| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is mrcA [H]
Identifier: 116328749
GI number: 116328749
Start: 2485200
End: 2487638
Strand: Reverse
Name: mrcA [H]
Synonym: LBL_2123
Alternate gene names: 116328749
Gene position: 2487638-2485200 (Counterclockwise)
Preceding gene: 116328750
Following gene: 116328748
Centisome position: 68.82
GC content: 47.03
Gene sequence:
>2439_bases ATGAAAAGTATCGGACTTCATAGAACTTCCAAAGCCTTGCTCGTCATCGCTCTTTTAGGAGGATTTTTTTTCGGTTATAT TCTTTCGGAAGTGGACGAAGGGGGAGAACTTGCGATGCTTGCCTCTTACCAACCTACGACTCCGACCAGACTCTACGACA TCAACGGAGCTGTGTTTGCCGAGCTTTACAAACACAAACAGCAACTTCTGAAATACCAAGACATTCCTCCTCATGTGGTA CAGGCGTTTCTATCCGTGGAGGACAACAACTTCTTCAATCACTTCGGGATCGACTTTATGGCGATTCTCCGCGCCGGGAT CGTAAACGTAATTTCGGGAAGAATCAAACAAGGCGGTTCTACTCTGACTCAGCAACTCGCCAAAACAGTTTTGCAAAATA GAAAACGTTCCTTCGCGAGAAAGTTCATCGAGGCGCTGTTTACTCTTCAGATAGAACAAGAATATTCAAAAGAAGAGATA TTAGAAATTTATTTTAATCTGATTTATCTCGGGCATGGAACCACGGGGCTTGCCTCCGCAGCGGACGTATACTTTCAAAA GGACGTGAGCGATCTGGATGTGGCCGAGGCCGCTCTGCTCGCAAGACTTCCCAAAGCCCCCGTAAAATATTCTCCATTCA AAAACCCCAAAATTTCGAAAGGCGCTCATCTGAGTGTTCTGAGGCTCATGGCGGACCAGGGTTATATTCCAACCGATAGG ATTCAGTCGATTCACGACGATTTCTGGAATAAATATTGGCCGGTCGTCATCACACAGTCTCCTTCCCAATCCACTTGGGG AAACCGTTTGAACAAAGCGCCTCATTTTACCGAATACGTTCGCCAGAAACTTGAAAAGGAGCTTGGAGAAGATAAGGTTT ATACCGGAGGCTTAAAAGTTTATACGACTCTCGACGCTCGTAAACAAGAGATCGCACAGGAGGAATTGTCCAAGGCGATC AAAAAACACGACGATCTCGTTTCCGGAGTAACCGTAAATTATTCGGGAGGTGCGGATCGCGGACTTGTAGGTCTTTATTA TCTTATGGGTTCCGTCTTCCCCGTGGGAATGCCTTTTATCAGTAAACTCGACGATAAGGCGAACTACCGGGTTGCGTTGG AAAGAGAATTGATCGATGCGGCCGATATCCTTGCGATCTTAACCCCGGGTGAAAACGAGTCTTCGGCGATTTCCGAATTT CAAAAACAAACCGCGGTCTTCGGAAAAAATCTTCACGTAGAAGGGGCGGCGATTACGATCGAACCTTCCACCGGTTATAT CCAAACCATGGTGGGCGGTTACGAATTCACGCCGAAAAATCAGTTCAACCGAGCCACAATGGCGAGACGTCAAACGGGTT CCGCGTTCAAACCGTTTGTCTACGGGGCAGCGATTCAAGAAAGGGTCGTAGGGAGCGGAACTGGGATTATGGACGCACCT CTCACGACTCTTACGGAAGAGGGGGAAGGTTGGTCACCTCAGGATTTCGACGGAGACTTCCTCGGAATGGTTCCACTTTC CAGAGCTTTATCCTTATCTTTAAATATTGTATCGGTTCAAGTGTTTTTGCGGACTGGACCCGACGCGGTCATCGATTTTT CTTCCAGACTTTTAGGAGTCAATCCGACTCGCTTTCCACCAAGCCCGGCTCTTGCGCTTGGGATTGCGGAACTCACACCA CTTGAGATGGCGCTCGGTTACGCGACTATCGCCAACAATGGAAGAAGGGTGATTCCGTTTTCCGTTCGTTATGTGATCGA TCAAAGTGGGAACGTAGTTTATAACGAAGAGACCAAGGTTCAGGAAGAATTACAGAGACAGGCTAAAGATGGAAGTATCC AAGTGATCTCCGAAGGAACCGCCTACATTCTGAAAAAAATGCTGACCAATGTGGCGATGGCTGGAACCGCCGCGATGGGG TTAAGAGATCCCGAGAAAGGAAATTACAGAGGAATCGCCGCCGGAAAAACCGGATCGACTTCTTCTTTTACAAACGCATG GTACTGTGGATTCGATCCGAATTATACGACTGTTATTTGGTTGGGATTCGATAAAAGTTCGATTTCTTTGGGAAGAGGGC AAGCCGCTTCCGTGCTTGCGGTTCCGATTTGGGGAAGAATGTACAATCGTTTTTACGGAGGTCAAAATTATCCTACCTTC GGCGAAGACATTATACCCAAAGAAGTACAAGGCGGGGGCACTTGTGCTTACAATGGACTTTCTCCAAAACCGGGAGTATG TCCCGTAACTCAGAATTTGACACTCAAACCAATAACTGTAGCCGGAGTGACCAAAGCTGTGATGGGTAATCGCCAGTGCG ATGGGGAAAGGGATCATCACAAGTCTGTGGATTTTAGAGAATTCTTACAGAAAGAATATCAGATTAGCGACGAGGAATTG GGTAAAATGGATCGAAAGTTCAAACCTAGGACGGAATAA
Upstream 100 bases:
>100_bases TGGATATCATTCTTGAGGAAGCTCGGGCGCACGCGGTGTCGCTCGGCAACTCGTCTATTCGGGTCGAACTTGCCGTAGAA GGAAACGTATATAAACTATC
Downstream 100 bases:
>100_bases TTGTGTTTTAGAGAATTTCGTTTACAGAATTTTTTCATTTAGAAGGATTGAAACCGAGACTTACGCTTTTTTGTATCTTA AGCCTCTTGAAAGGAATCAT
Product: membrane carboxypeptidase/penicillin-binding protein 1
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 812; Mature: 812
Protein sequence:
>812_residues MKSIGLHRTSKALLVIALLGGFFFGYILSEVDEGGELAMLASYQPTTPTRLYDINGAVFAELYKHKQQLLKYQDIPPHVV QAFLSVEDNNFFNHFGIDFMAILRAGIVNVISGRIKQGGSTLTQQLAKTVLQNRKRSFARKFIEALFTLQIEQEYSKEEI LEIYFNLIYLGHGTTGLASAADVYFQKDVSDLDVAEAALLARLPKAPVKYSPFKNPKISKGAHLSVLRLMADQGYIPTDR IQSIHDDFWNKYWPVVITQSPSQSTWGNRLNKAPHFTEYVRQKLEKELGEDKVYTGGLKVYTTLDARKQEIAQEELSKAI KKHDDLVSGVTVNYSGGADRGLVGLYYLMGSVFPVGMPFISKLDDKANYRVALERELIDAADILAILTPGENESSAISEF QKQTAVFGKNLHVEGAAITIEPSTGYIQTMVGGYEFTPKNQFNRATMARRQTGSAFKPFVYGAAIQERVVGSGTGIMDAP LTTLTEEGEGWSPQDFDGDFLGMVPLSRALSLSLNIVSVQVFLRTGPDAVIDFSSRLLGVNPTRFPPSPALALGIAELTP LEMALGYATIANNGRRVIPFSVRYVIDQSGNVVYNEETKVQEELQRQAKDGSIQVISEGTAYILKKMLTNVAMAGTAAMG LRDPEKGNYRGIAAGKTGSTSSFTNAWYCGFDPNYTTVIWLGFDKSSISLGRGQAASVLAVPIWGRMYNRFYGGQNYPTF GEDIIPKEVQGGGTCAYNGLSPKPGVCPVTQNLTLKPITVAGVTKAVMGNRQCDGERDHHKSVDFREFLQKEYQISDEEL GKMDRKFKPRTE
Sequences:
>Translated_812_residues MKSIGLHRTSKALLVIALLGGFFFGYILSEVDEGGELAMLASYQPTTPTRLYDINGAVFAELYKHKQQLLKYQDIPPHVV QAFLSVEDNNFFNHFGIDFMAILRAGIVNVISGRIKQGGSTLTQQLAKTVLQNRKRSFARKFIEALFTLQIEQEYSKEEI LEIYFNLIYLGHGTTGLASAADVYFQKDVSDLDVAEAALLARLPKAPVKYSPFKNPKISKGAHLSVLRLMADQGYIPTDR IQSIHDDFWNKYWPVVITQSPSQSTWGNRLNKAPHFTEYVRQKLEKELGEDKVYTGGLKVYTTLDARKQEIAQEELSKAI KKHDDLVSGVTVNYSGGADRGLVGLYYLMGSVFPVGMPFISKLDDKANYRVALERELIDAADILAILTPGENESSAISEF QKQTAVFGKNLHVEGAAITIEPSTGYIQTMVGGYEFTPKNQFNRATMARRQTGSAFKPFVYGAAIQERVVGSGTGIMDAP LTTLTEEGEGWSPQDFDGDFLGMVPLSRALSLSLNIVSVQVFLRTGPDAVIDFSSRLLGVNPTRFPPSPALALGIAELTP LEMALGYATIANNGRRVIPFSVRYVIDQSGNVVYNEETKVQEELQRQAKDGSIQVISEGTAYILKKMLTNVAMAGTAAMG LRDPEKGNYRGIAAGKTGSTSSFTNAWYCGFDPNYTTVIWLGFDKSSISLGRGQAASVLAVPIWGRMYNRFYGGQNYPTF GEDIIPKEVQGGGTCAYNGLSPKPGVCPVTQNLTLKPITVAGVTKAVMGNRQCDGERDHHKSVDFREFLQKEYQISDEEL GKMDRKFKPRTE >Mature_812_residues MKSIGLHRTSKALLVIALLGGFFFGYILSEVDEGGELAMLASYQPTTPTRLYDINGAVFAELYKHKQQLLKYQDIPPHVV QAFLSVEDNNFFNHFGIDFMAILRAGIVNVISGRIKQGGSTLTQQLAKTVLQNRKRSFARKFIEALFTLQIEQEYSKEEI LEIYFNLIYLGHGTTGLASAADVYFQKDVSDLDVAEAALLARLPKAPVKYSPFKNPKISKGAHLSVLRLMADQGYIPTDR IQSIHDDFWNKYWPVVITQSPSQSTWGNRLNKAPHFTEYVRQKLEKELGEDKVYTGGLKVYTTLDARKQEIAQEELSKAI KKHDDLVSGVTVNYSGGADRGLVGLYYLMGSVFPVGMPFISKLDDKANYRVALERELIDAADILAILTPGENESSAISEF QKQTAVFGKNLHVEGAAITIEPSTGYIQTMVGGYEFTPKNQFNRATMARRQTGSAFKPFVYGAAIQERVVGSGTGIMDAP LTTLTEEGEGWSPQDFDGDFLGMVPLSRALSLSLNIVSVQVFLRTGPDAVIDFSSRLLGVNPTRFPPSPALALGIAELTP LEMALGYATIANNGRRVIPFSVRYVIDQSGNVVYNEETKVQEELQRQAKDGSIQVISEGTAYILKKMLTNVAMAGTAAMG LRDPEKGNYRGIAAGKTGSTSSFTNAWYCGFDPNYTTVIWLGFDKSSISLGRGQAASVLAVPIWGRMYNRFYGGQNYPTF GEDIIPKEVQGGGTCAYNGLSPKPGVCPVTQNLTLKPITVAGVTKAVMGNRQCDGERDHHKSVDFREFLQKEYQISDEEL GKMDRKFKPRTE
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=825, Percent_Identity=27.2727272727273, Blast_Score=265, Evalue=8e-72, Organism=Escherichia coli, GI1786343, Length=281, Percent_Identity=31.6725978647687, Blast_Score=124, Evalue=2e-29, Organism=Escherichia coli, GI1788867, Length=276, Percent_Identity=29.7101449275362, Blast_Score=113, Evalue=5e-26, Organism=Escherichia coli, GI1789601, Length=164, Percent_Identity=34.7560975609756, Blast_Score=88, Evalue=2e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 3.4.-.-; 2.4.2.-
Molecular weight: Translated: 89577; Mature: 89577
Theoretical pI: Translated: 7.67; Mature: 7.67
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKSIGLHRTSKALLVIALLGGFFFGYILSEVDEGGELAMLASYQPTTPTRLYDINGAVFA CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHH ELYKHKQQLLKYQDIPPHVVQAFLSVEDNNFFNHFGIDFMAILRAGIVNVISGRIKQGGS HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCH TLTQQLAKTVLQNRKRSFARKFIEALFTLQIEQEYSKEEILEIYFNLIYLGHGTTGLASA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCHHHH ADVYFQKDVSDLDVAEAALLARLPKAPVKYSPFKNPKISKGAHLSVLRLMADQGYIPTDR HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHH IQSIHDDFWNKYWPVVITQSPSQSTWGNRLNKAPHFTEYVRQKLEKELGEDKVYTGGLKV HHHHHHHHHCCCCCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCEEE YTTLDARKQEIAQEELSKAIKKHDDLVSGVTVNYSGGADRGLVGLYYLMGSVFPVGMPFI EEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHH SKLDDKANYRVALERELIDAADILAILTPGENESSAISEFQKQTAVFGKNLHVEGAAITI HHCCCCCCEEEEEHHHHHCHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEECCEEEEE EPSTGYIQTMVGGYEFTPKNQFNRATMARRQTGSAFKPFVYGAAIQERVVGSGTGIMDAP ECCCCCHHHHHCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC LTTLTEEGEGWSPQDFDGDFLGMVPLSRALSLSLNIVSVQVFLRTGPDAVIDFSSRLLGV HHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHEEEEEEEEEEEEECCCCCEEECCCCEECC NPTRFPPSPALALGIAELTPLEMALGYATIANNGRRVIPFSVRYVIDQSGNVVYNEETKV CCCCCCCCCHHHHHHHHCCHHHHHHHHHEECCCCCEEEEEEEEEEEECCCCEEECCHHHH QEELQRQAKDGSIQVISEGTAYILKKMLTNVAMAGTAAMGLRDPEKGNYRGIAAGKTGST HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC SSFTNAWYCGFDPNYTTVIWLGFDKSSISLGRGQAASVLAVPIWGRMYNRFYGGQNYPTF CCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCC GEDIIPKEVQGGGTCAYNGLSPKPGVCPVTQNLTLKPITVAGVTKAVMGNRQCDGERDHH CCCCCCHHCCCCCCEEECCCCCCCCCCCCCCCCEECEEEHHHHHHHHHCCCCCCCCCCCC KSVDFREFLQKEYQISDEELGKMDRKFKPRTE CCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCC >Mature Secondary Structure MKSIGLHRTSKALLVIALLGGFFFGYILSEVDEGGELAMLASYQPTTPTRLYDINGAVFA CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHH ELYKHKQQLLKYQDIPPHVVQAFLSVEDNNFFNHFGIDFMAILRAGIVNVISGRIKQGGS HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCH TLTQQLAKTVLQNRKRSFARKFIEALFTLQIEQEYSKEEILEIYFNLIYLGHGTTGLASA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCHHHH ADVYFQKDVSDLDVAEAALLARLPKAPVKYSPFKNPKISKGAHLSVLRLMADQGYIPTDR HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHH IQSIHDDFWNKYWPVVITQSPSQSTWGNRLNKAPHFTEYVRQKLEKELGEDKVYTGGLKV HHHHHHHHHCCCCCEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCEEE YTTLDARKQEIAQEELSKAIKKHDDLVSGVTVNYSGGADRGLVGLYYLMGSVFPVGMPFI EEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHH SKLDDKANYRVALERELIDAADILAILTPGENESSAISEFQKQTAVFGKNLHVEGAAITI HHCCCCCCEEEEEHHHHHCHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEECCEEEEE EPSTGYIQTMVGGYEFTPKNQFNRATMARRQTGSAFKPFVYGAAIQERVVGSGTGIMDAP ECCCCCHHHHHCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCC LTTLTEEGEGWSPQDFDGDFLGMVPLSRALSLSLNIVSVQVFLRTGPDAVIDFSSRLLGV HHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHEEEEEEEEEEEEECCCCCEEECCCCEECC NPTRFPPSPALALGIAELTPLEMALGYATIANNGRRVIPFSVRYVIDQSGNVVYNEETKV CCCCCCCCCHHHHHHHHCCHHHHHHHHHEECCCCCEEEEEEEEEEEECCCCEEECCHHHH QEELQRQAKDGSIQVISEGTAYILKKMLTNVAMAGTAAMGLRDPEKGNYRGIAAGKTGST HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC SSFTNAWYCGFDPNYTTVIWLGFDKSSISLGRGQAASVLAVPIWGRMYNRFYGGQNYPTF CCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCC GEDIIPKEVQGGGTCAYNGLSPKPGVCPVTQNLTLKPITVAGVTKAVMGNRQCDGERDHH CCCCCCHHCCCCCCEEECCCCCCCCCCCCCCCCEECEEEHHHHHHHHHCCCCCCCCCCCC KSVDFREFLQKEYQISDEELGKMDRKFKPRTE CCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA