLVSSRSEERLELILRVFRLFKPLAKIEDKGTKLKNACKEILHGNDDEVLREAIHSGDSEYIRKLYALYKEV PYFTDLEKERLYSLIVELKPDVAWDEDEDEDEEGDDDILNRIPEGAILVTRRALNRKKEEFEHLLNVEMPENSKDIGEAQ ERGDLRENAEYKAAMERQVQLQAAIKRLEAEIKSAIILDLTNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKH IISYQSPLAKSLLGKKVGDAAVLNLTGAETRYTVLEIGRFSLQTQED
Sequences:
>Translated_927_residues MSNEISATTESRPASDLDKLTSLFNEEIYVRTDASSIPASKFKIFDDLIEFYKSAGKIDEAKRKIEEYLSEHEDSISARY LLGILSLERGEISDSGLLKNLLESFKVAGKWAIIEHITDQILKYGDQRLALKYKAEALEKLKKNKELKVVLEKLAKHDRK NPEILKKYALSILEENKERAITYLKQAIETFAKTKDYVQLEEIWSIIVSNNHEDLQFFERIERIMLGHRERTRLVGYLYP IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYANHSLLEDFLKMSEIGNNRKPIKVCIANFERNIVFDT NNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQMAITSLKPLKKDHIWVKYYENKEEIVDLFQNNIPDFFKELL TSFNNRMLTADIKSEVAGKFLPALEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFTHQTDANKKL DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQAASEELGDEEIPRHLSEQKIAELIKSLPVNNLTEIS TKIGNVEIKKSYVNLIRKHAHNPEEVLVGILFEVPIKVNKYVFSILEEEGKFDLLNSFIKSAGTRAKEAPEVFIWVAKSI LTKTWEGEWLVSSRSEERLELILRVFRLFKPLAKIEDKGTKLKNACKEILHGNDDEVLREAIHSGDSEYIRKLYALYKEV PYFTDLEKERLYSLIVELKPDVAWDEDEDEDEEGDDDILNRIPEGAILVTRRALNRKKEEFEHLLNVEMPENSKDIGEAQ ERGDLRENAEYKAAMERQVQLQAAIKRLEAEIKSAIILDLTNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKH IISYQSPLAKSLLGKKVGDAAVLNLTGAETRYTVLEIGRFSLQTQED >Mature_926_residues SNEISATTESRPASDLDKLTSLFNEEIYVRTDASSIPASKFKIFDDLIEFYKSAGKIDEAKRKIEEYLSEHEDSISARYL LGILSLERGEISDSGLLKNLLESFKVAGKWAIIEHITDQILKYGDQRLALKYKAEALEKLKKNKELKVVLEKLAKHDRKN PEILKKYALSILEENKERAITYLKQAIETFAKTKDYVQLEEIWSIIVSNNHEDLQFFERIERIMLGHRERTRLVGYLYPI VEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYANHSLLEDFLKMSEIGNNRKPIKVCIANFERNIVFDTN NYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQMAITSLKPLKKDHIWVKYYENKEEIVDLFQNNIPDFFKELLT SFNNRMLTADIKSEVAGKFLPALEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFTHQTDANKKLD IAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQAASEELGDEEIPRHLSEQKIAELIKSLPVNNLTEIST KIGNVEIKKSYVNLIRKHAHNPEEVLVGILFEVPIKVNKYVFSILEEEGKFDLLNSFIKSAGTRAKEAPEVFIWVAKSIL TKTWEGEWLVSSRSEERLELILRVFRLFKPLAKIEDKGTKLKNACKEILHGNDDEVLREAIHSGDSEYIRKLYALYKEVP YFTDLEKERLYSLIVELKPDVAWDEDEDEDEEGDDDILNRIPEGAILVTRRALNRKKEEFEHLLNVEMPENSKDIGEAQE RGDLRENAEYKAAMERQVQLQAAIKRLEAEIKSAIILDLTNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHI ISYQSPLAKSLLGKKVGDAAVLNLTGAETRYTVLEIGRFSLQTQED
Specific function: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary
COG id: COG1747
COG function: function code S; Uncharacterized N-terminal domain of the transcription elongation factor GreA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 GRAD2 (greA associated 2) domain [H]
Homologues:
Organism=Escherichia coli, GI87082225, Length=153, Percent_Identity=35.9477124183007, Blast_Score=96, Evalue=9e-21, Organism=Escherichia coli, GI87082261, Length=147, Percent_Identity=30.6122448979592, Blast_Score=69, Evalue=1e-12,
Paralogues:
None
Copy number: 259 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018151 - InterPro: IPR011990 - InterPro: IPR006359 - InterPro: IPR001437 - InterPro: IPR022691 [H]
Pfam domain/function: PF01272 GreA_GreB; PF03449 GreA_GreB_N [H]
EC number: NA
Molecular weight: Translated: 106939; Mature: 106808
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: PS00830 GREAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNEISATTESRPASDLDKLTSLFNEEIYVRTDASSIPASKFKIFDDLIEFYKSAGKIDE CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHH AKRKIEEYLSEHEDSISARYLLGILSLERGEISDSGLLKNLLESFKVAGKWAIIEHITDQ HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH ILKYGDQRLALKYKAEALEKLKKNKELKVVLEKLAKHDRKNPEILKKYALSILEENKERA HHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH ITYLKQAIETFAKTKDYVQLEEIWSIIVSNNHEDLQFFERIERIMLGHRERTRLVGYLYP HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYANHSLLEDFLKMSEIGN HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC NRKPIKVCIANFERNIVFDTNNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQM CCCCHHHHEECCCCCEEEECCCEEEEECCCCCEEEEECCCCCEEEEEECCCCCCEEEEEE AITSLKPLKKDHIWVKYYENKEEIVDLFQNNIPDFFKELLTSFNNRMLTADIKSEVAGKF HHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHH LPALEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFTHQTDANKKL HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQAASEELGDEEIPRHLS HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH EQKIAELIKSLPVNNLTEISTKIGNVEIKKSYVNLIRKHAHNPEEVLVGILFEVPIKVNK HHHHHHHHHHCCCCCHHHHHHHHCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH YVFSILEEEGKFDLLNSFIKSAGTRAKEAPEVFIWVAKSILTKTWEGEWLVSSRSEERLE HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHH LILRVFRLFKPLAKIEDKGTKLKNACKEILHGNDDEVLREAIHSGDSEYIRKLYALYKEV HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC PYFTDLEKERLYSLIVELKPDVAWDEDEDEDEEGDDDILNRIPEGAILVTRRALNRKKEE CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHH FEHLLNVEMPENSKDIGEAQERGDLRENAEYKAAMERQVQLQAAIKRLEAEIKSAIILDL HHHHHCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE TNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHIISYQSPLAKSLLGKKVGDA CCCCCCEEEEEEEEEECCCCCCCEEEEHHHCCCCCCCHHHHHHHCCHHHHHHHHCCCCCC AVLNLTGAETRYTVLEIGRFSLQTQED EEEEECCCCCHHHHHHHHHHCCCCCCC >Mature Secondary Structure SNEISATTESRPASDLDKLTSLFNEEIYVRTDASSIPASKFKIFDDLIEFYKSAGKIDE CCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHH AKRKIEEYLSEHEDSISARYLLGILSLERGEISDSGLLKNLLESFKVAGKWAIIEHITDQ HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH ILKYGDQRLALKYKAEALEKLKKNKELKVVLEKLAKHDRKNPEILKKYALSILEENKERA HHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH ITYLKQAIETFAKTKDYVQLEEIWSIIVSNNHEDLQFFERIERIMLGHRERTRLVGYLYP HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYANHSLLEDFLKMSEIGN HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC NRKPIKVCIANFERNIVFDTNNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQM CCCCHHHHEECCCCCEEEECCCEEEEECCCCCEEEEECCCCCEEEEEECCCCCCEEEEEE AITSLKPLKKDHIWVKYYENKEEIVDLFQNNIPDFFKELLTSFNNRMLTADIKSEVAGKF HHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHH LPALEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFTHQTDANKKL HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQAASEELGDEEIPRHLS HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH EQKIAELIKSLPVNNLTEISTKIGNVEIKKSYVNLIRKHAHNPEEVLVGILFEVPIKVNK HHHHHHHHHHCCCCCHHHHHHHHCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH YVFSILEEEGKFDLLNSFIKSAGTRAKEAPEVFIWVAKSILTKTWEGEWLVSSRSEERLE HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHH LILRVFRLFKPLAKIEDKGTKLKNACKEILHGNDDEVLREAIHSGDSEYIRKLYALYKEV HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC PYFTDLEKERLYSLIVELKPDVAWDEDEDEDEEGDDDILNRIPEGAILVTRRALNRKKEE CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHH FEHLLNVEMPENSKDIGEAQERGDLRENAEYKAAMERQVQLQAAIKRLEAEIKSAIILDL HHHHHCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE TNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHIISYQSPLAKSLLGKKVGDA CCCCCCEEEEEEEEEECCCCCCCEEEEHHHCCCCCCCHHHHHHHCCHHHHHHHHCCCCCC AVLNLTGAETRYTVLEIGRFSLQTQED EEEEECCCCCHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9403685 [H]