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The map label for this gene is 116328783

Identifier: 116328783

GI number: 116328783

Start: 2534412

End: 2536469

Strand: Reverse

Name: 116328783

Synonym: LBL_2158

Alternate gene names: NA

Gene position: 2536469-2534412 (Counterclockwise)

Preceding gene: 116328784

Following gene: 116328782

Centisome position: 70.18

GC content: 40.62

Gene sequence:

>2058_bases
ATGAGAAAGATTCTAATAATTCTGGTCGGTTTCTTTTTATTAGGAACCTTAGGAAATCTTTATGCACGTCGAGGGAGAGT
AATTGAAAATCCGATCGACATTGTTGATGTGCCCTATCAAAATCAGGTTTCTAGTCCACCTGTGGAGTCCTTTTATCGGG
CTGATATGTTGGATCCGGAGCAGCTTAGAGGTTCGGATGGATTTTGGTCGGCTGGAATGTCGACAGCTCCCGGTAATTCG
GATCGTTCCCTTTTCAATCATGTTACTCTTGGCGCTCATACCGGGCGTTCTGCATATATTAGCGCGACCAGAACTCTGAG
CGACGCTCATATTTTCGGGAATTCGAATATCCCTCAGGATTATTACATTTATCAAATTGCGGGGGCGCCTAATATTTTTG
ATGTACAAAGATCGCTTGGGCCTTACACTCCGCCTCATGCGAGAGGAGACGTTGTGGCGTTGTTTCGAATTACATGGGGC
CAAGTTTATGGCTGGTACCATGTTAGCTTTGGCGTTCGAGGAGAATTTGTACCCAATTCTATGTTTGATAGAGGAAGGTA
TGGCAATACCACGTCTTCTCCGGGATATCCGGAATTAGCCGGGTTCCCTCAAGGTGATCCGCGGTGGGGAAACCGATTTT
TTGCGAACATTGCGAGGTGTGACGATTTTTTACGCTCAAATACTGGAAGGTGTTATTTAAGGGAGGATAAGCGCGATGCC
GACCAGAAAATTTACGATAAGAGTTACAAGAAAAGCAGGCTACCGAGTCTTCCTATATTTAAAACTCCTATTTCCAAAAC
TGCGTCCAGTAAAGGAATATATATAAGTTTATCCGGCTATCTATCCGGCCTTTGTTATGTTAGTTCAAAAACTAAAATTG
AATGCAGATCTATATTGAATAATGGAAAACTTAGCTCGGTTAAAGAAACCGTTATAAACGATACGGGTTATGAAGATTCT
TATATGTTTGGTGATGTCAATAATGATCAGAAGAACGATTTTTGTCGTTTAGTGGCGGGGAAGAATAACCTTACTTTATT
AAAGTGTAATCTTGGAGATGGTAATGGAAAATTTCCTAATGAGGTAAATTTCGGGGCTTTGGACGGTGGCTGGGCGTCAC
GAGGAGCCGCAGATAAGCGTGTGATTGTGAAAGGTATTTTTGGAAAAGCTTATTTTTGCCGTATTGTAAATGGGTATGAG
ATAGCTTGTACAGAGTTAGTTCGAAGAAATGATGGTAGAGGTCTTGTCACCTTTACTCAGGGAAAAACTAGAAAAACTAA
TGGATCCTATTATTATTCCACTTTGGTTAGGCAAGAGGGTATTTTTACGGATAGTAACCAAGACGGTATTCCTGACTGGT
GCAAAGTCAGTTATAACGCAGCGGATTTTGAAATTCGTTTCGAATGTTGGTGGTCGGAGAATGGAAATCAATTTTCTAAA
AAGGCAATCTTTACAAAGGTTATGGAAGCTAAGGGTGTGGTTGCTGCCGCAAATATTATGAATTCTAGGATATCGGATCT
TTGTTTTATTCCTGAATATCGGCAGAACAGTTCTGTTGCATGTTATGATTTTCCGAACGAGCTTTTATATCGCTCATCTC
CTCAATTCAATTATGCAACTCGATTTATCGAAGCCAAAAACCTTATGAGTAAAAATGACAATGCTCTTTGTGCTACCGAG
GTAATGAGTAAAAGTAAAATAATGAGACTTTCCTGCGTTTCAAAATATTCCAAGTCTTCTACCGGATTTTCTTCCGTTTT
TTCTACGTCGAACTTTGAAGATTACGGGAATGTTTTTAATAAGAAGCAGACAACAATTGTTTATTCTAACGGAAGAAGTT
TATTTTGTTCGATTCGACAAGATACTGCCGGGTGTGTACCACTCAATCAAAATGCTCCCAGTTGCCAACTGATAGCGCCG
GTTCAGATGCGGTTTGCGAGGCCTCTGAGGATCGGTCTGGGGTTGGAAAACTTTCAAGGGAAAAATGAATGTTTGGAATT
AAATACCAAAGAAGGGTGTTATAGGGAGGACGGAATTTGTTATAAATGGGATTATTGA

Upstream 100 bases:

>100_bases
CCAAATATAAATTGGTTTTAATCTTTCTTTGATAGCATTCCTTAATCAAGATATTTATCCATTTTAATGAGAAATGAAAA
GAGAGACAAAGGTGAAAATT

Downstream 100 bases:

>100_bases
TAATTGTTTTGCGGTGACACTTTAGATATTTTAGTAATTTATGAAATATTAATAAATTTAGGGCGTCGGTCTTGATTGCG
TGAATGTGCTGCCGACGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: LT-IIB [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MRKILIILVGFFLLGTLGNLYARRGRVIENPIDIVDVPYQNQVSSPPVESFYRADMLDPEQLRGSDGFWSAGMSTAPGNS
DRSLFNHVTLGAHTGRSAYISATRTLSDAHIFGNSNIPQDYYIYQIAGAPNIFDVQRSLGPYTPPHARGDVVALFRITWG
QVYGWYHVSFGVRGEFVPNSMFDRGRYGNTTSSPGYPELAGFPQGDPRWGNRFFANIARCDDFLRSNTGRCYLREDKRDA
DQKIYDKSYKKSRLPSLPIFKTPISKTASSKGIYISLSGYLSGLCYVSSKTKIECRSILNNGKLSSVKETVINDTGYEDS
YMFGDVNNDQKNDFCRLVAGKNNLTLLKCNLGDGNGKFPNEVNFGALDGGWASRGAADKRVIVKGIFGKAYFCRIVNGYE
IACTELVRRNDGRGLVTFTQGKTRKTNGSYYYSTLVRQEGIFTDSNQDGIPDWCKVSYNAADFEIRFECWWSENGNQFSK
KAIFTKVMEAKGVVAAANIMNSRISDLCFIPEYRQNSSVACYDFPNELLYRSSPQFNYATRFIEAKNLMSKNDNALCATE
VMSKSKIMRLSCVSKYSKSSTGFSSVFSTSNFEDYGNVFNKKQTTIVYSNGRSLFCSIRQDTAGCVPLNQNAPSCQLIAP
VQMRFARPLRIGLGLENFQGKNECLELNTKEGCYREDGICYKWDY

Sequences:

>Translated_685_residues
MRKILIILVGFFLLGTLGNLYARRGRVIENPIDIVDVPYQNQVSSPPVESFYRADMLDPEQLRGSDGFWSAGMSTAPGNS
DRSLFNHVTLGAHTGRSAYISATRTLSDAHIFGNSNIPQDYYIYQIAGAPNIFDVQRSLGPYTPPHARGDVVALFRITWG
QVYGWYHVSFGVRGEFVPNSMFDRGRYGNTTSSPGYPELAGFPQGDPRWGNRFFANIARCDDFLRSNTGRCYLREDKRDA
DQKIYDKSYKKSRLPSLPIFKTPISKTASSKGIYISLSGYLSGLCYVSSKTKIECRSILNNGKLSSVKETVINDTGYEDS
YMFGDVNNDQKNDFCRLVAGKNNLTLLKCNLGDGNGKFPNEVNFGALDGGWASRGAADKRVIVKGIFGKAYFCRIVNGYE
IACTELVRRNDGRGLVTFTQGKTRKTNGSYYYSTLVRQEGIFTDSNQDGIPDWCKVSYNAADFEIRFECWWSENGNQFSK
KAIFTKVMEAKGVVAAANIMNSRISDLCFIPEYRQNSSVACYDFPNELLYRSSPQFNYATRFIEAKNLMSKNDNALCATE
VMSKSKIMRLSCVSKYSKSSTGFSSVFSTSNFEDYGNVFNKKQTTIVYSNGRSLFCSIRQDTAGCVPLNQNAPSCQLIAP
VQMRFARPLRIGLGLENFQGKNECLELNTKEGCYREDGICYKWDY
>Mature_685_residues
MRKILIILVGFFLLGTLGNLYARRGRVIENPIDIVDVPYQNQVSSPPVESFYRADMLDPEQLRGSDGFWSAGMSTAPGNS
DRSLFNHVTLGAHTGRSAYISATRTLSDAHIFGNSNIPQDYYIYQIAGAPNIFDVQRSLGPYTPPHARGDVVALFRITWG
QVYGWYHVSFGVRGEFVPNSMFDRGRYGNTTSSPGYPELAGFPQGDPRWGNRFFANIARCDDFLRSNTGRCYLREDKRDA
DQKIYDKSYKKSRLPSLPIFKTPISKTASSKGIYISLSGYLSGLCYVSSKTKIECRSILNNGKLSSVKETVINDTGYEDS
YMFGDVNNDQKNDFCRLVAGKNNLTLLKCNLGDGNGKFPNEVNFGALDGGWASRGAADKRVIVKGIFGKAYFCRIVNGYE
IACTELVRRNDGRGLVTFTQGKTRKTNGSYYYSTLVRQEGIFTDSNQDGIPDWCKVSYNAADFEIRFECWWSENGNQFSK
KAIFTKVMEAKGVVAAANIMNSRISDLCFIPEYRQNSSVACYDFPNELLYRSSPQFNYATRFIEAKNLMSKNDNALCATE
VMSKSKIMRLSCVSKYSKSSTGFSSVFSTSNFEDYGNVFNKKQTTIVYSNGRSLFCSIRQDTAGCVPLNQNAPSCQLIAP
VQMRFARPLRIGLGLENFQGKNECLELNTKEGCYREDGICYKWDY

Specific function: The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001144 [H]

Pfam domain/function: PF01375 Enterotoxin_a [H]

EC number: NA

Molecular weight: Translated: 76831; Mature: 76831

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILIILVGFFLLGTLGNLYARRGRVIENPIDIVDVPYQNQVSSPPVESFYRADMLDPE
CCEEHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEECCCCCCCCCCCHHHHHHHCCCCHH
QLRGSDGFWSAGMSTAPGNSDRSLFNHVTLGAHTGRSAYISATRTLSDAHIFGNSNIPQD
HHCCCCCCCCCCCCCCCCCCCHHHHHEEEECCCCCCCEEEEEEEEECCEEEECCCCCCCC
YYIYQIAGAPNIFDVQRSLGPYTPPHARGDVVALFRITWGQVYGWYHVSFGVRGEFVPNS
EEEEEECCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEEECCEEEEEEEEECCCCCCCCCH
MFDRGRYGNTTSSPGYPELAGFPQGDPRWGNRFFANIARCDDFLRSNTGRCYLREDKRDA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
DQKIYDKSYKKSRLPSLPIFKTPISKTASSKGIYISLSGYLSGLCYVSSKTKIECRSILN
HHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEEHHHCEEEEECCCCCHHHHHHHC
NGKLSSVKETVINDTGYEDSYMFGDVNNDQKNDFCRLVAGKNNLTLLKCNLGDGNGKFPN
CCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCC
EVNFGALDGGWASRGAADKRVIVKGIFGKAYFCRIVNGYEIACTELVRRNDGRGLVTFTQ
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECC
GKTRKTNGSYYYSTLVRQEGIFTDSNQDGIPDWCKVSYNAADFEIRFECWWSENGNQFSK
CCCCCCCCCEEEEEHHHHCCCEECCCCCCCCHHHEEECCCCCEEEEEEEEECCCCCCHHH
KAIFTKVMEAKGVVAAANIMNSRISDLCFIPEYRQNSSVACYDFPNELLYRSSPQFNYAT
HHHHHHHHHHCCCEEHHHHHHHHHHHEEECCCCCCCCCEEEEECCHHHHHCCCCCCCHHH
RFIEAKNLMSKNDNALCATEVMSKSKIMRLSCVSKYSKSSTGFSSVFSTSNFEDYGNVFN
HHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHCC
KKQTTIVYSNGRSLFCSIRQDTAGCVPLNQNAPSCQLIAPVQMRFARPLRIGLGLENFQG
CCCEEEEEECCCEEEEEEECCCCCCEECCCCCCCCEEECHHHHHHCCCEEEECCCCCCCC
KNECLELNTKEGCYREDGICYKWDY
CCCEEEECCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MRKILIILVGFFLLGTLGNLYARRGRVIENPIDIVDVPYQNQVSSPPVESFYRADMLDPE
CCEEHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEECCCCCCCCCCCHHHHHHHCCCCHH
QLRGSDGFWSAGMSTAPGNSDRSLFNHVTLGAHTGRSAYISATRTLSDAHIFGNSNIPQD
HHCCCCCCCCCCCCCCCCCCCHHHHHEEEECCCCCCCEEEEEEEEECCEEEECCCCCCCC
YYIYQIAGAPNIFDVQRSLGPYTPPHARGDVVALFRITWGQVYGWYHVSFGVRGEFVPNS
EEEEEECCCCCHHHHHHHCCCCCCCCCCCCEEEEEEEEECCEEEEEEEEECCCCCCCCCH
MFDRGRYGNTTSSPGYPELAGFPQGDPRWGNRFFANIARCDDFLRSNTGRCYLREDKRDA
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
DQKIYDKSYKKSRLPSLPIFKTPISKTASSKGIYISLSGYLSGLCYVSSKTKIECRSILN
HHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEEHHHCEEEEECCCCCHHHHHHHC
NGKLSSVKETVINDTGYEDSYMFGDVNNDQKNDFCRLVAGKNNLTLLKCNLGDGNGKFPN
CCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCC
EVNFGALDGGWASRGAADKRVIVKGIFGKAYFCRIVNGYEIACTELVRRNDGRGLVTFTQ
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECC
GKTRKTNGSYYYSTLVRQEGIFTDSNQDGIPDWCKVSYNAADFEIRFECWWSENGNQFSK
CCCCCCCCCEEEEEHHHHCCCEECCCCCCCCHHHEEECCCCCEEEEEEEEECCCCCCHHH
KAIFTKVMEAKGVVAAANIMNSRISDLCFIPEYRQNSSVACYDFPNELLYRSSPQFNYAT
HHHHHHHHHHCCCEEHHHHHHHHHHHEEECCCCCCCCCEEEEECCHHHHHCCCCCCCHHH
RFIEAKNLMSKNDNALCATEVMSKSKIMRLSCVSKYSKSSTGFSSVFSTSNFEDYGNVFN
HHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHCC
KKQTTIVYSNGRSLFCSIRQDTAGCVPLNQNAPSCQLIAPVQMRFARPLRIGLGLENFQG
CCCEEEEEECCCEEEEEEECCCCCCEECCCCCCCCEEECHHHHHHCCCEEEECCCCCCCC
KNECLELNTKEGCYREDGICYKWDY
CCCEEEECCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670900; 8805549 [H]