| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is sppA-1 [H]
Identifier: 116328293
GI number: 116328293
Start: 1907319
End: 1909067
Strand: Reverse
Name: sppA-1 [H]
Synonym: LBL_1628
Alternate gene names: 116328293
Gene position: 1909067-1907319 (Counterclockwise)
Preceding gene: 116328299
Following gene: 116328290
Centisome position: 52.82
GC content: 38.94
Gene sequence:
>1749_bases ATGTTTCTAAATTTTCTCCAAATCGTGCTGATTCCGTTTCGACTCATTTTTCAACTGATCCGTTGGATTCGATTTCGATT CATATCGAATCGTCGCTACTTTTTGGAAATTCCATCCGAATTTACGAACTATCGTAAGTCTTTTTTAATGAGATTACTTT CCTCCAAAGAGGAAAATGCTTTTTTCACGGATTTTCTGTTGGAACTCAAACTACTCTCTCAAGTCCCCGGGTTGAAAAAA GTTTCGGTTTTGATTCAACAACCGGAATACGGGTTCAGTGAAGTCTTAAGCATAGCGGAAAGGTTACGAATTCTGAAAGA ATCCGGAATCACTCTAGAGGGATTTGCACTTACTGGTGGACTCAAATCCTTGTTCCTTTTAGGAATCTGTAATGAAAGAT TCAGTTCGGAATCGTCGGAATTTTTTCCCGTTTTACCCTCTACAGAGTCGTTTTTTTTCGGAAATGCCGGCAAAAAATGG GGAATAAAAGTGGAAACTTTCCAAAGTGGGCCGTATAAATCCTTCGGAGAATCCTTTCAAAGGGATAAATTCTCACCAAA AGCGCGCGAAAATCTGAACTCTCTCTTAAGGCAGATGATGGACGATTTGGATTTACTTTTTAAACGTTATACCGGCTTTG CACTCGAAATTTTTTCCGAACCTTTTCTATCCGCAAAAACGCTCCAGAAAAGAGAATTCATCACCGGATTTCTAAACGAA GAGGATTTTAAGGAAAATTTTCTTTATTTAAACTACGAAAAAGAAAATCAAAAGCCGCTCGCAAAAGAATTAACCCTTTC TTCTTTATATCGTTTTTCTAAATTAGTAAATTTTAAACTTCTTCCCAAGAGGCCTCCCGTCGTCGCGGTTCTTCCGCTCA AAGGGACGATTCATCACGATACGATCGGCAAGGGGGAAGGTAAAACGGAAGGTATTTCGTATTATTCGGTTCGAAATGCA CTCAAAGAACTGAGAGACGAATCTTCCGTAAAAGCGGTCGTTCTAGAAGTGGATTCTCCCGGAGGTTCAGCCTTTGTTTC TGAACTTCTCTATCAAGAAATTCTAAAATTACAAAAAAAGAAACCGGTCTATGCATATGTACAAAACGTTTCGGCAAGCG GGGGTTATTATCTTTCCTGCGGCGCTTCAAAAATTTATGCCTCTCCATACGGAATCGTCGGAAGTATTGGTAGTCTTTCT CTTCGTTTGGATCTGAAAAATTTTTACTCTAAATTGGGGGTGACGAAGGACAGAGTCGGCTTTTACAAATACAGAGATCT TCTTTCCGAGTATGGACCGATACATCCGGAATCCAGAAAACTAATGAGGCAGGAAATCAAAGAATCGGAAGGGCTTTTTT ATAAGCGAGTCGCCGACGCGAGAAAAATTCCAATCTCGACTTTGGATAAACGATTCGGTCAGGGAAGAGTTTTCACATCT AGCCGATTTTTAAAGGAAAAGATGATCGATTCCATCACTGACTTTTTGGGTTTATTAGAAGATATTAAACAAGAATTGAA AACACAACGGTTGGAGATTCGATACTTACCTACCCTTTTCACATTTCAAAATTTTCTTAGATCTTTAAAGCCAGGGTTTT TAATAAATCGATTGGATGGAAATTTCGCTTCTTCATTCCCGGAAATTTTGCAATCCACTTCCATGAAGATGACCGATCCC TTGAAAAGAAAATTTCAATGCACGGAAGTGGAATTTTTGTTACAATCCGCGTTTTGGAACCAAAAATAA
Upstream 100 bases:
>100_bases CTCTCTCTTTTTAGGATTTATGGCGTACTAAAATCTGAAAACTCCTTTCCTAAAAGAAATTCTTCTTTTTCAGTAGGAAT CTAATTTTCAAACTGGCGTC
Downstream 100 bases:
>100_bases TTCTAGGTTTTTCGTCTGATTCGCCAAGATTTTCAGCCGTCGAACTCACGTTATTTAGGAGAAGTCGATGTGTGCCTGCT GTATTATTTCGAAGCGGCTT
Product: Signal peptide peptidase (protease IV)
Products: NA
Alternate protein names: Endopeptidase IV; Protease IV homolog; Signal peptide peptidase [H]
Number of amino acids: Translated: 582; Mature: 582
Protein sequence:
>582_residues MFLNFLQIVLIPFRLIFQLIRWIRFRFISNRRYFLEIPSEFTNYRKSFLMRLLSSKEENAFFTDFLLELKLLSQVPGLKK VSVLIQQPEYGFSEVLSIAERLRILKESGITLEGFALTGGLKSLFLLGICNERFSSESSEFFPVLPSTESFFFGNAGKKW GIKVETFQSGPYKSFGESFQRDKFSPKARENLNSLLRQMMDDLDLLFKRYTGFALEIFSEPFLSAKTLQKREFITGFLNE EDFKENFLYLNYEKENQKPLAKELTLSSLYRFSKLVNFKLLPKRPPVVAVLPLKGTIHHDTIGKGEGKTEGISYYSVRNA LKELRDESSVKAVVLEVDSPGGSAFVSELLYQEILKLQKKKPVYAYVQNVSASGGYYLSCGASKIYASPYGIVGSIGSLS LRLDLKNFYSKLGVTKDRVGFYKYRDLLSEYGPIHPESRKLMRQEIKESEGLFYKRVADARKIPISTLDKRFGQGRVFTS SRFLKEKMIDSITDFLGLLEDIKQELKTQRLEIRYLPTLFTFQNFLRSLKPGFLINRLDGNFASSFPEILQSTSMKMTDP LKRKFQCTEVEFLLQSAFWNQK
Sequences:
>Translated_582_residues MFLNFLQIVLIPFRLIFQLIRWIRFRFISNRRYFLEIPSEFTNYRKSFLMRLLSSKEENAFFTDFLLELKLLSQVPGLKK VSVLIQQPEYGFSEVLSIAERLRILKESGITLEGFALTGGLKSLFLLGICNERFSSESSEFFPVLPSTESFFFGNAGKKW GIKVETFQSGPYKSFGESFQRDKFSPKARENLNSLLRQMMDDLDLLFKRYTGFALEIFSEPFLSAKTLQKREFITGFLNE EDFKENFLYLNYEKENQKPLAKELTLSSLYRFSKLVNFKLLPKRPPVVAVLPLKGTIHHDTIGKGEGKTEGISYYSVRNA LKELRDESSVKAVVLEVDSPGGSAFVSELLYQEILKLQKKKPVYAYVQNVSASGGYYLSCGASKIYASPYGIVGSIGSLS LRLDLKNFYSKLGVTKDRVGFYKYRDLLSEYGPIHPESRKLMRQEIKESEGLFYKRVADARKIPISTLDKRFGQGRVFTS SRFLKEKMIDSITDFLGLLEDIKQELKTQRLEIRYLPTLFTFQNFLRSLKPGFLINRLDGNFASSFPEILQSTSMKMTDP LKRKFQCTEVEFLLQSAFWNQK >Mature_582_residues MFLNFLQIVLIPFRLIFQLIRWIRFRFISNRRYFLEIPSEFTNYRKSFLMRLLSSKEENAFFTDFLLELKLLSQVPGLKK VSVLIQQPEYGFSEVLSIAERLRILKESGITLEGFALTGGLKSLFLLGICNERFSSESSEFFPVLPSTESFFFGNAGKKW GIKVETFQSGPYKSFGESFQRDKFSPKARENLNSLLRQMMDDLDLLFKRYTGFALEIFSEPFLSAKTLQKREFITGFLNE EDFKENFLYLNYEKENQKPLAKELTLSSLYRFSKLVNFKLLPKRPPVVAVLPLKGTIHHDTIGKGEGKTEGISYYSVRNA LKELRDESSVKAVVLEVDSPGGSAFVSELLYQEILKLQKKKPVYAYVQNVSASGGYYLSCGASKIYASPYGIVGSIGSLS LRLDLKNFYSKLGVTKDRVGFYKYRDLLSEYGPIHPESRKLMRQEIKESEGLFYKRVADARKIPISTLDKRFGQGRVFTS SRFLKEKMIDSITDFLGLLEDIKQELKTQRLEIRYLPTLFTFQNFLRSLKPGFLINRLDGNFASSFPEILQSTSMKMTDP LKRKFQCTEVEFLLQSAFWNQK
Specific function: Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane [H]
COG id: COG0616
COG function: function code OU; Periplasmic serine proteases (ClpP class)
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S49 family [H]
Homologues:
Organism=Escherichia coli, GI1788064, Length=436, Percent_Identity=25.9174311926606, Blast_Score=108, Evalue=1e-24, Organism=Escherichia coli, GI1787527, Length=150, Percent_Identity=31.3333333333333, Blast_Score=69, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004634 - InterPro: IPR004635 - InterPro: IPR002142 [H]
Pfam domain/function: PF01343 Peptidase_S49 [H]
EC number: 3.4.21.-
Molecular weight: Translated: 67228; Mature: 67228
Theoretical pI: Translated: 10.03; Mature: 10.03
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFLNFLQIVLIPFRLIFQLIRWIRFRFISNRRYFLEIPSEFTNYRKSFLMRLLSSKEENA CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCH FFTDFLLELKLLSQVPGLKKVSVLIQQPEYGFSEVLSIAERLRILKESGITLEGFALTGG HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHH LKSLFLLGICNERFSSESSEFFPVLPSTESFFFGNAGKKWGIKVETFQSGPYKSFGESFQ HHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHH RDKFSPKARENLNSLLRQMMDDLDLLFKRYTGFALEIFSEPFLSAKTLQKREFITGFLNE HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCC EDFKENFLYLNYEKENQKPLAKELTLSSLYRFSKLVNFKLLPKRPPVVAVLPLKGTIHHD HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCEEEEEECCCCCCCC TIGKGEGKTEGISYYSVRNALKELRDESSVKAVVLEVDSPGGSAFVSELLYQEILKLQKK CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHC KPVYAYVQNVSASGGYYLSCGASKIYASPYGIVGSIGSLSLRLDLKNFYSKLGVTKDRVG CCHHHHHHCCCCCCCEEEEECCCEEECCCCCHHCCCCCEEEEEEHHHHHHHHCCCHHHHH FYKYRDLLSEYGPIHPESRKLMRQEIKESEGLFYKRVADARKIPISTLDKRFGQGRVFTS HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCCCEEHH SRFLKEKMIDSITDFLGLLEDIKQELKTQRLEIRYLPTLFTFQNFLRSLKPGFLINRLDG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHCCCCCEEECCCC NFASSFPEILQSTSMKMTDPLKRKFQCTEVEFLLQSAFWNQK CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MFLNFLQIVLIPFRLIFQLIRWIRFRFISNRRYFLEIPSEFTNYRKSFLMRLLSSKEENA CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCH FFTDFLLELKLLSQVPGLKKVSVLIQQPEYGFSEVLSIAERLRILKESGITLEGFALTGG HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHH LKSLFLLGICNERFSSESSEFFPVLPSTESFFFGNAGKKWGIKVETFQSGPYKSFGESFQ HHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHH RDKFSPKARENLNSLLRQMMDDLDLLFKRYTGFALEIFSEPFLSAKTLQKREFITGFLNE HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHCCC EDFKENFLYLNYEKENQKPLAKELTLSSLYRFSKLVNFKLLPKRPPVVAVLPLKGTIHHD HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCEEEEEECCCCCCCC TIGKGEGKTEGISYYSVRNALKELRDESSVKAVVLEVDSPGGSAFVSELLYQEILKLQKK CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHC KPVYAYVQNVSASGGYYLSCGASKIYASPYGIVGSIGSLSLRLDLKNFYSKLGVTKDRVG CCHHHHHHCCCCCCCEEEEECCCEEECCCCCHHCCCCCEEEEEEHHHHHHHHCCCHHHHH FYKYRDLLSEYGPIHPESRKLMRQEIKESEGLFYKRVADARKIPISTLDKRFGQGRVFTS HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCCCCCEEHH SRFLKEKMIDSITDFLGLLEDIKQELKTQRLEIRYLPTLFTFQNFLRSLKPGFLINRLDG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHCCCCCEEECCCC NFASSFPEILQSTSMKMTDPLKRKFQCTEVEFLLQSAFWNQK CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]