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The map label for this gene is hppA [H]

Identifier: 116328688

GI number: 116328688

Start: 2413106

End: 2415223

Strand: Reverse

Name: hppA [H]

Synonym: LBL_2060

Alternate gene names: 116328688

Gene position: 2415223-2413106 (Counterclockwise)

Preceding gene: 116328695

Following gene: 116328685

Centisome position: 66.82

GC content: 48.44

Gene sequence:

>2118_bases
ATGAATTCAGTTACGATTATTATCGCCATGTCTATTTTGGCGATCGTCACTGCGGTAGTTTATGCCCTGAAAGTTACCAC
CATCAAAGTGGGAGCTGCGGGCGGTAACGAGAAAGAAACGAAAAAACTTTTAGAAATATCATCCGCCATTTCCGAAGGGG
CTATGGCTTTCCTCCTTCGGGAATACAAGGTCATTTCCGTATTCATCGCCTTTATGGCCGTCTTGATTGTTCTTCTTTTG
GACAATCCTGCCACCGAAGGGTTCAATGATGGACTTCATACGGCGATTGCGTTTATCGCAGGGGCTATCATCTCTTGCCT
TTCCGGTTTTATCGGAATGAAAATCGCAACCGCAGGAAATGTAAGAACGGCGGAGGCGGCAAAAACTTCCCTATCCAAAG
CTTTCCGAGTCGCTTTTGACTCCGGAGCGGTGATGGGATTCGGACTCGTGGGATTGGCGATCCTCGGGATGATTATTCTC
TTTCTTCTTTTTACGGGAATGTATCCTACGATAGAAAAACACTTTCTCATGGAATCTCTGGCCGGTTTCGGTCTGGGCGG
TTCCGCTGTGGCGCTTTTCGGTCGCGTAGGCGGCGGGATTTATACAAAAGCCGCGGATGTGGGAGCGGACTTAGTCGGTA
AGGTGGAAAAGGGAATTCCGGAAGATGATCCAAGAAACCCCGCAACGATTGCGGATAACGTGGGAGACAACGTGGGGGAC
GTAGCCGGAATGGGAGCCGACCTATTCGGTTCTTGTGCGGAAGCGACTTGTGCGGCTCTTGTGATCGGCGCTACCGCGTC
GGCTCTCTCCGGATCCGTGGACGCTCTTTTATATCCTCTGTTGATTTCCGCGTTTGGAATTCCGGCTTCTCTTTTGACCA
GCTTTCTTGCAAGAGTCAAGGAAGGTGGAAACGTAGAATCCGCGTTGAAAGTTCAACTCTGGGTTTCCACCTTATTTGTC
GCGGGGATCATGTATTTCGTAACGAATACGTTTATGGTGGATTCTTTTGAAATCGCAGGGAAAACGATTACTAAGTGGGA
TGTTTATATATCCATGATCGTCGGGCTTTTTTCTGGAATGTTCATAGGGATCGTAACCGAGTATTATACTTCTCATTCTT
ACAAACCCGTTCGTGAAGTCGCAGAAGCGTCTAACACCGGAGCGGCGACGAACATCATCTACGGACTATCTCTCGGATAT
CATTCTTCCGTAATTCCGGTAATCCTTCTTGTAATTACCATCGTAACCGCGAACCTTCTTGCGGGAATGTATGGAATCGC
AATCGCGGCGCTCGGAATGATTTCCACGATTGCGATCGGACTAACGATCGACGCTTACGGTCCCGTTTCGGATAACGCGG
GCGGAATCGCGGAGATGGCGGAACTCGGAAAAGAAGTTCGCGATAGAACCGATACTCTTGACGCTGCCGGAAACACCACC
GCTGCGATCGGTAAGGGTTTTGCGATCGGATCCGCAGCGCTTACTTCTCTCGCACTTTTTGCGGCGTTTATTACGAGAAC
TCATACGACGAGCCTTGAAGTCCTGAACGCGGAAGTATTCGGCGGGTTGATGTTCGGAGCAATGCTTCCTTTTTTATTCA
CTGCTATGACAATGAAATCCGTAGGTAAGGCTGCGGTTGACATGGTGGAGGAAGTTCGTAAACAATTCCGTGAAATTCCG
GGAATTATGGAAGGAAAAAATAAACCGGATTACAAACGTTGTGTGGACATTTCCACGACGGCGGCGCTCAGGGAAATGAT
TCTTCCTGGATTACTTGTTCTTTTGACTCCAGTTTTGGTCGGGTATCTTTTCGGAGTGAAAACTCTTGCGGGGGTTCTCG
CGGGTGCGTTAGTAGCGGGAGTGGTTCTTGCTATTTCTGCGGCAAATTCCGGCGGAGGTTGGGACAACGCAAAGAAATAC
ATCGAAAAAAAAACCGGCGGTAAAGGTTCCGACCAGCACAAAGCGGCGGTTGTAGGTGATACCGTGGGAGATCCATTCAA
AGATACTTCCGGACCTTCCATCAACATTCTGATCAAATTGATGGCGATTACAAGTCTCGTTTTTGCGGAATTTTTCGTTC
AACAAGGCGGACTTTTGATGAGATTGTTTCATTATTAA

Upstream 100 bases:

>100_bases
GAACCAAGTGGATAGCAGTCTCCCAGCCAGTCTGTTCGGTAGAATTCTTCCCATCTTTTTAAACATCGGAACATTGAAAA
AAAACAAGAGGTTTCACTGA

Downstream 100 bases:

>100_bases
GAATTTTTAAATTAGTATTTCTTAAAATACCGGTTCTTTCGCGAAAGTGGGAGAGCCTTTTTTGTTTTATTCGAGAAAAT
CGGAGGACCTTTTTTTCGTG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MNSVTIIIAMSILAIVTAVVYALKVTTIKVGAAGGNEKETKKLLEISSAISEGAMAFLLREYKVISVFIAFMAVLIVLLL
DNPATEGFNDGLHTAIAFIAGAIISCLSGFIGMKIATAGNVRTAEAAKTSLSKAFRVAFDSGAVMGFGLVGLAILGMIIL
FLLFTGMYPTIEKHFLMESLAGFGLGGSAVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGD
VAGMGADLFGSCAEATCAALVIGATASALSGSVDALLYPLLISAFGIPASLLTSFLARVKEGGNVESALKVQLWVSTLFV
AGIMYFVTNTFMVDSFEIAGKTITKWDVYISMIVGLFSGMFIGIVTEYYTSHSYKPVREVAEASNTGAATNIIYGLSLGY
HSSVIPVILLVITIVTANLLAGMYGIAIAALGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTT
AAIGKGFAIGSAALTSLALFAAFITRTHTTSLEVLNAEVFGGLMFGAMLPFLFTAMTMKSVGKAAVDMVEEVRKQFREIP
GIMEGKNKPDYKRCVDISTTAALREMILPGLLVLLTPVLVGYLFGVKTLAGVLAGALVAGVVLAISAANSGGGWDNAKKY
IEKKTGGKGSDQHKAAVVGDTVGDPFKDTSGPSINILIKLMAITSLVFAEFFVQQGGLLMRLFHY

Sequences:

>Translated_705_residues
MNSVTIIIAMSILAIVTAVVYALKVTTIKVGAAGGNEKETKKLLEISSAISEGAMAFLLREYKVISVFIAFMAVLIVLLL
DNPATEGFNDGLHTAIAFIAGAIISCLSGFIGMKIATAGNVRTAEAAKTSLSKAFRVAFDSGAVMGFGLVGLAILGMIIL
FLLFTGMYPTIEKHFLMESLAGFGLGGSAVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGD
VAGMGADLFGSCAEATCAALVIGATASALSGSVDALLYPLLISAFGIPASLLTSFLARVKEGGNVESALKVQLWVSTLFV
AGIMYFVTNTFMVDSFEIAGKTITKWDVYISMIVGLFSGMFIGIVTEYYTSHSYKPVREVAEASNTGAATNIIYGLSLGY
HSSVIPVILLVITIVTANLLAGMYGIAIAALGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTT
AAIGKGFAIGSAALTSLALFAAFITRTHTTSLEVLNAEVFGGLMFGAMLPFLFTAMTMKSVGKAAVDMVEEVRKQFREIP
GIMEGKNKPDYKRCVDISTTAALREMILPGLLVLLTPVLVGYLFGVKTLAGVLAGALVAGVVLAISAANSGGGWDNAKKY
IEKKTGGKGSDQHKAAVVGDTVGDPFKDTSGPSINILIKLMAITSLVFAEFFVQQGGLLMRLFHY
>Mature_705_residues
MNSVTIIIAMSILAIVTAVVYALKVTTIKVGAAGGNEKETKKLLEISSAISEGAMAFLLREYKVISVFIAFMAVLIVLLL
DNPATEGFNDGLHTAIAFIAGAIISCLSGFIGMKIATAGNVRTAEAAKTSLSKAFRVAFDSGAVMGFGLVGLAILGMIIL
FLLFTGMYPTIEKHFLMESLAGFGLGGSAVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGD
VAGMGADLFGSCAEATCAALVIGATASALSGSVDALLYPLLISAFGIPASLLTSFLARVKEGGNVESALKVQLWVSTLFV
AGIMYFVTNTFMVDSFEIAGKTITKWDVYISMIVGLFSGMFIGIVTEYYTSHSYKPVREVAEASNTGAATNIIYGLSLGY
HSSVIPVILLVITIVTANLLAGMYGIAIAALGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTT
AAIGKGFAIGSAALTSLALFAAFITRTHTTSLEVLNAEVFGGLMFGAMLPFLFTAMTMKSVGKAAVDMVEEVRKQFREIP
GIMEGKNKPDYKRCVDISTTAALREMILPGLLVLLTPVLVGYLFGVKTLAGVLAGALVAGVVLAISAANSGGGWDNAKKY
IEKKTGGKGSDQHKAAVVGDTVGDPFKDTSGPSINILIKLMAITSLVFAEFFVQQGGLLMRLFHY

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 73326; Mature: 73326

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVTIIIAMSILAIVTAVVYALKVTTIKVGAAGGNEKETKKLLEISSAISEGAMAFLLR
CCCEEHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EYKVISVFIAFMAVLIVLLLDNPATEGFNDGLHTAIAFIAGAIISCLSGFIGMKIATAGN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEECCCC
VRTAEAAKTSLSKAFRVAFDSGAVMGFGLVGLAILGMIILFLLFTGMYPTIEKHFLMESL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AGFGLGGSAVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGD
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHH
VAGMGADLFGSCAEATCAALVIGATASALSGSVDALLYPLLISAFGIPASLLTSFLARVK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EGGNVESALKVQLWVSTLFVAGIMYFVTNTFMVDSFEIAGKTITKWDVYISMIVGLFSGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCCCHHHHHHHHHHHHHHHHHH
FIGIVTEYYTSHSYKPVREVAEASNTGAATNIIYGLSLGYHSSVIPVILLVITIVTANLL
HHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
AGMYGIAIAALGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTT
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
AAIGKGFAIGSAALTSLALFAAFITRTHTTSLEVLNAEVFGGLMFGAMLPFLFTAMTMKS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGKAAVDMVEEVRKQFREIPGIMEGKNKPDYKRCVDISTTAALREMILPGLLVLLTPVLV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
GYLFGVKTLAGVLAGALVAGVVLAISAANSGGGWDNAKKYIEKKTGGKGSDQHKAAVVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECC
TVGDPFKDTSGPSINILIKLMAITSLVFAEFFVQQGGLLMRLFHY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure
MNSVTIIIAMSILAIVTAVVYALKVTTIKVGAAGGNEKETKKLLEISSAISEGAMAFLLR
CCCEEHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EYKVISVFIAFMAVLIVLLLDNPATEGFNDGLHTAIAFIAGAIISCLSGFIGMKIATAGN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEECCCC
VRTAEAAKTSLSKAFRVAFDSGAVMGFGLVGLAILGMIILFLLFTGMYPTIEKHFLMESL
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AGFGLGGSAVALFGRVGGGIYTKAADVGADLVGKVEKGIPEDDPRNPATIADNVGDNVGD
HCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHH
VAGMGADLFGSCAEATCAALVIGATASALSGSVDALLYPLLISAFGIPASLLTSFLARVK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EGGNVESALKVQLWVSTLFVAGIMYFVTNTFMVDSFEIAGKTITKWDVYISMIVGLFSGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCCCHHHHHHHHHHHHHHHHHH
FIGIVTEYYTSHSYKPVREVAEASNTGAATNIIYGLSLGYHSSVIPVILLVITIVTANLL
HHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
AGMYGIAIAALGMISTIAIGLTIDAYGPVSDNAGGIAEMAELGKEVRDRTDTLDAAGNTT
HHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCH
AAIGKGFAIGSAALTSLALFAAFITRTHTTSLEVLNAEVFGGLMFGAMLPFLFTAMTMKS
HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGKAAVDMVEEVRKQFREIPGIMEGKNKPDYKRCVDISTTAALREMILPGLLVLLTPVLV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
GYLFGVKTLAGVLAGALVAGVVLAISAANSGGGWDNAKKYIEKKTGGKGSDQHKAAVVGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECC
TVGDPFKDTSGPSINILIKLMAITSLVFAEFFVQQGGLLMRLFHY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA