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The map label for this gene is lldD [H]

Identifier: 116328676

GI number: 116328676

Start: 2397695

End: 2399977

Strand: Reverse

Name: lldD [H]

Synonym: LBL_2046

Alternate gene names: 116328676

Gene position: 2399977-2397695 (Counterclockwise)

Preceding gene: 116328677

Following gene: 116328675

Centisome position: 66.4

GC content: 45.69

Gene sequence:

>2283_bases
TTGTCGCTGAGCCATAAAATCGCAGGAAAAACGATATTGATCGTGGGTGGGGGACTTCTACAAGTACCGATTATCCAAAC
CGCGAGAATGATGAAACTTACTACCGTAGTCGCCGATATGAACGGAGACGCTCCCGGAATGAGGATCTGTGATATTCCCA
TGGTAATGAGTACGAAGGATATCGAGGGAATGGTGCGAGAGTCTAAAAAGCTCGCGACGACAATCAAAATAGACGGAGTG
ATCACAGCGGGAACCGACGCGAGTATGACGGTGGCTGCGGTTGCAAATGCACTTGATCTTCCGGGGATCCGTTACGTGGA
CGCGGAAGCCGCTTCCAATAAAGTAAAAATGCGGGAACGTTTGAAAAGGGCGGGAATCTCTCTTCCCGGCTTTGCGCCTG
TTTGGAGTTTTTCCGATGCGAGAGAAGCATTAGAATTTTTGAAATTTCCTCTTGTAATGAAACCGGCGGATAATATGGGT
GCGCGCGGCGTTATTAAGGTGGAAAATAGGGAAGAATTACAGGCCGCATTCAAACACGCGAAAAAATATTCTCCCACCGG
AGAAATGATTCTCGAAGAATACATGCCCGGTCCTGAAGTTTCTGTGGATGCCCTTACTTGGAATGGAAATTTTGTGATCA
CCGGAATCGCGGATCGAATCATTGAAAGGGAACCTTTTTTTATCGAAATGGGACACAACATGCCTTCCGCTTTAAGTTCT
TCCGTTTTGAAAGAAGTGGAAGACGTAATGTTTCGAAGTATGAAGGCTCTCGGGATTACGATAGGTGCTGGAAAAGGGGA
TATCAAAGTTACTCCTGATGGAGTTAAAGTAGGGGAGGTTGCCGCGAGATTGTCCGGCGGTTTTATGTCCGCGTTCACTT
TTCCACTTTCTTCCGGAATTAATCTGAATCGTGCGGCCATTTTAATCGCATTGGGAGAAGAGCCGGATAATCTTACTCCT
ACAATACAAAGAGTTTCGATCGAACGTTGTCTTTTGGCTCCGAGAGGAAAACTTCTTGCGATCGACGGAATCGAAGAGAT
TCGTAAGATGGAAGGAGTCAATGATCTGTTCTTCATGAATAAGATCGGAGATATCATTCGTGAACCTACGAATAACATCG
AAAAGACGGGACACGTTATCATCAGTGCCGATACGTTGAAGCAGGCAGAGTCCGTTTTCGAAAAGGTGAAAAATACCATT
CGGTTTACCTGCGACGAACTTTATTCCGTGTCCGAAAAAGAAATCCAGCAAAATGCGAGGTTACGTTTTGGAAAAGAAGT
CTGTTGGGTTTGTAAGGTTTGCGACGGAACCGATTGCGCTTCCGGAGTCCCGGGTATGGGCGGCTTGGGACGAATGCTTA
CGTTTCAAGACAATATCAATGCGTTGCGGGAATATTCGATTCTTCCTAAATACATCCGGGAACATATTCAAGCTGTCGTT
GAAACTAATTTTTTAGGAAAGGCGATTCAAACTCCTGTGATGGCCGCACCGATGACCGGGGCAGTTACGAATATGAACGG
AGCCATGGACGAATTCACCTTTGCGGCCACGTTGCTCGAAGGATGTCGGACTTCAGGCACCTTAGCCTGGTTAGGTGACG
GCGCAAGTCCGGAAAAGTATTTAATCATGCTCGAAGCGGTTCGTAAAACGAAAGCGGATGCGATTTTGATCTGTAAACCG
AGAGAAGACGAGGGGCTTTTGGAAGAAAGATTTAGGGAATCGGAAAATTCGGATCTTTTTGCAATCGGTATGGATGTGGA
CGCGGTCAACTTTAGGACGATGATGTCGAAAAATATTTCTTCGGTCACTCGAAATGTTTCCAGACTCGGAAGGATCCGTT
CTCTTACAAAATTACCTTTTATCGTCAAGGGTATTATGACTCCGCAGGATGCACAACTCGCGATCGATGCGGGTGCGGAT
TGTATCGTTGTATCCAATCATGGTGGAAGGGTTTTGGATGATATGCCGGGAACTGCCAGGGTTCTACCCGGAATTCGAAA
GGTGATAGGAGATAAAGTTCAGATTGCAGTTGATGGAGGAGTACGAAGTGGAATGGATGTTTTTAAGATGATTGCGCTCG
GTGCGGATACTGTTCTTATCGGAAGACCAATGGCAATTTTTGCGATCGGAGGAGGAGTTGCAGGAATTCGGTTTTTGATT
TCCCAATATACGGAAAATCTTTTGCAATCGATGAATGTTACCGGAGTCGGAACCTTGAAAGAAATCGGAATGGAACTTCT
CTTTCGAAAAAAAATGGACGAAGAAAATTCCGTGTCAGAATAA

Upstream 100 bases:

>100_bases
TTACTGTTAGGCGGAATTATTCGTAAGGGAAGTATCAGAATGCAGGTTGCCAAAGAGGAATCGGCAATTGCTTTTCGAAG
TTGAGTAAGGATTTTCTCTT

Downstream 100 bases:

>100_bases
GAAAATCGTTTTACTAACTCGGGATTTCCGGTTTAATATTCGAACCGCGGTACCGGGTTCCGGATCGTGTTCGGATTGAA
AATCATGGATCTCGGCTAAA

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MSLSHKIAGKTILIVGGGLLQVPIIQTARMMKLTTVVADMNGDAPGMRICDIPMVMSTKDIEGMVRESKKLATTIKIDGV
ITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRERLKRAGISLPGFAPVWSFSDAREALEFLKFPLVMKPADNMG
ARGVIKVENREELQAAFKHAKKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPFFIEMGHNMPSALSS
SVLKEVEDVMFRSMKALGITIGAGKGDIKVTPDGVKVGEVAARLSGGFMSAFTFPLSSGINLNRAAILIALGEEPDNLTP
TIQRVSIERCLLAPRGKLLAIDGIEEIRKMEGVNDLFFMNKIGDIIREPTNNIEKTGHVIISADTLKQAESVFEKVKNTI
RFTCDELYSVSEKEIQQNARLRFGKEVCWVCKVCDGTDCASGVPGMGGLGRMLTFQDNINALREYSILPKYIREHIQAVV
ETNFLGKAIQTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCRTSGTLAWLGDGASPEKYLIMLEAVRKTKADAILICKP
REDEGLLEERFRESENSDLFAIGMDVDAVNFRTMMSKNISSVTRNVSRLGRIRSLTKLPFIVKGIMTPQDAQLAIDAGAD
CIVVSNHGGRVLDDMPGTARVLPGIRKVIGDKVQIAVDGGVRSGMDVFKMIALGADTVLIGRPMAIFAIGGGVAGIRFLI
SQYTENLLQSMNVTGVGTLKEIGMELLFRKKMDEENSVSE

Sequences:

>Translated_760_residues
MSLSHKIAGKTILIVGGGLLQVPIIQTARMMKLTTVVADMNGDAPGMRICDIPMVMSTKDIEGMVRESKKLATTIKIDGV
ITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRERLKRAGISLPGFAPVWSFSDAREALEFLKFPLVMKPADNMG
ARGVIKVENREELQAAFKHAKKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPFFIEMGHNMPSALSS
SVLKEVEDVMFRSMKALGITIGAGKGDIKVTPDGVKVGEVAARLSGGFMSAFTFPLSSGINLNRAAILIALGEEPDNLTP
TIQRVSIERCLLAPRGKLLAIDGIEEIRKMEGVNDLFFMNKIGDIIREPTNNIEKTGHVIISADTLKQAESVFEKVKNTI
RFTCDELYSVSEKEIQQNARLRFGKEVCWVCKVCDGTDCASGVPGMGGLGRMLTFQDNINALREYSILPKYIREHIQAVV
ETNFLGKAIQTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCRTSGTLAWLGDGASPEKYLIMLEAVRKTKADAILICKP
REDEGLLEERFRESENSDLFAIGMDVDAVNFRTMMSKNISSVTRNVSRLGRIRSLTKLPFIVKGIMTPQDAQLAIDAGAD
CIVVSNHGGRVLDDMPGTARVLPGIRKVIGDKVQIAVDGGVRSGMDVFKMIALGADTVLIGRPMAIFAIGGGVAGIRFLI
SQYTENLLQSMNVTGVGTLKEIGMELLFRKKMDEENSVSE
>Mature_759_residues
SLSHKIAGKTILIVGGGLLQVPIIQTARMMKLTTVVADMNGDAPGMRICDIPMVMSTKDIEGMVRESKKLATTIKIDGVI
TAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRERLKRAGISLPGFAPVWSFSDAREALEFLKFPLVMKPADNMGA
RGVIKVENREELQAAFKHAKKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPFFIEMGHNMPSALSSS
VLKEVEDVMFRSMKALGITIGAGKGDIKVTPDGVKVGEVAARLSGGFMSAFTFPLSSGINLNRAAILIALGEEPDNLTPT
IQRVSIERCLLAPRGKLLAIDGIEEIRKMEGVNDLFFMNKIGDIIREPTNNIEKTGHVIISADTLKQAESVFEKVKNTIR
FTCDELYSVSEKEIQQNARLRFGKEVCWVCKVCDGTDCASGVPGMGGLGRMLTFQDNINALREYSILPKYIREHIQAVVE
TNFLGKAIQTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCRTSGTLAWLGDGASPEKYLIMLEAVRKTKADAILICKPR
EDEGLLEERFRESENSDLFAIGMDVDAVNFRTMMSKNISSVTRNVSRLGRIRSLTKLPFIVKGIMTPQDAQLAIDAGADC
IVVSNHGGRVLDDMPGTARVLPGIRKVIGDKVQIAVDGGVRSGMDVFKMIALGADTVLIGRPMAIFAIGGGVAGIRFLIS
QYTENLLQSMNVTGVGTLKEIGMELLFRKKMDEENSVSE

Specific function: Unknown

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=325, Percent_Identity=27.0769230769231, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI7705393, Length=325, Percent_Identity=27.0769230769231, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI11068137, Length=335, Percent_Identity=26.2686567164179, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1790033, Length=138, Percent_Identity=42.0289855072464, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI193208036, Length=134, Percent_Identity=38.8059701492537, Blast_Score=105, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323587, Length=141, Percent_Identity=34.7517730496454, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363140, Length=134, Percent_Identity=36.5671641791045, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI78707190, Length=134, Percent_Identity=36.5671641791045, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI78707188, Length=134, Percent_Identity=36.5671641791045, Blast_Score=100, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 82479; Mature: 82348

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSHKIAGKTILIVGGGLLQVPIIQTARMMKLTTVVADMNGDAPGMRICDIPMVMSTKD
CCCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCEEECCCEEECCHH
IEGMVRESKKLATTIKIDGVITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRER
HHHHHHHHHHHEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHH
LKRAGISLPGFAPVWSFSDAREALEFLKFPLVMKPADNMGARGVIKVENREELQAAFKHA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCEEEECCHHHHHHHHHHH
KKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPFFIEMGHNMPSALSS
HCCCCHHHHHHHHCCCCCCCEEEEEEECCCEEEEEHHHHHHCCCCCEEEECCCCHHHHHH
SVLKEVEDVMFRSMKALGITIGAGKGDIKVTPDGVKVGEVAARLSGGFMSAFTFPLSSGI
HHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCC
NLNRAAILIALGEEPDNLTPTIQRVSIERCLLAPRGKLLAIDGIEEIRKMEGVNDLFFMN
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCHHHHHHH
KIGDIIREPTNNIEKTGHVIISADTLKQAESVFEKVKNTIRFTCDELYSVSEKEIQQNAR
HHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LRFGKEVCWVCKVCDGTDCASGVPGMGGLGRMLTFQDNINALREYSILPKYIREHIQAVV
HHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ETNFLGKAIQTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCRTSGTLAWLGDGASPEKY
HHHHHHHHHCCCCEECCCCCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
LIMLEAVRKTKADAILICKPREDEGLLEERFRESENSDLFAIGMDVDAVNFRTMMSKNIS
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHH
SVTRNVSRLGRIRSLTKLPFIVKGIMTPQDAQLAIDAGADCIVVSNHGGRVLDDMPGTAR
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCEEEEECCCCEEECCCCCHHH
VLPGIRKVIGDKVQIAVDGGVRSGMDVFKMIALGADTVLIGRPMAIFAIGGGVAGIRFLI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHH
SQYTENLLQSMNVTGVGTLKEIGMELLFRKKMDEENSVSE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLSHKIAGKTILIVGGGLLQVPIIQTARMMKLTTVVADMNGDAPGMRICDIPMVMSTKD
CCCCCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHEEECCCCCCCCEEECCCEEECCHH
IEGMVRESKKLATTIKIDGVITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRER
HHHHHHHHHHHEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHH
LKRAGISLPGFAPVWSFSDAREALEFLKFPLVMKPADNMGARGVIKVENREELQAAFKHA
HHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCEEEECCHHHHHHHHHHH
KKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPFFIEMGHNMPSALSS
HCCCCHHHHHHHHCCCCCCCEEEEEEECCCEEEEEHHHHHHCCCCCEEEECCCCHHHHHH
SVLKEVEDVMFRSMKALGITIGAGKGDIKVTPDGVKVGEVAARLSGGFMSAFTFPLSSGI
HHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCC
NLNRAAILIALGEEPDNLTPTIQRVSIERCLLAPRGKLLAIDGIEEIRKMEGVNDLFFMN
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCHHHHHHH
KIGDIIREPTNNIEKTGHVIISADTLKQAESVFEKVKNTIRFTCDELYSVSEKEIQQNAR
HHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LRFGKEVCWVCKVCDGTDCASGVPGMGGLGRMLTFQDNINALREYSILPKYIREHIQAVV
HHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ETNFLGKAIQTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCRTSGTLAWLGDGASPEKY
HHHHHHHHHCCCCEECCCCCCEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
LIMLEAVRKTKADAILICKPREDEGLLEERFRESENSDLFAIGMDVDAVNFRTMMSKNIS
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHH
SVTRNVSRLGRIRSLTKLPFIVKGIMTPQDAQLAIDAGADCIVVSNHGGRVLDDMPGTAR
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCEEEEECCCCEEECCCCCHHH
VLPGIRKVIGDKVQIAVDGGVRSGMDVFKMIALGADTVLIGRPMAIFAIGGGVAGIRFLI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHH
SQYTENLLQSMNVTGVGTLKEIGMELLFRKKMDEENSVSE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA