Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 116328803

GI number: 116328803

Start: 2560607

End: 2561581

Strand: Direct

Name: fabH [H]

Synonym: LBL_2178

Alternate gene names: 116328803

Gene position: 2560607-2561581 (Clockwise)

Preceding gene: 116328802

Following gene: 116328804

Centisome position: 70.84

GC content: 46.15

Gene sequence:

>975_bases
ATGAGTGGAAAAAATCAAACGTCGAACGGAATCAGGATCACCGGCTTCGGCCACTATCTTCCGGAACGAATCGTGACTAA
CGAGGAAATTCGTTCCCGTTTGAAATTTCCGGAAATGCATCCCGCCGAAAAAGCAGTGATTGGAAATATAGGAGTCAACG
AAAGAAGAAGAGCCAACGAAACCGAAACCGCAATGTTCATGGCTTCGAAAGTGGCGGAAATGGCTTTAAAAGACGCAGGA
AAAAAACCGGAAGATGTGGATCTTTATATTCTCGCGAATTGGACCGATCGTTATTATCTTCCCGATTTAGCGCCCCAAGC
ATCGAAACTTTCCGGAACGTCCAACGCCCTCGCTTTCGACGTTAGTACGGCTTGTACGGGTTTCGTTCATGGAGTTCAAA
CGGCGTCCGCATATTTGGGAACGAACAAATTTAAAAATGCTCTCGTTATCGGAAGTGAACGATTTTCCGTCAGAACCAGA
ATGGGAGGTTACGGGGAATTTACCGCGGGAGACGCAGCGGCAGGCGTTTTTTTAGAATATACGGGAGATAAAAATTTCGG
GATCATCGACTCCTTTCTGCAAGACGACGGCGACCTTTCAGGTATCATCGTAACCGGACCTCCTCCAACGAGTTATGTGA
AAAGTTACCCCGAACTCGTGAGCAAAGCGGCGGATCTCACTCTCAAGTCTATGGATCTACTCTTGGAAAAAAACGGTCTT
ACTATAGACGATGTGGACTGGGTCGTCCCTCATCCCGGAACGGACGTAGTCGTTCAAGACGTTCTCAAAAGGACTAAATT
TCCGAGGGAAAAAATTCTTATGAACTTTGAAAGAGTCGGAAATACTTCCGCCGCCTCGATCCCGATCGTATTATCAGAAT
ATTATTATAAAGGAAAGTTTAAAAAAGGAGATTTATTCCTTACCCCCGCCGTAGGAGGCGGATTTTATTGGGGAGGGCTC
TTATTCCGTCTCTGA

Upstream 100 bases:

>100_bases
TTTACGCGAGTTGGATCCGGAAAAGATTTACATAGAACAATTTATGGTATATACAAGACTTCCATAATAAAATGAAATTC
GAATTTAGTAGAGGCCCTTT

Downstream 100 bases:

>100_bases
ACGTAATAGGAACATCGATACGTATGAAAATAGAAGGTTACGAAATAAAAGAAAAGATGAACACTGACTCGTCCACGGAG
GTTTACAAGGCAGTACGATC

Product: 3-oxoacyl-[acyl-carrier protein] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSGKNQTSNGIRITGFGHYLPERIVTNEEIRSRLKFPEMHPAEKAVIGNIGVNERRRANETETAMFMASKVAEMALKDAG
KKPEDVDLYILANWTDRYYLPDLAPQASKLSGTSNALAFDVSTACTGFVHGVQTASAYLGTNKFKNALVIGSERFSVRTR
MGGYGEFTAGDAAAGVFLEYTGDKNFGIIDSFLQDDGDLSGIIVTGPPPTSYVKSYPELVSKAADLTLKSMDLLLEKNGL
TIDDVDWVVPHPGTDVVVQDVLKRTKFPREKILMNFERVGNTSAASIPIVLSEYYYKGKFKKGDLFLTPAVGGGFYWGGL
LFRL

Sequences:

>Translated_324_residues
MSGKNQTSNGIRITGFGHYLPERIVTNEEIRSRLKFPEMHPAEKAVIGNIGVNERRRANETETAMFMASKVAEMALKDAG
KKPEDVDLYILANWTDRYYLPDLAPQASKLSGTSNALAFDVSTACTGFVHGVQTASAYLGTNKFKNALVIGSERFSVRTR
MGGYGEFTAGDAAAGVFLEYTGDKNFGIIDSFLQDDGDLSGIIVTGPPPTSYVKSYPELVSKAADLTLKSMDLLLEKNGL
TIDDVDWVVPHPGTDVVVQDVLKRTKFPREKILMNFERVGNTSAASIPIVLSEYYYKGKFKKGDLFLTPAVGGGFYWGGL
LFRL
>Mature_323_residues
SGKNQTSNGIRITGFGHYLPERIVTNEEIRSRLKFPEMHPAEKAVIGNIGVNERRRANETETAMFMASKVAEMALKDAGK
KPEDVDLYILANWTDRYYLPDLAPQASKLSGTSNALAFDVSTACTGFVHGVQTASAYLGTNKFKNALVIGSERFSVRTRM
GGYGEFTAGDAAAGVFLEYTGDKNFGIIDSFLQDDGDLSGIIVTGPPPTSYVKSYPELVSKAADLTLKSMDLLLEKNGLT
IDDVDWVVPHPGTDVVVQDVLKRTKFPREKILMNFERVGNTSAASIPIVLSEYYYKGKFKKGDLFLTPAVGGGFYWGGLL
FRL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=28.9719626168224, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35496; Mature: 35365

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKNQTSNGIRITGFGHYLPERIVTNEEIRSRLKFPEMHPAEKAVIGNIGVNERRRANE
CCCCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHCCCCCCCCCCHHEEECCCCCCCCCCCH
TETAMFMASKVAEMALKDAGKKPEDVDLYILANWTDRYYLPDLAPQASKLSGTSNALAFD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEECCCCCCCHHHCCCCCCEEEEE
VSTACTGFVHGVQTASAYLGTNKFKNALVIGSERFSVRTRMGGYGEFTAGDAAAGVFLEY
HHHHHHHHHHHHHHHHHHHCCHHCCCEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEE
TGDKNFGIIDSFLQDDGDLSGIIVTGPPPTSYVKSYPELVSKAADLTLKSMDLLLEKNGL
CCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TIDDVDWVVPHPGTDVVVQDVLKRTKFPREKILMNFERVGNTSAASIPIVLSEYYYKGKF
EEECCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECHHHCCCC
KKGDLFLTPAVGGGFYWGGLLFRL
CCCCEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SGKNQTSNGIRITGFGHYLPERIVTNEEIRSRLKFPEMHPAEKAVIGNIGVNERRRANE
CCCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHCCCCCCCCCCHHEEECCCCCCCCCCCH
TETAMFMASKVAEMALKDAGKKPEDVDLYILANWTDRYYLPDLAPQASKLSGTSNALAFD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEECCCCCCCHHHCCCCCCEEEEE
VSTACTGFVHGVQTASAYLGTNKFKNALVIGSERFSVRTRMGGYGEFTAGDAAAGVFLEY
HHHHHHHHHHHHHHHHHHHCCHHCCCEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEE
TGDKNFGIIDSFLQDDGDLSGIIVTGPPPTSYVKSYPELVSKAADLTLKSMDLLLEKNGL
CCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TIDDVDWVVPHPGTDVVVQDVLKRTKFPREKILMNFERVGNTSAASIPIVLSEYYYKGKF
EEECCCEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECHHHCCCC
KKGDLFLTPAVGGGFYWGGLLFRL
CCCCEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA