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The map label for this gene is dapL [H]

Identifier: 116328950

GI number: 116328950

Start: 2784647

End: 2785873

Strand: Direct

Name: dapL [H]

Synonym: LBL_2347

Alternate gene names: 116328950

Gene position: 2784647-2785873 (Clockwise)

Preceding gene: 116328949

Following gene: 116328951

Centisome position: 77.04

GC content: 46.21

Gene sequence:

>1227_bases
ATGGCGAACATCAATGAGAATTATTTAAAATTAAAAGCGGGATATTTGTTTCCTGAAATTTCGAAACGCGTAAAGACTTA
CTCCGAAAAAAACCCTTCCGCGAAAATCATCCGCTTGGGAATCGGAGACGTAACTCTTCCGATCGTTCCTTCGGTCGTCG
ACGCGATGATCGCGGCTTCCAAAGAGATGGGAACAGCGGGAGGCTTTCACGGTTACGGACCGGAACAAGGATATTCCTTT
TTGCTAAAGTCGATTGCCAATAACGACTACGGTTCCCTCGGAATCAAAATCGACGAAAGCGAGATCTTCGTTTCCGACGG
ATCTAAATGCGATTGTGGTAATATTCAAGAAATCTTTTCCACCGATGCGAAGATCGCCGTCTCCGATCCCGTTTATCCCG
TGTATGTGGATACTAACGTAATGGCCGGAAGAACGGGCGAGATCGGTGCGGACGGAAGGTATTCCAATCTGATCTATATG
CCCGCGACCAAAGAGAACGGATTTCAACCGGAGATTCCGAAAGAAAAAGCGGACATCATCTATCTTTGTTATCCGAACAA
CCCGACCGGAACCGTGACCACAAAAAAAGCCCTCAGGGCTTGGGTGGAATATGCGAAGAAAAACAATTCCATCATTCTTT
ACGATTCCGCATACGAGGCGTTTATCAGCGAGCCGGGCGTTCCCCGTTCGATCTATGAAGTTGCAGGAGCCAAAGAAGTT
GCGATCGAATTCCGCTCCTTTTCCAAAACCGCGGGATTTACAGGATTACGTTGTGCTTATATAGTAATTCCAAAAGAACT
CAAAGGCAGGACTCGCGGCGGAGAGGAAGTCAGCATCAATTCTCTTTGGAGTAGAAGACATACGACGAAGTTCAACGGGG
TTTCGTATGTGACTCAAAAAGGTGCAGAAGCTTGTTATTCTCCTCAAGGAAAAAAAGAAATCCAAGCTTCGATCGCGTAT
TATATGTCGAACGCCGCGAAAATCCGCGAAGGTTTGAAAAAAGCTGGTTATGAAGTGTTCGGAGGAGTCAACGCCCCTTA
CATTTGGTTGAAAACTTCGGACAATCTTTCTTCTTGGGATTTCTTTGATAGACTTTTAGATAAAGCACAAGTGGTCGGAA
CTCCGGGCTCCGGTTTTGGTCCTGCGGGAGAAGGTTATTTCCGTCTCAGCGCCTTTGGCAAAAAAGAGGACGTGGAAGAA
GCGATTGCACGAATTTCTTTTCTTTGA

Upstream 100 bases:

>100_bases
GGATATTATTGCTGGCACCTCGGAGAAGAGGACCTTCTTTACGAACACGGTTACGAAGAAGGTTTTGCCGGAAGAAAACC
AATCGATAGGAATAAAGAAA

Downstream 100 bases:

>100_bases
AGTTCAATCGAGAAGATCTAAATTCTCAAATCTTTATATGATTTTTAAAAAGTAGGAACTCTTACTTTTTAAAAATCGAT
CCTTTGAAAAGTTCTTGGCA

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MANINENYLKLKAGYLFPEISKRVKTYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMIAASKEMGTAGGFHGYGPEQGYSF
LLKSIANNDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFSTDAKIAVSDPVYPVYVDTNVMAGRTGEIGADGRYSNLIYM
PATKENGFQPEIPKEKADIIYLCYPNNPTGTVTTKKALRAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVAGAKEV
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRGGEEVSINSLWSRRHTTKFNGVSYVTQKGAEACYSPQGKKEIQASIAY
YMSNAAKIREGLKKAGYEVFGGVNAPYIWLKTSDNLSSWDFFDRLLDKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEE
AIARISFL

Sequences:

>Translated_408_residues
MANINENYLKLKAGYLFPEISKRVKTYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMIAASKEMGTAGGFHGYGPEQGYSF
LLKSIANNDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFSTDAKIAVSDPVYPVYVDTNVMAGRTGEIGADGRYSNLIYM
PATKENGFQPEIPKEKADIIYLCYPNNPTGTVTTKKALRAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVAGAKEV
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRGGEEVSINSLWSRRHTTKFNGVSYVTQKGAEACYSPQGKKEIQASIAY
YMSNAAKIREGLKKAGYEVFGGVNAPYIWLKTSDNLSSWDFFDRLLDKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEE
AIARISFL
>Mature_407_residues
ANINENYLKLKAGYLFPEISKRVKTYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMIAASKEMGTAGGFHGYGPEQGYSFL
LKSIANNDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFSTDAKIAVSDPVYPVYVDTNVMAGRTGEIGADGRYSNLIYMP
ATKENGFQPEIPKEKADIIYLCYPNNPTGTVTTKKALRAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVAGAKEVA
IEFRSFSKTAGFTGLRCAYIVIPKELKGRTRGGEEVSINSLWSRRHTTKFNGVSYVTQKGAEACYSPQGKKEIQASIAYY
MSNAAKIREGLKKAGYEVFGGVNAPYIWLKTSDNLSSWDFFDRLLDKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEEA
IARISFL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=376, Percent_Identity=23.936170212766, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44654; Mature: 44523

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANINENYLKLKAGYLFPEISKRVKTYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMIAAS
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEHHHHHHHHHHHHHHH
KEMGTAGGFHGYGPEQGYSFLLKSIANNDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFS
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCCCCHHHHHC
TDAKIAVSDPVYPVYVDTNVMAGRTGEIGADGRYSNLIYMPATKENGFQPEIPKEKADII
CCCEEEECCCEEEEEEECCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
YLCYPNNPTGTVTTKKALRAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVAGAKEV
EEEECCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCHHHHHHCCCHHE
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRGGEEVSINSLWSRRHTTKFNGVSYVTQK
EHHHHHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHH
GAEACYSPQGKKEIQASIAYYMSNAAKIREGLKKAGYEVFGGVNAPYIWLKTSDNLSSWD
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHH
FFDRLLDKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEEAIARISFL
HHHHHHHHHEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANINENYLKLKAGYLFPEISKRVKTYSEKNPSAKIIRLGIGDVTLPIVPSVVDAMIAAS
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCEEHHHHHHHHHHHHHHH
KEMGTAGGFHGYGPEQGYSFLLKSIANNDYGSLGIKIDESEIFVSDGSKCDCGNIQEIFS
HHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEECCCCCCCCCHHHHHC
TDAKIAVSDPVYPVYVDTNVMAGRTGEIGADGRYSNLIYMPATKENGFQPEIPKEKADII
CCCEEEECCCEEEEEEECCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEE
YLCYPNNPTGTVTTKKALRAWVEYAKKNNSIILYDSAYEAFISEPGVPRSIYEVAGAKEV
EEEECCCCCCCEEHHHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCHHHHHHCCCHHE
AIEFRSFSKTAGFTGLRCAYIVIPKELKGRTRGGEEVSINSLWSRRHTTKFNGVSYVTQK
EHHHHHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHH
GAEACYSPQGKKEIQASIAYYMSNAAKIREGLKKAGYEVFGGVNAPYIWLKTSDNLSSWD
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHH
FFDRLLDKAQVVGTPGSGFGPAGEGYFRLSAFGKKEDVEEAIARISFL
HHHHHHHHHEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA