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The map label for this gene is fadH [H]

Identifier: 116328257

GI number: 116328257

Start: 1856577

End: 1858586

Strand: Reverse

Name: fadH [H]

Synonym: LBL_1585

Alternate gene names: 116328257

Gene position: 1858586-1856577 (Counterclockwise)

Preceding gene: 116328259

Following gene: 116328256

Centisome position: 51.42

GC content: 44.08

Gene sequence:

>2010_bases
ATGAAATATTTAGAAATTTTCCAACCGATCCAAATCGGTTCGATCACTCTTCCGAACAGAGTTATCATGGGCTCTATGCA
TTTAGGATTGGAAGGAATGCCAATGCCTGTGGAAAGAATGATCGCCTTCTACGGTAGACGTTTTGATGGAGGTGCTTGTT
TTATCACGACAGGAGGAATCGCCGTTAACCACGCGGGAAGGGGGGCCAATATTTTCTTTAATTTTCAGAAAGAAGAGGAC
TGTAAGGAATTATCCATCGTGGCAAACACACTCAAACCAAAAGGAATTTTTTGCGCTCAACTCTTTCACGCAGGAAGATA
CTCATATCATAGAGACCTAGTCGCTCCTTCTGCATTCAGGGCACCTATCAATCGCTTTATTCCAAAAGCCCTTTCTGAAG
AAGAAGCCTGGAAAACCGTAGAAGATTTCGGAGACTCTGCGCTCAAAGCGAAAGAAATAGGCTTCGGCGCCGTAGAAGTG
ATGGGAAGCGAAGGTTACTTAATAAACCAATTTTTTTCTCCCGTTACAAATCATAGAGAGGATTTCTTTGGTGGAAGTCC
CGAGAAAAGAATGAACTTTGCGGTCGAAGTCATGAAAAACGTACGCAAAAAGGTGGGAAAAGATTTTCCAGTAATTTATC
GTATGTCTGGAATTGATTTGATCCCAGGCAATCCAACTTTTGAAGAAGTGATCCTTCTTGCTGAAAAACTAAAAGCAACA
GGTGCCGATGCACTCAATATAGGAATCGGTTGGCACGAATCCAGAATCCCTACAATTTCCATGCTTGTTCCCAGAGGGGC
CTGGGCAAAAATTTCCGGAGAAATCAAAGAAAAAATCAAGGATATTCCGATCATCGCATCGAATCGAGTCAATATGCCGG
AAGTTATGACTCGGATTCTAAAAAACCACGAAGCGGACATATTAAGCATGGCAAGACCTTTTTTAGCGGATCCTGATATC
GTGAACAAGATTCGAGCGGATCAAGAAGAAAGAATCAATACCTGCATCGCCTGCAACCAGGCTTGCTTAGACCATACATT
CAAAGAACAATTGGTCTCCTGTTTGGTCAATCCTTCCGCCAATAGGGAACTTGAAATCGGTAAATTGAAAGTAGCAGACA
AAAAGCATGTGGTAGTAGTCGGTTCCGGACCTGGAGGACTTGAATCGGCAAGGATCAGTGCGATCCGAGGCCATAAAGTA
ACCGTGTTAGAAGCAACCGATAAGATCGGAGGACAACTCAATCTTGCCGCACAAATACCGGGGAAATCGGAATTCTTTGA
AACAATCCGTTATTTCAAGAACGAACTTAAAAACTTAGGAGTGGAAATTCAATTTGGTCATCATGCCACGTTAGACAGCA
TTCTCGCACTCAGACCGGACGCCGTCATTTTTGCGACCGGGGTCAAACCAAGGGAATTTTCACTTCCGGGAATGGAAAAA
AAGAAAACGGCTTCTTATGCGGATTATCTTTCCGGAAAATTCAAGCCGGGTGATCAGGTGGCGATTATCGGAGGAGGAGG
AATCGGTTGTGACGTAGCTCATAAACTTACGGAAGAAGATTCTCCTACGATTGATTCCTACTTCCATCGCTACAATGTGA
AATCTTATACGAACGCGCAGATCCAAAAAGAAAAACCGAATCGCAAGGTTTCCATCTTTCGAAGATCCGGAAAAATCGGA
TCCGGCCTTGGAGCGACAACCGCCTGGGCCTTACTTCAAGAACTGGAATCGAAAGATGTCGGATTTTACACTTCTCTTAA
TTATAAAGAAGTCACGGATCAAGGACTGGTCGTTGAAACCAAAAAAGACGGACCGATCACGATCGAATGCGATTCTATCA
TTCTTTGCGCGGGACAACTCAGCGAGGTTTCCCTTTACGAAGAATTCAAGGCGAAATTCCCGGAAATTCCGTCGTATCTG
ATCGGAGGTGCAAAGGATGCTTCCGGAATCGATGCAAAACGTGCGATGTTGGAAGGATTTGAGGCGGCGCTTGGAATCGG
AGTAAATTAA

Upstream 100 bases:

>100_bases
AATCGAAAACGATTTTTAAAGATGAAACATAATTCTCTTGCCCATTTTCTAATCCGTTTTCAAAATAGAAAGGAAAGATT
CTCCATAAAAAAGGTTTGTT

Downstream 100 bases:

>100_bases
AATTGTCGGTTTCCCGCTTTTTTCGTTTCATTTGAGTTCTCCTCTTAGGTGGTACAAAAACCGTACCTGAGTAGGAGGAG
AATTCCTTGTTTTATAAGCT

Product: 2,4-dienoyl-CoA reductase (NADPH)

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKYLEIFQPIQIGSITLPNRVIMGSMHLGLEGMPMPVERMIAFYGRRFDGGACFITTGGIAVNHAGRGANIFFNFQKEED
CKELSIVANTLKPKGIFCAQLFHAGRYSYHRDLVAPSAFRAPINRFIPKALSEEEAWKTVEDFGDSALKAKEIGFGAVEV
MGSEGYLINQFFSPVTNHREDFFGGSPEKRMNFAVEVMKNVRKKVGKDFPVIYRMSGIDLIPGNPTFEEVILLAEKLKAT
GADALNIGIGWHESRIPTISMLVPRGAWAKISGEIKEKIKDIPIIASNRVNMPEVMTRILKNHEADILSMARPFLADPDI
VNKIRADQEERINTCIACNQACLDHTFKEQLVSCLVNPSANRELEIGKLKVADKKHVVVVGSGPGGLESARISAIRGHKV
TVLEATDKIGGQLNLAAQIPGKSEFFETIRYFKNELKNLGVEIQFGHHATLDSILALRPDAVIFATGVKPREFSLPGMEK
KKTASYADYLSGKFKPGDQVAIIGGGGIGCDVAHKLTEEDSPTIDSYFHRYNVKSYTNAQIQKEKPNRKVSIFRRSGKIG
SGLGATTAWALLQELESKDVGFYTSLNYKEVTDQGLVVETKKDGPITIECDSIILCAGQLSEVSLYEEFKAKFPEIPSYL
IGGAKDASGIDAKRAMLEGFEAALGIGVN

Sequences:

>Translated_669_residues
MKYLEIFQPIQIGSITLPNRVIMGSMHLGLEGMPMPVERMIAFYGRRFDGGACFITTGGIAVNHAGRGANIFFNFQKEED
CKELSIVANTLKPKGIFCAQLFHAGRYSYHRDLVAPSAFRAPINRFIPKALSEEEAWKTVEDFGDSALKAKEIGFGAVEV
MGSEGYLINQFFSPVTNHREDFFGGSPEKRMNFAVEVMKNVRKKVGKDFPVIYRMSGIDLIPGNPTFEEVILLAEKLKAT
GADALNIGIGWHESRIPTISMLVPRGAWAKISGEIKEKIKDIPIIASNRVNMPEVMTRILKNHEADILSMARPFLADPDI
VNKIRADQEERINTCIACNQACLDHTFKEQLVSCLVNPSANRELEIGKLKVADKKHVVVVGSGPGGLESARISAIRGHKV
TVLEATDKIGGQLNLAAQIPGKSEFFETIRYFKNELKNLGVEIQFGHHATLDSILALRPDAVIFATGVKPREFSLPGMEK
KKTASYADYLSGKFKPGDQVAIIGGGGIGCDVAHKLTEEDSPTIDSYFHRYNVKSYTNAQIQKEKPNRKVSIFRRSGKIG
SGLGATTAWALLQELESKDVGFYTSLNYKEVTDQGLVVETKKDGPITIECDSIILCAGQLSEVSLYEEFKAKFPEIPSYL
IGGAKDASGIDAKRAMLEGFEAALGIGVN
>Mature_669_residues
MKYLEIFQPIQIGSITLPNRVIMGSMHLGLEGMPMPVERMIAFYGRRFDGGACFITTGGIAVNHAGRGANIFFNFQKEED
CKELSIVANTLKPKGIFCAQLFHAGRYSYHRDLVAPSAFRAPINRFIPKALSEEEAWKTVEDFGDSALKAKEIGFGAVEV
MGSEGYLINQFFSPVTNHREDFFGGSPEKRMNFAVEVMKNVRKKVGKDFPVIYRMSGIDLIPGNPTFEEVILLAEKLKAT
GADALNIGIGWHESRIPTISMLVPRGAWAKISGEIKEKIKDIPIIASNRVNMPEVMTRILKNHEADILSMARPFLADPDI
VNKIRADQEERINTCIACNQACLDHTFKEQLVSCLVNPSANRELEIGKLKVADKKHVVVVGSGPGGLESARISAIRGHKV
TVLEATDKIGGQLNLAAQIPGKSEFFETIRYFKNELKNLGVEIQFGHHATLDSILALRPDAVIFATGVKPREFSLPGMEK
KKTASYADYLSGKFKPGDQVAIIGGGGIGCDVAHKLTEEDSPTIDSYFHRYNVKSYTNAQIQKEKPNRKVSIFRRSGKIG
SGLGATTAWALLQELESKDVGFYTSLNYKEVTDQGLVVETKKDGPITIECDSIILCAGQLSEVSLYEEFKAKFPEIPSYL
IGGAKDASGIDAKRAMLEGFEAALGIGVN

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=680, Percent_Identity=41.4705882352941, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1787939, Length=358, Percent_Identity=27.0949720670391, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559804, Length=317, Percent_Identity=24.9211356466877, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=314, Percent_Identity=24.203821656051, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI72001454, Length=352, Percent_Identity=24.4318181818182, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565138, Length=335, Percent_Identity=24.1791044776119, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559802, Length=317, Percent_Identity=24.6056782334385, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540738, Length=311, Percent_Identity=23.4726688102894, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325086, Length=348, Percent_Identity=24.7126436781609, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73505; Mature: 73505

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLEIFQPIQIGSITLPNRVIMGSMHLGLEGMPMPVERMIAFYGRRFDGGACFITTGGI
CCCHHHCCCCEECEEECCCEEEEEEHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCE
AVNHAGRGANIFFNFQKEEDCKELSIVANTLKPKGIFCAQLFHAGRYSYHRDLVAPSAFR
EEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCHHHH
APINRFIPKALSEEEAWKTVEDFGDSALKAKEIGFGAVEVMGSEGYLINQFFSPVTNHRE
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCHH
DFFGGSPEKRMNFAVEVMKNVRKKVGKDFPVIYRMSGIDLIPGNPTFEEVILLAEKLKAT
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHC
GADALNIGIGWHESRIPTISMLVPRGAWAKISGEIKEKIKDIPIIASNRVNMPEVMTRIL
CCCEEEEECCCCCCCCCEEEEEECCCCCHHHCHHHHHHHHCCCEEECCCCCHHHHHHHHH
KNHEADILSMARPFLADPDIVNKIRADQEERINTCIACNQACLDHTFKEQLVSCLVNPSA
HCCCHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
NRELEIGKLKVADKKHVVVVGSGPGGLESARISAIRGHKVTVLEATDKIGGQLNLAAQIP
CCEEEEEEEEECCCCEEEEEECCCCCCCHHHEEEECCCEEEEEECCCCCCCEEEEEEECC
GKSEFFETIRYFKNELKNLGVEIQFGHHATLDSILALRPDAVIFATGVKPREFSLPGMEK
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCH
KKTASYADYLSGKFKPGDQVAIIGGGGIGCDVAHKLTEEDSPTIDSYFHRYNVKSYTNAQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCE
IQKEKPNRKVSIFRRSGKIGSGLGATTAWALLQELESKDVGFYTSLNYKEVTDQGLVVET
EECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCEEEEE
KKDGPITIECDSIILCAGQLSEVSLYEEFKAKFPEIPSYLIGGAKDASGIDAKRAMLEGF
CCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHH
EAALGIGVN
HHHHCCCCC
>Mature Secondary Structure
MKYLEIFQPIQIGSITLPNRVIMGSMHLGLEGMPMPVERMIAFYGRRFDGGACFITTGGI
CCCHHHCCCCEECEEECCCEEEEEEHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCE
AVNHAGRGANIFFNFQKEEDCKELSIVANTLKPKGIFCAQLFHAGRYSYHRDLVAPSAFR
EEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCHHHH
APINRFIPKALSEEEAWKTVEDFGDSALKAKEIGFGAVEVMGSEGYLINQFFSPVTNHRE
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCHH
DFFGGSPEKRMNFAVEVMKNVRKKVGKDFPVIYRMSGIDLIPGNPTFEEVILLAEKLKAT
HHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHHC
GADALNIGIGWHESRIPTISMLVPRGAWAKISGEIKEKIKDIPIIASNRVNMPEVMTRIL
CCCEEEEECCCCCCCCCEEEEEECCCCCHHHCHHHHHHHHCCCEEECCCCCHHHHHHHHH
KNHEADILSMARPFLADPDIVNKIRADQEERINTCIACNQACLDHTFKEQLVSCLVNPSA
HCCCHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
NRELEIGKLKVADKKHVVVVGSGPGGLESARISAIRGHKVTVLEATDKIGGQLNLAAQIP
CCEEEEEEEEECCCCEEEEEECCCCCCCHHHEEEECCCEEEEEECCCCCCCEEEEEEECC
GKSEFFETIRYFKNELKNLGVEIQFGHHATLDSILALRPDAVIFATGVKPREFSLPGMEK
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCH
KKTASYADYLSGKFKPGDQVAIIGGGGIGCDVAHKLTEEDSPTIDSYFHRYNVKSYTNAQ
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCE
IQKEKPNRKVSIFRRSGKIGSGLGATTAWALLQELESKDVGFYTSLNYKEVTDQGLVVET
EECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCEEEEE
KKDGPITIECDSIILCAGQLSEVSLYEEFKAKFPEIPSYLIGGAKDASGIDAKRAMLEGF
CCCCCEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHH
EAALGIGVN
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]