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The map label for this gene is 116328900

Identifier: 116328900

GI number: 116328900

Start: 2711842

End: 2713824

Strand: Reverse

Name: 116328900

Synonym: LBL_2291

Alternate gene names: NA

Gene position: 2713824-2711842 (Counterclockwise)

Preceding gene: 116328901

Following gene: 116328898

Centisome position: 75.08

GC content: 41.6

Gene sequence:

>1983_bases
ATGGGTCAGGAATTTCCTAAATATATAGTCACGGACTTTCGTTCTATCGTTAAAAGGTTGGATCCGATCGTTCTCCGTTT
AGGAATACAATTTTTAAATCTTAAAGAATTCATCCAGTCCGAACCTATTCTCGATTCCATCGGATTCTTAAACGTCGTTT
TCTATTTGTCGGCTTCTCGTCTCAAAGAAACTCAAAAAGAAATTCATGAACGGTTTCAGAAAAATCCGCTGATCTTAAGC
CGTTTCATTTTAAACGAAAACTTGGATTATGTTCACTCGGAAGACCTAAAAATCGAGGAAGACCTGATCTTTTCGATCCT
GCCGGAATCGTCTTCGGATATGATCTTAAATAAAACCTTTCTCAACGCATTTACTCAGCTTCAGATGATCACGGATCAGT
TCGATCTTCAACACAAAGTAAACACTACGAAGTACGAGATCTCAAAGCTGACTCAGATTGGAATCAATCTCGCGGATGAA
AAGGACATCAATAAGCTTCTCCGGGAGATTATTTTTAGCGCGAGGGAAATAGCGATCGCCGATTCGGGATCTTTATACCT
CGTGGAAAAGGACGAACAGGGGGTTGTGCGTAATCTTAGGTTTAAAATTTCGTCTATGGATATCAATACGGAGGAATTTT
TACTTCCGATTAATAAATCCAGCGTTGCGGGTTACGTTGCCGCCACGGGAAAAATTTTGAACATCCCGAACGTTTATGAT
CTGCCGAAAGACGCGGAGTATACATTTAACAGCAACTTCGACGTTCTTTCCAATTATCATACGAAATCCATGCTTGTAGT
TCCTATGAAAAACCATAGAGACGAGGTTGTGGGAGTCATTCAACTTATTAACAAGAAAAGGAACTTCAATCAAAAACTGA
CGATTGAGCAGATGAAAGGGGAGGACATTTTTCCTTTCGACGATTATTCCGCTCAGCTTGTGATGAGCGTCGCAGGACAG
GCCGCGGTCGCGATTCAGAACAATCATCTTTTAAAGGAGATTGAGACTCTTTTTGAAGGTTTCGTAACGGCATCCGTAAA
TGCGATCGAAGCCAGGGATCCTACGACGAGCGGTCACTCGTTTAGAGTCGCCATTCTGACGGTCGGTTTGGCGGAAACGG
TGGATTCCATCCGGGAAGGTAAATACGGACAAACTCAATTTTCGAAGGAACAAATCAAAGAAATACGTTATGCATCTTTG
CTTCACGATTTCGGAAAAGTGGGAGTTCGGGAAAAGGTCTTGGTTAAATCCAAAAAACTGGAAGATTACGAACTCGAGCT
GATCCGTTGGAGATTCGAATACATCAAAAAAGACATCGAATCCAAAACACTTCAAAAAAAGATGGATTACTTAAAAAAAA
ACGGGAGTGTCGGCTTCTCCGATTACGAGATCTCTCTCGAATTCGAGCTCCAGGCGGAATACCAAAGGCTCGATCGAATG
TTTCAGGTCGTTGTCAATTCCAACGAACCATCCATATTAGAAGAATCTAATTTTCAAATGCTGGAAGAAATAGCTCAGGT
GAACTATTTCACCACGGGAGGGGACAAGTTGCATTTGATCTCTCCATATGAATTCGGTTTTTTGACGATCAAAAAAGGAT
CTTTGGATCTAGCGGAAAGAAAGGAAATTGAATCTCATGTAGAGCTTACGTTTCAGTTTTTAAGTATGATTCCTTGGACT
GGGGACCTGAAAATGGTTCCTTCCATCGCCCATGCGCATCACGAAAAATTGGACGGCACCGGTTATCCAAGAGGACTTAC
AGCCGATTCGATTCCGGTCCAATCAAAAATTATGGCGATCTCTGATATTTTCGACGCGCTTACCGATAAGGATCGACCCT
ATAAAAGGGCTGTTTCTGTGGAAAGAGCGTTGGATATACTACAAATGGAAGCAAAGGAGAATCATGTTGATCCGGATCTT
CTCAAGATTTTTATCGATGGGAAGATTTATGAAAGTTTATCCAGCTCGGGTTATATCCGTTAA

Upstream 100 bases:

>100_bases
ATACATCTCAAGTTATAGATTTGTTATCTTTTTTTGCAAAATTCGGGGAAAAATTCTCTTTCCTATAAATTCCGGTACTG
TTTGATTGATTCCTGGTAAG

Downstream 100 bases:

>100_bases
TATACAAGAAAAATCACCGCTTTTTTTCGATCGAGATGATTCTGTAATTTTGACTGATGTTTCCTCTTGTAAATCGAAGT
ATCCTTGAAACAATCGTTTC

Product: response regulator

Products: nucleoside 5'-phosphate

Alternate protein names: Metal-Dependent Phosphohydrolase; Response Regulator; PAS/PAC Sensor Protein; Chemotaxis Sensory Transducer Family Protein; HAMP Domain Protein; GAF Domain-Containing Protein; Response Regulator CheB; HD-GYP Domain-Containing Protein; Methyl-Accepting Chemotaxis Protein; Response Regulator Receiver Protein; HD-Domain-Containing Protein; GAF Domain/HD Domain-Containing Protein; Chemotactic Transducer-Related Protein; Diguanylate Cyclase Domain Protein; Two-Component System Response Regulator; HD Domain Protein; Metal Dependent Phosphohydrolase HD Region; PAS Sensor Protein; Two-Component Response Regulator; ABC-Type Amino Acid Transport Signal Transduction Systems; Metal Dependent Phosphohydrolase With Gaf Sensor; HD-GYP/GAF Domain-Containing Protein; Hamp Domain/Gaf Domain/Hd Domain Protein; 3 5'-Cyclic-Nucleotide Phosphodiesterase; Diguanylate Cyclase With PAS/PAC Sensor; GAF Domain/HD Domain Protein; HDIG Domain-Containing Protein; Metal-Dependent Phosphohydrolase HD Subdomain; GAF Containing Protein; Signal Transduction Response Regulator; Diguanylate Cyclase; Replicative DNA Helicase; HD_GYP Domain-Containing Response Regulator; Response Regulator Receiver; Metal Dependent Phophohydrolase; GAF Domain Protein; Two-Component Regulatory System Response Regulator; Sensor Histidine Kinase/GAF Domain-Containing Protein; Metal-Dependent Phosphohydrolase HD Region; Diguanylate Cyclase And Metal Dependent Phosphohydrolase; HD-Hydrolase Domain-Containing Protein; Integral Membrane Protein Two-Component Signal Transducer; HAMP Domain-Containing Protein; Response Regulator/Phosphatase; Chemotaxis Protein; Response Regulator With HD-GYP Domain; Two-Component Response Regulator Fusion Protein; Response Regulator Containing A CheY-Like Receiver Domain; Multi-Sensor Signal Transduction Histidine Kinase

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MGQEFPKYIVTDFRSIVKRLDPIVLRLGIQFLNLKEFIQSEPILDSIGFLNVVFYLSASRLKETQKEIHERFQKNPLILS
RFILNENLDYVHSEDLKIEEDLIFSILPESSSDMILNKTFLNAFTQLQMITDQFDLQHKVNTTKYEISKLTQIGINLADE
KDINKLLREIIFSAREIAIADSGSLYLVEKDEQGVVRNLRFKISSMDINTEEFLLPINKSSVAGYVAATGKILNIPNVYD
LPKDAEYTFNSNFDVLSNYHTKSMLVVPMKNHRDEVVGVIQLINKKRNFNQKLTIEQMKGEDIFPFDDYSAQLVMSVAGQ
AAVAIQNNHLLKEIETLFEGFVTASVNAIEARDPTTSGHSFRVAILTVGLAETVDSIREGKYGQTQFSKEQIKEIRYASL
LHDFGKVGVREKVLVKSKKLEDYELELIRWRFEYIKKDIESKTLQKKMDYLKKNGSVGFSDYEISLEFELQAEYQRLDRM
FQVVVNSNEPSILEESNFQMLEEIAQVNYFTTGGDKLHLISPYEFGFLTIKKGSLDLAERKEIESHVELTFQFLSMIPWT
GDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPVQSKIMAISDIFDALTDKDRPYKRAVSVERALDILQMEAKENHVDPDL
LKIFIDGKIYESLSSSGYIR

Sequences:

>Translated_660_residues
MGQEFPKYIVTDFRSIVKRLDPIVLRLGIQFLNLKEFIQSEPILDSIGFLNVVFYLSASRLKETQKEIHERFQKNPLILS
RFILNENLDYVHSEDLKIEEDLIFSILPESSSDMILNKTFLNAFTQLQMITDQFDLQHKVNTTKYEISKLTQIGINLADE
KDINKLLREIIFSAREIAIADSGSLYLVEKDEQGVVRNLRFKISSMDINTEEFLLPINKSSVAGYVAATGKILNIPNVYD
LPKDAEYTFNSNFDVLSNYHTKSMLVVPMKNHRDEVVGVIQLINKKRNFNQKLTIEQMKGEDIFPFDDYSAQLVMSVAGQ
AAVAIQNNHLLKEIETLFEGFVTASVNAIEARDPTTSGHSFRVAILTVGLAETVDSIREGKYGQTQFSKEQIKEIRYASL
LHDFGKVGVREKVLVKSKKLEDYELELIRWRFEYIKKDIESKTLQKKMDYLKKNGSVGFSDYEISLEFELQAEYQRLDRM
FQVVVNSNEPSILEESNFQMLEEIAQVNYFTTGGDKLHLISPYEFGFLTIKKGSLDLAERKEIESHVELTFQFLSMIPWT
GDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPVQSKIMAISDIFDALTDKDRPYKRAVSVERALDILQMEAKENHVDPDL
LKIFIDGKIYESLSSSGYIR
>Mature_659_residues
GQEFPKYIVTDFRSIVKRLDPIVLRLGIQFLNLKEFIQSEPILDSIGFLNVVFYLSASRLKETQKEIHERFQKNPLILSR
FILNENLDYVHSEDLKIEEDLIFSILPESSSDMILNKTFLNAFTQLQMITDQFDLQHKVNTTKYEISKLTQIGINLADEK
DINKLLREIIFSAREIAIADSGSLYLVEKDEQGVVRNLRFKISSMDINTEEFLLPINKSSVAGYVAATGKILNIPNVYDL
PKDAEYTFNSNFDVLSNYHTKSMLVVPMKNHRDEVVGVIQLINKKRNFNQKLTIEQMKGEDIFPFDDYSAQLVMSVAGQA
AVAIQNNHLLKEIETLFEGFVTASVNAIEARDPTTSGHSFRVAILTVGLAETVDSIREGKYGQTQFSKEQIKEIRYASLL
HDFGKVGVREKVLVKSKKLEDYELELIRWRFEYIKKDIESKTLQKKMDYLKKNGSVGFSDYEISLEFELQAEYQRLDRMF
QVVVNSNEPSILEESNFQMLEEIAQVNYFTTGGDKLHLISPYEFGFLTIKKGSLDLAERKEIESHVELTFQFLSMIPWTG
DLKMVPSIAHAHHEKLDGTGYPRGLTADSIPVQSKIMAISDIFDALTDKDRPYKRAVSVERALDILQMEAKENHVDPDLL
KIFIDGKIYESLSSSGYIR

Specific function: Unknown

COG id: COG2206

COG function: function code T; HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI61744435, Length=151, Percent_Identity=33.7748344370861, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI61744430, Length=151, Percent_Identity=33.7748344370861, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI61744432, Length=151, Percent_Identity=33.7748344370861, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226246591, Length=143, Percent_Identity=34.965034965035, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI4505657, Length=143, Percent_Identity=34.965034965035, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI219802706, Length=143, Percent_Identity=34.965034965035, Blast_Score=78, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.4.17

Molecular weight: Translated: 75643; Mature: 75511

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQEFPKYIVTDFRSIVKRLDPIVLRLGIQFLNLKEFIQSEPILDSIGFLNVVFYLSASR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LKETQKEIHERFQKNPLILSRFILNENLDYVHSEDLKIEEDLIFSILPESSSDMILNKTF
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEECHHHEEEECCCCCCCEEEHHHH
LNAFTQLQMITDQFDLQHKVNTTKYEISKLTQIGINLADEKDINKLLREIIFSAREIAIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEE
DSGSLYLVEKDEQGVVRNLRFKISSMDINTEEFLLPINKSSVAGYVAATGKILNIPNVYD
CCCCEEEEECCCCCHHHHHEEEEEECCCCHHHEEEECCCCCCCEEEEECCEEEECCCCCC
LPKDAEYTFNSNFDVLSNYHTKSMLVVPMKNHRDEVVGVIQLINKKRNFNQKLTIEQMKG
CCCCCCEEECCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
EDIFPFDDYSAQLVMSVAGQAAVAIQNNHLLKEIETLFEGFVTASVNAIEARDPTTSGHS
CCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCC
FRVAILTVGLAETVDSIREGKYGQTQFSKEQIKEIRYASLLHDFGKVGVREKVLVKSKKL
EEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
EDYELELIRWRFEYIKKDIESKTLQKKMDYLKKNGSVGFSDYEISLEFELQAEYQRLDRM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECHHHHHHHHH
FQVVVNSNEPSILEESNFQMLEEIAQVNYFTTGGDKLHLISPYEFGFLTIKKGSLDLAER
HHHHHCCCCCCCCCCCCHHHHHHHHHCCEEECCCCEEEEECCCCCCEEEEECCCCCHHHH
KEIESHVELTFQFLSMIPWTGDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPVQSKIMAI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SDIFDALTDKDRPYKRAVSVERALDILQMEAKENHVDPDLLKIFIDGKIYESLSSSGYIR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCHHHHHHCCCCCCC
>Mature Secondary Structure 
GQEFPKYIVTDFRSIVKRLDPIVLRLGIQFLNLKEFIQSEPILDSIGFLNVVFYLSASR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LKETQKEIHERFQKNPLILSRFILNENLDYVHSEDLKIEEDLIFSILPESSSDMILNKTF
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEECHHHEEEECCCCCCCEEEHHHH
LNAFTQLQMITDQFDLQHKVNTTKYEISKLTQIGINLADEKDINKLLREIIFSAREIAIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHEEEE
DSGSLYLVEKDEQGVVRNLRFKISSMDINTEEFLLPINKSSVAGYVAATGKILNIPNVYD
CCCCEEEEECCCCCHHHHHEEEEEECCCCHHHEEEECCCCCCCEEEEECCEEEECCCCCC
LPKDAEYTFNSNFDVLSNYHTKSMLVVPMKNHRDEVVGVIQLINKKRNFNQKLTIEQMKG
CCCCCCEEECCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
EDIFPFDDYSAQLVMSVAGQAAVAIQNNHLLKEIETLFEGFVTASVNAIEARDPTTSGHS
CCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCC
FRVAILTVGLAETVDSIREGKYGQTQFSKEQIKEIRYASLLHDFGKVGVREKVLVKSKKL
EEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
EDYELELIRWRFEYIKKDIESKTLQKKMDYLKKNGSVGFSDYEISLEFELQAEYQRLDRM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECHHHHHHHHH
FQVVVNSNEPSILEESNFQMLEEIAQVNYFTTGGDKLHLISPYEFGFLTIKKGSLDLAER
HHHHHCCCCCCCCCCCCHHHHHHHHHCCEEECCCCEEEEECCCCCCEEEEECCCCCHHHH
KEIESHVELTFQFLSMIPWTGDLKMVPSIAHAHHEKLDGTGYPRGLTADSIPVQSKIMAI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SDIFDALTDKDRPYKRAVSVERALDILQMEAKENHVDPDLLKIFIDGKIYESLSSSGYIR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside 3',5'-cyclic phosphate; H2O

Specific reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA