| Definition | Leptospira borgpetersenii serovar Hardjo-bovis L550 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008508 |
| Length | 3,614,446 |
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The map label for this gene is fabG [H]
Identifier: 116328201
GI number: 116328201
Start: 1782637
End: 1783407
Strand: Reverse
Name: fabG [H]
Synonym: LBL_1525
Alternate gene names: 116328201
Gene position: 1783407-1782637 (Counterclockwise)
Preceding gene: 116328202
Following gene: 116328200
Centisome position: 49.34
GC content: 40.34
Gene sequence:
>771_bases TTGGAAATTAAAGGTAAAACAGTACTTGTCACCGGCTCAGCAGGCGGGCTTGGAAAGGCTATGGCGGAACATTTTGCCAA AAAAGGGGCAAAAATTGTTCTTTCGGACATATCCGAAGAAAAACTAAAAGAAGCGGAAAAAGATATCAAAGCTTTAGGAG CCGAAGTGCTTTCCTTTAAAGCGGATGTATCCAAAGAAGAAGATGCAGAAAAGCTTATGCAATACGCGGTGAAACATTTT GGAAGTTTAGACGTCGCCATATTGAACGCTGGAATTTTAAGAGACGGATTGTTGGTAAAAACGGATAGAGAAACCGGTAA AGTAATTTCTAAAATGTCATTGGCGAATTGGCAATCCGTTATCGACGTCAATCTTACTGGAGTATTCTTGACCGGAAGGG AAGCAGCAATTCAAATGATAGAAAGTAAGAGTAAAGGCGTTATCGTCCCAATTGCATCCGTTGCGATGCATGGAAATCCG GGGCAGACAAATTATTCCGCTGCAAAAGCTGGAGTTGCCTCAATGACGAAATTATGGGCAAAAGAATTGAGTAGATACGG AATTCGTGTGGCAGGTATTGCACCCGGATTTATAAAAACAGAAATGGTAATGAAGGATATGAATCCCGAAGCGCTAAAAA AATGGGAATCTCTTATACCTATAGGTAGATTAGGAGAACCTTATGAGATTGCATCCTCCGCCGAATTTATCGTTAACAAC GATTTAGTGTCCGGTGTTGTATTAGAAATATCAGGTGGAGTAAAAATTTAA
Upstream 100 bases:
>100_bases AGGATTATAACCGGAGAACATGAAACCACTTCTAGAGTGGAAATTCCATTTTCGAAAAATTATATCAGTGCGAGAAGTAA AGAATTAAAGGAAAATCATC
Downstream 100 bases:
>100_bases TCGGAAATCATCTTTTTAAGAAAAGAACTTTACAGTAAGATAAAATTATAATAAAATAGACTGTAATTTATCGAATCGAG ATTTGCTAGTTTACTGAAAT
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MEIKGKTVLVTGSAGGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKALGAEVLSFKADVSKEEDAEKLMQYAVKHF GSLDVAILNAGILRDGLLVKTDRETGKVISKMSLANWQSVIDVNLTGVFLTGREAAIQMIESKSKGVIVPIASVAMHGNP GQTNYSAAKAGVASMTKLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWESLIPIGRLGEPYEIASSAEFIVNN DLVSGVVLEISGGVKI
Sequences:
>Translated_256_residues MEIKGKTVLVTGSAGGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKALGAEVLSFKADVSKEEDAEKLMQYAVKHF GSLDVAILNAGILRDGLLVKTDRETGKVISKMSLANWQSVIDVNLTGVFLTGREAAIQMIESKSKGVIVPIASVAMHGNP GQTNYSAAKAGVASMTKLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWESLIPIGRLGEPYEIASSAEFIVNN DLVSGVVLEISGGVKI >Mature_256_residues MEIKGKTVLVTGSAGGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKALGAEVLSFKADVSKEEDAEKLMQYAVKHF GSLDVAILNAGILRDGLLVKTDRETGKVISKMSLANWQSVIDVNLTGVFLTGREAAIQMIESKSKGVIVPIASVAMHGNP GQTNYSAAKAGVASMTKLWAKELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWESLIPIGRLGEPYEIASSAEFIVNN DLVSGVVLEISGGVKI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=36.9047619047619, Blast_Score=145, Evalue=4e-35, Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=32.5757575757576, Blast_Score=135, Evalue=5e-32, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=34.7328244274809, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=32.0610687022901, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=29.0196078431373, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI4504505, Length=232, Percent_Identity=31.4655172413793, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=26.5151515151515, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI59889578, Length=242, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI31542939, Length=266, Percent_Identity=25.187969924812, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=26.8595041322314, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=27.734375, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=28.1407035175879, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI142976729, Length=251, Percent_Identity=26.2948207171315, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4503301, Length=231, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=26.6009852216749, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI209862901, Length=209, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI19923983, Length=209, Percent_Identity=24.4019138755981, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI224922801, Length=183, Percent_Identity=27.3224043715847, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=27.3684210526316, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI40807363, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=33.4630350194552, Blast_Score=130, Evalue=8e-32, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=30.8880308880309, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=33.0739299610895, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=31.7829457364341, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=30.859375, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=31.5589353612167, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.1338582677165, Blast_Score=94, Evalue=6e-21, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=28.6274509803922, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=29.277566539924, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=26.5625, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787526, Length=228, Percent_Identity=25.8771929824561, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789057, Length=212, Percent_Identity=26.8867924528302, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=26.5625, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1788891, Length=271, Percent_Identity=22.8782287822878, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=36.328125, Blast_Score=137, Evalue=5e-33, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=34.5098039215686, Blast_Score=135, Evalue=2e-32, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=28.957528957529, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=31.2741312741313, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=30.3030303030303, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=30.6513409961686, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=30.078125, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=27.7992277992278, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17568967, Length=224, Percent_Identity=29.9107142857143, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.125, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562904, Length=250, Percent_Identity=29.2, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI193203115, Length=223, Percent_Identity=31.8385650224215, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=27.4131274131274, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=27.6923076923077, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI193203117, Length=224, Percent_Identity=31.6964285714286, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=29.1497975708502, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=30.6513409961686, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=26.4367816091954, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=27.1062271062271, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17564282, Length=242, Percent_Identity=29.7520661157025, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17563726, Length=249, Percent_Identity=31.3253012048193, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=28.125, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17538486, Length=254, Percent_Identity=26.7716535433071, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=248, Percent_Identity=30.241935483871, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=27.3076923076923, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI72000259, Length=248, Percent_Identity=29.4354838709677, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17567345, Length=216, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=25.78125, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=28.4046692607004, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=27.7372262773723, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17561272, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17560332, Length=251, Percent_Identity=26.6932270916335, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI32563809, Length=222, Percent_Identity=26.5765765765766, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17507613, Length=222, Percent_Identity=26.5765765765766, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17508895, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=27.734375, Blast_Score=67, Evalue=9e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=37.0212765957447, Blast_Score=112, Evalue=5e-26, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=31.5384615384615, Blast_Score=90, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6323882, Length=205, Percent_Identity=30.2439024390244, Blast_Score=75, Evalue=9e-15, Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=37.3076923076923, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=38.1679389312977, Blast_Score=134, Evalue=4e-32, Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=29.8850574712644, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24644339, Length=265, Percent_Identity=31.6981132075472, Blast_Score=107, Evalue=6e-24, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=31.5384615384615, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=30.0813008130081, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=29.6153846153846, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI18859837, Length=204, Percent_Identity=31.3725490196078, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=29.811320754717, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI281364494, Length=215, Percent_Identity=29.7674418604651, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24641232, Length=221, Percent_Identity=25.7918552036199, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24649181, Length=207, Percent_Identity=29.951690821256, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24640492, Length=205, Percent_Identity=28.2926829268293, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI281364892, Length=205, Percent_Identity=28.2926829268293, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584752, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641388, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24665243, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI221331218, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI116007236, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27318; Mature: 27318
Theoretical pI: Translated: 9.23; Mature: 9.23
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEIKGKTVLVTGSAGGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKALGAEVLSFK CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH ADVSKEEDAEKLMQYAVKHFGSLDVAILNAGILRDGLLVKTDRETGKVISKMSLANWQSV HCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHE IDVNLTGVFLTGREAAIQMIESKSKGVIVPIASVAMHGNPGQTNYSAAKAGVASMTKLWA EEEEEEEEEEECHHHHHHHHHCCCCCEEEEEHHEEECCCCCCCCHHHHHHHHHHHHHHHH KELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWESLIPIGRLGEPYEIASSAEFIVNN HHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEC DLVSGVVLEISGGVKI CCCCEEEEEECCCCCC >Mature Secondary Structure MEIKGKTVLVTGSAGGLGKAMAEHFAKKGAKIVLSDISEEKLKEAEKDIKALGAEVLSFK CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH ADVSKEEDAEKLMQYAVKHFGSLDVAILNAGILRDGLLVKTDRETGKVISKMSLANWQSV HCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHE IDVNLTGVFLTGREAAIQMIESKSKGVIVPIASVAMHGNPGQTNYSAAKAGVASMTKLWA EEEEEEEEEEECHHHHHHHHHCCCCCEEEEEHHEEECCCCCCCCHHHHHHHHHHHHHHHH KELSRYGIRVAGIAPGFIKTEMVMKDMNPEALKKWESLIPIGRLGEPYEIASSAEFIVNN HHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEC DLVSGVVLEISGGVKI CCCCEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]