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The map label for this gene is accA [H]

Identifier: 116328155

GI number: 116328155

Start: 1712661

End: 1714313

Strand: Direct

Name: accA [H]

Synonym: LBL_1465

Alternate gene names: 116328155

Gene position: 1712661-1714313 (Clockwise)

Preceding gene: 116328154

Following gene: 116328156

Centisome position: 47.38

GC content: 44.83

Gene sequence:

>1653_bases
ATGTCCGAAGCAAAGTATTCACTGGAAAATCCATTTCAATCCACGACCGAACCTAATGTTCTTAAAACCCGCGGTCTTTA
CGAAGAGGCAAACGAGTTAGGAAAAGAACTCCTCAACAAACCACTAGTGGGAGGAGGAGTCGACAGAATCCTCGTTCAAC
ATTCCAAAGAAAGGATGACTGTCTGGGAAAGGATTAAGGTTCTTACGGAAAAAGAACCCAATATACTCTACCAAAACTGG
GGAAAAAGTTTGGACGGAGCTTCTCTGGTTACCGGAATTTTAAATATCAACGGTAGGGATGTGGCGATTTACGGTCACGA
CTTCACTCTTCGCGCGGGTTCGATGGATGCGACTAACGGAAGTAAACTTGCCAGATTGATCTATATGGCAGGAGAGCACG
GAATTCCTTTGATTGGAATGAACGATTCTGCCGGAGCTTATGTTCCTGCGGGAGTGGGTGGACTGGACGGTTATAGCGAG
GCATTTACAGCGCTTCGGAAAATCAGCGGAGTTGTTCCAAGTTTGATGCTCATGTTCGGATTCAATGCGGGAGGGGGAGC
TTACCTTCCACGACAAGGATCGTTTATGATCCAATGTGATAATACTTTCTTCGGTTTAACGGGACCCGGAGTCGTTAAAT
CGGTCTTAGGCGAAGATATCTCCGCGGATGATTTAGGCGGACCCAAAGTTCATGGTCAGAGCGGAGTGGTTGATATCGTA
ACCGGTGACGAGTTGGGATCCCTTCGGACCGCTCTTCGTTTGCTTTCTTATCTGCCGGATAACAATCATTCCTTTGCACC
ATTTCATGCTACTTCCGATCCCACGAATCGATTTATATACGAGGAAGAGATTCTTTTTAAGAAAACCTTTAATTCTCCTA
CAGGAATGAACACGCCTTTCGATATCACTTTGTATTTGCAGAACATCTGTGATCACGGACAATACTTTGAAATCCAGGGA
CAACGTTCCAGAAACTTAGTCACCGCCTTTGGAAGAATCGGTGGACATGTGATAGCGTTTGTCGCAAATAACTCCGCTGT
TTCTTCCGGACAAATCGATATCGGTGCCGCAAGAAAAGGAACGCGTTTTATCCGTTTTTGCAACCTTTACAATATACCGA
TCGTTTTTTTAGAGGATACGACAGGATTTTTGCCCGGAAAAGAACAGGAACAAAACGGAATCGTTCTCGAAGGAAGAAAA
CTTTTGGATTCCATCATTGATATCCGCACTCCTCGTCTAACTCTAATTATTCGAAATGCGTTCGGAGGAGCTTACGCTTG
TTTTAATTCGTATCACACGGGAGCGGATATGGTATTCGCGCTTCCTACCGCTAGGATCGCGGTAATGGGGCCGGCGGGCA
AAGACTACGTTTATAAGGACGAAGTGTCTTCGATCCAAAAAGAATATCAGGAAAATGTAAAGAAGGGAATGTCCGAAAAG
GAGGCCGTCGTAATTCGGGATAAAAAGCTTCAAACGCTTTCCACACAGTACGAAAGGGAACTGATGAACCCGAAAGAAGC
TCTTTCATTAGGTTCCGTTTCCAGAATTGTTCTTCCCGGAACGACCAGGAATATTCTCTTTCAAAATCTGGATTATTTAA
TTCGACATTATAAACCGGCTCCATTGTCCGGACCTCAAAGGGAGTTTGAGTAA

Upstream 100 bases:

>100_bases
ATAAAATAACTTCCCCCGACGTACTAAGGCCGAATTTAACTTTCCTGAGAATCCTTTCTTTAAAAACTGGATTTATTTTA
TTTCATTGAAAGGTTCTCGC

Downstream 100 bases:

>100_bases
TCTACATGATTGACTTTCACAACAATCGCATTCAATTTCATCAATCCAATTCTCCTTGGATCCGTTCCTTCTCTTTGGAA
TCGATCAAATGTCTGATCGT

Product: Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSEAKYSLENPFQSTTEPNVLKTRGLYEEANELGKELLNKPLVGGGVDRILVQHSKERMTVWERIKVLTEKEPNILYQNW
GKSLDGASLVTGILNINGRDVAIYGHDFTLRAGSMDATNGSKLARLIYMAGEHGIPLIGMNDSAGAYVPAGVGGLDGYSE
AFTALRKISGVVPSLMLMFGFNAGGGAYLPRQGSFMIQCDNTFFGLTGPGVVKSVLGEDISADDLGGPKVHGQSGVVDIV
TGDELGSLRTALRLLSYLPDNNHSFAPFHATSDPTNRFIYEEEILFKKTFNSPTGMNTPFDITLYLQNICDHGQYFEIQG
QRSRNLVTAFGRIGGHVIAFVANNSAVSSGQIDIGAARKGTRFIRFCNLYNIPIVFLEDTTGFLPGKEQEQNGIVLEGRK
LLDSIIDIRTPRLTLIIRNAFGGAYACFNSYHTGADMVFALPTARIAVMGPAGKDYVYKDEVSSIQKEYQENVKKGMSEK
EAVVIRDKKLQTLSTQYERELMNPKEALSLGSVSRIVLPGTTRNILFQNLDYLIRHYKPAPLSGPQREFE

Sequences:

>Translated_550_residues
MSEAKYSLENPFQSTTEPNVLKTRGLYEEANELGKELLNKPLVGGGVDRILVQHSKERMTVWERIKVLTEKEPNILYQNW
GKSLDGASLVTGILNINGRDVAIYGHDFTLRAGSMDATNGSKLARLIYMAGEHGIPLIGMNDSAGAYVPAGVGGLDGYSE
AFTALRKISGVVPSLMLMFGFNAGGGAYLPRQGSFMIQCDNTFFGLTGPGVVKSVLGEDISADDLGGPKVHGQSGVVDIV
TGDELGSLRTALRLLSYLPDNNHSFAPFHATSDPTNRFIYEEEILFKKTFNSPTGMNTPFDITLYLQNICDHGQYFEIQG
QRSRNLVTAFGRIGGHVIAFVANNSAVSSGQIDIGAARKGTRFIRFCNLYNIPIVFLEDTTGFLPGKEQEQNGIVLEGRK
LLDSIIDIRTPRLTLIIRNAFGGAYACFNSYHTGADMVFALPTARIAVMGPAGKDYVYKDEVSSIQKEYQENVKKGMSEK
EAVVIRDKKLQTLSTQYERELMNPKEALSLGSVSRIVLPGTTRNILFQNLDYLIRHYKPAPLSGPQREFE
>Mature_549_residues
SEAKYSLENPFQSTTEPNVLKTRGLYEEANELGKELLNKPLVGGGVDRILVQHSKERMTVWERIKVLTEKEPNILYQNWG
KSLDGASLVTGILNINGRDVAIYGHDFTLRAGSMDATNGSKLARLIYMAGEHGIPLIGMNDSAGAYVPAGVGGLDGYSEA
FTALRKISGVVPSLMLMFGFNAGGGAYLPRQGSFMIQCDNTFFGLTGPGVVKSVLGEDISADDLGGPKVHGQSGVVDIVT
GDELGSLRTALRLLSYLPDNNHSFAPFHATSDPTNRFIYEEEILFKKTFNSPTGMNTPFDITLYLQNICDHGQYFEIQGQ
RSRNLVTAFGRIGGHVIAFVANNSAVSSGQIDIGAARKGTRFIRFCNLYNIPIVFLEDTTGFLPGKEQEQNGIVLEGRKL
LDSIIDIRTPRLTLIIRNAFGGAYACFNSYHTGADMVFALPTARIAVMGPAGKDYVYKDEVSSIQKEYQENVKKGMSEKE
AVVIRDKKLQTLSTQYERELMNPKEALSLGSVSRIVLPGTTRNILFQNLDYLIRHYKPAPLSGPQREFE

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=531, Percent_Identity=32.9566854990584, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI295821216, Length=551, Percent_Identity=31.7604355716878, Blast_Score=269, Evalue=6e-72,
Organism=Homo sapiens, GI11545863, Length=447, Percent_Identity=27.5167785234899, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI38679960, Length=317, Percent_Identity=25.8675078864353, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679974, Length=317, Percent_Identity=25.8675078864353, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679971, Length=317, Percent_Identity=25.8675078864353, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679977, Length=317, Percent_Identity=25.8675078864353, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38679967, Length=317, Percent_Identity=25.8675078864353, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI134142062, Length=365, Percent_Identity=24.9315068493151, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25147362, Length=512, Percent_Identity=32.8125, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI25147359, Length=512, Percent_Identity=32.8125, Blast_Score=281, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17552936, Length=528, Percent_Identity=26.1363636363636, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323863, Length=354, Percent_Identity=21.1864406779661, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586065, Length=531, Percent_Identity=26.5536723163842, Blast_Score=158, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 60381; Mature: 60249

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKYSLENPFQSTTEPNVLKTRGLYEEANELGKELLNKPLVGGGVDRILVQHSKERMT
CCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHH
VWERIKVLTEKEPNILYQNWGKSLDGASLVTGILNINGRDVAIYGHDFTLRAGSMDATNG
HHHHHHHHHCCCCCEEHHHCCCCCCCHHHHHHHEECCCCEEEEECCCEEEECCCCCCCCC
SKLARLIYMAGEHGIPLIGMNDSAGAYVPAGVGGLDGYSEAFTALRKISGVVPSLMLMFG
HHHEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
FNAGGGAYLPRQGSFMIQCDNTFFGLTGPGVVKSVLGEDISADDLGGPKVHGQSGVVDIV
CCCCCCCCCCCCCCEEEEECCEEECCCCHHHHHHHHCCCCCCCCCCCCEECCCCCEEEEE
TGDELGSLRTALRLLSYLPDNNHSFAPFHATSDPTNRFIYEEEILFKKTFNSPTGMNTPF
ECCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEHHHHHEEECCCCCCCCCCCE
DITLYLQNICDHGQYFEIQGQRSRNLVTAFGRIGGHVIAFVANNSAVSSGQIDIGAARKG
EEEEEEHHHHCCCCEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCCC
TRFIRFCNLYNIPIVFLEDTTGFLPGKEQEQNGIVLEGRKLLDSIIDIRTPRLTLIIRNA
CEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEEEEC
FGGAYACFNSYHTGADMVFALPTARIAVMGPAGKDYVYKDEVSSIQKEYQENVKKGMSEK
CCCHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCC
EAVVIRDKKLQTLSTQYERELMNPKEALSLGSVSRIVLPGTTRNILFQNLDYLIRHYKPA
CEEEEECCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
PLSGPQREFE
CCCCCCCCCC
>Mature Secondary Structure 
SEAKYSLENPFQSTTEPNVLKTRGLYEEANELGKELLNKPLVGGGVDRILVQHSKERMT
CCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHH
VWERIKVLTEKEPNILYQNWGKSLDGASLVTGILNINGRDVAIYGHDFTLRAGSMDATNG
HHHHHHHHHCCCCCEEHHHCCCCCCCHHHHHHHEECCCCEEEEECCCEEEECCCCCCCCC
SKLARLIYMAGEHGIPLIGMNDSAGAYVPAGVGGLDGYSEAFTALRKISGVVPSLMLMFG
HHHEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
FNAGGGAYLPRQGSFMIQCDNTFFGLTGPGVVKSVLGEDISADDLGGPKVHGQSGVVDIV
CCCCCCCCCCCCCCEEEEECCEEECCCCHHHHHHHHCCCCCCCCCCCCEECCCCCEEEEE
TGDELGSLRTALRLLSYLPDNNHSFAPFHATSDPTNRFIYEEEILFKKTFNSPTGMNTPF
ECCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEHHHHHEEECCCCCCCCCCCE
DITLYLQNICDHGQYFEIQGQRSRNLVTAFGRIGGHVIAFVANNSAVSSGQIDIGAARKG
EEEEEEHHHHCCCCEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCCCC
TRFIRFCNLYNIPIVFLEDTTGFLPGKEQEQNGIVLEGRKLLDSIIDIRTPRLTLIIRNA
CEEEEEEEEECCCEEEEECCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEEEEC
FGGAYACFNSYHTGADMVFALPTARIAVMGPAGKDYVYKDEVSSIQKEYQENVKKGMSEK
CCCHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCC
EAVVIRDKKLQTLSTQYERELMNPKEALSLGSVSRIVLPGTTRNILFQNLDYLIRHYKPA
CEEEEECCHHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
PLSGPQREFE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]