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The map label for this gene is zraS [C]

Identifier: 116328266

GI number: 116328266

Start: 1869608

End: 1870756

Strand: Direct

Name: zraS [C]

Synonym: LBL_1594

Alternate gene names: 116328266

Gene position: 1869608-1870756 (Clockwise)

Preceding gene: 116328265

Following gene: 116328268

Centisome position: 51.73

GC content: 40.03

Gene sequence:

>1149_bases
ATGAATAGATGGAAATTCCTTTTTTTAGAAGATTCCTTAGTTGATTTGGAATTAATTCAAAGGCAATTGAATCGTGCTAA
GATTGATTACTACCCGATTCATGTCAGTGATTCGGAAGGATTCTCACAAGCGATCCTGGATCAAAAACCTCATCTAATCC
TGTCCGATTTCAGTCTTCCAAAATACGACGGGTTTTCAGCTTTGAAATTGGCTAAAAAAATCTGTCCTACAACGCCGTTC
ATATTTGTTTCGGGAACTTATGGCGAAGATGCGGCTATACAAACGCTTACCATGGGCGCGACTGATTATGTTCTCAAGGA
CAGGATTGAAAAACTTCTTCCCGCGGTACAAAGAGCCTTACACGAATTAGAAGATCATGAATTACGAATCAAGGCGGAAA
AAGAAAGATACGAATTGGAAGAACAACTTAGACAAAGCCAAAAATTAGAAGCAATGGGTGTGATGGCGGGAACCATGGCA
CATGAGATCAACAATCCTTTGATCGCAATTTCGGAATACGCGGCAATAATAGCAAAAGGGGAAGTGGACGCCGATAAAAC
AAAGCAATTGGCTTCCAAGATTCGAGACGAAAGTGCACGAATCTCCACCATTATGAAAAATCTTCTTCGGTTTTCCAGAG
ACGATAAGGGTTCTCTTCGTCCCGTGGAAGTCGGCGAAATTCTTGTGAAACTAGAGTCGATCACACAACAAATTTTTAAA
ATGAATCGAATCGACGTTTCTTGGAAAAACGTTGAACCGGGGCATTTGATTCAATGTAGGGAAGGACAGATCCTTCAAAT
CCTCGTAAATCTTGTGAATAATTCCGTAGATAGTCTGAATCAAAAATATCCGGAATATGACGAAGAAAAGAGAATTATCT
TAGAAAATTCCATCGTAAAAGAAGATAACAAGAGATATGCGGAATTTGCAGTTCAGGATTTCGGCACAGGAATCCCGATC
GATATTCAAAAATCCGTCTTTAAAACCTTTTTTACTACGAAGGCGGCTGATAAAGGGACTGGTCTGGGTTTGTCAGTCAG
TTTAGGGATTGCAAAGGAACACGGAGGAAATCTTGACTTTGAAAGCGAACCTGGCAGATATACTCGTTTCTATTTAAGAA
TTCCGATCTTTGACCCGAACAACCAATAA

Upstream 100 bases:

>100_bases
GTGAATAAGGGTTCCAAATTTTCATTTACTCTTCCGAAACTTTCGGAGAACGAAAATATTTATGAAGACATCATAAAAAT
ATAGCAAAACGGTATTAAAC

Downstream 100 bases:

>100_bases
GCTTTGTCAAAACATAATTCTGTATTTCTTAGATAAGGAAAACTTTTTCTTAAAGTTGGGCGTATTCCTCGCACTTTGGT
GATTCAATCTGTGAGAGATC

Product: sensor histidine kinase of a two component response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNRWKFLFLEDSLVDLELIQRQLNRAKIDYYPIHVSDSEGFSQAILDQKPHLILSDFSLPKYDGFSALKLAKKICPTTPF
IFVSGTYGEDAAIQTLTMGATDYVLKDRIEKLLPAVQRALHELEDHELRIKAEKERYELEEQLRQSQKLEAMGVMAGTMA
HEINNPLIAISEYAAIIAKGEVDADKTKQLASKIRDESARISTIMKNLLRFSRDDKGSLRPVEVGEILVKLESITQQIFK
MNRIDVSWKNVEPGHLIQCREGQILQILVNLVNNSVDSLNQKYPEYDEEKRIILENSIVKEDNKRYAEFAVQDFGTGIPI
DIQKSVFKTFFTTKAADKGTGLGLSVSLGIAKEHGGNLDFESEPGRYTRFYLRIPIFDPNNQ

Sequences:

>Translated_382_residues
MNRWKFLFLEDSLVDLELIQRQLNRAKIDYYPIHVSDSEGFSQAILDQKPHLILSDFSLPKYDGFSALKLAKKICPTTPF
IFVSGTYGEDAAIQTLTMGATDYVLKDRIEKLLPAVQRALHELEDHELRIKAEKERYELEEQLRQSQKLEAMGVMAGTMA
HEINNPLIAISEYAAIIAKGEVDADKTKQLASKIRDESARISTIMKNLLRFSRDDKGSLRPVEVGEILVKLESITQQIFK
MNRIDVSWKNVEPGHLIQCREGQILQILVNLVNNSVDSLNQKYPEYDEEKRIILENSIVKEDNKRYAEFAVQDFGTGIPI
DIQKSVFKTFFTTKAADKGTGLGLSVSLGIAKEHGGNLDFESEPGRYTRFYLRIPIFDPNNQ
>Mature_382_residues
MNRWKFLFLEDSLVDLELIQRQLNRAKIDYYPIHVSDSEGFSQAILDQKPHLILSDFSLPKYDGFSALKLAKKICPTTPF
IFVSGTYGEDAAIQTLTMGATDYVLKDRIEKLLPAVQRALHELEDHELRIKAEKERYELEEQLRQSQKLEAMGVMAGTMA
HEINNPLIAISEYAAIIAKGEVDADKTKQLASKIRDESARISTIMKNLLRFSRDDKGSLRPVEVGEILVKLESITQQIFK
MNRIDVSWKNVEPGHLIQCREGQILQILVNLVNNSVDSLNQKYPEYDEEKRIILENSIVKEDNKRYAEFAVQDFGTGIPI
DIQKSVFKTFFTTKAADKGTGLGLSVSLGIAKEHGGNLDFESEPGRYTRFYLRIPIFDPNNQ

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=27.1604938271605, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=28.6274509803922, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790300, Length=257, Percent_Identity=26.0700389105058, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=25.2173913043478, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789149, Length=316, Percent_Identity=24.0506329113924, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43473; Mature: 43473

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRWKFLFLEDSLVDLELIQRQLNRAKIDYYPIHVSDSEGFSQAILDQKPHLILSDFSLP
CCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCEEEECCCCC
KYDGFSALKLAKKICPTTPFIFVSGTYGEDAAIQTLTMGATDYVLKDRIEKLLPAVQRAL
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
HELEDHELRIKAEKERYELEEQLRQSQKLEAMGVMAGTMAHEINNPLIAISEYAAIIAKG
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHEECC
EVDADKTKQLASKIRDESARISTIMKNLLRFSRDDKGSLRPVEVGEILVKLESITQQIFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MNRIDVSWKNVEPGHLIQCREGQILQILVNLVNNSVDSLNQKYPEYDEEKRIILENSIVK
HHCCEEEECCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCHHC
EDNKRYAEFAVQDFGTGIPIDIQKSVFKTFFTTKAADKGTGLGLSVSLGIAKEHGGNLDF
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCC
ESEPGRYTRFYLRIPIFDPNNQ
CCCCCCEEEEEEEEEEECCCCC
>Mature Secondary Structure
MNRWKFLFLEDSLVDLELIQRQLNRAKIDYYPIHVSDSEGFSQAILDQKPHLILSDFSLP
CCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCCEEEECCCCC
KYDGFSALKLAKKICPTTPFIFVSGTYGEDAAIQTLTMGATDYVLKDRIEKLLPAVQRAL
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
HELEDHELRIKAEKERYELEEQLRQSQKLEAMGVMAGTMAHEINNPLIAISEYAAIIAKG
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHEECC
EVDADKTKQLASKIRDESARISTIMKNLLRFSRDDKGSLRPVEVGEILVKLESITQQIFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MNRIDVSWKNVEPGHLIQCREGQILQILVNLVNNSVDSLNQKYPEYDEEKRIILENSIVK
HHCCEEEECCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEECCHHC
EDNKRYAEFAVQDFGTGIPIDIQKSVFKTFFTTKAADKGTGLGLSVSLGIAKEHGGNLDF
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCC
ESEPGRYTRFYLRIPIFDPNNQ
CCCCCCEEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA