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The map label for this gene is argC

Identifier: 116328241

GI number: 116328241

Start: 1831984

End: 1833000

Strand: Reverse

Name: argC

Synonym: LBL_1568

Alternate gene names: 116328241

Gene position: 1833000-1831984 (Counterclockwise)

Preceding gene: 116328242

Following gene: 116328240

Centisome position: 50.71

GC content: 41.3

Gene sequence:

>1017_bases
ATGGCAGAGATTAGCATTTTAGGAGCAGGCGGTTTGACCGGAAAGGAACTACTTTTGCTTCTTTCCCGCCAAAAGGAACA
CGAAGTCGTTCATATCACGAGTGATAAACTTGCGGGTAAAACACTTGCCGAAGTTTTTCCCGAAATTCCTTTTCCAAAAA
ATCTTACCTTCCACAGCCATGAAGCCGCAATCCCGTCCCAATCCTTAGTCGTCCTAGCTGTGCCCAATAATGTATCAATC
GAGTCAGCTCCTAAATTTTTGGATTCCGGTCACAAAGTAATCGACCTTTCCGGAGCTTATAGACTTCACAATCAAGAAAT
ATTTGAAAAAGCTTATCAATTAAAACATACTCAATTCTCCTATGTGGATAAAGCCGTTTTCGGGATTCCTGAGATTTTTA
GGGACAAATTGAAAAATGCAGATTTCGTTTCCAACCCGGGTTGTTTTTCCACTTCCGTAATTCTTCCGGTATTTTTATTA
AACGAACTCAGAAAAAATCTAAGACCTCGGATTATAGCCGATTCTAAATCGGGTGTTTCCGGCGCGGGTGGAAGAACCGA
AGACGCAGGTTACTCCTATACAGGAGTGTACGAAAACTTTCGAGCTTATAAGATTCTTTCCCATCAACACGAACCGGAAA
TTAAAGAGTACATTTACGCGAATTCGGGACTTCTCGAACCGGAAGTCATTTTCACTCCCCATTTATTACCGGTTTATAGA
GGAATTCTTTCGACGATTGTATTAGAACTTGATACTGAATCTTTCTCTGACCCGATTTCCATTCTACAAAACTCTTGTAA
AAACGAACCTTTCCTTAGAATCTTAAAAACTCCGGAAGAGATCGAACTGAAAAGAGTTCAACATACGAACTTTTTGGATA
TTTCGGTAAGAAAAAGAGGGAATACGTTAGTCATCGTTTCCGCTTTGGACAATCTCATAAAAGGCGCCGCCGGACAAGCG
CTGCAGAACATCAATCTCATGACCGGAACGAAGGAGGTTTTGGGATTATTCCCCTGA

Upstream 100 bases:

>100_bases
CTTGACCGCCGAATGAGAAATCGTTCGGCGTTTTTTTTAATTACGGTATTTTCCAAAAATTAAAATCTTTCTATAAGAGG
GTAAAAAGACAACTAAGATC

Downstream 100 bases:

>100_bases
CTTTTATGGAAAAAGTAAGTCTTTACCATCTACTCAGAGACGTAGCTTCCGTTTATGCGGATCGTCCCCTATATTGGGTT
CGGCAAGAAGACGGCGATTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAEISILGAGGLTGKELLLLLSRQKEHEVVHITSDKLAGKTLAEVFPEIPFPKNLTFHSHEAAIPSQSLVVLAVPNNVSI
ESAPKFLDSGHKVIDLSGAYRLHNQEIFEKAYQLKHTQFSYVDKAVFGIPEIFRDKLKNADFVSNPGCFSTSVILPVFLL
NELRKNLRPRIIADSKSGVSGAGGRTEDAGYSYTGVYENFRAYKILSHQHEPEIKEYIYANSGLLEPEVIFTPHLLPVYR
GILSTIVLELDTESFSDPISILQNSCKNEPFLRILKTPEEIELKRVQHTNFLDISVRKRGNTLVIVSALDNLIKGAAGQA
LQNINLMTGTKEVLGLFP

Sequences:

>Translated_338_residues
MAEISILGAGGLTGKELLLLLSRQKEHEVVHITSDKLAGKTLAEVFPEIPFPKNLTFHSHEAAIPSQSLVVLAVPNNVSI
ESAPKFLDSGHKVIDLSGAYRLHNQEIFEKAYQLKHTQFSYVDKAVFGIPEIFRDKLKNADFVSNPGCFSTSVILPVFLL
NELRKNLRPRIIADSKSGVSGAGGRTEDAGYSYTGVYENFRAYKILSHQHEPEIKEYIYANSGLLEPEVIFTPHLLPVYR
GILSTIVLELDTESFSDPISILQNSCKNEPFLRILKTPEEIELKRVQHTNFLDISVRKRGNTLVIVSALDNLIKGAAGQA
LQNINLMTGTKEVLGLFP
>Mature_337_residues
AEISILGAGGLTGKELLLLLSRQKEHEVVHITSDKLAGKTLAEVFPEIPFPKNLTFHSHEAAIPSQSLVVLAVPNNVSIE
SAPKFLDSGHKVIDLSGAYRLHNQEIFEKAYQLKHTQFSYVDKAVFGIPEIFRDKLKNADFVSNPGCFSTSVILPVFLLN
ELRKNLRPRIIADSKSGVSGAGGRTEDAGYSYTGVYENFRAYKILSHQHEPEIKEYIYANSGLLEPEVIFTPHLLPVYRG
ILSTIVLELDTESFSDPISILQNSCKNEPFLRILKTPEEIELKRVQHTNFLDISVRKRGNTLVIVSALDNLIKGAAGQAL
QNINLMTGTKEVLGLFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=32.3699421965318, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320913, Length=353, Percent_Identity=28.8951841359773, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_LEPBJ (Q04T45)

Other databases:

- EMBL:   CP000350
- RefSeq:   YP_800683.1
- ProteinModelPortal:   Q04T45
- SMR:   Q04T45
- STRING:   Q04T45
- GeneID:   4410202
- GenomeReviews:   CP000350_GR
- KEGG:   lbj:LBJ_1343
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q04T45
- ProtClustDB:   PRK00436
- BioCyc:   LBOR355277:LBJ_1343-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37492; Mature: 37360

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 148-148

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEISILGAGGLTGKELLLLLSRQKEHEVVHITSDKLAGKTLAEVFPEIPFPKNLTFHSH
CCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCC
EAAIPSQSLVVLAVPNNVSIESAPKFLDSGHKVIDLSGAYRLHNQEIFEKAYQLKHTQFS
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHHHHCCCHHH
YVDKAVFGIPEIFRDKLKNADFVSNPGCFSTSVILPVFLLNELRKNLRPRIIADSKSGVS
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GAGGRTEDAGYSYTGVYENFRAYKILSHQHEPEIKEYIYANSGLLEPEVIFTPHLLPVYR
CCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCCEEECCCHHHHHH
GILSTIVLELDTESFSDPISILQNSCKNEPFLRILKTPEEIELKRVQHTNFLDISVRKRG
HHHHHHHHEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCEEEEEEECCC
NTLVIVSALDNLIKGAAGQALQNINLMTGTKEVLGLFP
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
AEISILGAGGLTGKELLLLLSRQKEHEVVHITSDKLAGKTLAEVFPEIPFPKNLTFHSH
CEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCC
EAAIPSQSLVVLAVPNNVSIESAPKFLDSGHKVIDLSGAYRLHNQEIFEKAYQLKHTQFS
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHHHHCCCHHH
YVDKAVFGIPEIFRDKLKNADFVSNPGCFSTSVILPVFLLNELRKNLRPRIIADSKSGVS
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GAGGRTEDAGYSYTGVYENFRAYKILSHQHEPEIKEYIYANSGLLEPEVIFTPHLLPVYR
CCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCCEEECCCHHHHHH
GILSTIVLELDTESFSDPISILQNSCKNEPFLRILKTPEEIELKRVQHTNFLDISVRKRG
HHHHHHHHEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCEEEEEEECCC
NTLVIVSALDNLIKGAAGQALQNINLMTGTKEVLGLFP
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA