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The map label for this gene is tolQ [H]

Identifier: 116328961

GI number: 116328961

Start: 2803651

End: 2804691

Strand: Direct

Name: tolQ [H]

Synonym: LBL_2362

Alternate gene names: 116328961

Gene position: 2803651-2804691 (Clockwise)

Preceding gene: 116328960

Following gene: 116328962

Centisome position: 77.57

GC content: 40.83

Gene sequence:

>1041_bases
ATGAAATTTTCCTTTATAAAAAAAGAATTTAAGTGGATAATGATTGCGCTGATCATCTCGGGACTCATTTCTTTTTCCAC
GTCCGTATTATTCGCACAAAATAAAATTTCGGAAGCAACCAAGACGGAAGCACCTGCATCCACTCCGACAATTCAAGAAA
CAAAAACCGAAACACCCGTTCAAACAACGGATAAAAGTTGGGGATTTGTGGATCTTTTTCTTCTAGGCGGTTGGACTATG
TACCCGTTAGCGTTTTCTTCGATCGTCGCTTTGGGAATCATCTTTGAACGAATTTATTTCTTAGCAACGGCAAAACTTCT
TCCGAAAGGTTATAATATCGATTTGGGAGAAACCATGGATGCTAAAGGTTTAAATGCAGTCCAAGGTTTTTTTGACGAAA
GAAAAGACTACAAAATCACTCAAATTCTTTCGGGCGGAATCGACGTATCTTCCGGAGACGCTGAAATTTTCGCAAAAGGT
GTGGAAAGAGAAGCCGCGGAAATAATTACGGTTTTGGAAAGAGGACTCGTAATTCTTGCTGCGGTTTCCACGATCGCCCC
TTTAATCGGATTTTTAGGAACGGTTTCCGGTATGATCAACGCGTTCGACGCAATCGCCAACGCAGACCAAGTAAACGCAA
AAGTGGTTGCCGGCGGAATCAAGGAAGCATTGATTACGACGGCGGCAGGCTTAATCGTAGCAATTCCAGCAATGACGTTC
CATCAATACCTAACCTCCAGAATCGACGGTTTTACTTCCGAAATTGAAGAAGCAGCCAACAGGATTTATAAGGAATTCTT
AAAAGGTTTAAACCTTTTATCAACCACTTATGATCCGAATCAAAAAGAAACGCAATTTAGAAGAAATATCGGCATCTTCG
ATGTCGGATATCGCATTTCTCTTACTGGTGTTTTTTATGGTAACAGCGGTATTCTTCGTAAAAGAAGGATTGAACGTTCA
GCTTCCCAGAAAAAATTCCAATCCGACTTTAGTCCTTCGAGAAAACATCTACGAGATTCTGATCGTAGGGGATTTAGTTA
A

Upstream 100 bases:

>100_bases
AAAATAAAGTTTCCCCAAAATTTTAGATCCGTAATTCTTTTGTAATTATCCGGTAACAAATCAAAAGTATATTACGGAAA
CATTTAAATCGGAGACATCG

Downstream 100 bases:

>100_bases
GATGAAGAATAAATCGATCGGAACGAAAGAATATCGAAACCTAACGGATTTCAGAGAAGAACTCAATCTGATGGAAATTT
CCGACATAGGCAACAAAGTC

Product: transport protein, TolQ-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKFSFIKKEFKWIMIALIISGLISFSTSVLFAQNKISEATKTEAPASTPTIQETKTETPVQTTDKSWGFVDLFLLGGWTM
YPLAFSSIVALGIIFERIYFLATAKLLPKGYNIDLGETMDAKGLNAVQGFFDERKDYKITQILSGGIDVSSGDAEIFAKG
VEREAAEIITVLERGLVILAAVSTIAPLIGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIPAMTF
HQYLTSRIDGFTSEIEEAANRIYKEFLKGLNLLSTTYDPNQKETQFRRNIGIFDVGYRISLTGVFYGNSGILRKRRIERS
ASQKKFQSDFSPSRKHLRDSDRRGFS

Sequences:

>Translated_346_residues
MKFSFIKKEFKWIMIALIISGLISFSTSVLFAQNKISEATKTEAPASTPTIQETKTETPVQTTDKSWGFVDLFLLGGWTM
YPLAFSSIVALGIIFERIYFLATAKLLPKGYNIDLGETMDAKGLNAVQGFFDERKDYKITQILSGGIDVSSGDAEIFAKG
VEREAAEIITVLERGLVILAAVSTIAPLIGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIPAMTF
HQYLTSRIDGFTSEIEEAANRIYKEFLKGLNLLSTTYDPNQKETQFRRNIGIFDVGYRISLTGVFYGNSGILRKRRIERS
ASQKKFQSDFSPSRKHLRDSDRRGFS
>Mature_346_residues
MKFSFIKKEFKWIMIALIISGLISFSTSVLFAQNKISEATKTEAPASTPTIQETKTETPVQTTDKSWGFVDLFLLGGWTM
YPLAFSSIVALGIIFERIYFLATAKLLPKGYNIDLGETMDAKGLNAVQGFFDERKDYKITQILSGGIDVSSGDAEIFAKG
VEREAAEIITVLERGLVILAAVSTIAPLIGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIPAMTF
HQYLTSRIDGFTSEIEEAANRIYKEFLKGLNLLSTTYDPNQKETQFRRNIGIFDVGYRISLTGVFYGNSGILRKRRIERS
ASQKKFQSDFSPSRKHLRDSDRRGFS

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=120, Percent_Identity=37.5, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786958, Length=78, Percent_Identity=43.5897435897436, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 38097; Mature: 38097

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSFIKKEFKWIMIALIISGLISFSTSVLFAQNKISEATKTEAPASTPTIQETKTETPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QTTDKSWGFVDLFLLGGWTMYPLAFSSIVALGIIFERIYFLATAKLLPKGYNIDLGETMD
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AKGLNAVQGFFDERKDYKITQILSGGIDVSSGDAEIFAKGVEREAAEIITVLERGLVILA
CCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSTIAPLIGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIPAMTF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQYLTSRIDGFTSEIEEAANRIYKEFLKGLNLLSTTYDPNQKETQFRRNIGIFDVGYRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCEEEE
LTGVFYGNSGILRKRRIERSASQKKFQSDFSPSRKHLRDSDRRGFS
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKFSFIKKEFKWIMIALIISGLISFSTSVLFAQNKISEATKTEAPASTPTIQETKTETPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QTTDKSWGFVDLFLLGGWTMYPLAFSSIVALGIIFERIYFLATAKLLPKGYNIDLGETMD
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AKGLNAVQGFFDERKDYKITQILSGGIDVSSGDAEIFAKGVEREAAEIITVLERGLVILA
CCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSTIAPLIGFLGTVSGMINAFDAIANADQVNAKVVAGGIKEALITTAAGLIVAIPAMTF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQYLTSRIDGFTSEIEEAANRIYKEFLKGLNLLSTTYDPNQKETQFRRNIGIFDVGYRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCEEEE
LTGVFYGNSGILRKRRIERSASQKKFQSDFSPSRKHLRDSDRRGFS
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]