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The map label for this gene is gst-2 [C]

Identifier: 116328506

GI number: 116328506

Start: 2161796

End: 2162461

Strand: Direct

Name: gst-2 [C]

Synonym: LBL_1855

Alternate gene names: 116328506

Gene position: 2161796-2162461 (Clockwise)

Preceding gene: 116328503

Following gene: 116328507

Centisome position: 59.81

GC content: 41.74

Gene sequence:

>666_bases
ATGATCAAACTGTACGGCTCAAATATCAGTAACTATGTAAACAAAGTAAAGCTGGGGCTTTTGGAAAAAGGATTAGAATA
CGAACAAATTAGGGTTTCTCCTTTTCAAGACGAAGAATTTCTAAAGATCAGCCCGATGGGAAAAATTCCTGTTCTGGAAC
TAGACGGAAAATTCATATCCGAGTCGGGAGCTATTTTAGAATTCTTAGATACGATTTTTCCCAAAACACCAAAACTAATC
CCGGAAGATCCCTGGGAAGCCGCAAGAGTCAGGGAAATTACGACGATCATAGAGATCTATCTGGGCATTCCCGCGAGAAG
AATCTATCTTCTGAGCATGAAAGGAAAAGCCGTTTCTCCCGAACTGATCGTAGAAGTTCATCCAATTCTGGTCAAAGGAG
TAAAAGCGCTTCAAAGAGTGGTTCGATTTTCTCCTTATATCGCAGGAGACGTTTTTACGATGGCGGATTGCTCCGCTTTT
GCAAACCTCTCTATGATCGACGAAGAACTGCGCCCTATTTATCCGGACAATCATCCCCTGGATTTGCTAAACGGCTGGAA
AGAATATCTCGCATTTATGAAAATAGAAGAGGGTCCGGCGCTCGTAGAGAAAGAAAAACAAACTCTTAAAAAAATCATTG
CAAGAGCCAAAGCGAGAATCGAATGA

Upstream 100 bases:

>100_bases
TCCAATCATGAATCCACATTCATTCGATCTTTAAGACAAACCGCCCAATCATCCGGAAAAAGTGTTTGCCAATGAACATC
GGTCCTTATTTTTCCTTTCC

Downstream 100 bases:

>100_bases
ACGTCGAAATTCCGAGCAGTAGTTTAAAATTGATTTGACTCTCTCAGTATGCAAAATAGCCTACTGTGGTTTCTATGGAA
CCAGAAAAAGTAATTTCGAT

Product: glutathione transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MIKLYGSNISNYVNKVKLGLLEKGLEYEQIRVSPFQDEEFLKISPMGKIPVLELDGKFISESGAILEFLDTIFPKTPKLI
PEDPWEAARVREITTIIEIYLGIPARRIYLLSMKGKAVSPELIVEVHPILVKGVKALQRVVRFSPYIAGDVFTMADCSAF
ANLSMIDEELRPIYPDNHPLDLLNGWKEYLAFMKIEEGPALVEKEKQTLKKIIARAKARIE

Sequences:

>Translated_221_residues
MIKLYGSNISNYVNKVKLGLLEKGLEYEQIRVSPFQDEEFLKISPMGKIPVLELDGKFISESGAILEFLDTIFPKTPKLI
PEDPWEAARVREITTIIEIYLGIPARRIYLLSMKGKAVSPELIVEVHPILVKGVKALQRVVRFSPYIAGDVFTMADCSAF
ANLSMIDEELRPIYPDNHPLDLLNGWKEYLAFMKIEEGPALVEKEKQTLKKIIARAKARIE
>Mature_221_residues
MIKLYGSNISNYVNKVKLGLLEKGLEYEQIRVSPFQDEEFLKISPMGKIPVLELDGKFISESGAILEFLDTIFPKTPKLI
PEDPWEAARVREITTIIEIYLGIPARRIYLLSMKGKAVSPELIVEVHPILVKGVKALQRVVRFSPYIAGDVFTMADCSAF
ANLSMIDEELRPIYPDNHPLDLLNGWKEYLAFMKIEEGPALVEKEKQTLKKIIARAKARIE

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=162, Percent_Identity=30.8641975308642, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922526, Length=212, Percent_Identity=30.188679245283, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 25089; Mature: 25089

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLYGSNISNYVNKVKLGLLEKGLEYEQIRVSPFQDEEFLKISPMGKIPVLELDGKFIS
CEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCCCCEEEECCCCCC
ESGAILEFLDTIFPKTPKLIPEDPWEAARVREITTIIEIYLGIPARRIYLLSMKGKAVSP
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ELIVEVHPILVKGVKALQRVVRFSPYIAGDVFTMADCSAFANLSMIDEELRPIYPDNHPL
HHHEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DLLNGWKEYLAFMKIEEGPALVEKEKQTLKKIIARAKARIE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKLYGSNISNYVNKVKLGLLEKGLEYEQIRVSPFQDEEFLKISPMGKIPVLELDGKFIS
CEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCCCCEEEECCCCCC
ESGAILEFLDTIFPKTPKLIPEDPWEAARVREITTIIEIYLGIPARRIYLLSMKGKAVSP
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ELIVEVHPILVKGVKALQRVVRFSPYIAGDVFTMADCSAFANLSMIDEELRPIYPDNHPL
HHHEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DLLNGWKEYLAFMKIEEGPALVEKEKQTLKKIIARAKARIE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11900268 [H]