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The map label for this gene is dtpD [H]

Identifier: 116328170

GI number: 116328170

Start: 1741111

End: 1742415

Strand: Direct

Name: dtpD [H]

Synonym: LBL_1486

Alternate gene names: 116328170

Gene position: 1741111-1742415 (Clockwise)

Preceding gene: 116328169

Following gene: 116328171

Centisome position: 48.17

GC content: 42.53

Gene sequence:

>1305_bases
ATGGACATCCAGGGCCAAAATCTGAATTCACATCCGAAAGGTCTCTCCATTTTGTTTTTCACGGAAACTTGGGAGAGATT
CAGTTTCTACGGAATGCGTGCCTTACTTGTGTTATTCCTCACCAAAGTTTTTCACTTTTCGGATCCGAATGCAAATCGAA
TCTACGGTATTTACACAGGTCTCGTTTATTTAACTCCTCTCGCAGGAGGTTATCTCGCAGATCGTTATTTGGGTTTTAAG
AAGTCCATTCTTCTGGGAACGACTCTCATGATGTTCGGACATCTAAGTCTCGCTTTTGAAACAAAACCGTTTTTTCTTTT
GGGATTGACCCTGCTCATCATTGGAGTCGGTTTTTTTAAACCCAACATCTCCACAGTCGTGGGAAGAATCTACGAAGAAG
ACAAGAAAACTCACATGAAAGATTCTGGTTTTACAATTTTTTATATGGGAATCAATCTTGGTGGTTTTTTAGGACCTCTT
TTCTGCGGATATTTCAGCGAGTCTTTCGGTTGGGGTTACGGATTCGGTGTGGCCGCCTTCGGTGTGTTATTCGGAATTTT
GATTTTTCTTTTCGGACAAAAAAGATTTTCGGATCGGGTTTTCGAACCAGGCAAAAAGAATCGTATCGACAAAGGATACA
GGCATTCTCCTTTAACGAAAGAAGAAAAGCGAAGAGTTATTATCGTTCTGATTTTTACCGCGTTTGCGATCATTTTCTGG
GCGGTGTTCGAACAAATTGGTTCTTCTATGAATCTGTTCATCGATCGTCACGTGGATCGAAATTGGTTCGGTTACGATAT
TCCTACTCCTTTTTTTCAATCTTTAAATCCGCTTTTGATTTTGAGTTTAGCGCCCGCGATCGCTTCTTTTTGGACTGCCC
TTTCCAAAAGGGGCTGGAAACCGGATACTTCCACGAGGTTTGTTTGCGGTTTTTTTATTTTGGGCTCCGGGTTTTTAATT
CTAACATTAGCCACCATTGACTTTCGAATCGGTCACAAGATCTCAGCGGTCTGGCTTTTTTTAATGGTTCTTTGTATTAC
GATCGGAGAATTGTTCACTTCTCCAGGCGGACTTTCACTTGTCACGAAGCTGGCTCCGAATCATCTCGGTGGGTTTATGA
TGGGCGTTTGGTTTCTTTCCAGTTTTTTCGGCAATATTCTTGCCGGAGAATTAGCGGGTCTTATGAAAACGGACAACTTC
TCTACGTTTTTCGGAATGTTTGCGGGGTTTGCATTTGCGGGAGGAGGTGCTCTTTATCTCGTGCAAAAGAGGCTCCGAGT
TTGGATGCGCGGTCTGGATTTCTAA

Upstream 100 bases:

>100_bases
AGATTCTTTCCCCTCCCATGGTGTTTATCAATCGTCTTTCGGATTTCTTTTTTGTTGCCGCTCGTTTTGCAAATTTAGAA
GAGAATATTCAGGAACCTTT

Downstream 100 bases:

>100_bases
AAGGATGAACTTTTATATATTCTCAAATTTATATATTAGGAGATTTTGATGTTTCGAATTCTAGTGATCTTTTGGGCCCT
TGTTTGGTTTTCTGTGTCCG

Product: dipeptide/tripeptide permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDIQGQNLNSHPKGLSILFFTETWERFSFYGMRALLVLFLTKVFHFSDPNANRIYGIYTGLVYLTPLAGGYLADRYLGFK
KSILLGTTLMMFGHLSLAFETKPFFLLGLTLLIIGVGFFKPNISTVVGRIYEEDKKTHMKDSGFTIFYMGINLGGFLGPL
FCGYFSESFGWGYGFGVAAFGVLFGILIFLFGQKRFSDRVFEPGKKNRIDKGYRHSPLTKEEKRRVIIVLIFTAFAIIFW
AVFEQIGSSMNLFIDRHVDRNWFGYDIPTPFFQSLNPLLILSLAPAIASFWTALSKRGWKPDTSTRFVCGFFILGSGFLI
LTLATIDFRIGHKISAVWLFLMVLCITIGELFTSPGGLSLVTKLAPNHLGGFMMGVWFLSSFFGNILAGELAGLMKTDNF
STFFGMFAGFAFAGGGALYLVQKRLRVWMRGLDF

Sequences:

>Translated_434_residues
MDIQGQNLNSHPKGLSILFFTETWERFSFYGMRALLVLFLTKVFHFSDPNANRIYGIYTGLVYLTPLAGGYLADRYLGFK
KSILLGTTLMMFGHLSLAFETKPFFLLGLTLLIIGVGFFKPNISTVVGRIYEEDKKTHMKDSGFTIFYMGINLGGFLGPL
FCGYFSESFGWGYGFGVAAFGVLFGILIFLFGQKRFSDRVFEPGKKNRIDKGYRHSPLTKEEKRRVIIVLIFTAFAIIFW
AVFEQIGSSMNLFIDRHVDRNWFGYDIPTPFFQSLNPLLILSLAPAIASFWTALSKRGWKPDTSTRFVCGFFILGSGFLI
LTLATIDFRIGHKISAVWLFLMVLCITIGELFTSPGGLSLVTKLAPNHLGGFMMGVWFLSSFFGNILAGELAGLMKTDNF
STFFGMFAGFAFAGGGALYLVQKRLRVWMRGLDF
>Mature_434_residues
MDIQGQNLNSHPKGLSILFFTETWERFSFYGMRALLVLFLTKVFHFSDPNANRIYGIYTGLVYLTPLAGGYLADRYLGFK
KSILLGTTLMMFGHLSLAFETKPFFLLGLTLLIIGVGFFKPNISTVVGRIYEEDKKTHMKDSGFTIFYMGINLGGFLGPL
FCGYFSESFGWGYGFGVAAFGVLFGILIFLFGQKRFSDRVFEPGKKNRIDKGYRHSPLTKEEKRRVIIVLIFTAFAIIFW
AVFEQIGSSMNLFIDRHVDRNWFGYDIPTPFFQSLNPLLILSLAPAIASFWTALSKRGWKPDTSTRFVCGFFILGSGFLI
LTLATIDFRIGHKISAVWLFLMVLCITIGELFTSPGGLSLVTKLAPNHLGGFMMGVWFLSSFFGNILAGELAGLMKTDNF
STFFGMFAGFAFAGGGALYLVQKRLRVWMRGLDF

Specific function: Probable proton-dependent permease that transports dipeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpD subfamily [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=322, Percent_Identity=26.0869565217391, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4827008, Length=370, Percent_Identity=25.4054054054054, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI226371748, Length=312, Percent_Identity=25.6410256410256, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786927, Length=450, Percent_Identity=32.8888888888889, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1790572, Length=441, Percent_Identity=29.0249433106576, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1787922, Length=439, Percent_Identity=27.1070615034169, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789911, Length=427, Percent_Identity=25.7611241217799, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71987453, Length=326, Percent_Identity=27.9141104294479, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17569141, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639585, Length=319, Percent_Identity=30.4075235109718, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24639583, Length=319, Percent_Identity=30.4075235109718, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24639581, Length=319, Percent_Identity=30.4075235109718, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571098, Length=330, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571102, Length=330, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571100, Length=330, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 48794; Mature: 48794

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQGQNLNSHPKGLSILFFTETWERFSFYGMRALLVLFLTKVFHFSDPNANRIYGIYTG
CCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
LVYLTPLAGGYLADRYLGFKKSILLGTTLMMFGHLSLAFETKPFFLLGLTLLIIGVGFFK
HHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCC
PNISTVVGRIYEEDKKTHMKDSGFTIFYMGINLGGFLGPLFCGYFSESFGWGYGFGVAAF
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
GVLFGILIFLFGQKRFSDRVFEPGKKNRIDKGYRHSPLTKEEKRRVIIVLIFTAFAIIFW
HHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHHHH
AVFEQIGSSMNLFIDRHVDRNWFGYDIPTPFFQSLNPLLILSLAPAIASFWTALSKRGWK
HHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
PDTSTRFVCGFFILGSGFLILTLATIDFRIGHKISAVWLFLMVLCITIGELFTSPGGLSL
CCCCCHHHHHHHHHHCCHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VTKLAPNHLGGFMMGVWFLSSFFGNILAGELAGLMKTDNFSTFFGMFAGFAFAGGGALYL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
VQKRLRVWMRGLDF
HHHHHHHHHHCCCC
>Mature Secondary Structure
MDIQGQNLNSHPKGLSILFFTETWERFSFYGMRALLVLFLTKVFHFSDPNANRIYGIYTG
CCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
LVYLTPLAGGYLADRYLGFKKSILLGTTLMMFGHLSLAFETKPFFLLGLTLLIIGVGFFK
HHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCC
PNISTVVGRIYEEDKKTHMKDSGFTIFYMGINLGGFLGPLFCGYFSESFGWGYGFGVAAF
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
GVLFGILIFLFGQKRFSDRVFEPGKKNRIDKGYRHSPLTKEEKRRVIIVLIFTAFAIIFW
HHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCEEEEHHHHHHHHHHH
AVFEQIGSSMNLFIDRHVDRNWFGYDIPTPFFQSLNPLLILSLAPAIASFWTALSKRGWK
HHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
PDTSTRFVCGFFILGSGFLILTLATIDFRIGHKISAVWLFLMVLCITIGELFTSPGGLSL
CCCCCHHHHHHHHHHCCHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VTKLAPNHLGGFMMGVWFLSSFFGNILAGELAGLMKTDNFSTFFGMFAGFAFAGGGALYL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
VQKRLRVWMRGLDF
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA