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The map label for this gene is pdxA [H]

Identifier: 116328930

GI number: 116328930

Start: 2747907

End: 2748857

Strand: Reverse

Name: pdxA [H]

Synonym: LBL_2325

Alternate gene names: 116328930

Gene position: 2748857-2747907 (Counterclockwise)

Preceding gene: 116328931

Following gene: 116328929

Centisome position: 76.05

GC content: 43.95

Gene sequence:

>951_bases
GTGAAGCGGATCTTGATTACGGAAGGCGATCCTTGTGGAATCGGTCCGGAAATTTTCGTTCATTCCCTTTTTCTTTTAAG
AAAAATCTCCAAAATAAGACCGATCGTTTACTTTCATTCGGGTAAGTTTCCTCTCCCGAAAGAATTCGTTTCGATTTCTT
CTTCCTCCGAAATCCTAAAAAAGGGTTTGTTTGCGATTGGCCACGATTCTCTTTCCAAAAAAGAAGTCTCTTCTTTGAAA
TTCGGTAGACCTTCCGCTTTGTCGGGAAAATCTGCGTTAGCGGCTCTTGTACTCTCGATAGAGTTTCAAAAAGAAGGCGG
AGGGGATTTGATTACTCTTCCCCTCAGCAAAGAATGGGTGATTGCGTCCGGTGTTTCCACGTTTCGAGGTCATACGGAAT
TTTTAGCGGAGGCCTATCGGACAAAAACGTTTATGCTTATGTCCGGAAACGATCTTCAGGTACTTCCTCTCACGACTCAT
ATTCCTCTTGTAAAAGTTCCCGAGTTTTTGAAAGAGATCGATCTGAAATCGCTTGCAAATTCTATTCTTTCCTGCGAGAA
AATCGATCTCCAAAAACCGATCGCATTTCTCGGCTTGAATCCGCATGCGGGAGAAGGTGGTAAAATCGGTAAAGAGGAGG
AAGAAATTCTAGTACCGATGATTCGATCCTTAAAAAGGCAAGGTTTGAAAGTGGAAGGGCCTCTTTCCGCCGATTCTGTA
TTCGGCGAGTCCGCACGAAAAAAATTCGGTCTGCATCTTGCTTGTTATCACGACCAGGGTTTGATTCCTTTCAAAATGTG
GGAAGGAAAAAAGGGCGTGAATCTAACTTTGGGTCTCCCGTTTATCCGAGTTTCACCGGATCACGGAACGGCCTTTGACA
TTGCCGGGAAAGGGCTTGCAGATTCGACGAGCTTTATGGAATGTCTGAATCGGATTTTACAATATTCATGA

Upstream 100 bases:

>100_bases
TCGAAAAAATCTTCGGAAAACAATCCGGAGCGAGAGAATAATTTGGAAGGTTTTCCTTTCGGAAAAAAATTTCCGGAATA
AAAGCCGATTTCCCGAAACA

Downstream 100 bases:

>100_bases
ATCGTATTACAACCGAGGTTTTATGCCGGGACTTTTAGAACAGATTGTATTTCCGATTTTTCTTTTTTGGTTCTGCGGAC
TGACTCTACTTTTGTTTCGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKRILITEGDPCGIGPEIFVHSLFLLRKISKIRPIVYFHSGKFPLPKEFVSISSSSEILKKGLFAIGHDSLSKKEVSSLK
FGRPSALSGKSALAALVLSIEFQKEGGGDLITLPLSKEWVIASGVSTFRGHTEFLAEAYRTKTFMLMSGNDLQVLPLTTH
IPLVKVPEFLKEIDLKSLANSILSCEKIDLQKPIAFLGLNPHAGEGGKIGKEEEEILVPMIRSLKRQGLKVEGPLSADSV
FGESARKKFGLHLACYHDQGLIPFKMWEGKKGVNLTLGLPFIRVSPDHGTAFDIAGKGLADSTSFMECLNRILQYS

Sequences:

>Translated_316_residues
MKRILITEGDPCGIGPEIFVHSLFLLRKISKIRPIVYFHSGKFPLPKEFVSISSSSEILKKGLFAIGHDSLSKKEVSSLK
FGRPSALSGKSALAALVLSIEFQKEGGGDLITLPLSKEWVIASGVSTFRGHTEFLAEAYRTKTFMLMSGNDLQVLPLTTH
IPLVKVPEFLKEIDLKSLANSILSCEKIDLQKPIAFLGLNPHAGEGGKIGKEEEEILVPMIRSLKRQGLKVEGPLSADSV
FGESARKKFGLHLACYHDQGLIPFKMWEGKKGVNLTLGLPFIRVSPDHGTAFDIAGKGLADSTSFMECLNRILQYS
>Mature_316_residues
MKRILITEGDPCGIGPEIFVHSLFLLRKISKIRPIVYFHSGKFPLPKEFVSISSSSEILKKGLFAIGHDSLSKKEVSSLK
FGRPSALSGKSALAALVLSIEFQKEGGGDLITLPLSKEWVIASGVSTFRGHTEFLAEAYRTKTFMLMSGNDLQVLPLTTH
IPLVKVPEFLKEIDLKSLANSILSCEKIDLQKPIAFLGLNPHAGEGGKIGKEEEEILVPMIRSLKRQGLKVEGPLSADSV
FGESARKKFGLHLACYHDQGLIPFKMWEGKKGVNLTLGLPFIRVSPDHGTAFDIAGKGLADSTSFMECLNRILQYS

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=332, Percent_Identity=33.433734939759, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34606; Mature: 34606

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILITEGDPCGIGPEIFVHSLFLLRKISKIRPIVYFHSGKFPLPKEFVSISSSSEILK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHH
KGLFAIGHDSLSKKEVSSLKFGRPSALSGKSALAALVLSIEFQKEGGGDLITLPLSKEWV
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHEEEHEEEEEECCCCCCEEEECCCCCEE
IASGVSTFRGHTEFLAEAYRTKTFMLMSGNDLQVLPLTTHIPLVKVPEFLKEIDLKSLAN
EECCCHHHCCHHHHHHHHHCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
SILSCEKIDLQKPIAFLGLNPHAGEGGKIGKEEEEILVPMIRSLKRQGLKVEGPLSADSV
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHH
FGESARKKFGLHLACYHDQGLIPFKMWEGKKGVNLTLGLPFIRVSPDHGTAFDIAGKGLA
HHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCEEEECCCEEEECCCCCCEEEECCCCCC
DSTSFMECLNRILQYS
CCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRILITEGDPCGIGPEIFVHSLFLLRKISKIRPIVYFHSGKFPLPKEFVSISSSSEILK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHH
KGLFAIGHDSLSKKEVSSLKFGRPSALSGKSALAALVLSIEFQKEGGGDLITLPLSKEWV
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCHHHHEEEHEEEEEECCCCCCEEEECCCCCEE
IASGVSTFRGHTEFLAEAYRTKTFMLMSGNDLQVLPLTTHIPLVKVPEFLKEIDLKSLAN
EECCCHHHCCHHHHHHHHHCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
SILSCEKIDLQKPIAFLGLNPHAGEGGKIGKEEEEILVPMIRSLKRQGLKVEGPLSADSV
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHH
FGESARKKFGLHLACYHDQGLIPFKMWEGKKGVNLTLGLPFIRVSPDHGTAFDIAGKGLA
HHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCEEEECCCEEEECCCCCCEEEECCCCCC
DSTSFMECLNRILQYS
CCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA